CDMA방식 중계기용 전력증폭기의 설계에 관한 연구

김한석,김훈용,김대중,이종악,Kim, Han-Suk,Kim, Hoon-Yong,Kim, Dae-Jyung,Lee, Jong-Arc 한국전기전자학회 1999 전기전자학회논문지 Vol.3 No.2

본 논문에서는 CDMA 방식 중계기용 전력증폭기의 선형특성을 향상시키기 위해 기존의 전치왜곡 방식과 전방귀환 방식을 혼합한 전력증폭기를 설계 제작하였다. CDMA방식의 이동통신 시스템은 기존의 아날로그 셀룰라 방식과는 사용 스펙트럼 대역폭이 훨씬 크며 증폭기의 비선형성에 의한 채널사이의 혼변조 왜곡을 충분히 제거하여야만 통신이 가능하기에 선형성이 우수한 전력증특기가 필수적으로 요구된다. 본 논문에서 제작한 전력증폭기는 37dBm, 2-tone 인가시의 IMD 특성이 -50dBc로써 나타났으며, 불요방사 특성도 IS-95 기준을 만족하는 $fc{\pm}\;885kHz$에서 약 -46dBc, $fc{\pm}\;1.98MHz $ 에서는 약 -52dBc로 나타났다. In this paper, a new type of linearization technique proposed, in which the predistortor was added to the feedforward linearizer. As the input power level is applied to HPA, the gain and phase characteristics of the amplifier are also varied. By using of the predistorter the amplitude imbalance and phase imbalance is kept constant. Experimental results are present for Korea PCS frequency band. The center frequency of the feedforward amplifier is 1.843.75 MHz with 1.23 MHz bandwidth. The 2-tone intermodulation distortion at 37dBm output power is about -50dBc, and spurious emission are -46dBc at $fc{\pm}\;885KHz\;and\;-52dBc\;at\;fc\;{\pm}1.98MHz$, respectively.

조현병 환자에서 불안자극에 대한 선택적 주의 편향과 환청과의 연관성 : 예비 연구

김한석,한진희,홍승절,정종현,임현국,김태원,엄유현,채정호,이경욱,서호준,Kim, Han-Suk,Han, Jin-Hee,Hong, Seung-Chul,Jeong, Jong-Hyun,Lim, Hyun-Kook,Kim, Tae-Won,Um, Yoo-Hyun,Chae, Jeong-Ho,Lee, Kyoung-Uk,Seo, Ho-Jun 대한불안의학회 2016 대한불안의학회지 Vol.12 No.1

Objective : This study was conducted to evaluate the relationships between selective attention bias for fear stimuli and hallucination in patients with schizophrenia Method : A total of 66 patients with schizophrenia admitted to psychiatry clinics were included in the study. Selective attention bias was measured by the dot-probe task. Patient symptoms were measured using the Positive and Negative Symptom Scale, Psychotic Symptom Rating Scale (PSYRATS), Korean version of the Scale to Assess Unawareness of Mental Disorder, and Clinical Global Impression-Severity scale. Results : Selective attention bias was correlated with the hallucination subscale of PSYTATS (r=0.268, p=0.029). No correlation was found between selective attention bias and other clinical measures. There was no significant difference, but a statistical trend was found (p=0.092) in hallucination severities between the biased and non-biased groups. Conclusion : The results suggest that selective attention bias for fear stimuli is associated with auditory hallucination. This preliminary study suggests the possibility of correlation between auditory hallucination in the psychotic domain and anxiety of the affective component.

십전대보탕액(十全大補湯液)을 투여(投與)하여 가토간손상(家兎肝損傷)의 회복(回復)에 관(關)한 실험적(實驗的) 연구(硏究)

김한석,Kim, Han-Suk 대한한방내과학회 1976 大韓韓方內科學會誌 Vol.1 No.1

The SIB ZUN DAE BO TANG is one of the prevailing tonics appeared at first time on TAE PYUNG HOE MIN HAW ZE GUK BANG in Song’s dynasty and have been widely used up to now. To observe the metabolic effects of Thioacetamide from the SIB ZUN DAE BO TANG, the following experiment was performed. 1. The activation of G.O.T. and G.P.T. to blood serum have been decreased when Thioacetamide was administrated into the rabbit. 2. The coefficiency of the SIB JUN DAE BO TANG appears in 3 hours after administrate and it decreases gradually along with it’s time(1st, 2nd, 3rd day) but the coefficiency of the G.P.T. was more apparent on 2nd, 3rd and 5th day. 3. When administrating Thioacetamide, the total amount of cholesterol grows rapidly up to 3rd day and it continuously grows after the 3rd day. But when administrating SIB ZUN DAE BO TANG, the cholesterol amount in blood grows up to 3rd day, but it decreases gradually after it on the other day. The conclusion of the above experiments shows that the prescription (SIB ZUN DAE BO TANG) improves the metabolic deficiency and the recovery and remedy of diseases.

PIN 다이오드를 이용한 C-Band 위상 변위기의 설계에 관한 연구

김한석,김훈영,이창식,이종악,Kim, Han-Suk,Kim, Hoon-Yong,Lee, Chang-Sik,Lee, Jong-Arc 한국전기전자학회 1999 전기전자학회논문지 Vol.3 No.2

본 논문에서 C-밴드 6-비트 변위기의 설계와 제작을 하였고 각 비트에 대한 설계 기술을 기술하였다. $5.625^{\circ},\;11.25^{\circ},\;22.5^{\circ}$ 그리고 $45^{\circ}$ 위상 비트는 부하선로 방식, $90^{\circ}$ 위상 비트는 하이브리드 결합 방식 그리고 $180^{\circ}$ 위상 비트는 가변선로 방식을 각각 마이크로스트립 구리 기판 위에 적용하였다. In this paper, a C-band 6-bit phase shifter is designed and fabricated and design techniques for each phase bit are represented. We applied the loaded line type to $5.625^{\circ},\;11.25^{\circ},\;22.5^{\circ}\;and\;45^{\circ}$ phase bits and the hybrid coupled type to $90^{\circ}$ phase bit and the switched line type to $180^{\circ}$ phase bit, respectively on a microstrip copper substrate.

Recurrent Herpes-Stomatitis Mimicking Acute Necrotizing Ulcerative Gingivitis

김한석,이석근,박영욱,Kim, Han-Seok,Lee, Suk-Keun,Park, Young-Wook Korean Association of Maxillofacial Plastic and Re 2011 Maxillofacial Plastic Reconstructive Surgery Vol.33 No.1

Herpes simplex is caused by viruses of the herpesvirus hominus family. HSV have four categories: type 1, 2, 6, and 8. Generally HSV-1 affects the mouth. Once infected by HSV, the person's infection is permanent. Retrograde transport through adjacent neural tissue to sensory ganglia leads to a lifelong latent infection. Recently, we treated a patient with recurrent herpes-stomatitis mimicking acute necrotizing ulcerative gingivitis (ANUG). The results were satisfactorty so we report this case. 31 years old male patient showed sore throat, gingival ulceration, palpable both submandibular lymph node, and sulcular pus formation around posterior decayed teeth. This is the third time he has suffered from this symptom. Tentative diagnosis was acute necrotizing ulcerative gingivitis. Antibiotic therapy was started. But, intraoral symptom got worse in process of time. Especially ulcer of marginal gingiva got worse. Viral disease was suspected. We carried out viral cultivation. At the same time topical application of antiviral ointment (herpecid$^{(R)}$) was performed on oral ulcer unilaterally for the purpose of diagnosis and reducing pain experimentally. The next day pain was decreased dramatically on application area. Basing on the viral cultivation and clinical effect of antiviral ointment (herpecid$^{(R)}$), we have diagnosed it as a recurrent herpes-stomatitis and concluded that viral infection was major cause of disease and bacterial infection was secondary.

지중환경 내 유류오염 토양에 대한 생물학적 정화 개선 연구

김한석(Han-Suk Kim),김나경(Na-Kyung Kim) 대한환경공학회 2022 대한환경공학회 학술발표논문집 Vol.2022 No.11

종설 : 신생아저혈소판증

김한석 ( Han Suk Kim ) 대한주산의학회 2006 大韓周産醫學會雜誌 Vol.17 No.4

Ureaplasma urealyticum의 집락에 따른 신생아의 임상 양상

임인숙 ( In Suk Lim ),최창원 ( Chang Won Choi ),김병일 ( Byeong Il Kim ),김상덕 ( Sang-duk Kim ),이진아 ( Jin A Lee ),김이경 ( Eu Kyung Kim ),김한석 ( Han Suk Kim ),최중환 ( Jung Hwan Choi ) 대한주산의학회 2007 Perinatology Vol.18 No.1

목적: Ureaplasma urealyticum (U. urealyticum)은 태아와 신생아 폐렴의 중요한 원인으로 밝혀져 있으며 미숙아에서 기관지폐 이형성증의 발생과 관련이 있다고 보고되어졌다. 저자들은 U.urealyticum의 집락 여부에 따른 신생아들의 임상양상을 비교 분석하고자 하였다. 방법: 2003년 6월부터 2006년 7월까지 분당 서울대학교병원 신생아 중환자실에 입원한 환아 중 출생 첫날 U. urealyticum에 대한 검사를 시행한 476명을 대상으로 하였다. 소변 또는 기관지 폐포 흡인액중에서 PCR 또는 배양검사를 시행하여 U. urealyticum 양성군과 음성군간의 신생아 호흡 곤란증후군 및 기관지폐 이형성증의 빈도를 비교하였다. 결과: 출생 첫날 U. urealyticum에 대한 검사를 시행한476명 중 재태 연령 32주 미만은 136명이었고 재태 연령 32주 이상은 340명이었다. 재태 연령 32주 미만의 환아에서는 18명(13%)이 U.urealyticum 양성이었고 이들에서 기관지폐 이형성증의 발생빈도는 U. urealyticum 음성군에 비해 유의하게 높았고(p=0.058), 신생아 호흡 곤란 증후군의 발생빈도는 적었다(p=0.043). 생후 3일의 말초 혈액에서 총백혈구수는 U. urealyticum 양성군에서 유의하게 증가되어 있었으며(p=0.003), 이차이는 중성구에서 더 뚜렷하였다(p=0.001). 총 IgM과 CRP는 U. urealyticum 집락과 유의한 관계가 없었으며 산모 양수에서 U. urealyticum의 집락여부와 환아의 U. urealyticum의 집락여부도 유의한 관계가 없었다. 재태 연령 32주 이상의 환아에서는 23명(7%)이 U. urealyticum 양성이었고 이들에서 기관지폐 이형성증의 발생은 없었으며 신생아 호흡 곤란 증후군의 발생빈도는 감소하지 않았다 (p=0.605). 환아의 총 IgM은 U. urealyticum 양성군에서 증가하였으나(p<0.006) 환아의 총백혈구와 CRP는 유의한 증가를 보이지 않았다. 산모의 U. urealyticum 집락여부와 환아의 U. urealyticum의 집락여부도 유의한 상관관계가 없었다(p=0.21). 결론: U. urealyticum의 집락은 재태 연령 32주 미만의 미숙아에서 기관지폐 이형성증의 발생빈도를 증가시켰고 신생아 호흡 곤란 증후군의 발생빈도는 감소시켰다. Objective: Ureaplasma urealyticum colonization is a significant cause of fetal and neonatal pneumonia and is associated with the prevalence of bronchopulmonary dysplasia (BPD) in preterm infants. This study was aimed to evaluate the relationship between U. urealyticum colonization and neonatal morbidity Methods: We tested 476 infants for U. urealyticum on the first day of life among infants admitted to the neonatal intensive care unit of Bun-dang Seoul National University Hospital from June 2003 to July 2006. Urine and endotracheal aspirates were processed by PCR (polymerase chain reaction) or culture for U. urealyticum colonization. We compared the morbidity in the colonized group with the non-colonized group. Results: The study group consisted ot 136 infants less than 32 weeks of gestational age and 340 infants more than 32 weeks of gestational age. In infants less than 32 weeks of gestational age, 18 (13%) of 136 infants had 1 or more positive specimens by culture or PCR. BPD occurred more in the colonized group than in the non-colonized group (p=0.058) and respiratory distress syndrome (RDS) occurred significantly less in the colonized group (p=0.043). Total WBC counts on the third day of life was significantly increased in the colonized group (p=0.003) and this significance was prominent in the neutrophil fraction (p=0.001). There was no significant relation between U. urealyticum colonization and IgM levels nor C-reactive protein (CRP) level nor U. urealyticum colonization of the mother. Twenty-three(7%) of 340 infants more than 32 weeks of gestational age had 1 or more positive specimens by culture or PCR. BPD didn`t occur and RDS didn`t decrease significantly in the colonized group (p=0.605). Total IgM levels didn`t increase significantly in the colonized group (p<0.006) but total WBC counts and CRP levels didn`t increase significantly in the colonized group. There was no significant relation between U. urealyticum colonization and U. urealyticum colonization of the mother (p=0.21). Conclusion: U. urealyticum colonization in infants less than 32 weeks of gestational age was associated with an increased prevalence of BPD and a decreased prevalence of RDS.

극소 저출생 체중아에서 SMOFlipid의 투여가 미숙아 질환 예방에 미치는 영향: Cholestasis 예방 중심으로

김문진 ( Moon Jin Kim ),배혜정 ( Hye Jung Bae ),조윤숙 ( Yoon Sook Cho ),김귀숙 ( Kwi Suk Kim ),김향숙 ( Hyang Suk Kim ),이혜숙 ( Hye Suk Lee ),이주영 ( Ju Young Lee ),김이경 ( Ee Kyung Kim ),김한석 ( Han Suk Kim ) 한국정맥경장영양학회 2013 한국정맥경장영양학회지 Vol.5 No.2

Purpose: Very low birth weight infants (VLBWI) are found to have a higher incidence of cholestasis due to long-term total parenteral nutrition (TPN). Although there have been some studies on relationships between omega-3 fatty acids and reduced incidence of cholestasis, the advantages that the fatty acids provide for premature infant diseases have not yet been fully understood. The aim of this study was to evaluate the advantages of SMOFlipid, a lipid emulsion product that contains omega-3 over other lipid emulsion products that do not. Methods: The medical records of 182 newborn (127 boys and 55 girls) were reviewed retrospectively between April 2010 and August 2012. These infants were born with a birth weight of <1,500 g and administered either of lipid emulsions (Intra MCT 20% or SMOFlipid) from birth to a full-feeding condition at our neonatal intensive care unit. Cholestasis is defined as serum direct bilirubin (DB) >1.0 mg/dL when total bilirubin (TB) is <5 mg/dL or DB/TB ratio is >20% when TB >5 mg/dL. Results: The incidence of cholestasis was found to be lower in the SMOFlipid group than in the medium-chain triglyceride/long chain triglyceride (MCT/LCT) group (7.3% [4/55] versus 18.9% [24/127], P=0.046). At the start of lipid emulsion administration (day 0), the baseline bilirubin level showed no significant difference between the two groups. However, the maximum value of DB on days 7∼ 14 was lower in the SMOFlipid group than in the MCT/ LCT group (0.8 [0.3∼2.2] versus 1.1 [0.3∼2.8] mg/dL, P= 0.030). The DB/TB ratio was also lower in the SMOFlipid group than in the MCT/LCT group (10.2% [4.9%∼40.0%] versus 24.1% [5.1%∼62.5%], P=0.002). Conclusion: This study concluded that SMOFlipid was effective in the prevention of cholestasis in VLBWI. Therefore, omega-3-containing lipid emulsion can be highly recommended in premature babies, especially in VLBWI who require TPN support. (JKSPEN 2013;5(2):67-75)

미숙아에서 모세 혈관종의 임상양상

김선녀 ( Seon Nyo Kim ),이주영 ( Juyoung Lee ),신승한 ( Seung Han Shin ),최창원 ( Chang Won Choi ),김이경 ( Ee Kyung Kim ),김한석 ( Han Suk Kim ),김병일 ( Beyong Il Kim ),최중환 ( Jung Hwan Choi ) 대한주산의학회 2015 Perinatology Vol.26 No.3

Purpose: Capillary hemangiomas occur more frequently in preterm infants. We aimed to describe the clinical course of capillary hemangiomas in preterm infants. Methods: The records of preterm infants with a gestational age (GA) of <35 weeks who were admitted to two tertiary neonatal intensive care units from January 2004 to December 2013 and had capillary hemangiomas were reviewed retrospectively. Subgroup analysis of between infants of GA <30 weeks and GA 30-34+6 weeks were done and ad hoc analysis comparing study population and matched preterm infants without hemangioma for investigation of differences in clinical characteristics. Results: Of the 2,772 preterm infants, 112 (4%) infants developed capillary hemangiomas. The majority (91.9 %) of them had a solitary hemangiomas with the trunk was the most commonly involved site (43%). Three quarters of the patients were treated with topical corticosteroid, propranolol or laser treatment. When we divided this population as who were born before or after GA 30 weeks, there was no difference at postmenstrual age (PMA) of onset of capillary hemangiomas (median [IQR], 36+4 [30+5-40+5] vs. 36+2 [33+6-41+1] weeks, P= 0.275). The age at involution of capillary hemangiomas was also not differ between two groups (median [IQR], 7.75 [3.75-12.25] vs. 7.5 [4-13.75] months, P=0.425). There were no statistical differences between preterm infants with capillary hemangiomas and their age, weight and sex matched control preterm infants without hemangiomas in the neonatal and maternal factors. Conclusion: The development of capillary hemangiomas occurred at approximately 36 to 37weeks of PMA regardless of prematurity in preterm infants. Capillary hemangiomas of preterm infants resolved spontaneously and disappear completely by around 7 months of corrected age.