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RISS 인기검색어
- 검색키워드
- 저자 : Camila R Correa (검색결과 3 건)
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Bioavailability of plant pigment phytochemicals in Angelica keiskei in older adults
Camila R Correa,C-Y. Oliver Chen,Giancarlo Aldini,Helen Rasmussen,Carlos F Ronchi,Carolina Berchieri-Ronchi,Soo-Muk Cho,Jeffrey B Blumberg,Kyung-Jin Yeum 한국영양학회 2014 Nutrition Research and Practice Vol.8 No.5
BACKGROUND/OBJECTIVES: Angelica keiskei is a green leafy vegetable rich in plant pigment phytochemicals such as flavonoids and carotenoids. This study examined bioavailability of flavonoids and carotenoids in Angelica keiskei and the alteration of the antioxidant performance in vivo. SUBJECTS AND MATERIALS: Absorption kinetics of phytochemicals in Angelica keiskei were determined in healthy older adults (> 60 y, n = 5) and subjects with metabolic syndrome (n = 5). Subjects consumed 5 g dry Angelica keiskei powder encapsulated in gelatin capsules with a low flavonoid and carotenoid liquid meal. Plasma samples were collected at baseline, 0.5, 1, 2, 3, 4, 5, 6, 7, and 8 h. Samples were analyzed for flavonoids and carotenoids using HPLC systems with electrochemical and UV detection, respectively, and for total antioxidant performance by fluorometry. RESULTS: After ingestion of Angelica keiskei increases in plasma quercetin concentrations were observed at 1-3 and 6-8 hr in the healthy group and at all time points in the metabolic syndrome group compared to baseline (P < 0.05). Plasma lutein concentrations were significantly elevated in both the healthy and metabolic syndrome groups at 8 hr (P < 0.05). Significant increases in total antioxidant performance were also observed in both the healthy and the metabolic syndrome groups compared to baseline (P < 0.05). CONCLUSIONS: Findings of this study clearly demonstrate the bioavailability of phytonutrients of Angelica keiskei and their ability to increase antioxidant status in humans.
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Antiadipogenic Activity of γ-Oryzanol and Its Stability in Pigmented Rice
Igor Otavio Minatel,이윤미,윤해림,윤영,한상익,Camila Renata Correa,Denise Fecchio,YEUMKYUNG JIN 한국식품영양과학회 2016 Journal of medicinal food Vol.19 No.7
γ-Oryzanol, a prevalent compound in pigmented rice varieties, has been reported to ameliorate obesity-associated metabolic disorders. Antiadipogenic activities of γ-oryzanol were determined in human adipose-derived mesenchymal stem cells and mouse-derived 3T3-L1 cells. γ-Oryzanol significantly decreased lipid accumulation and reduced glycerol-3-phosphate dehydrogenase activities in both adipocytes. In addition, γ-oryzanol in four pigmented rice varieties (black with giant embryo, brown, sugary brown, and red) was stable when stored at 4°C and also at room temperature for 22 weeks, whereas other bioactives such as lutein and β-carotene were stable only at −80°C. Furthermore, the yield of γ-oryzanol from these rice varieties was significantly increased through steaming and roasting processes. Therefore, γ-oryzanol exerts antiadipogenic activity by suppressing adipocyte differentiations and is stable in pigmented rice for an extended period of time during storage and after cooking. Thus, the intake of pigmented rice may be a useful strategy for preventing obesity.
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Fat-Soluble Bioactive Components in Colored Rice Varieties
Igor Otavio Minatel,한상익,Giancarlo Aldini,Mara Colzani,Nirupa R. Matthan,Camila Renata Correa,Denise Fecchio,YEUMKYUNG JIN 한국식품영양과학회 2014 Journal of medicinal food Vol.17 No.10
Bioactive components in rice vary depending on the variety and growing condition. Fat-soluble components such as c-oryzanol, tocopherols, tocotrienols, carotenoids, and fatty acids were analyzed in brown, sugary brown, red, and black rice varieties using established high-performance liquid chromatography (HPLC) and GC methodologies. In addition, these colored rice varieties were further analyzed using a high-resolution liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS) (LTQ-Orbitrap XL) to identify the [M-H]- ions of c-oryzanol, ranging from m/z 573.3949 to 617.4211. The highest content of tocopherols (a-, 1.5; c-, 0.5 mg/100 g) and carotenoids (lutein 244; trans-b carotene 25 lg/100 g) were observed in black rice; tocotrienols (a-, 0.07; c-, 0.14 mg/100 g) in red rice, and c-oryzanol (115 mg/100 g) in sugary brown rice. In all colored rice varieties, the major fatty acids were palmitic (16:0), oleic (18:1n-9), and linoleic (18:2n-6) acids. When the c-oryzanol components were further analyzed by LC-MS/MS, 3, 10, 8, and 8 triterpene alcohols or sterol ferulates were identified in brown, sugary brown, red, and black rice varieties, respectively. Such structural identification can lead to the elucidation of biological function of each component at the molecular level. Consumption of colored rice rich in beneficial bioactive compounds may be a useful dietary strategy for achieving optimal health.
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