제주지역에서 브로콜리 노균병 발생 실태 및 품종에 따른 저항성 검정

고순보(Sun Bo Ko),김성배(Seong Bae Kim1),고태신(Tae Sin Ko),홍순영(Sun Young Hong),강성근(Sung Koon Kang),박용봉(Yong Bong Park) 한국원예학회 2008 한국원예학회 학술발표요지 Vol.2008 No.5

Complication of Intraoperative Radiation Therapy (IORT) in Gastric Cancer

김명세(Myung Se Kim),김성규(Sung Kyu Kim),송선교(Sung Kyo Song),김홍진(Hong Jin Kim),권굉보(Koing Bo Kwan),김흥대(Heung Dae Kim) 대한방사선종양학회 1992 Radiation Oncology Journal Vol.10 No.2

영남대학교 의료원 치료방사선과에서 1988년 6월 15일에 위함 환자의 수술중 방사선치료를 시작한 이래 1992년 8월 30일까지 총 58예에서 시도하여 그중 53예에서 IORT를 실시하였으며, 정기적인 추적검사에서 한명의 국소개발 환자도 보고되지 않고 있다. 출혈(3예), 장관폐쇄(3예), 폐혈증(2예), 골수기능저차(1예)를 포함한 총 9예(17%)의 합병증이 보고되었고, 이중 6예(13%)가 사망하였다. IORT(1500cGy), 외부 방사선치료 (-4500cGy)와 강한 항암제를 병합치료 하였음에도 불구하고 주등(수술과 항암제 치료)의 25.2%, 김등(수술 불가능한 환자에서 항암제 투여)의 18%, 리등(수술)의 18.5%, Kraming등(IORT 2800-3500cGy)의 35.3%에 비해 낮은 합병증을 보여 IORT가 위암의 치료에 공헌할 수 있음을 시사하였다. 그러나 비교적 높은 치사율(11.3%)은 더욱 세심한 수술수기 및 수술 후 환자의 치료가 필요하며 외부 방사선치료와 항암제치료의 적절한 시기 조절 및 치료선량의 가감이 필요할 것으로 생각된다. Local control is the important prognostic factor in cancer treatment because local control decrease the relative risk of metastatic spread and increase distant metastasis free survival. IORT is the modality which could increase local control without increasing complication, combined with curative operation. Eventhough we could achieve significant deacreased local failure by IORT and curative resection, it should not be committed as a main treatment modality without proving acceptable complications. Therapeutic Radiology Department of Yeungnam University Medical Center have tried 58 IORT from June 15, 1988 and performed 53 IORT in patients with gastric cancer. No local failure had been reported including interstinal obstrution, hemorrhage, sepsis, and bone marrow depression. These complications could be comparable to Jo's 25.2% (chemotherapy + operation), Kim's 18% (chemotherapy only in inoperable patients), because our treatment regimen is consisted of IORT (1500cGy), external irradiation (--4500cGy) and extensive chemotherapy (FAM, 5FU + MMC, BACOP). Our data encouraged us to re-inforce further IORT in stomach cancer treatment.

경북 성주지역 장수노인의 영양상태(Ⅰ)

백지원(Baek, Ji-Won),구보경(Koo, Bo-Kyung),김규종(Kim, Kyu-Jong),이연경(Lee, Yeon-Kyung),이성국(Lee, Sung-Kook),이혜성(Lee, Hye-sung) 한국영양학회 2000 Journal of Nutrition and Health Vol.33 No.4

경북 성주지역 장수노인의 계절별 식품섭취 상태

백지원(Ji-Won Baek),구보경(Bo-Kyung Koo),김규종(Kyu-Jong Kim),이연경(Yeon-Kyung Lee),이성국(Sung-Kook Lee),이혜성(Hye-Sung Lee) 한국식품영양과학회 2000 한국식품영양과학회지 Vol.29 No.4

본 연구는 우리나라 장수노인들의 식품섭취상태를 분석 평가하고 건강한 장수를 위한 식생활 지침의 설정을 위한 기초자료를 얻고자 수행되었다. 연구 대상은 경상북도 성주군에 거주하는 85세 이상 고령노인 중에서 일상 생활에 문제가 없는 224명이었으며 이들을 대상으로 반복 24시간 회상법을 이용하여 1년간 4회의 계절별 식품 섭취 조사를 실시하였으며 결과를 요약하면 다음과 같다. 계절별 식품군별 섭취량에 있어서 남자노인은 감자류의 섭취량이 여름철에 유의적으로 높고, 버섯류의 섭취량이 가을철에 유의하게 높은 것을 제외하고는 모든 식품군의 섭취량에 있어 계절별 차이가 나타나지 않았다. 여자노인의 경우 곡류, 당류, 두류, 채소류, 과일류, 조미료류, 음료 및 주류, 육류, 우유류, 어패류의 섭취량이 겨울철에 유의하게 높았으며, 종실류, 해조류, 난류의 섭취량은 계절에 따른 차이가 없었다. 조사 대상자들의 연평균 1일 총 식품 섭취량은 594.4±186.1 g이었으며 이 중에서 513.5±161.2 g(86.4%)는 식물성 식품군으로부터 섭취하였고 79.3±56.7 g(13.3%)는 동물성 식품군으로부터 섭취하였다. 섭취량이 가장 높았던 식품군은 곡류였으며그 다음이 채소류, 과일류, 어패류, 음료 및 주류, 조미료류, 두류, 육류, 우유류, 감자류 등의 순이었다. 장수 노인대상자들의 음식별 섭취빈도는 밥류에 있어서는 쌀밥의 섭취비율이 80.1~89.2%로 가장 높았으며 국과 찌개류에서는 쇠고기국, 된장국, 된장찌개의 섭취 비율이 높았다. 어육류 식품의 경우 조기구이의 섭취비율(9.4~12.7%)이 높았으며, 해조류 식품의 경우 김구이의 섭취비율(7.4~20.5%)이 높았고, 각 계절마다 계절식품의 섭취비율이 높았다. 김치류의 경우 배추김치의 섭취비율이 4계절 모두 70% 이상으로 높게 나타났다. 일품요리류는 손쉽게 조리할 수 있는 라면과 국수의 섭취비율이 높았다.<br/> 본 연구의 결과에서 경북 성주지역 장수 노인들의 계절별 식품 섭취량에 있어 겨울철의 식품 섭취량이 다른계절에 비해 유의하게 높았으며, 남자노인보다는 여자노인이 식품섭취에 계절에 의한 영향을 더욱더 많이 받는 것으로 나타났다. 또한 장수 노인들은 가공식품보다는 계절마다 제철에 생산되는 자연 식품의 섭취비율이 높았다. 전반적으로 장수노인들은 소식의 경향을 보였으며 이와 같은 소식습관과 신선한 식물성 식품들의 일상 섭취가 건강한 장수에 영향을 미쳤을 가능성도 있을 것으로 사료된다. The purpose of this study was to estimate food intakes of the long-lived elderly and to obtain the data for establishing dietary guidelines that may be recommended for the general population for the sake of longevity. The subjects of the study were 224 elderly people of age over 85 years living in Kyungpook Sung-Ju area who have no problem in daily living. The food consumption survey was carried out seasonally by the repeated 24-hr recall method for one year. The subject group for this study was composed of 58 males and 166 females, the average age being 87 years old. Food intakes of the winter were more than any other seasons. The mean daily total food intake per capita was 594.4 g, 513.5 g (86.4%) from plant foods and 79.3 g (13.3%) from animal foods. The sequence of high intakes of food groups were cereals, vegetables, fruits, fishes, legumes and meats. Boiled white rice, beef soup, soybean paste soup, soybean paste stew, broiled yellow croaker, kimchi, ra myon and broiled noodles were consumed most frequently. In conclusion, the subjects consumed much more plants foods than animal foods and consumed more natural and seasonal foods than processed foods and also showed food habits of eating small meals. Dietary habits of eating small meals containing abundant amount of fresh plant foods might partially contribute to the longevity of the subjects.

The Effects of NEES on PARP Expression and Cell Death in Rat Cerebral Cortex After Ischemic Injury

Sung Won Kim,Jung Sook Lee,Ki Mai Um,Ji Sung Kim,Suk Hee Lee,Yoo Rim Choi,Nyeon Jun Kim,Bo Kyoung Kim,Mi Suk Cho,Joo Hyun Park,Soon Hee Kim 국제물리치료학회 2010 Journal of International Academy of Physical Ther Vol.1 No.2

The majority of strokes are caused by ischemia and result in brain tissue damage, leading to problems of the central nervous system including hemiparesis, dysfunction of language and consciousness, and dysfunction of perception. The purpose of this study was to investigate the effects of Poly(ADP-ribose) polymerase(PARP) on necrosis in neuronal cells that have undergone needle electrode electrical stimulation(NEES) prior to induction of ischemia. Ischemia was induced in male SD rats(body weight 300g) by occlusion of the common carotid artery for 5 min, after which the blood was reperfused. After induction of brain ischemia, NEES was applied to Zusanli(ST 36), at 12, 24 and 48 hours. Protein expression was investigated using immuno-reactive cells, which react to PARP antibodies in cerebral nerve cells, and Western blotting. The results were as follows: In the cerebral cortex, the number of PARP reactive cells after 24 hours significantly decreased(p<.05) in the NEES group compared to the GI group. PARP expression after 24 hours significantly decreased(p<.05) in the NEES group compared to the GI group. As a result, NEES showed the greatest effect on necrosis- related PARP immuno-reactive cells 24 hours after ischemia, indicating necrosis inhibition, blocking of neural cell death, and protection of neural cells. Based on the results of this study, NEES can be an effective method of treating dysfunction and improving function of neuronal cells in brain damage caused by ischemia.

High metabolic tumor volume and total lesion glycolysis are associated with lateral lymph node metastasis in patients with incidentally detected thyroid carcinoma

Kim, Bo Hyun,Kim, Seong-Jang,Kim, Keunyoung,Kim, Heeyoung,Kim, So Jung,Kim, Won Jin,Jeon, Yun Kyung,Kim, Sang Soo,Kim, Yong Ki,Kim, In Joo Springer Japan 2015 Annals of nuclear medicine Vol.29 No.8

<P><B>Objective</B></P><P>The objective of this study was to investigate whether total lesion glycolysis (TLG) and metabolic tumor volume (MTV) measured by <SUP>18</SUP>F-fluorodeoxyglucose (<SUP>18</SUP>F-FDG) positron emission tomography/computed tomography (PET/CT) could predict the aggressiveness and lymph node metastasis (LNM) in patients with incidentally detected differentiated thyroid carcinoma.</P><P><B>Methods</B></P><P>A total 358 patients with focal FDG-avid thyroid incidentaloma during cancer evaluation were enrolled. Among 235 patients in whom fine-needle aspiration biopsy was performed, 51 patients underwent total thyroidectomy with LN dissection. We analyzed the relationship between volume-based parameters and clinicopathologic characteristics.</P><P><B>Results</B></P><P>The mean age and tumor size were 57.1 ± 11.3 years and 1.15 ± 0.81 cm, respectively. The prevalence of malignancy was 21.7 % (51/235). When SUV<SUB>max</SUB> > 5.91, MTV2.5 > 2.05 cm<SUP>3</SUP>, and TLG2.5 > 9.09 were used as cutoff points, sensitivity, specificity, and area under curve (AUC) for prediction of lateral LNM were 77.9, 69.1 %, 0.716 (<I>P</I> = 0.047), 77.8, 88.1 %, 0.839 (<I>P</I> < 0.001), 77.8, 85.1 %, and 0.815 (<I>P</I> = 0.002), respectively. However, MTV and TLG had no value in prediction of central LNM, extrathyroidal extension, and multifocality. On comparison ROC curve analysis, the MTV and TLG showed the statistical differences for the prediction of lateral LNM compared with SUV<SUB>max</SUB> (all <I>P</I>’s < 0.05).</P><P><B>Conclusions</B></P><P>This study has shown for the first time that volume-based PET functional parameters had a significant value for the prediction of lateral LNM in incidentally detected PTC. These results suggest that higher MTV and TLG can be potential new risk factors for preoperative risk stratification. The usefulness of TLG and MTV in preoperative risk stratification in patients with PTC needs to be confirmed in further large studies.</P>

18, 19세기 시화(詩話) 편찬자의 서간문에 나타난 시학(詩學) 담론

김보성 ( Kim Bo-sung ) 한국어문교육연구회 2015 어문연구(語文硏究) Vol.43 No.1

본고는 18, 19세기에 詩話를 편찬한 김창협, 신정하, 성해응, 김정희 등이 서간문에서 펼친 시학 담론의 양상을 살폈다. 조선 문인의 시문관은 시화를 비롯하여 서간문, 서발문 등에 주로 보이는데, 여기에서는 분석 대상을 ‘조선 후기 시화 편찬자’로 한정하고 그들의 ‘서간문’을 중점적으로 살펴, 당시 시문 비평에 깊은 관심을 보였던 조선 문인 사이에서 오간 시학 담론의 실체를 파악하는 데 초점을 맞추었다. 18, 19세기 시화 편찬자의 서간문에서 시학 담론은 크게 시 학습[學詩]에 관한 담론과 시 작문[作詩]에 관한 담론으로 나뉘는데, 18세기에는 ‘初唐·盛唐·中唐·晩唐 네 시기를 고루 학습’, ‘기발한 격조를 추구하는 열풍을 경계’하는 것에 관한 논제가, 19세기에는 ‘唐詩의 경지에 오르기 위해 淸詩부터 단계별로 학습’, ‘시어·시구를 정미하게 고증’하는 것에 관한 논제가 두드러지게 나타난다. 이를 통해 19세기 시학 담론이 18세기에 비해 학시 범위의 논의 수준은 광범위해지고, 작시 방법의 논의 수준은 정교해지는 일련의 변화를 파악할 수 있다. The current paper addresses discussions on poetry in the letters by 18th-19th ShiHua(詩話: collection of criticisms about poets) writers including Kim Chang-huep(金昌協), Shin Geong-ha(申靖夏), Sung Hae-eung(成海應), and Kim Jeong-hui(金正喜). Other than ShiHua(詩話), Joseon(朝鮮) Dynasty writers’ views on poetry and prose can be observed also from letters, prefaces or epilogues. In particular, this paper focuses on 18th-19th ShiHua(詩話) writers and their letters in order to examine discussions on poetics among literary men of Joseon(朝鮮) who were interested in poetry criticism. In the letters by poet-critics during the 18th and 19th centuries, discussions on poetry can be divided into two types. One type of discussion is on methods for studying poet[學詩法], while the other type of discussion is on methods for writing poet[作詩法]. Topics of the letters during the 18th century were focused on covering all different periods of Tang(唐) including ChuTang(初唐), ShengTang(盛唐), ZhongTang(中唐), WanTang(晩唐) and resisting fancy, emotional expressions. However, topics of the letters during the 19th century were focused on particular topics such as ‘step by step learning from Cheng(淸) poet to become a Tang(唐) poet’ and ‘deep thinking on poetic words and verses.’ Through these changes in topics in different periods, the current paper recognizes that discussions on poetry in the 19th century covered more various areas and were more sophisticated than those in the 18th century.

P068 : The sebum secretion characteristics in trunk and its association with facial sebum secretion

( Bo Ri Kim ),( Mi Young Chun ),( Sung Ae Kim ),( Sang Woong Youn ) 대한피부과학회 2014 대한피부과학회 학술발표대회집 Vol.66 No.2

Background: To the best of our knowledge, there were no studies performed on the objective analysis of truncal sebum secretion. Objectives: The goal of this study was to investigate the characteristics of sebum secretion in face and trunk according to the each zone. We also evaluated the correlation between sebum secretion of face and trunk. Methods: The casual sebum levels (CSLs) of the five facial areas and ten trunk areas in 35 Korean females with acne were measured, using Sebumeter®. The areas of face and trunk were reclassified into low zone (U, FL, BL) and high zone (T, FH, BH) by CSLs. Statistical analysis was performed, according to the each zone. Results: The face showed higher CSLs than the trunk. The T zone showed higher CSLs than that of the U zone in the face. The FH zone had higher CSLs than that of the FL zone, and the BH zone had higher CSLs than that of the BL zone in the trunk. CSLs showed a significant positive correlation between T zone and FH zone. In addition, there was a significant positive correlation in the CSLs of FH zone and BH zone.Conclusion: This was the first study to report the characteristics of sebum secretion in trunk and the significant correlations between the CSLs of face and trunk using an objective, bioengineering method. We suggest that face and trunk can be divided into low zone and high zone according to the CSLs, and the patients who have higher CSLs in face are more likely to have higher CSLs in trunk.

Effect of antimalarial agents by the inhibition of Plasmodium falciparum Calpain

Bo Yoon Chang(장보윤),Pyo Yun Cho(조표연),Hyun Park(박현),Sung Yeon Kim(김성연) 한국환경독성학회 2010 한국독성학회 심포지움 및 학술발표회 Vol.2010 No.11

Direct synthesis of pyrazoles from esters using <i>tert</i>-butoxide-assisted C–(C&z.dbd;O) coupling

Kim, Bo Ram,Sung, Gi Hyeon,Ryu, Ki Eun,Lee, Sang-Gyeong,Yoon, Hyo Jae,Shin, Dong-Soo,Yoon, Yong-Jin The Royal Society of Chemistry 2015 Chemical communications Vol.51 No.44

<P>This paper describes the direct synthesis of pyrazoles from esters that comprises two sequential reactions: tert-butoxide-assisted C-C(=O) coupling reaction to yield beta-ketonitrile or alpha,beta-alkynone intermediates, and condensation by hydrazine addition. The method reported allows for easy control of the regioselectivity and structure of substituents at N-1, C-3, C-4 and/or C-5 positions.</P>