천일제염에 있어서 海鹹水의 증발촉진에 관한 연구 : Dye Stuff-Solivap Green의 利用을 中心으로

李重和 세종대학교 1971 세종대학 논문집 Vol.5 No.-

In this study, writer carried out this solar evaporation and concentration of sea water using special dye-stuff-“Solivap-Green”. Factors influencing solar evaporation are; 1. Initial salinity 2. rate of natural evaporation 3. rainfall 4. seepage Additives (dye stuff) which are capable of increasing the absorption of solar energy without substantially affecting production costs are desirable. Required property of additives for optimum efficiency are; 1. good solubility in sea water and highly concentrated brine 2. high absorption of solar radiation 3. high light fastness for lengthly sun exposure “Solivap Green”brands meet these requirement. The results obtained were as follows; 1. Salt production increase is over 25% in case the dye stuff is used in the salt crystallzing area, but the quality of the salt is not highly agreeable because salt is stained by the stuff. And it is recommened to apply the method during the dry weather, when the loss rate of salt brine by being swept is low, rather than rainy season. 2. Salt production increase is also over 29% when the dye stuff is used in the evaporating area but this method still has defect, for a large amount of dye stuff is needed.

정신분열병 입원 환자에서 단축형 증상관리 훈련의 효과:예비적 연구

최충식,채정호,우동원,최영희,함웅,이규항,장미화 대한신경정신의학회 2001 신경정신의학 Vol.40 No.1

연구목적: 정신분열병 환자에서의 재활치료는 개인의 극복 기술과 능력을 향상시키고 재발을 유발시킬 수 있는 스트레스의 부정적인 영향을 중화시킴으로써 질병의 만성화를 막고 사회기능을 호전시킬 수 있기에 점차 그 중요성이 대두되고 있다. 본 연구는 만성 정신분열병 입원 환자에서 재활치료의 하나인 단축형 증상관리 훈련이 정신장애에 대한 자기 인식에 미치는 효능을 알아보기 위하여 시행되었다. 방법: 정신분열병으로 진단받고 입원 중인 환자들에게 재발경고징후를 규명하는 것, 재발경고징후를 관리하는 것, 지속증상을 극복하는 것, 술과 불법 약물을 피하는 것 등으로 구성된 승인-UCLA 사회기술 및 독립적인 생활기술훈련 단위 중 증상관리단위를 기초로 한국실정에 맞게 축약한 증산관리 훈련을 주 1회, 60분씩, 4∼5주간 실시하였고 실시 전후에 전신장애 비인식 평가 척도(Scale to Assess Unawareness ofMental Disorder; 이하 SUMD)로 자신의 정신장애에 대한 인식을 평가하였으며 임상적 전반적 인상(Clinical Global Impression;이하 CGI)로 임상 상태를 조사하였고 각 인구학적 변인들을 조사하였다. 결과: 환자 30명이 훈련을 완수하였으며 이들의 평균 연령은 36.6±7.6세였고 남자가 14명(46.7%), 여자가16명(53.3%)이었다. SUMD 점수는 훈련 전 16.9±4.0점에서 훈련 후 12.9±4.2점으로 유의하게 줄어 정신장애에 대한 자기 인식 정도가 향상되었으며(p<0.01), CGI도 훈련전의 3.7±0.9점에서 훈련 후 2.8±0.8점으로 유의하게 호전되었다(p<0.01). 환자의 연령, 발병시 연령, 유병 기간, 입원 기간, 항정신병약물 사용 용량, 교육 정도, CGI로 평가한 임상 상태등은 정신장애의 자기 인식 정도와는 관련성이 없었다. 결론: 정신분열병 입원 환자에서 단축형 증상관리 훈련은 정신장애에 대한 자기 인식을 증가시킬 수 있는 방법이 될 가능성을 확인하였으며 이 방법이 정신분열병 재활치료의 중요한 요소가 될 수 있음을 알 수 있었다. Objectives : The purpose of this study was to examine whether Symptom Management Module-Korean Brief Version(SMM-B) is effective as a psychosocial treatment of the inpat-ients with chronic schizophrenia. We also questioned which of demographic and clinical characteristics could be predictors of differential treatment response. Methods : The subjects were composed of 30 inpatients with chronic schizophrenia, who were trained with weekly session of SMM-B for 5 weeks. Before and after the training, the level of psychopathology, knowledge about schizophrenia were assessed as dependent variables by using Clinical Global Impression(CGI) and Scale to Assess Unawareness of Mental Disorder(SUMD). Results : Overall, patients showed improvement over the treatment period on psychopath-ology as well as knowledge about psychosis. Total scores of SUMD were changed from 16.9±4.0 before training to 12.9±4.2 after training(p<0.01) and scores of CGI were improved from 3.7±0.9 to 2.8±0.8<p<0.01). Howver age, gender, years of education, age of onset, duration of illness, duration of admission, numbers of psychiatric admission, and clinical status evaluated by CGI were not correlated with unawareness of psychosis. Conclusion : These results suggest that SMM-B could be a reliable method to improve self-aw-areness of psychosis in patients whth chronic schizophrenia and one of important elements in rehabilitation.

Leukemoid Reaction와 임상적 고찰

이우형,유병희,김화숙,이학중 大韓血液學會 1982 大韓血液學會誌 Vol.17 No.2

쌍발 복합재 항공기의 세로 안정 미계수 추정

김칠영,이정모,은희봉,신충화,황명신 한국 항공대학교 항공산업기술연구소 1997 航空宇宙産業技術硏究所 硏究誌 Vol.7 No.-

본 연구의 목적은 비행시험으로부터 항공기의 동적 세로 안정 미계수를 결정하는 것이다. 일반적으로 미계수를 결정하는 방법은 풍동시험 방법, 분석적 방법 그리고 비행시험 방법등으로 나누어진다. 앞의 두가지 방법은 미계수 추정에 있어 많은 제한을 갖고 있으며 추정된 미계수의 유효성에도 문제가 있다. 따라서 비행 시험은 가장 정확한 미계수를 얻을 수 있는 방법이며 반드시 필요한 절차이다. 쌍발 복합재 항공기의 비행시험을 통해 자료를 획득하였고 최대공산법을 이용하여 세로 조종/안정 미계수를 추정하였다. 추정된 미계수를 이용하여 항공기의 운동을 시뮬레이션하여 실제 시험자료와 비교하여 좋은 결과를 나타냄을 알 수 있었다. The purpose of this paper is to find how to determine the longitudinal controllability and stability derivatives from flight test and to display the longitudinal stability of the Twinbee aircraft. There are various methods developed to find the derivatives : wind tunnel testing, predicted result from empirical data, flight test and so on. Among those methods, the estimation from flight test of real aircraft is the most reliable. We performed the flight test of Twinbee and recorded the states of aircraft. Using those states and parameter estimation algorithem based on the Maximum Likelihood (MMLE) criterion, we can estimate the controllability and stability derivatives. In this paper, we will show the process from designing the proper flight test input to estimation of derivatives.

만성 간장 질환자에서 뇌 MRI 상의 pallidal index와 생물학적 망간지표들 간의 관련성

최영희,박능화,신정우,김효경,김성률,정태흠,박지강,이헌,유철인,이충렬,이지호,김양호 大韓産業醫學會 2004 대한직업환경의학회지 Vol.16 No.2

목적 : 만성 간장 질환자를 대상으로 T1강조 자기공명영상(MRI)에서 나타나는 담창구 부위의 고신호강도 소견(pallidal index, PI)과 생물학적 망간 지표들 간의 관련성을 알아본다. 방법 : B형간염 바이러스에 의한 간경변증으로 진단 받은 40세 이상의 환자 31명과 정상 대조군 10명을 대상으로 설문조사와 혈액 및 소변검사, 뇌 MRI를 시행하였다. 전체 41명 가운데 검사 전 수혈을 받았던 환자군 9명을 제외하고 전체 32명의 자료를 분석하였다. 망간 축적에 관련된 객관적 지표로서 T1 강조 MRI에서 나타나는 담창구 부위의 고신호강도를 전두부 백색질 신호강도로 나눈 수에 100을 곱하여 구한 PI를 택하였다. 환자군과 대조군 사이의 PI와 망간농도들의 평균을 비교하였다. 여러 변수들과 PI와의 상관성을 보기 위해서는 상관분석을 시행하였다. 결과 : 간장 질환자 22명 가운데 18명(81.8%)에서 뇌 MRI 상 고신호강도가 나타났다. 대조군 10명에서는 아무도 MRI 소견상 고신호강도가 나타나지 않았다. 간장 질환자에서의 평균 PI는 122.62로 대조군의 106.23보다 유의하게 높게 나타났다(p<0.01). 간장 질환자의 전혈에서 망간농도는 2.34㎍/㎗으로 대조군의 1.44㎍/㎗와 비교하여 유의하게 높게 나타났다(p<0.05). 혈장과 소변 내 망간농도는 대조군에서 다소 높게 나타났으나, 통계적으로 유의하지는 않았다. 또한 혈색소, 빌리루빈, AST가 대조군과 환자군 사이에서 유의한 차이가 있었다(p<0.05). 전혈(p=0.489, P<0.01, n=29)과 적혈구(p=0.573, P<0.01, n=22) 내 망간농도와 PI 사이에는 각각 유의한 상관관계가 있었다. 그러나 혈장과 소변 내 망간 농도와 PI와의 상관관계는 통계적으로 유의하지 않았다. 총빌리루빈 또한 PI와 유의한 상관관계를 나타내었다(p=0.509, P<0.01, n=32). 결론 : 전혈 또는 적혈구 내의 망간 농도가 뇌 내 망간 침착으로 인한 T1 강조 MRI상 담창구 부위의 고신호 강도를 잘 반영하는 유용한 지표이다. Objectives: The objectives of this study were to clarify which biological manganese exposure indices reflect the pallidal signal intensities in magnetic resonance imaging (MRI) in liver cirrhotics. Methods: We examined whole blood, plasma, RBC and urinary manganese concentrations, as well as, brain MRI in 22 cirrhotic patients and 10 healthy controls. From MRI scans we calculated the signal intensity of the globus pallidus using the pallidal index (PI), the ratio of the globus pallidus to subcortical frontal white-matter signal intensity in axial T1 -weighted MRl planes multiplied by 100. In addition, we studied the relationships between PI and other measurements. Results: The high signal intensity in the globus pallidus on T1-weighted MRI was observed in 18 (81.8%) patients. There was a significant correlation between whole blood and RBC manganese concentration, and PI on MRI. According to multiple linear regression, whole blood and RBC manganese concentration reflected PI on MRI better the other indices did. Conclusions: Whole blood and RBC manganese concentrations could be useful as biological manganese exposure indices that reflect PI on MRI.

Isolation and Characterization of a Novel Lipase from a Metagenomic Library of Tidal Flat Sediments: Evidence for a New Family of Bacterial Lipases

Lee, Mi-Hwa,Lee, Choong-Hwan,Oh, Tae-Kwang,Song, Jae Kwang,Yoon, Jung-Hoon American Society for Microbiology 2006 Applied and environmental microbiology Vol.72 No.11

<B>ABSTRACT</B><P>We cloned <I>lipG</I>, which encoded a lipolytic enzyme, from a Korean tidal flat metagenomic library. LipG was related to six putative lipases previously identified only in bacterial genome sequences. These enzymes comprise a new family. We partially characterized LipG, providing the first experimental data for a member of this family.</P>

An Evaluation of the Effects of Rehabilitation Practiced in Coal Mining Spoils in Korea: 2. An Evaluation Based on the Physicochemical Properties of Soil

Lee, Chang-Seok*,Yong-Chan Cho,Hyun-Chul Shin,Seon-Mi Lee,Woo-Seok Oh,Sung-Ae Park,Eun Sil Seol,Choong-Hwa Lee,Ahn-Heum Eom,조현제 한국생태학회 2008 Journal of Ecology and Environment Vol.31 No.1

The effectiveness of rehabilitation programs for coal mining spoils in Samcheok, Jeongsun, and Mungyung were evaluated based on the physicochemical properties of soil in the rehabilitated areas. These spoils were reclaimed by introducing plants such as black locust (Robinia pseudoacacia), pitch pine (Pinus rigida), birch (Betula platyphylla var. japonica), alder (Alnus hirsuta), bush clover (Lespedeza cyrtobotrya), and grass (Lolium perenne) in planting beds covered with forest soil. In the surface soil, the pH, organic matter, total N, available P, and exchangeable Ca showed significant changes over the years after reclamation. The pH and exchangeable Ca content decreased exponentially over time, whereas organic matter increased linearly and total N and available P increased exponentially. Changes in the physicochemical properties of subsurface soils displayed a different pattern. There were significant changes over time in the organic matter, available P, and exchangeable Ca and Mg contents of the soil. Organic matter increased logarithmically with years since rehabilitation and available P increased exponentially. Meanwhile, exchangeable Ca decreased exponentially, and Mg decreased logarithmically. The changes in the subsurface soil were not as dramatic as those in the surface soil. This result suggests that the ameliorating effects of the establishment and growth of plants more pronounced on the surface soil layer. Stand ordination data showed different relationships with time since rehabilitation in the early and later stages of the rehabilitation process. In the early stages of rehabilitation, stands tended to be arranged in the order of reclamation age. However, in the later stages, there was not a clear relationship between reclamation age and vegetation characteristics. This result suggests that soil amelioration is required for the early stages, after which an autogenic effect becomes more prominent as the vegetation becomes better established.

Assessment of General and Cardiac Toxicities of Astemizole in Male Cynomolgus Monkeys: Serum Biochemistry and Action Potential Duration

Lee, Jong-Hwa,Kim, Do-Geun,Seo, Joung-Wook,Lee, Hyang-Ae,Oh, Jeong-Hwa,Shin, Ho-Chul,Yoon, Seok-Joo,Kim, Choong-Yong Korean Society of ToxicologyKorea Environmental Mu 2008 Toxicological Research Vol.25 No.2

Toxicology screening following treatment with astemizole, a histamine receptor antagonist, at oral doses of 0, 10, 30 and 60 mg/kg was carried out in male cynomolgus monkeys (Macaca fascicularis). No dose-related changes in mortality, clinical signs, body weight changes, food consumption, or urine analysis occurred in any animal compared to the vehicle control. However, the high-dose group showed a decrease in BUN and ALP compared to vehicle control group. In addition, the levels of TG, AST, ALP and CK increased. Although astemizole did not produce significant toxicological changes at any dose tested, we predict that it can cause toxicological changes of the liver and heart based on the changes in the serum parameters related to the heart and liver. The Action Potential Duration (APD) was prolonged in the heart of 60 mg/kg treatment group compared to the control group. The APD increase in 60 mg/kg treatment group along the other related changes in toxicological parameters imply that astemizole has major cardiotoxic effects in the cynomolgus monkey. This study is a valuable assessment for predicting the general toxicity and cardiotoxic effects of antihistamine drugs using nonhuman primates.

An Evaluation of the Effects of Rehabilitation Practiced in the Coal Mining Spoils in Korea 1. An Evaluation Based on Vegetation

Lee, Chang-Seok,Cho, Yong-Chan,Shin, Hyun-Chul,Lee, Seon-Mi,Lee, Choong-Hwa,Eom, Ahn-Heum The Ecological Society of Korea 2007 Journal of Ecology and Environment Vol.30 No.1

This study evaluated the effects of rehabilitation of existing coal mining spoils on species composition and species diversity. The species composition of most rehabilitated stands differed from that of the reference stands, and thus did not suggest successful rehabilitation. However, stands subjected to restorative treatment many years ago showed higher species diversity than the reference stands and thereby met the goals of rehabilitation. Our results demonstrate that restorative treatments practiced in the past created a heterogeneous ecological space with regard to the surrounding areas. Therefore, even though species diversity increased several years after rehabilitation, this does not indicate that the treatment achieved true rehabilitation success. The treatment did result in temporary stability through increased species diversity, but it could not be described as successful rehabilitation in terms of biological integrity with the surrounding ecosystems.

QUANTIFICATION OF ZABOFLOXACIN IN RAT PLASMA USING HPLC-UV DETECTOR AND ITS APPLICATION TO A PHARMACOKINETIC STUDY

Lee, Jong-Hwa,Ha, Jung-Heun,Park, Dae-Hun,Choi, Dong-Rack,Lee, Gye-Won,Ahn, Sung-Hoon,Kim, Choong-Yong Marcel Dekker 2014 JOURNAL OF LIQUID CHROMATOGRAPHY AND RELATED TECHN Vol.37 No.3