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- 저자 : Chin-Cheng Lin (검색결과 34 건)
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Chin-Cheng Lin,Pin-Chi Tang,Hsin-I Chiang 한국식품과학회 2019 Food Science and Biotechnology Vol.28 No.6
Incidents of food fraud have occurred worldwide,particularly in the form of meat adulteration. In thisstudy, molecular probes were developed using the Randomamplification of polymorphic DNA (RAPD) polymerasechain reaction (PCR) technique in order to identify threebeef subspecies–Holstein, Angus, and Taiwan YellowCattle. Four RAPD-PCR 10-nucleotide primers were chosenout of a total of 60 primers. The selection was based onthe reproducibility of species-specific amplicons able todetect various origins of cattle breeds. The resultsdemonstrated that primer OPK12 produced three uniqueamplicons (1100 bp, 1000 bp and 480 bp) in Holstein;primer OPK14 generated one amplicon that only appearedin Holstein and Angus (200 bp); primer OPK19 amplifiedtwo species-specific amplicons in Holstein measuring550 bp and 650 bp, respectively. However, due to therelatively lower repeatability of RAPD-PCR, higher andmore specific testing repeats were required to increase theaccuracy of the conclusion.
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Angel Chao,Yi-Hao Lin,Lan-Yan Yang,Ren-Chin Wu,Wei-Yang Chang,Pi-Yueh Chang,Shih-Cheng Chang,Chiao-Yun Lin,Huei-Jean Huang,Cheng-Tao Lin,Hung-Hsueh Chou,Kuan-Gen Huang,Wen-Ling Kuo,Ting-Chang Chang,Ch 대한부인종양학회 2020 Journal of Gynecologic Oncology Vol.31 No.3
Objective: The characteristics of patients with metachronous breast and ovarian malignancies and the pathogenic role of BRCA1/2 mutations remain poorly understood. We investigated these issues through a review of hospital records and nationwide Taiwanese registry data, followed by BRCA1/2 mutation analysis in hospital-based cases. Methods: We retrospectively retrieved consecutive clinical records of Taiwanese patients who presented with these malignancies to our hospital between 2001 and 2017. We also collected information from the Data Science Center of the Taiwan Cancer Registry (TCR) between 2007 and 2015. Next-generation sequencing and multiplex ligation-dependent probe amplification were used to identify BRCA1/2 mutations and large genomic rearrangements, respectively. When BRCA1/2 mutations were identified in index cases, pedigrees were reconstructed and genetic testing was offered to family members. Results: A total of 12,769 patients with breast cancer and 1,537 with ovarian cancer were retrieved from our hospital records. Of them, 28 had metachronous breast and ovarian malignancies. We also identified 113 cases from the TCR dataset. Eighteen hospital-based cases underwent BRCA1/2 sequencing and germline pathogenic mutations were detected in 7 patients (38.9%, 5 in BRCA1 and 2 in BRCA2). All BRCA1/2 mutation carriers had ovarian high-grade serous carcinomas. Of the 12 patients who were alive at the time of analysis, 5 were BRCA1/2 mutation carriers. All of them had family members with BRCA1/2-associated malignancies. Conclusions: Our results provide pilot evidence that BRCA1/2 mutations are common in Taiwanese patients with metachronous breast and ovarian malignancies, supporting the clinical utility of genetic counseling.
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Lin, Chin-Tsai,Chang, Che-Wei,Wu, Cheng-Ru,Chen, Huang-Chu The Korean Society for Quality Management 2006 The Asian Journal on Quality Vol.7 No.2
This study describes a novel algorithm for optimizing the quality yield of silicon wafer slicing. 12 inch wafer slicing is the most difficult in terms of semiconductor manufacturing yield. As silicon wafer slicing directly impacts production costs, semiconductor manufacturers are especially concerned with increasing and maintaining the yield, as well as identifying why yields decline. The criteria for establishing the proposed algorithm are derived from a literature review and interviews with a group of experts in semiconductor manufacturing. The modified Delphi method is then adopted to analyze those results. The proposed algorithm also incorporates the analytic hierarchy process (AHP) to determine the weights of evaluation. Additionally, the proposed algorithm can select the evaluation outcomes to identify the worst machine of precision. Finally, results of the exponential weighted moving average (EWMA) control chart demonstrate the feasibility of the proposed AHP-based algorithm in effectively selecting the evaluation outcomes and evaluating the precision of the worst performing machines. So, through collect data (the quality and quantity) to judge the result by AHP, it is the key to help the engineer can find out the manufacturing process yield quickly effectively.
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Chin-Fa Hwang,Jen-Han Chang,Jer-Yiing Houng,Cheng-Chih Tsai,Chien-Ku Lin,Hau-Yang Tsen 한국생물공학회 2012 Biotechnology and Bioprocess Engineering Vol.17 No.4
An immune-enhancing strain, Lactobacillus plantarum Pi06, isolated from a healthy infant was used for biomass production following optimization of the medium in shake-flask culture. Preliminary studies showed that commercial MRS medium and cultivation under static conditions generated higher biomass production than four other tested media with or without a shaking condition. The selected medium composition, consisting of glucose,yeast extract, soy peptone, ammonium citrate, and corn steep liquor, was further optimized using a systematic method that integrated the Taguchi array design and the Box–Behnken method. The response effects of these factors were first investigated using Taguchi design under an L16 (45) array. The suggested medium composition,derived from Statistica 7.1 using the Taguchi design, was applied to cultivate cells and a biomass of 7.16 g dry cell weight (DCW)/L was obtained. Response surface methodology based on the Box–Behnken method for the three response variables of glucose, yeast extract, and corn steep liquor was then used to further increase the biomass level to 8.94 g DCW/L. The resulting optimum medium consisted of 35 g/L glucose, 35 g/L yeast extract, and 40 mL/L corn steep liquor. Compared with the initial medium, the biomass yield was improved from 4.31 to 8.94 g DCW/L, an enhancement of approximately 107%.
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Seismic performance of a rocking bridge pier substructure with frictional hinge dampers
Chin-Tung Cheng,Fu-Lin Chen 국제구조공학회 2014 Smart Structures and Systems, An International Jou Vol.14 No.4
The rocking pier system (RPS) allows the columns to rock on beam or foundation surfacesduring the attacks of a strong earthquake. Literatures have proved that seismic energy dissipated by the RPSthrough the column impact is limited. To enhance the energy dissipation capacity of a RPS bridgesubstructure, frictional hinge dampers (FHDs) were installed and evaluated by shaking table tests. Thesupplemental FHDs consist of two brass plates sandwiched by three steel plates. The strategy ofself-centering design is to isolate the seismic energy by RPS at the columns and then dissipate the energy byFHDs at the bridge deck. Component tests of FHD were first conducted to verify the friction coefficient anddynamic characteristic of the FHDs. In total, 32 shaking table tests were conducted to investigate parameterssuch as wave forms of the earthquake (El Centro 1940 and Kobe 1995) and normal forces applied on thefriction dampers. An analytical model was also proposed to compare with the tested damping of the bridgesub-structure with or without FHDs.
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Seismic performance of a rocking bridge pier substructure with frictional hinge dampers
Cheng, Chin-Tung,Chen, Fu-Lin Techno-Press 2014 Smart Structures and Systems, An International Jou Vol.14 No.4
The rocking pier system (RPS) allows the columns to rock on beam or foundation surfaces during the attacks of a strong earthquake. Literatures have proved that seismic energy dissipated by the RPS through the column impact is limited. To enhance the energy dissipation capacity of a RPS bridge substructure, frictional hinge dampers (FHDs) were installed and evaluated by shaking table tests. The supplemental FHDs consist of two brass plates sandwiched by three steel plates. The strategy of self-centering design is to isolate the seismic energy by RPS at the columns and then dissipate the energy by FHDs at the bridge deck. Component tests of FHD were first conducted to verify the friction coefficient and dynamic characteristic of the FHDs. In total, 32 shaking table tests were conducted to investigate parameters such as wave forms of the earthquake (El Centro 1940 and Kobe 1995) and normal forces applied on the friction dampers. An analytical model was also proposed to compare with the tested damping of the bridge sub-structure with or without FHDs.
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Constructions and Properties of General (k, n) Block-Based Progressive Visual Cryptography
Chih Cheng Wu,Yi-Chin Lin,김천식 한국전자통신연구원 2015 ETRI Journal Vol.37 No.5
Recently, Hou and others introduced a (2, n) block-based progressive visual cryptographic scheme (BPVCS) in which image blocks can be gradually recovered step by step. In Hou and others’ (2, n)-BPVCS, a secret image is subdivided into n non-overlapping image blocks. When t (2 ≤ t ≤ n) participants stack their shadow images, all the image blocks associated with these t participants will be recovered. However, Hou and others’ scheme is only a simple 2-out-of-n) case. In this paper, we discuss a general (k, n)-BPVCS for any k and n. Our main contribution is to give two constructions (Construction 1 and Construction 2) of this general (k, n)-BPVCS. Also, we theoretically prove that both constructions satisfy a threshold property and progressive recovery of the proposed (k, n)-BPVCS. For k = 2, Construction 1 is reduced to Hou and others’ (2, n)-BPVCS.
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Su, Chin-Hui,Cheng, Chih-Hsiang,Lin, Jung-Hsin,Liu, Hsiu-Chou,Yu, Yen-Ting,Lin, Chai-Ching,Chen, Wei-Jung Asian Australasian Association of Animal Productio 2021 Animal Bioscience Vol.34 No.11
Objective: The objective of this experiment was to investigate the effects of different colors produced by light emitting diode (LED) on Brown Tsaiya ducks. Methods: A total of 144 female Brown Tsaiya ducks were randomly allocated into three individual cage rearing chambers with different LED illumination colors as treatments. Three different treatments were: i) white color, ii) blue color, and iii) red color. The experiment periods were from ducks 21 to 49 weeks of age, determined traits included i) egg laying performance, ii) feed intake, iii) egg shell breaking strength, iv) egg shell thickness, v) egg Haugh unit, vi) egg weight, vii) serum Estradiol and Progesterone concentration, and viii) behavior pattern. Results: The results indicated that when compared with white and blue color, red color could stimulate ducks sexual maturation and raised the egg laying performance. The red light group was also observed to have the highest feed intake among three treatments. The blue treatment had the lowest egg shell breaking strength and the highest egg weight among three treatments, nevertheless, no significant difference was observed among three treatments on egg shell thickness and egg Haugh unit. The red light group had higher serum estradiol concentration than the white and blue groups, but no significant difference among treatments on the serum Progesterone concentration was found. The results of behavior pattern indicated that red light group showed more feeding and less resting behavior compared to the blue light group. Conclusion: We found a potential of applying red light illumination in the indoor laying duck raising system with positive results on egg laying performance and acceptable egg weight, equivalent egg qualities compared to white and blue light.
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