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김종진(Jong Jin Kim),임정식(Jeong Sik Lim),공덕경(Duck Kyung Gong),최경희(Kyoung Hee Choi),정인권(In Gweon Jung),정만홍(Man Hong Jung),이재우(Jae Woo Lee) 대한내과학회 1990 대한내과학회지 Vol.39 No.4
N/A The left atrial systolic time intervals and Doppler mitral flow velocity measurements were performed in 28 patients of essential hypertension and in 12 normal controls(Group I). The hypertensive patients were divided into two groups according to the absence (Group II, 12 cases) and the presence (Group III, 16 cases) of the fourth heart sound on phonocardiegram. Left atrial systalic time interva) indices included atrial pre-eiection period (APEP), corrected atrial pre-eiection period (APEEc), atrial eiection time (AET) and the ratio of APEP/AKT. The hypertensive patients with the fourth heart sound had a shorter APEPc (78±9 vs 94±11 ms, P<0.01), a longer AET (168±13 vs 144±11 ms, P<0.01), and a shorter APEPc/AET (0.48±0.08 vs 0.66±0.12, P<0.01). The ratio of mitral peak flow velocity during atrial systole to peak flow veloclty in early diastole (A/E ratio) was signifieantly higher in Group III compared with values in Group II (1.54±0.28 vs 1.29±0.31), as well as there being a significant increase of left ventricular wall thickness (2.88±0.38 vs 2.57±0.34 cm, P<0,05). There were no signilicant differences in the left atrial systolic time intervals and the A/E ratio between Group I and Group II. In concluslon, left atria) systolic time intervals can be a good method in the quantitative assessinent of left atrial function in hypertensive patients with left ventricular hypertrophy.