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- 저자 : Duan-Feng Lu (검색결과 5 건)
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Lei Lu,Gaston A. Fermandois,Xilin Lu,Billie F. Spencer, Jr.,Yuan-Feng Duan,Ying Zhou 국제구조공학회 2019 Smart Structures and Systems, An International Jou Vol.23 No.6
Cables are prone to vibration due to their low inherent damping characteristics. Recently, negative stiffness dampers have gained attentions, because of their promising energy dissipation ability. The viscous inertial mass damper (termed as VIMD hereinafter) can be viewed as one realization of the inerter. It is formed by paralleling an inertial mass part with a common energy dissipation element (e.g., viscous element) and able to provide pseudo-negative stiffness properties to flexible systems such as cables. A previous study examined the potential of IMD to enhance the damping of stay cables. Because there are already models for common energy dissipation elements, the key to establish a general model for IMD is to propose an analytical model of the rotary mass component. In this paper, the characteristics of the rotary mass and the proposed analytical model have been evaluated by the numerical and experimental tests. First, a series of harmonic tests are conducted to show the performance and properties of the IMD only having the rotary mass. Then, the mechanism of nonlinearities is analyzed, and an analytical model is introduced and validated by comparing with the experimental data. Finally, a real-time hybrid simulation test is conducted with a physical IMD specimen and cable numerical substructure under distributed sinusoidal excitation. The results show that the chosen model of the rotary mass part can provide better estimation on the damper’s performance, and it is better to use it to form a general analytical model of IMD. On the other hand, the simplified damper model is accurate for the preliminary simulation of the cable responses.
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Wang Lu,Dai Ying-Jie,Cui Yu,Zhang Hong,Jiang Chang-Hao,Duan Ying-Jie,Zhao Yong,Feng Ye-Fang,Geng Shi-Mei,Zhang Zai-Hui,Lu Jiang,Zhang Ping,Zhao Li-Wei,Zhao Hang,Ma Yu-Tong,Song Cheng-Guang,Zhang Yi,Ch 대한뇌졸중학회 2023 Journal of stroke Vol.25 No.3
Background and Purpose Intravenous tenecteplase (TNK) efficacy has not been well demonstrated in acute ischemic stroke (AIS) beyond 4.5 hours after onset. This study aimed to determine the effect of intravenous TNK for AIS within 4.5 to 24 hours of onset. Methods In this pilot trial, eligible AIS patients with diffusion-weighted imaging (DWI)-fluid attenuated inversion recovery (FLAIR) mismatch were randomly allocated to intravenous TNK (0.25 mg/kg) or standard care within 4.5–24 hours of onset. The primary endpoint was excellent functional outcome at 90 days (modified Rankin Scale [mRS] score of 0–1). The primary safety endpoint was symptomatic intracranial hemorrhage (sICH). Results Of the randomly assigned 80 patients, the primary endpoint occurred in 52.5% (21/40) of TNK group and 50.0% (20/40) of control group, with no significant difference (unadjusted odds ratio, 1.11; 95% confidence interval 0.46–2.66; <i>P</i>=0.82). More early neurological improvement occurred in TNK group than in control group (11 vs. 3, <i>P</i>=0.03), but no significant differences were found in other secondary endpoints, such as mRS 0–2 at 90 days, shift analysis of mRS at 90 days, and change in National Institutes of Health Stroke Scale score at 24 hours and 7 days. There were no cases of sICH in this trial; however, asymptomatic intracranial hemorrhage occurred in 3 of the 40 patients (7.5%) in the TNK group. Conclusion This phase 2, randomized, multicenter study suggests that intravenous TNK within 4.5–24 hours of onset may be safe and feasible in AIS patients with a DWI-FLAIR mismatch.
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Alu Tandem Sequences Inhibit GFP Gene Expression by Triggering Chromatin Wrapping
Xiu Fang Wang,Xiao Yan Wang,Jing Liu,Jing Jing Feng,Wen Li Mu,Xiao Juan Shi,Qin Qing Yang,Xiao Cui Duan,Ying Xie,Zhan Jun Lu 한국유전학회 2009 Genes & Genomics Vol.31 No.3
Alu elements belonging to the short interspersed nuclear elements (SINE) of repetitive elements are present in more than one million copies which altogether represent 10% of the whole human genome. In this study, the roles of Alu tandem sequences in the process of GFP gene (GFP) expression and packing into chromatin of its DNA were studied. To detect the effect of Alu repeats on gene expression, different copies of Alus were inserted GFP downstream respectively in pEGFP-C1 vector. We found that Alu sequences decreased the amount of GFP transcription, the percentage of GFP positive cells and the accessibility to DNase I in length-dependent manner. Inserting Alu caused the production of higher-molecular-mass RNA, indicating Alu sequence did not induce premature transcriptional termination. Tight packing chromatins keep silent and resist to DNase I digestion, which is a general phenomenon. We suggested that head and tail tandem Alu sequences suppressed GFP expression in length dependent manner by triggering chromatin packing.
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Aggregation mechanism of fine fly ash particles in uniform magnetic field
Chang-Sui Zhao,Yong-Wang Li,Xin Wu,Duan-Feng Lu,Song Han 한국화학공학회 2007 Korean Journal of Chemical Engineering Vol.24 No.2
of fly ash particles with size range of 0.023-9.314m in a uniform magnetic field was inves-tigated for removing them. A binary collision-aggregation model evaluating particle aggregation coefficient was devel-oped. Based on the model, particle removal efficiency was calculated by solving the General Dynamic Equation. Thecomparison was done between the calculated and experimental data. The modeling aggregation coefficient shows thatthe aggregation coefficient increases with particle size, and the bigger the size difference between two particles is, thehigher than those of the smaller and bigger ones. The effect of the magnetic flux density on total particle removal effi-ciency is similar to that on aggregation coefficient. Before particles are saturatedly magnetized, their total removal effi-ciency increases with an increase in the magnetic flux density. Higher removal efficiency can also be caused by pro-longing the particle residence time in the magnetic field or increasing their mass concentration. The particle numbermedian diameter decreases with an increase in the total removal efficiency. Calculation results are found to coincideessentially with the experimental data.
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NOx emission from incineration of organic liquid waste in a circulating fluidized bed
Chang-Sui Zhao,Hui-Chao Chen,Yong-wang Li,Duan-Feng Lu 한국화학공학회 2007 Korean Journal of Chemical Engineering Vol.24 No.5
incineration test of a toxic chemical organic waste liquid was conducted on a circulating fluidized bed(CFB) incinerator. The flue gas was measured online with the advanced SAE-19 flue gas analyzer. The effects of severalfactors, in terms of flow rate of waste liquid, ratio of waste liquid injected into dense bed of the CFB, excess air co-efficient, the secondary air fraction and bed temperature on NOx emissions, were verified. The experimental resultsthe excess air coefficient or the bed temperature and those decrease with increase in the ratio of waste liquid injectedinto the dense bed of the CFB or the secondary air fraction. During the test runs, NOx concentration in flue gas metthe national regulation on NOx emissions due to suppresive effect of low temperature and staged combustion in CFBon NOx formation.
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