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고식적 체외수정시술과 난자 세포질내 정자주입술에 의해 태어난 아이의 주산기 결과 및 선천성 기형 발생빈도의 비교 연구
임정은,유근재,이종표,이문섭,현우영,전진현,홍수정,송지홍,송인옥,백은찬,최범채,손일표,궁미경,강인수,전종영,박인서,Lim, Jeong-Eun,Yoo, Keun-Jai,Lee, Jong-Pyo,Lee, Moon-Seob,Hyun, Woo-Young,Jun, Jin-Hyun,Hong, Soo-Jeong,Song, Ji-Hong,Song, In-Ok,Paik, 대한생식의학회 1998 Clinical and Experimental Reproductive Medicine Vol.25 No.3
The safety of ICSI as a novel procedure of assisted fertilization may be assessed by the health of the baby born. In order to evaluate the safety of ICSI, perinatal outcome and congenital anomaly of the babies born after ICSI were compared with those of babies born after IVF (control group). We analysed the clinical data from the obstetric and pediatric records, including the information obtained through telephone. The results are as follows; Mean gestational age $({\pm}SEM)$ and birth weight in singleton pregnancy were $38.8{\pm}1.9$ weeks and $3209.7{\pm}501.9gm$ in IVF group, $39.0{\pm}2.2$ weeks and $3289.9{\pm}479.5gm$ in ICSI group, respectively. Mean gestational age and birth weight in twins were $36.8{\pm}2.1$ weeks and $2512.8{\pm}468.0gm$ in IVF group, $36.5{\pm}2.8$ weeks and $2492.7{\pm}537.1gm$ in ICSI group. In IVF group, perinatal mortality rates were 8.5 in singletons and 56.6 in twins; for the ICSI singletons and ICSI twins, the perinatal mortality rates were 11.6 and 49.0, respectively. The incidence of congenital malformations was 3.6% (8/224) in IVF group and 2.1% (4/188) in ICSI group, there was no statistical difference (p>0.05, Fisher's exact test). The incidence of major congenital anomalies was 0.9% (2/224; pulmonary artery hypoplasia, renal cystic dysplasia) in IVF group and 1.1% (2/188; holoprosencephaly, Cri du chat syndrome) in ICSI groups (p>0.05, Fisher's exact test). Similarly, there was no significant difference in incidence of minor congenital anormalies 2.7% (6/224) in IVF group and 1.1% (2/188) in ICSI group respectively (p>0.05, Fisher's exact test). In conclusion, there was no difference in the perinatal outcome and the incidence of congenital anomalies between the babies born after ICSI and those after conventional IVF.
약물유해반응 이후 처방의 변경 유형과 치료 결과: Lamotrigine 관련 사례 분석
강정은 ( Jeong Eun Kang ),이경훈 ( Kyeong Hun Lee ),서비취 ( Bi Chwi Seo ),임정미 ( Jung Mi Lim ),서성연 ( Sung Yeon Suh ),조윤숙 ( Yoon Sook Cho ),서동인 ( Dong In Suh ) 대한천식알레르기학회 2023 Allergy Asthma & Respiratory Disease Vol.11 No.2
Purpose: This study aimed to describe the desperate situation where the clinician should make decisions to further manage patients having experienced adverse drug reaction (ADR) to lamotrigine that is indicated to not easily controlled neuropsychiatric diseases. Methods: A descriptive analysis was done by thoroughly reviewing medical records of patients who were reported to have ADR to lamotrigine in a regional drug-safety center between 2010 and 2018. Results: Eighty-four cases of lamotrigine-related ADRs occurred in 80 patients. Skin lesions were most commonly observed in 70 cases (83.3%) and 14 cases (16.7%) had severe ADRs. Sixty-three subjects (78.8%) discontinued lamotrigine, while 17 (21.3%) continued it. At the time of discontinuation, 30.0% were prescribed aromatic antiepileptic drugs. Among 4 subjects who were eventually prescribed lamotrigine again after a period of discontinuation, 3 (75.0%) experienced its recurrence. Among patients who had taken alternative medications, the incidence of ADRs was higher in those being prescribed aromatic antiepileptic drugs than in the others being prescribed other than aromatic antiepileptic drugs (P=0.013). Regarding the control of underlying diseases, as many as 65 (86.7%) and 68 (90.7%) failed to reach maintaining the resolved state from 6 months and 12 months after the substitution, respectively. Conclusion: Patients can be easily trapped between the recurrence of ADRs and the treatment failure to a certain drug like lamotrigine, in which we can hardly find a reasonable alternative to manage them. (Allergy Asthma Respir Dis 2023;11:72-76)
채명정(Myeong-Jeong Chae),소향숙(Hyang Sook So),이지선(Ji-Sun Lee),이수연(Su-Yeon Lee),이정화(Jeong-Hwa Lee),임정인(Jeong-In Lim) 전남대학교 간호과학연구소 2009 Nursing and Health Issues(NHI) Vol.14 No.1
Ⅰ. 서 론 Ⅱ. 연구 방법 Ⅲ. 연구 결과 Ⅴ. 논 의 Ⅵ. 결론 및 제언
김종진(Jong Jin Kim),임정식(Jeong Sik Lim),공덕경(Duck Kyung Gong),최경희(Kyoung Hee Choi),정인권(In Gweon Jung),정만홍(Man Hong Jung),이재우(Jae Woo Lee) 대한내과학회 1990 대한내과학회지 Vol.39 No.4
N/A The left atrial systolic time intervals and Doppler mitral flow velocity measurements were performed in 28 patients of essential hypertension and in 12 normal controls(Group I). The hypertensive patients were divided into two groups according to the absence (Group II, 12 cases) and the presence (Group III, 16 cases) of the fourth heart sound on phonocardiegram. Left atrial systalic time interva) indices included atrial pre-eiection period (APEP), corrected atrial pre-eiection period (APEEc), atrial eiection time (AET) and the ratio of APEP/AKT. The hypertensive patients with the fourth heart sound had a shorter APEPc (78±9 vs 94±11 ms, P<0.01), a longer AET (168±13 vs 144±11 ms, P<0.01), and a shorter APEPc/AET (0.48±0.08 vs 0.66±0.12, P<0.01). The ratio of mitral peak flow velocity during atrial systole to peak flow veloclty in early diastole (A/E ratio) was signifieantly higher in Group III compared with values in Group II (1.54±0.28 vs 1.29±0.31), as well as there being a significant increase of left ventricular wall thickness (2.88±0.38 vs 2.57±0.34 cm, P<0,05). There were no signilicant differences in the left atrial systolic time intervals and the A/E ratio between Group I and Group II. In concluslon, left atria) systolic time intervals can be a good method in the quantitative assessinent of left atrial function in hypertensive patients with left ventricular hypertrophy.
신이식 100예에서 이식신의 예후에 영향을 미치는 인자
편도철(Do Chul Pyun),정인권(In Kweon Jung),임창범(Chang Bum Lim),양영란(Young Ran Yang),임정식(Jeong Sik Lim),김종진(Jong Jin Kim),하봉준(Bong Jun Ha),김홍기(Hong Khee Kim),이시래(Si Rhae Lee),이승도(Sung Do Lee),류현열(Hyun Yul Rhew 대한내과학회 1989 대한내과학회지 Vol.37 No.5
N/A It has been reported that many factors other than HLA and the mode of immunosuppression influence the results of renal transplantation. The factors are constantly changing with the advances in surgical techniques and introduction of Cyclosporin-A s-A), etc. We analyzed the possible prognostic factors in 100 cases of renal allograft which were performed by the transplantation team of Kosin Medical College from Dec. 1984 to Aug. 1988. Detailed results are presented for the several factors as follows: 1) HLA and the mode of immunosuppression. Excluding 9cases of graft failure due to non-immunological causes, the actuarial graft survival in 3 years was 100% in the E3LA-II) group, 95.1% in the HLA-HID group and 84.6% in the LUR group. In the HLA-HID group, the 3 year graft survival (3YGS) was 96.8% in the Cs A+P treated group and 93.3% in the Aza+P treated group, and the difference in these 2 groups was not significant statistically (p>0.1). Numbers of patients with serum creatinine equal or above 2 mg/dl were 5 of 17cases (29.4%) in the Aza+P treated HLA-HID group, and 8 of 47cases (17.1%) in the Cs-A+P treated HLA-HID group, but the difference was not significant statistically (p>0.1). 2) Pretransplant transfusions. Twenty-seven cases which were transfused with more than 10 units of packed red cells were 100% in 3YGS and the other cases were 97.8% in 3YGS, And there was no significant difference between Aza+P and Cs A+P treated HLA-HID groups in relation to transfusion (p>0.1), 3) Donor and recipient age. The 3YGS in donors older than 50 years and in those 50 years old and under were 93.796 and 94.895, respectively, The percentages of cases with serum creatinine equal or above 2mg/dl were 26. 5% in the older than 50 years group and 12.3% in the other group, but the difference was not significant statistically (p>0.1). Thirteen cases older than 60 years were 10096 in 3YGS. Recipient age had no significant effect on 3YGS between the older than 50 years group and the other group (p>0.1). 4) Donor and recipient sex. The 3YGS was highest (100%) in the male to male group and lowest (87.5%) in the male to female group, but the difference was not significant in these 2 groups (p>0.1). 5) Minor ABO incompatibility. Seventeen cases with minor ABO incompatibility were 100% in 3YGS, and in remaining compatible 74 cases, the 3YGS was 93.4% and there was no significant difference (p>0.1). In summary, the 3YGS was higherst in the HLA-ID group, and there was no signifcant difference in 3YGS between Aza+P and Cs A+P treated HLA-HID groups. And the elder (more than 50 years or 60 years) donor group did not show lower 3YGS than the younger age group despite somewhat worse graft function. There appears to be a minimal effect with mismatch of sex and minor ABO incompatibility. And the fact that there is no significant relation between pretransplant transfusion and 3YGS seems to be due to DST, which was done in all cases except HLA-ID and 2cases of the HLA-HID group.
김병각(Byong Kak Kim),임정한(Jeong Han Lim),윤인희(In Hee Yoon),박옥진(Ock Jin Park),김혜숙(Hae Sook Kim) 한국생약학회 1971 생약학회지 Vol.2 No.2
In order to detect poisonous or physiologically active constituents in the Higher Fungi growing in Korea, fortythree species including two varieties were collected in Kyung Ki and Chung Cheong Buk Do Provinces and subjected to systematic extraction with two kinds of organic solvents. The extracts were examined for alkaloid by adding alkaloid reagents. Of these fungi, three species, Geaster fimbriatus, Lampteromyces japonicus and Pseudocolus schellenbergiae, gave positive confirmatory tests.
다양한 치태조절기구가 타이타늄 임프란트의 표면조도와 형태에 미치는 영향
최승환,임정수,송인택,김형섭,Choi, Seoung-Hwan,Lim, Jeong-Su,Song, In-Taeck,Kim, Hyoug-Seop 대한치주과학회 1998 Journal of Periodontal & Implant Science Vol.28 No.2
The purpose of this' study was to compare surface roughness and morphologic changes after use of various plaque control devices to titanium implant surfaces. The study materials were 6 ITI titanium implants($Bonefit^{(R)}$) and 5 plaque control devices. 6 implants were divided into 6 different groups and instrumented by each plaque control devices as follows. 1) Group I : untreated control 2) Group II : Titanium curette(Titanium $curette^{(R)}$, 3i) 80 vertical/horizontal strokes 3) Group III : Plastic curette($Implacare^{(R)}$, Hu-Friedy) 80 vertical/horizontal strokes 4) Group N : Plastic tip-ultrasonic scaler($Amdent^{(R)}$, Amdent) 160 seconds 5) Group V : Rotating interdental brush($Identobrush^{(R)}$, Identoflex) 160 seconds 6) Group VI : Abrasive rubber cup polisher($Zircate^{(R)}$, Prophy paste, Dentsply) 160 sec-onds. All specimens were prepared for evaluation by surface roughness tester, optical stereomicroscopy(OM) and scanning electron microscopy(SEM). The Ra and Rt mean values of the tested specimens were 1) Group I ($Ra=0.170{\pm}0.007{\mu}m$, $Rt=1.297{\pm}0.016{\mu}m$) 2) Group II ($Ra=0.209{\pm}0.006{\mu}m$, $Rt=1.602{\pm}0.110{\mu}m$) 3) Group III ($Ra=0.179{\pm}0.001{\mu}m$, $Rt=1.429{\pm}0.055{\mu}m$) 4) Group IV ($Ra=0.182{\pm}0.005{\mu}m$, $Rt=1.511{\pm}0.085{\mu}m$) 5) Group V ($Ra=0.301{\pm}0.008{\mu}m$, $Rt=1.882{\pm}0.131{\mu}m$) 6) Group VI ($Ra=0.147{\pm}0.010{\mu}m$, $Rt=1.059{\pm}0.021{\mu}m$) In Ra values, experimental group II, V, VI were statistically significant different when compared with control. OM and SEM observation showed that experimental group III, IV were minimal changes when compared with control and group VI was smoothest among other experimental groups. The results suggested that plastic curette and plastic tip-ultrasonic scaler were predictable devices to titanium implant surface.
의도적으로 철쭉 섭취 후 발생된 성인 전신 중독 증상 1례
정상민,이승한,임정수,윤상열,유승,이진웅,김승환,유인술,유연호,Jeong, Sang-Min,Lee, Seung-Han,Lim, Jeong-Soo,Yoon, Sang-Yeol,Ryu, Seung,Lee, Jin-Woong,Kim, Seung-Whan,Yoo, In-Sool,You, Yeon-Ho 대한임상독성학회 2009 대한임상독성학회지 Vol.7 No.2
It is well known that Rhododendron sclippenbashii contains the toxic material grayanotoxin. So, Koreans do not eat it, but they do eat azalea although it contains grayanotoxin. That is why there have been no reports about Rhododendron sclippenbashii intoxication after ingesting it intentionally, not accidentally. In this case, the patient was admitted to the emergency room with several toxic symptoms after intentionally consuming 50 blossoms of Rhododendron sclippenbashii to get rid of thirst. Treatment with saline infusion and atropine was successful and the outcome was favorable enough in this case to produce a complete cure without any sequelae at discharge. But toxic symptoms were seen for 24 hours, although the symptoms usually fade in 9 hours. Therefore, we should carefully treat and observe, for over 24 hours, the patient who intentionally ingests about 50 blossoms of Rhododendron sclippenbashii.