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      • Poster Session : PS 1583 ; Lung Cancer : Mimicking Metastatic Lung Tumor: A Case of Primary Squamous Cell Lung Carcinoma with a Literature Review

        ( Bomi Park ),( Kwang In Park ),( Sung Min Kim ),( Jin Whan Kim ),( Chung Sik Lee ),( Jae Wook Jeong ),( Dong Il Park ),( Jae Young Moon ),( Jeong Eun Lee ),( Sung Soo Jeong ),( Ju Ock Kim ),( Sun You 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

        A 84-year-old man presented with chronic cough lasted for a year. Posterior-anterior upright methods of chest roentgenography showed multiple metastatic lung nodules in both lung fi eld. And bronchoscopy showed masses in the accessory bronchus in right distal trachea side and anterior basal trunk in right lower lobe. Therefore, he was underwent histological examination for each lesion. The results of histology had been reported in the necrotic tissue and aspergillosis, respectively. However, we thought it`s a result of the contamination, he was underwent further evaluation. A percutaneous needle biopsy revealed poorly differentiated carcinoma of unknown origin. In PET-CT and brain MRI, we found a single cerebellar metastatic lesion and multiple metastatic muscle lesions. Strangely, SUV values of lung nodules were not high but there was increased uptake in paraesophageal area in the PET-CT. Additional duodenoscopic examination proved no abnormality. In order to fi nd the origin site of cancer, we conducted additional immunohistochemial studies, and as a result, p63 and CK5/6 were positive, TTF-1 and napsin-A were negative, respectively. At last, we defi nitely diagnosed as squamous lung cancer and he had underwent chemotherapy. We experienced a casediscovered in multiple metastatic lung nodules that is different from the characteristics of universal squamous lung cancer of central invasion. So we would like to discuss differential diagnosis from metastatic cancer and sarcoidosis which can have similar image fi nding.

      • SCOPUSKCI등재

        Factors Influencing Vaccination in Korea: Findings From Focus Group Interviews

        Park, Bomi,Choi, Eun Jeong,Park, Bohyun,Han, Hyejin,Cho, Su Jin,Choi, Hee Jung,Lee, Seonhwa,Park, Hyesook The Korean Society for Preventive Medicine 2018 예방의학회지 Vol.51 No.4

        Objectives: Immunization is considered one of the most successful and cost-effective public health interventions protecting communities from preventable infectious diseases. The Korean government set up a dedicated workforce for national immunization in 2003, and since then has made strides in improving vaccination coverage across the nation. However, some groups remain relatively vulnerable and require intervention, and it is necessary to address unmet needs to prevent outbreaks of communicable diseases. This study was conducted to characterize persistent challenges to vaccination. Methods: The study adopted a qualitative method in accordance with the Consolidated Criteria for Reporting Qualitative Research checklist. Three focus group interviews were conducted with 15 professionals in charge of vaccination-related duties. The interviews were conducted according to a semi-structured guideline, and thematic analysis was carried out. Data saturation was confirmed when the researchers agreed that no more new codes could be found. Results: A total of 4 main topics and 11 subtopics were introduced regarding barriers to vaccination. The main topics were vaccine hesitancy, personal circumstances, lack of information, and misclassification. Among them, vaccine hesitancy was confirmed to be the most significant factor impeding vaccination. It was also found that the factors hindering vaccination had changed over time and disproportionately affected certain groups. Conclusions: The study identified ongoing unmet needs and barriers to vaccination despite the accomplishments of the National Immunization Program. The results have implications for establishing tailored interventions that target context- and group-specific barriers to improve timely and complete vaccination coverage.

      • Slide Session : OS-ALG-01 ; Allergy : Progranulin Level Correlates with Degree of Airway Obstruction in Asthma Patients

        ( So Young Park ),( You Sook Cho ),( Bomi Shin ),( Hyo Jung Kim ),( So Young Park ),( Sun Young Yoon ),( Gyong Hwa Hong ),( Kyoung Young Lee ),( Mi Young Park ),( Sun Joo Park ),( Hyouk Soo Kwon ),( T 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

        Background: Progranulin is a pleiotrophic protein known to function in various physiological and disease processes. Progranulin concentration negatively correlated with mediators of neutrophilic inflammation in COPD and it was implicated to have an anti-in. ammatory role. However, it has not been studied in asthma and speci. cally through what mechanistic pathway progranulin exerts its anti-in. ammatory effect. As a pilot study, we aimed to identify the presence of progranulin in asthma in order to relate with mechanism study in the future, which is another typical chronic airway in. ammatory disease. Methods: Progranulin levels in serum were measured by ELISA in asthma patients (n=475) and normal subjects (n=43) and was compared with pulmonary function and other various clinical parameters. Results: Progranulin concentration was significantly lower in asthmatics than in healthy subjects (25.51±6.72 vs 33.92±10.99, p<0.001). Progranulin level was compared within asthma patients according to their degree of airway obstruction, and the level showed positive correlation with FEV1% predicted. (R=0.400, p<0.001) Patients diagnosed with asthma/COPD overlap syndrome(n=39) showed lower progranulin level (21.88±5.96 vs 25.84±6.70, p<0.001) and poor lung function (FEV1% predicted, 57.00±17.63 vs 77.20±18.81, p<0.001) compared with patients with asthma(n=436) when subgroup analysis was performed. Conclusions: The results demonstrate progranulin concentration is lower in asthmatics and the level correlates with the degree of airway obstruction. Progranulin may be associated with pathogenesis of severe asthma with fixed airway obstruction.

      • SCOPUSKCI등재

        The Pyramid of Injury: Estimation of the Scale of Adolescent Injuries According to Severity

        Han, Hyejin,Park, Bomi,Park, Bohyun,Park, Namsoo,Park, Ju Ok,Ahn, Ki Ok,Tak, Yang Ju,Lee, Hye Ah,Park, Hyesook The Korean Society for Preventive Medicine 2018 Journal of Preventive Medicine and Public Health Vol.51 No.3

        Objectives: Due to their developmental characteristics, adolescents have a higher probability than other age groups of experiencing injuries caused by accidents, violence, and intentional self-harm. The severity and characteristics of injuries vary by the intentionality and mechanism of injury; therefore, there is a need for a national-level estimate of the scale and the severity of injuries in adolescents that takes these factors into account. Methods: By using data from the Emergency Department-based Injury In-depth Surveillance Data, National Emergency Department Information System, the Korean National Hospital Discharge In-depth Injury Survey, and cause of death statistics, we calculated the emergency department (ED) visit rate, hospitalization rate, and death rate of injuries per 100 000 adolescents for each injury mechanism. The calculated rates were used to generate the injury pyramid ratio (ratio of death rate to hospitalization rate to ED visit rate) to visualize the scale and the severity of the injury. Results: The mortality rate in adolescents due to injury was 10/100 000; the corresponding rates for hospitalization and ED visits were 1623 and 4923, respectively, resulting in an injury pyramid ratio with the general pyramid form, with a 1:162:492 ratio of deaths to hospitalizations to ED visits. The mortality rate due to suicide/intentional self-harm was 5/100 000, while 35 were hospitalized for this reason and 74 made ED visits. The pyramid ratio of 1:7:15 for intentional self-harm/suicide showed a steep pyramidal form, indicating considerable lethality. The mortality rate due to motor vehicle collisions (MVCs) was 3/100 000; 586 were hospitalized for this reason, while 1023 made ED visits. The pyramid ratio of 1:195:341 for MVCs showed a gradual pyramid form, indicating that the lethality was low and the scale of injury was high. Conclusions: The main categories of injuries in adolescents were visualized in pyramid form, contributing to an understanding of the scale of each injury by mechanism in terms of levels of death, hospitalization, and ED visits. These findings will be helpful for understanding how to prioritize injuries in adolescents.

      • SCOPUSKCI등재SCIE

        Cancer risk based on alcohol consumption levels: a comprehensive systematic review and meta-analysis

        Seunghee Jun(Seunghee Jun),Hyunjin Park(Hyunjin Park),Ui-Jeong Kim(Ui-Jeong Kim),Eun Jeong Choi(Eun Jeong Choi),Hye Ah Lee(Hye Ah Lee),Bomi Park(Bomi Park),Soon Young Lee(Soon Young Lee),Sun Ha Jee(Su 한국역학회 2023 Epidemiology and Health Vol.45 No.-

        OBJECTIVES: Alcohol consumption is a well-established risk factor for cancer. Despite extensive research into the relationship between alcohol consumption and cancer risk, the effect of light alcohol consumption on cancer risk remains a topic of debate. To contribute to this discourse, we conducted a comprehensive systematic review and meta-analysis. METHODS: Our systematic review aimed to investigate the associations between different levels of alcohol consumption and the risk of several cancer types. We focused on analyzing prospective associations using data from 139 cohort studies. Among them, 106 studies were included in the meta-analysis after a quantitative synthesis. RESULTS: Our analysis did not find a significant association between light alcohol consumption and all-cause cancer risk (relative risk, 1.02; 95% confidence interval, 0.99 to 1.04), but we observed a dose-response relationship. Light alcohol consumption was significantly associated with higher risks of esophageal, colorectal, and breast cancers. Light to moderate drinking was associated with elevated risks of esophageal, colorectal, laryngeal, and breast cancers. Heavy drinking was also found to contribute to the risk of stomach, liver, pancreas, and prostate cancers, thereby increasing the risk of almost all types of cancer. Additionally, females generally had lower cancer risks compared to males. CONCLUSIONS: Our findings highlight that cancer risks extend beyond heavy alcohol consumption to include light alcohol consumption as well. These findings suggest that there is no safe level of alcohol consumption associated with cancer risk. Our results underscore the importance of public health interventions addressing alcohol consumption to mitigate cancer risks.

      • KCI등재후보

        간호대학생의 문화적 역량과 문화 간 의사소통 관계

        유현정(Yoo, Hyunjung),김관희(Kim, Kwanhee),이하정(Lee, Hajeong),박보미(Park, Bomi),박수빈(Park, Subin),박주희(Park, Juhui),박진희(Park, Jinhui),반민주(Ban, Minjoo),임지현(Lim, Jihyun),박준후(Park, Junhoo),이예은(Lee, Yee Eun) 한국농촌간호학회 2019 한국농촌간호학회지 Vol.14 No.2

        Purpose: This study was done to identify the cultural capacity of college nursing students and the relationship of intercultural communication. Methods: The participants were 200 students in colleges of nursing from 6 universities in C city, who understood the purpose of the study and agreed to participate. Collected data were analyzed with t-test, ANOVA, correlation analysis, and stepwise regression analysis using SPSS/WIN 22.0. Results: Cultural sensitivities in this study (r=.372, p<.001), cultural knowledge (r=.399, p=.001), cultural awareness (r=.547, p<.001), and cultural technology (r=.550, p<.001) each showed a statistically significant correlation with intercultural communication skills. Conclusion: The results of this study show that reinforcement of the cultural and intercultural communication ability of college nursing students, in-depth exploration of the cultural area and religious inspection, cultural and professional backgrounds, assessment and consideration of cultural characteristics, nursing diagnosis, and health appropriate to the cultural background. It is suggested that education such as service provision should be conducted systematically.

      • KCI등재

        Incidence-Based versus Prevalence-Based Approaches on Measuring Disability-Adjusted Life Years for Injury

        Park, Bohyun,Park, Bomi,Lee, Won Kyung,Kim, Young-Eun,Yoon, Seok-Jun,Park, Hyesook The Korean Academy of Medical Sciences 2019 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.34 No.11

        <P><B>Background</B></P><P>Injury represents an important aspect of disease that affects everyone at some point in their lives. To better understand and prevent these injuries, various analytical methods have been developed to assess both the magnitude and features of injury burden. In this study, we attempted to estimate the injury burden of Korea in 2014 by comparing the prevalence-based approach used by the Global Burden of Diseases (GBD) team and the World Health Organization against an alternative incidence-based approach, and to assess the different implications of these measurements.</P><P><B>Methods</B></P><P>The 10th Korean National Hospital Discharge survey data and causes of death statistics in 2014 were used as data sources. Years of life lost (YLL), years lived with disability (YLD) and disability-adjusted life years (DALYs) were calculated using both the incidence- and prevalence-based approaches. The Korean Classification of Diseases (KCD) version 5 diagnostic codes were used to classify the mechanism of injury.</P><P><B>Results</B></P><P>The prevalence-based injury burden tended to be higher (1,670,229 DALYs) than the incidence-based injury burden (1,544,467 DALYs). The elderly population exhibited a higher prevalence-based YLD and DALY relative to incidence-based outcomes. In order of significance, the three most common causes of injury as calculated using an incidence-based approach were road injury, fall, and self-harm, compared with a prevalence-based method, which identified self-harm, road injury, and falls as the most common injuries.</P><P><B>Conclusion</B></P><P>An appropriate prevention program is needed for injuries with potential to cause long-lasting morbidity. Accordingly, a tailored injury-prevention strategy should be developed for each high-risk group.</P>

      • SCIESCOPUSKCI등재

        Trends of Colorectal Cancer Screening Rates in Korea: Korean National Cancer Screening Survey 2005-2020

        ( Bomi Park ),( Yun Yeong Lee ),( Soo Yeon Song ),( Hye Young Shin ),( Mina Suh ),( Kui Son Choi ),( Jae Kwan Jun ) 대한소화기기능성질환·운동학회 2022 Gut and Liver Vol.16 No.6

        Background/Aims: Screening for colorectal cancer (CRC) is important in reducing the morbidity and mortality of CRC. Thus, this study aimed to describe the trends of CRC screening in both organized and opportunistic settings in Korea from 2005 to 2020 according to sociodemographic characteristics. Methods: This study analyzed the data of adults aged 50 to 74 years from the Korean National Cancer Screening Survey. Trends for CRC screening rates (fecal immunochemical test [FIT] within the last year, double-contrast barium enema within the last 5 years, or colonoscopy within the last 10 years for 2005-2018 and FIT within the last year or colonoscopy within the last 10 years for 2019-2020) were analyzed using Joinpoint regression. The trends were also analyzed according to sociodemographic characteristics, including age, sex, monthly household income, education level, and residential area. Results: A total of 29,040 participants were included in the analysis. The CRC screening rate significantly increased from 25.0% to 60.1%, with an annual percent change (APC) of 9.2% between 2005 and 2014, followed by a nonsignificant increase to 64.4% between 2014 and 2020 (APC,1.7%). When the participants were stratified according to sociodemographic factors, the participants with higher household income and education levels generally had higher screening rates. Conclusions: There has been substantial improvement in CRC screening rates in the general Korean population. However, it is necessary to determine why the screening rate has stabilized since 2014 and identify barriers that cause disparities in CRC screening rates among populations with lower socioeconomic status. (Gut Liver 2022;16:930-941)

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