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Wang, H.Y.,Chang, H.,Xu, W.,Chang, G.B.,Lu, S.X.,Du, L.,Sun, W.,Xu, M.,Wang, Q.H. Asian Australasian Association of Animal Productio 2003 Animal Bioscience Vol.16 No.2
This paper makes an analysis of the ecological behaviours of 3 categories of quails, namely wild Japanese quails from the Weishan Lake Area, medium-sized domestic quails and pint-sized domestic quails. The study indicates as follows: (1) There is difference in morphological and biological habits between domestic quails and wild Japanese ones. (2) The cross-breeding between the wild and domestic quails is a cross from exclusion to affinity. (3) The behaviours of quails such as pursuit,paw and mating are selective. (4) The wild Japanese quails and domestic ones can succeed in mating and in reproducing fertilized eggs but with a low rate. (5) Evolutionary differentiation has been formed in varying degrees between the domestic quails and their wild ancestors in morphological and ecological characteristics.
Wang Lu,Dai Ying-Jie,Cui Yu,Zhang Hong,Jiang Chang-Hao,Duan Ying-Jie,Zhao Yong,Feng Ye-Fang,Geng Shi-Mei,Zhang Zai-Hui,Lu Jiang,Zhang Ping,Zhao Li-Wei,Zhao Hang,Ma Yu-Tong,Song Cheng-Guang,Zhang Yi,Ch 대한뇌졸중학회 2023 Journal of stroke Vol.25 No.3
Background and Purpose Intravenous tenecteplase (TNK) efficacy has not been well demonstrated in acute ischemic stroke (AIS) beyond 4.5 hours after onset. This study aimed to determine the effect of intravenous TNK for AIS within 4.5 to 24 hours of onset. Methods In this pilot trial, eligible AIS patients with diffusion-weighted imaging (DWI)-fluid attenuated inversion recovery (FLAIR) mismatch were randomly allocated to intravenous TNK (0.25 mg/kg) or standard care within 4.5–24 hours of onset. The primary endpoint was excellent functional outcome at 90 days (modified Rankin Scale [mRS] score of 0–1). The primary safety endpoint was symptomatic intracranial hemorrhage (sICH). Results Of the randomly assigned 80 patients, the primary endpoint occurred in 52.5% (21/40) of TNK group and 50.0% (20/40) of control group, with no significant difference (unadjusted odds ratio, 1.11; 95% confidence interval 0.46–2.66; <i>P</i>=0.82). More early neurological improvement occurred in TNK group than in control group (11 vs. 3, <i>P</i>=0.03), but no significant differences were found in other secondary endpoints, such as mRS 0–2 at 90 days, shift analysis of mRS at 90 days, and change in National Institutes of Health Stroke Scale score at 24 hours and 7 days. There were no cases of sICH in this trial; however, asymptomatic intracranial hemorrhage occurred in 3 of the 40 patients (7.5%) in the TNK group. Conclusion This phase 2, randomized, multicenter study suggests that intravenous TNK within 4.5–24 hours of onset may be safe and feasible in AIS patients with a DWI-FLAIR mismatch.
Load Sharing Performance of Herringbone Planetary Gear System with Flexible Pin
Chang-lu Wang,Jing Wei,Zi-heng Wu,Long Lu,Hao Gao 한국정밀공학회 2019 International Journal of Precision Engineering and Vol.20 No.12
To study the load distribution mechanism of the power-split transmission, and improve the carrying capacity of the herringbone star gear transmission system, the dynamic model of the planetary gear system for a geared turbofan engine with the flexible pin was established based on the node finite element method. The model considered the comprehensive influence of meshing error, time-varying meshing stiffness, bearing supporting stiffness and meshing phase. The dynamic load sharing performance of the system were studied in the equivalent meshing error, and the influence of the error incentives and structure of pins on the load sharing characteristics was analyzed. The results indicate that the vibration track of the center gears deviates from the origin because of the eccentricity error. The load sharing performance of the system can be improved by improving gears’ manufacturing precision. Moreover, the influence of manufacturing errors is larger than that of assembling errors. The flexible pin improved by Montestruc has the best load sharing performance among the four types of pin models designed in the study. The load sharing performance declines with an increase of in input speed and a decrease in input power.
Ru-Band Lu,Yun-Hsuan Chang,Sheng-Yu Lee,Tzu-Yun Wang,Shu-Li Cheng,Po See Chen,Yen Kuang Yang,Jau-Shyong Hong,Shiou-Lan Chen 대한정신약물학회 2020 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.18 No.1
Objective: Valproic acid (VPA) is an anticonvulsant and commonly long term used as a mood stabilizer for patients with mood disorders. However its chronic effects on the hematological changes were noticed and need to be further evaluated. In this study, we evaluated, in Taiwanese Han Chinese patients with bipolar disorders (BD), the chronic effects of VPA or VPA plus dextromethorphan (DM) on the hematological molecules (white blood cell [WBCs], red blood cells [RBCs], hemoglobin, hematocrit, and platelets). Methods: In a 12-week, randomized, double-blind study, we randomly assigned BD patients to one of three groups: VPA plus either placebo (VPA+P, n = 57) or DM (30 mg/day, VPA+DM30, n = 56) or 60 mg/day (VPA+DM60, n = 53). The Young Mania Rating Scale and Hamilton Depression Rating Scale were used to evaluate symptom severity, and the hematological molecules were checked. Results: Paired t test showed that the WBC, neutrophils, platelets and RBCs were significantly lowered after 12 weeks of VPA+P or VPA+DM30 treatment. VPA+DM60 represented the protective effects in the WBCs, neutrophils, and RBCs but not in the platelets. We further calculated the changes of each hematological molecules after 12 weeks treatment. We found that combination use of DM60 significantly improved the decline in neutrophils induced by the long-term VPA treatment. Conclusion: Hematological molecule levels were lower after long-term treatment with VPA. VPA+DM60, which yielded the protective effect in hematological change, especially in the neutrophil counts. Thus, DM might be adjunct therapy for maintaining hematological molecules in VPA treatment.
NOx emission from incineration of organic liquid waste in a circulating fluidized bed
Chang-Sui Zhao,Hui-Chao Chen,Yong-wang Li,Duan-Feng Lu 한국화학공학회 2007 Korean Journal of Chemical Engineering Vol.24 No.5
incineration test of a toxic chemical organic waste liquid was conducted on a circulating fluidized bed(CFB) incinerator. The flue gas was measured online with the advanced SAE-19 flue gas analyzer. The effects of severalfactors, in terms of flow rate of waste liquid, ratio of waste liquid injected into dense bed of the CFB, excess air co-efficient, the secondary air fraction and bed temperature on NOx emissions, were verified. The experimental resultsthe excess air coefficient or the bed temperature and those decrease with increase in the ratio of waste liquid injectedinto the dense bed of the CFB or the secondary air fraction. During the test runs, NOx concentration in flue gas metthe national regulation on NOx emissions due to suppresive effect of low temperature and staged combustion in CFBon NOx formation.
Aggregation mechanism of fine fly ash particles in uniform magnetic field
Chang-Sui Zhao,Yong-Wang Li,Xin Wu,Duan-Feng Lu,Song Han 한국화학공학회 2007 Korean Journal of Chemical Engineering Vol.24 No.2
of fly ash particles with size range of 0.023-9.314m in a uniform magnetic field was inves-tigated for removing them. A binary collision-aggregation model evaluating particle aggregation coefficient was devel-oped. Based on the model, particle removal efficiency was calculated by solving the General Dynamic Equation. Thecomparison was done between the calculated and experimental data. The modeling aggregation coefficient shows thatthe aggregation coefficient increases with particle size, and the bigger the size difference between two particles is, thehigher than those of the smaller and bigger ones. The effect of the magnetic flux density on total particle removal effi-ciency is similar to that on aggregation coefficient. Before particles are saturatedly magnetized, their total removal effi-ciency increases with an increase in the magnetic flux density. Higher removal efficiency can also be caused by pro-longing the particle residence time in the magnetic field or increasing their mass concentration. The particle numbermedian diameter decreases with an increase in the total removal efficiency. Calculation results are found to coincideessentially with the experimental data.
Genetic Differentiation among Sheep Populations from Near-sea Mainland in East Asia
Lu, S.X.,Chang, H.,Du, L.,Tsunoda, K.,Ji, D.J.,Sun, W.,Yang, Z.P.,Chang, G.B.,Mao, Y.J.,Wang, Q.H.,Xu, M. Asian Australasian Association of Animal Productio 2004 Animal Bioscience Vol.17 No.10
Using the method of 'random sampling in typical colonies of the central area of the habitat', 60 Small-tailed Han sheep were obtained in Jining city, Shangdong province. The variations of Small-tailed Han sheep at 12 structural loci encoding blood proteins were detected by several electrophoresis techniques and their gene frequencies were then estimated. The same data of four other sheep populations from Near-sea Mainland in East Asia were cited for the analysis of genetic differentiation. The average heterozygosities of five populations, namely Kharkhorin sheep, Ulaanbaatar sheep, Small-tailed Han sheep, Hu sheep and Cham Tribe sheep were 0.3447, 0.3285, 0.3157, 0.3884 and 0.2300, respectively. The coefficient of gene differentiation among four populations, Kharkhorin sheep, Ulaanbaatar sheep, Small-tailed Han sheep and Hu sheep, was 0.045557, and that between these four breeds and Cham Tribe sheep was 0.088005, indicating that the level of gene differentiation among the former four sheep populations of Mongolian group was comparatively lower than that between Cham Tribe sheep and other four sheep populations. The origin of Cham Tribe sheep deserve further research. The documentary research on the evolution of Small-tailed Han sheep and Hu sheep from Mongolian sheep was further verified by the biochemical experiments in the study. It was reasonably deduced that Hu sheep, Small Tailed Han sheep and Cham Tribe sheep were decreasingly influenced by the bloodline of Mongolian sheep.
Potential Study Perspectives on Mechanisms and Correlations Between Adiposity and Malignancy
Lu, Kun,Song, Xiao-Lian,Han, Shi-Long,Wang, Chang-Hui,Zhong, Ni,Qi, Li-Feng Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.2
Adiposity is a well-recognized risk factor of type 2 diabetes and cardiovascular disease, and recently there is increasing evidence that excess body weight is an avoidable cause of cancer, including gastrointestinal, endometrial, esophageal adenocarcinoma, colorectal, postmenopausal breast, prostate, and renal malignancies. The mechanisms whereby adiposity is associated with tumor development remains not well understood. There are some most studied hypothesized mechanisms such as, high levels of insulin and free levels of insulin-like growth factors, sex hormones, adipocytokines, and inflammatory cytokines, adiposity-induced hypoxia, and so on. The potential mechanisms and conclusions in adiposity associated with increased risk for developing malignancy, and the underlying cellular and molecular mechanisms will be studied very well in the near future.