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- 저자 : Chenxu Li (검색결과 14 건)
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Yarong Li,Yaqian Zhou,Huanjin Liu,Chenxu Wei,Shuli Chen,Zhengying Hua,Yan Xu,Yu Wu,Weidong Li 한국식품영양과학회 2022 Journal of medicinal food Vol.25 No.10
We investigated the changes in the main active ingredients and pharmacodynamic differences in the therapeutic effect of garlic before and after steaming and the correlation between them. The main active ingredients in raw garlic products (RGPs) and steamed garlic products (SGPs) were determined by high-pressure liquid chromatography and ultraviolet spectroscopy. Acute rapid diarrhea (AD) and antibiotic-induced diarrhea (DD) models were established in rats, and each group was treated with RGP and SGP, respectively. The main chemical components of garlic changed before and after steaming. Garlicin and alliinase were only found in RGP, whereas only alliin was found in SGP. Both RGP and SGP contained garlic polysaccharides. For in vivo experiments on AD, the average rate of loose stools was 100.00 ± 0.00, 31.55 ± 11.76, and 19.14 ± 6.62 in the RGP high-dose and SGP high-dose treatment groups, respectively; in DD, the rates were 91.11 ± 14.40, 19.33 ± 3.63, and 30.56 ± 4.30, respectively (P < .01, treatment vs. model groups). In AD, the average grade of loose stools was 2.33 ± 0.52 and 1.83 ± 0.75 in the model and RGP high-dose treatment groups, respectively (P < .05); in DD, the values were 2.17 ± 0.41 in the model group and 1.67 ± 0.52 in the SGP high-dose treatment group (P < .05). RGP had a better therapeutic effect on AD, mainly related to the antibacterial effect of garlicin in RGP. SGP had a better therapeutic effect on DD, mainly related to the alliin and garlic polysaccharide in SGP. This study could provide evidence to support the clinical use of garlic.
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Chenxu Zhang,Jia Huang,Xi Li,Chao Zhang 한국섬유공학회 2020 Fibers and polymers Vol.21 No.12
Carbon fiber-reinforced composite materials are widely employed in aircraft structures due to their high specificstrength and high specific modulus. However, the poor impact resistance of carbon fiber reinforced composites createschallenges for aircraft design and maintenance. The introduction of a layer of glass fibers in the hybrid composites caneffectively improve the impact performance of the composite laminate. In this work, finite element models for low-velocityimpact of carbon fiber laminate and glass fiber laminate are established and validated. A VUMAT subroutine in Abaqus isimplemented to evaluate the progressive damage of the composite materials, and a cohesive-zone model is employed tosimulate the interface failure behavior. The impact resistance of hybrid composite laminates is systematically studied basedon the results of the finite element simulation. Ten different hybrid configurations are studied and compared with a compositelaminate having a single type of fiber reinforcement. The numerical results for the global mechanical response, damagemodes and characteristics are extracted and systematically discussed. The results suggest that laminates having carbon fiberlayers on the top and bottom surfaces with glass fiber layers between them perform the best in terms of energy absorption. When the glass fiber layers are used for the top and bottom surfaces with carbon fiber layers as the core, the presence of acarbon fiber layer with a ±45 ° orientation can help to reduce the damage area.
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Yaqi Suo,Shenggang Fan,Chenxu Li,Shaoru Zeng,Chengliang Liu 한국강구조학회 2020 International Journal of Steel Structures Vol.20 No.6
Parametric analysis on the hysteresis performance of the low yield point steel plate sheer wall (LYP SPSW) with three different stiff ening confi gurations, including unstiff ened, cross stiff ened and diagonal stiff ened, was conducted using the fi nite element models which have been verifi ed by the test results. The parameters which have eff ects on the hysteretic behavior of LYP SPSW include ratio of height-to-thickness, stiff ness ratio of stiff ener, and the stiff ness ratio of the edge member. The hysteretic curves, skeleton curves and viscous damping coeffi cient-displacement curves of SPSW with diff erent stiff ening confi gurations were obtained. According to the numerical results, it can be seen that the shear resistance and hysteretic performance of LYP SPSW decrease with the increase of the ratio of height-to-thickness. The energy dissipation capacity and shear capacity of LYP SPSW can be improved eff ectively by setting cross and diagonal stiff eners, but when the stiff - ness ratio of stiff ener is greater than 10, the increase is no longer obvious. Furthermore, for steel plate shear walls without edge members, the diagonal cross-stiff ening steel shear wall can achieve better energy consumption. For steel plate shear walls with edge members, when the ratio of height-to-thickness is less than 100, a better energy dissipation can be achieved by using cross stiff ened steel plates; when the ratio of height-to-thickness is greater than or equal to 200, a better energy dissipation can be refl ected by adopting cross stiff ened steel plates. Finally, a restoring force model of the LYP SPSW with two-side connections is proposed.
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Direct Strength Method for Stainless Steel Lipped Channel Columns Undergoing Local Buckling
Meihe Chen,Shenggang Fan,Chenxu Li,Shaoru Zeng 한국강구조학회 2020 International Journal of Steel Structures Vol.20 No.6
This paper reports the results of a numerical investigation on the influence of local buckling on the ultimate strength and design of locally fixed-end and globally pined-end stainless steel lipped channel columns in compression. The elastic buckling load is a key parameter in predicting the design strength of stainless steel lipped channel columns. Elastic buckling loads under simple–simple, clamped–clamped and experimental boundary conditions have been compared. To extend the data, a finite element model of stainless steel lipped channel columns has been developed and verified against the test data. Parametric studies on the stainless steel lipped channel columns were performed. The test results are compared with the strength predictions from direct strength method (DSM), indicating that DSM included in North American specification is unsafe, but the DSM proposed by Becque et al. is conservative. A modified DSM equation was proposed and has been proven to accurately predict the ultimate capacities of the stainless steel lipped channel columns in compression
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Wei Peng,Jie Liu,Wei Peng,Chenxu Li,Fuxing Zong,Wensi Xu,Xing Zhang 한국화학공학회 2018 Korean Journal of Chemical Engineering Vol.35 No.8
Heterogeneous catalysts with low cost, environmentally friendly, highly effective and ready separation from aqueous solution are highly desirable. Magnetic CuO-Fe3O4 nanoparticles, a type of non-toxic bimetallic transition metal oxide, is a promising heterogeneous catalyst for activation of peroxymonosulfate (PMS) to generate reactive oxygen species (ROS) that has not been previously investigated. In this study, the activation of PMS by CuO-Fe3O4 nanoparticles was evaluated using the degradation of 4-chlorophenol as a model reaction. Several critical factors such as pH, catalyst dosage and PMS concentration were investigated. CuO-Fe3O4/PMS system demonstrated a wide effective pH range to degrade 4-chlorophenol, namely 5.5 to 9.5. With the increase of the catalyst dosage, the degradation efficiency of 4-chlorophenol appeared to increase first and then decrease, that the inflection point was 0.5 g/L. Elevated PMS concentration obviously improved the decomposition of 4-chlorophenol; however, the plateau was reached when the PMS concentration was 8mM. Further increase in PMS concentration would not significantly improve the removal efficiency. Through examining the effects of scavengers and electron spin resonance (ESR) analyses, CuO-Fe3O4 nanoparticles were proven to activate PMS through a non-radical and radical pathway to generate singlet oxygen, sulfate radicals and hydroxyl radicals. Based on results, CuO-Fe3O4 nanoparticles were effective, environmentally friendly and low cost catalysts for efficient activation of PMS. These features make CuO-Fe3O4 nanoparticles a readily available heterogeneous catalyst to activate PMS for refractory organic pollutants degradation in advanced oxidation processes (AOPs).
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Shenggang Fan,Runmin Ding,Shaoru Zeng,Chenxu Li,Chengliang Liu 한국강구조학회 2020 International Journal of Steel Structures Vol.20 No.6
The steel plate shear wall (SPSW) with two-side connections can be arranged fl exibly in the structure, and has no additional infl uence on the column, but its buckling capacity is diffi cult to be deduced directly by thin plate theory. The low yield point SPSW (LYP-SPSW) with two-side connections is proposed in this paper, including unstiff ened LYP-SPSW, cross-stiff ened LYP-SPSW and diagonally-stiff ened LYP-SPSW. The elastic buckling performance and buckling capacity of these three types of LYP-SPSWs are studied by numerical simulation. On the basis of the accurate model, a series of parametric analysis on the key factors were conducted, including the height-to-thickness ratio, the stiff ness ratio of the stiff ener, and the stiff ness ratio of the edge member, which have eff ects on the elastic buckling stress of the LYP-SPSW with two-side connections. The elastic buckling stress of the SPSW can be eff ectively increased by adding stiff eners and edge members, but it is unnecessary to use oversized stiff eners and edge members. Based on a large amount of parametric analysis, simplifi ed formulas for calculating the elastic buckling stresses of the three types of LYP-SPSWs mentioned above are proposed in this paper.
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Shaowei Lu,Yaoyao Bai,Jijie Wang,Chenxu Zhao,Wei Li,Xiaoqiang Wang,Zhenwei Huang 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2018 NANO Vol.13 No.6
Ultrathin multi-walled carbon nanotubes (MWCNTs) buckypapers inserted with Mn nanopowder were fabricated via vacuum filtration method, at a lower manufacturing cost and easier operation. The buckypapers were characterized structurally using scanning electron microscopy, energy-dispersive spectrometer and X-ray diffraction. Electromagnetic interference (EMI) shielding effectiveness (SE) of MWCNTs buckypapers inserted with Mn nanopowder (0–30 wt.%) were tested in X-band (8.2–12.4 GHz). When the blended Mn nanopowder content is 20 wt.%, the buckypaper exhibits much higher EMI SE of average value up to 42 dB with the thickness of only 0.11 mm. Further, this buckypaper is flexible and lightweight, and can be integrated with resin matrix composites. Thus, the results and techniques promise a simple and effective approach to achieve lightweight and ultrathin composite films for a wide application prospect in the field of EMI shielding and microwave absorption.
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Research on Local Buckling of Stainless Steel Lipped C-Section Beam Around Strong-Axis
Shenggang Fan,Hang Zhou,Zhixia Ding,Chenxu Li,Qinglin Jiang 한국강구조학회 2022 International Journal of Steel Structures Vol.22 No.5
To study the local buckling capacity of stainless steel beams with lipped C-sections under strong axis bending, tensile tests were performed on 12 stainless steel coupons based on S30408 austenitic stainless steel (AISI304) in fl at and corner areas, and mechanical properties and stress–strain curves were obtained. Then, local buckling capacity tests were performed on 6 specimens of stainless steel beams under strong axis bending to determine their mechanical properties and failure mechanism. The failure phenomenon, load–displacement curve, load–strain curve and local buckling capacity were determined. Results show that the failure modes of the specimens are local buckling failure of the fl ange and web at mid-span. Additionally, a refi ned fi nite element analysis model was developed using Python and ABAQUS to simulate and analyse the mechanical performance and local buckling capacity. Then, the analytical results were compared to the test results, and the accuracy of the refi ned model was verifi ed. Then, the refi ned model of the stainless steel C-section beam was simplifi ed including the constraint simplifi cation model, which considered diff erent fl ange constraints and initial imperfections, and the length simplifi cation model, which was based on diff erent length and support constraints. The comparative analysis results showed that the constraint simplifi cation model can simulate the local buckling failure mode more accurately than other models. Additionally, initial imperfections were shown to have little eff ect on the local buckling capacity; however, specimen length and the bearing constraint condition did aff ect the local buckling capacity.
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Huang, Qingxia,Lou, Tingting,Lu, Jing,Wang, Manying,Chen, Xuenan,Xue, Linyuan,Tang, Xiaolei,Qi, Wenxiu,Zhang, Zepeng,Su, Hang,Jin, Wenqi,Jing, Chenxu,Zhao, Daqing,Sun, Liwei,Li, Xiangyan The Korean Society of Ginseng 2022 Journal of Ginseng Research Vol.46 No.6
Background: Aerobic cellular respiration provides chemical energy, adenosine triphosphate (ATP), to maintain multiple cellular functions. Sirtuin 1 (SIRT1) can deacetylate peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PGC-1α) to promote mitochondrial biosynthesis. Targeting energy metabolism is a potential strategy for the prevention and treatment of various diseases, such as cardiac and neurological disorders. Ginsenosides, one of the major bioactive constituents of Panax ginseng, have been extensively used due to their diverse beneficial effects on healthy subjects and patients with different diseases. However, the underlying molecular mechanisms of total ginsenosides (GS) on energy metabolism remain unclear. Methods: In this study, oxygen consumption rate, ATP production, mitochondrial biosynthesis, glucose metabolism, and SIRT1-PGC-1α pathways in untreated and GS-treated different cells, fly, and mouse models were investigated. Results: GS pretreatment enhanced mitochondrial respiration capacity and ATP production in aerobic respiration-dominated cardiomyocytes and neurons, and promoted tricarboxylic acid metabolism in cardiomyocytes. Moreover, GS clearly enhanced NAD<sup>+</sup>-dependent SIRT1 activation to increase mitochondrial biosynthesis in cardiomyocytes and neurons, which was completely abrogated by nicotinamide. Importantly, ginsenoside monomers, such as Rg1, Re, Rf, Rb1, Rc, Rh1, Rb2, and Rb3, were found to activate SIRT1 and promote energy metabolism. Conclusion: This study may provide new insights into the extensive application of ginseng for cardiac and neurological protection in healthy subjects and patients.
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