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김상주(Sang-Joo Kim),신준호(Joonho Shin),김윤재(Yun-Jae Kim) 대한기계학회 2002 대한기계학회 춘추학술대회 Vol.2002 No.3
A two-dimensional finite element model for polarization switching in ferroelectric materials developed by Kim and Jiang<SUP>(1)</SUP> and Sang-Joo Kim<SUP>(2)</SUP> is used to predict the formation of domains in a ferroelectric thin film. Initially the ferroelectric film is poled upward and the bottom electrode is grounded. A strong downward de field is imposed on a point of the top surface of the film. A region of switched domains with downward polarization is nucleated and is grown with time. It is found that initially the shape of the nucleated domains is that of a bulgy dagger, but later it turns into the shape of a reversed cup with the lower part wider than the upper part. It can also be concluded that the size of nucleated domains increases with the period of applied electric potential. The present results are qualitatively consistent with experimental observations.
Biodiversity of Arthropods between GM and non-GM Rice Field
SeungTae KIM,SueYeon LEE,HunSung KIM,ChangGyu PARK,SeJin KIM,MyungPyo JUNG,JoonHo-LEE 한국응용곤충학회 2008 한국응용곤충학회 학술대회논문집 Vol.2008 No.05
Biodiversity of arthropods in Cnaphalocrocis medinalis (Lepidoptera: Crambidae) resistant GM rice (CryIAc1) and non-GM rice fields. Sampling was conducted 15 times using sweeping net and electric aspirator. Biodiversity was analyzed with species richness and Shannon diversity index (H’). Total 28,275 arthropod individuals (12,413 in GM rice and 15,862 individuals in non-GM rice) were collected and there were 22 families, 34 genera and 36 species belonging to 8 orders. There were 19 families, 29 genera, 31 species in GM rice and 20 families 32 genera 34 species in non-GM rice fields. There was no significant difference in species richness and species diversity (H’) between GM and non-GM rice. Species diversity was significantly higher in non GM rice in the insect pest group only in middle and late of August .
Park Chan,Kim Jin Hyoung,Kim Pyeong Hwa,Kim So Yeon,Gwon Dong Il,Chu Hee Ho,Park Minho,Hur Joonho,Kim Jin Young,Kim Dong Joon 대한영상의학회 2021 Korean Journal of Radiology Vol.22 No.2
Objective: Clinical outcomes of patients who undergo transarterial chemoembolization (TACE) for single small hepatocellular carcinoma (HCC) are not consistent, and may differ based on certain imaging findings. This retrospective study was aimed at determining the efficacy of pre-TACE CT or MR imaging findings in predicting survival outcomes in patients with small HCC upon being treated with TACE. Besides, the study proposed to build a risk prediction model for these patients. Materials and Methods: Altogether, 750 patients with functionally good hepatic reserve who received TACE as the first-line treatment for single small HCC between 2004 and 2014 were included in the study. These patients were randomly assigned into training (n = 525) and validation (n = 225) sets. Results: According to the results of a multivariable Cox analysis, three pre-TACE imaging findings (tumor margin, tumor location, enhancement pattern) and two clinical factors (age, serum albumin level) were selected and scored to create predictive models for overall, local tumor progression (LTP)-free, and progression-free survival in the training set. The median overall survival time in the validation set were 137.5 months, 76.1 months, and 44.0 months for low-, intermediate-, and high-risk groups, respectively (p < 0.001). Time-dependent receiver operating characteristic curves of the predictive models for overall, LTP-free, and progression-free survival applied to the validation cohort showed acceptable areas under the curve values (0.734, 0.802, and 0.775 for overall survival; 0.738, 0.789, and 0.791 for LTP-free survival; and 0.671, 0.733, and 0.694 for progression-free survival at 3, 5, and 10 years, respectively). Conclusion: Pre-TACE CT or MR imaging findings could predict survival outcomes in patients with small HCC upon treatment with TACE. Our predictive models including three imaging predictors could be helpful in prognostication, identification, and selection of suitable candidates for TACE in patients with single small HCC.
Lee, Hyebin,Kim, Kwangsoo,Woo, Jongmin,Park, Joonho,Kim, Hyeyoon,Lee, Kyung Eun,Kim, Hyeyeon,Kim, Youngsoo,Moon, Kyung Chul,Kim, Ji Young,Park, In Ae,Shim, Bo Bae,Moon, Ji Hye,Han, Dohyun,Ryu, Han Suk American Society for Biochemistry and Molecular Bi 2018 Molecular and Cellular Proteomics Vol.17 No.9
<P>Cytological examination of urine is the most widely used noninvasive pathologic screen for bladder urothelial carcinoma (BLCA); however, inadequate diagnostic accuracy remains a major challenge. We performed mass spectrometry-based proteomic analysis of urine samples of ten patients with BLCA and ten paired patients with benign urothelial lesion (BUL) to identify ancillary proteomic markers for use in liquid-based cytology (LBC). A total of 4,839 proteins were identified and 112 proteins were confirmed as expressed at significantly different levels between the two groups. We also performed an independent proteomic profiling of tumor tissue samples where we identified 7,916 proteins of which 758 were differentially expressed. Cross-platform comparisons of these data with comparative mRNA expression profiles from The Cancer Genome Atlas identified four putative candidate proteins, AHNAK, EPPK1, MYH14 and OLFM4. To determine their immunocytochemical expression levels in LBC, we examined protein expression data from The Human Protein Atlas and in-house FFPE samples. We further investigated the expression of the four candidate proteins in urine cytology samples from two independent validation cohorts. These analyses revealed AHNAK as a unique intracellular protein differing in immunohistochemical expression and subcellular localization between tumor and non-tumor cells. In conclusion, this study identified a new biomarker, AHNAK, applicable to discrimination between BLCA and BUL by LBC. To our knowledge, the present study provides the first identification of a clinical biomarker for LBC based on in-depth proteomics.</P>
Kim, Taeyoung,Lee, Joonho,Kim, Yunkyum,Kim, Jong-Min,Yuan, Zhangfu The Japan Institute of Metals 2009 MATERIALS TRANSACTIONS Vol.50 No.11
<P>In the electronic components and device packaging process, the Cu conductor surface is generally coated with Au and Ni. The Au coating is applied to prevent the oxidation of the Cu surface and enhance the solderability, while the Ni coating is applied as a diffusion barrier between the solder alloy and the Cu substrate, in order to restrict the formation and growth of intermetallic compounds. The dynamic reactive wetting characteristics of Sn-Ag-Cu alloys are related to the properties of the coating materials. In the present study, the dynamic reactive wetting behavior of Sn-Ag-Cu alloys on Cu substrates coated with Ni and Au was firstly investigated on millisecond scale. On the bare Cu surface, the metal droplet rebounded several times due to the poor wettability and started to spread from 1 s and became equilibrated by 20 s, whereas on the Ni/Au coated surface, the metal droplet settled down without rebounding because of the good wettability, which caused it to react instantaneously, and became equilibrated by 1 s.</P>
KIM, SAYUP,ROH, JONGRYUN,HYEONG, JOONHO,KIM, YOUNGHO World Scientific 2017 JOURNAL OF MECHANICS IN MEDICINE AND BIOLOGY Vol.17 No.8
<P>It is generally believed that running on a curved surface is more unstable than running on a flat surface. In this study, the dynamic stability of locomotion on a nonmotorized curved treadmill (NMCT) with three curvature radii was compared with that on a motorized flat treadmill. Sixteen healthy adult men maintained four different self-paced speeds: slow walking, fast walking, jogging, and running. Significant differences were statistically verified using two-way repeated-measures analysis of variance (ANOVA) according to the curvature radii and speeds, and the interaction effects were confirmed. Furthermore, to understand the significant differences between the speed and curvature radius, <I>post hoc</I> analyses were performed using one-way ANOVA. Except for the step width, the other parameters showed differences and correlation effects between the curvature radius and speed. As the curvature radius decreased, the stability decreased at slow speeds (slow walking) but increased at fast speeds (running). However, as the curvature radius increased, the stability increased at slow speeds (slow walking) but decreased at high speeds (running). The study results will help in suggesting the appropriate curvature radius for different user types such as athletes, the elderly, and people who require rehabilitation and will serve as preliminary data for designing the curvature radii of NMCTs.</P>