소아 림프관종의 OK-432 병변내 주사요법

김경헌,김현학,이석구,서정민,장원영,이병붕,Kim, Kyung-Hun,Kim, Hyun-Hahk,Lee, Suk-Koo,Seo, Jeong-Meen,Chang, Weon-Young,Lee, Byung-Boong 대한소아외과학회 2001 소아외과 Vol.7 No.2

Lymphangioma is a congenital malformation of the lymphatic system, commonly seen in the neck. Operation was the treatment of choice but it is difficult to resect the lymphangiomas completely. The aim of this study is to evaluate the result of intralesional injection of OK-432 as a treatment strategy of lymphangioma in children. Medical records of 51 cases of lymphangioma from March 1996 to February 2001 were reviewed retrospectively. Intralesional injection of 0.1mg OK-432 in 10ml normal saline was performed after the aspiration of as much fluid as possible. The location of the lesion was the face and neck in 26 patients, the chest wall in 14, the extremities in 9, and the abdominal wall in 2. The cystic type was present in 45 patients and the cavernous type in 6. Four postoperative recurrent cases were included. Fluid aspiration from the lesion was impossible in 5 patients. Development of fever after injection was observed in 27 patients and local inflammatory reaction was in 5 patients. There was no scar formation at injection sites. Complete shrinkage was observed in 20 patients, remarkable shrinkage in 23, slight shrinkage in 3, and no response in 5. Cystic type or aspiration-possible cases showed better outcome than cavernous type or aspiration-impossible cases. All of four recurrent cases after surgical excision showed at least remarkable shrinkage. These results indicate that intralesional injection of OK-432 is a safe and satisfactory treatment modality of lymphangiomas in children and might be considered as a treatment of choice, even in recurrent cases.

초임부에서의 무통분만의 임상적 경과

구미경 ( Mi Kyung Koo ),김현희 ( Hyun Hee Kim ),조삼현 ( Sam Hyun Cho ),김승룡 ( Seung Ryong Kim ),조수현 ( Su Hyun Jo ),김경태 ( Kyung Tae Kim ),문형 ( Hyung Moon ),황윤영 ( Yoon Yoong Hwang ),김경헌 ( Kyung Hyun Kim ),유중배 ( 대한산부인과학회 2001 Obstetrics & Gynecology Science Vol.44 No.3

N/A Objective : Our purpose was to determine the effect of epidural analgesia on the first phase of labor and mode of delivery of nulliparous women. Methods : We studied 170 nulliparous women at near-term who underwent spontaneous and induced labor at the Department of Obstetrics and Gynecology, Hanyang University Hospital from January 1999 to May 2000 prospectively. Eighty women who were received epidural analgesia for pain relief were compared to ninety women as control group. Cesarean delivery was performed when indicated. Results : The demographic characteristics of the two groups were similar with respect to age, height, weight, gestational weeks, and gravida. The two groups had the same cervical dilatation at the time of analgesia. There were no statistically significant difference between two groups. The length of the first phase of labor was same between two groups(558.4±50.4 min. vs 452.1±46.7 min.). There were statistically significant differences in the instrument delivery and cesarean section rate between two groups(43 vs. 32, 8 vs. 16 respectively). Conclusion : Epidural analgesia provides safe and effective intrapartum pain control and may be administered without undesirable effects on the first phase of labor and delivery.

평균기온과 식생의 영향을 고려한 격자기반 일 지표토양온도 예측 모형 개발

최지현 ( Chi Hyun Choi ),최대규 ( Dae Gyu Choi ),최현일 ( Hyun Il Choi ),김경헌 ( Kyung Hyun Kim ),김상단 ( Sang Dan Kim ) 한국물환경학회 2012 한국물환경학회지 Vol.28 No.1

Land surface temperature in ecohydrology is a variable that links surface structure to soil processes and yet its spatial prediction across landscapes with variable surface structure is poorly understood. And there are an insufficient number of soil temperature monitoring stations. In this study, a grid-based land surface temperature prediction model is proposed. Target sites are Andong and Namgang dam region. The proposed model is run in the following way. At first, geo-referenced site specific air temperatures are estimated using a kriging technique from data collected from 60 point weather stations. Then surface soil temperature is computed from the estimated geo-referenced site-specific air temperature and normalized difference vegetation index. After the model is calibrated with data collected from observed remote-sensed soil temperature, a soil temperature map is prepared based on the predictions of the model for each geo-referenced site. The daily and monthly simulated soil temperature shows that the proposed model is useful for reproducing observed soil temperature. Soil temperatures at 30 and 50 cm of soil depth are also well simulated.

선천성 식도 폐쇄증의 예후 판정

김현학,정현아,김경헌,김정한,이석구,Kim, Hyun-Hahk,Jeong, Hyeon-A,Kim, Kyung-Hun,Kim, Jung-Han,Lee, Suk-Koo 대한소아외과학회 2001 소아외과 Vol.7 No.1

The aims of this study were to evaluate the prognostic predictabilities of the risk classifications (Waterston, Montreal, and Spitz), preoperative treatment of pneumonia and the length of esophageal gap in esophageal atresia. Twenty-five cases of esophageal atresia were reviewed retrospectively. The data was analyzed with Likelihood ratio test for trend and Fisher's exact test. Survival rates were 100.0 % in group A and B, and 60.0 % in group C according to Waters ton classification (p=0.027). By Montreal classification, 95.7 % in group I and 50.0 % in group II (p=0.086). By Spitz classification, 95.5 % in group I and 66.7% in group II (p=0.159). The survival rate was 85.7 % in the patients with pneumonia preoperatively treated and 94.4% in the patients without pneumonia. The difference was not significant (p=0.490). Survival rate in the patients with long gap (${\geq}$3cm) was 50.0 % and 100.0 % in patients with short gap (<3cm) with significant difference (p=0.020). The Waterston classification could be modified into two groups because the prognosis of both group A and B were the same. Preoperative pneumonia does not seem to be a risk factor. The length of the esophageal gap showed prognostic value.

선천성 횡격막 탈장의 지연수술 결과

이석구,김현학,김경헌,장윤실,박원순,Lee, Suk-Koo,Kim, Hyun-Hahk,Kim, Kyung-Hun,Chang, Yun-Sil,Park, Won-Soon 대한소아외과학회 2001 소아외과 Vol.7 No.1

Congenital diaphragmatic hernia (CDH) in the past was considered a surgical emergency requiring immediate operation. Several groups now advocate preoperative stabilization and delayed surgery. The treatment strategy for CDH in this institution is delayed surgery after preoperative stabilization. The aim of this study was to evaluate the results of delayed surgery. A retrospective review of 16 neonates with CDH was performed. Surfactant. conventional mechanical ventilation. high frequency oscillation. and nitric oxide were utilized for preoperative stabilization as necessary. The difference in outcome between two groups differentiated by the duration of the preoperative stabilization periods with mechanical ventilation (${\leq}$ 8 hours and > 8 hours) was determined. Chi-square test was used to analyze the data. There were 7 right-sided hernias and 9 left. The average duration of stabilization was 32.4 hours. Hepatic herniation through the defect was found in 6 cases and all died. The most common postoperative complication was pneumothorax. The mortality rate of the right side hernia was higher than the left (85.7% vs. 33.3%. p=0.036). Mortality rate of the group (N=8) whose preoperative stabilization period was 8 hours or less was better than that (N=6) whose preoperative stabilization period was more than 8 hours (25.0% vs. 83.3%. p=0.031). The overall mortality rate was 56.3%. The better prognosis was noticed in left side hernia. no liver herniation, or shorter preoperative stabilization period.

위염전 1예

김현학,이석구,김경헌,Kim, Hyun-Hahk,Lee, Suk-Koo,Kim, Kyung-Hun 대한소아외과학회 2000 소아외과 Vol.6 No.2

Gastric volvulus is a rare surgical disorder in the pediatric population. We experienced a case of gastric volvulus. A 2-year-old boy was admitted to hospital with abdominal distension. An upper gastrointestinal series showed reversal of the greater and lesser curvatures. Surgical exploration revealed an organoaxial volvulus of the stomach, and anterior gastropexy was performed.

확인적 요인모형을 이용한 낙동강 유역의 오염특성 분석

김미아 ( Mi Ah Kim ),강태구 ( Tae Gu Kang ),이혁 ( Hyuk Lee ),신유나 ( Yu Na Shin ),김경헌 ( Kyung Hyun Kim ) 한국물환경학회 2012 한국물환경학회지 Vol.28 No.1

The study was conducted to analyze the spatio-temporal changes in water quality of the major 36 sampling stations of Nakdong River, depending on each station, season using the 17 water quality variables from 2000 to 2010. The result was verified to interpret the characteristics of water quality variables in a more accurate manners. According to the Principal component analysis (PCA) and Exploratory factor analysis (EFA) results; the results of these analyses were identified 4 factors, Factor 1 (nutrients) included the concentrations of T-N, T-P, NO3-N, PO4-P, DTN, DTP for sampling station and season, Factor 2 (organic pollutants) included the concentrations of BOD, COD, Chl-a, Factor 3 (microbes) included the concentrations of F.Coli, T.Coli, and Factor 4 (others) included the concentrations of pH, DO. The results of a Cluster analysis indicated that Geumhogang 6 was the most contaminated site, while tributaries and most of the down stream sites of Nakdong River were mainly affected by each nutrients (Factor 1) and organic pollutants (Factor 2). The verification consequence of Confirmatory factor analysis (CFA) from Exploratory factor analysis (EFA) result can be summarized as follows: we could find additional relations between variables besides the structure from EFA, which we obtained through the second-order final modeling adopted in CFA. Nutrients had the biggest impact on water pollution for each sampling station and season. In particular, It was analyzed that P-series pollutant should be controlled during spring and winter and N-series pollutant should be controlled during summer and fall.

초 광대역 광 증폭기용 광역 파장 필터 설계

김창준(Chang-Jun Kim),황현용(Hyun-Yong Hwang),김경헌(Kyung-Heon Kim),신종덕(Jong-Dug Shin) 한국통신학회 2000 한국통신학회 학술대회논문집 Vol.2000 No.7

물수지 및 식생 동역학 모의를 위한 생태수문모형 개발

최대규 ( Dae Gyu Choi ),최현일 ( Hyun Il Choi ),김경헌 ( Kyung Hyun Kim ),김상단 ( Sang Dan Kim ) 한국물환경학회 2012 한국물환경학회지 Vol.28 No.4

A simple ecohydorlogic model that simulates hydrologic components and vegetation dynamics simultaneously based on equations of soil water dynamics and vegetation`s growth and mortality is discussed. In order to simulate ungauged watersheds, the proposed model is calibrated with indirected estimated observation data set; 1) empirically estimated annual vaporization, 2) monthly surface runoff estimated by NRCS-CN method, and 3) vegetation fraction estimated by SPOT/VEGETATION NDVI. In order to check whether the model is performed well with indirectly estimated data or not, four upper dam watersheds (Andong, Habcheon, Namgang, Milyang) in Nakdong River watershed are selected, and the model is verified.

정형외과 수술후통에 대한 지주막하강내 Morphine 의 영향

김완식,박동호,유희구,황재현,김경헌,황영희,전세웅 대한마취과학회 1985 Korean Journal of Anesthesiology Vol.18 No.4

To assess the postoperative analgesic effect of intrathecal morphine, it was given with 0.5% isobaric bupivacaine intrathecally after orthopedic surgery. The patients were divided into three groups. In group Ⅰ(control group) 0.5% bupivacaine 3 ml was administered with normal saline 0.2 ml to 10 patients. In group Ⅱ(experimental group) 0.5% bupivacaine 3 ml was administered with morphine hydrochloride 0.5 mg to 10 patients and in group Ⅲ(experimental group) morphine hydrochloride 1.0 mg to 10 patients. The duration of the postoperative analgesic effect, frequency of analgetic jection and incidence of side effects wore checked and compared. The results of this study were as follows: 1) The mean time of duration of analgesia was prolonged significantly in group Ⅱ compared to group Ⅰ(p<0.05) and very significantly in group Ⅲ(p<0.005) and also a significant difference between group Ⅱ and group Ⅲ(p<0.01). 2)The frequency of analgetic injection in the postoperative period was lower in group Ⅱ than in groupⅠ and no patient was injected in group Ⅲ. 3) The mean time to maximal analgesic block was 19.5 minutes and the mean time to mxaimal motor block was 17.7 minutes. There was no difference among the three groups. 4) The mean time of recovery from the sensory blockade and motor blockade was 6.1 hours and 4.2 hours. Htere was no difference among the three groups. 5) Among the three groups there was little change in a the cardiovascular system due to suppression of the autonomic nervous system after induction of spinal anesthesia. 6) In all groups the systemic complications occurred such as nausea, vomiting, micturition difficulty, itching, constipation, headache and backache. This complications did not appear to be dose dependent and not occurred in patients not receiving morphine. Severe delayed respiratory depression was noted 2 cases in group Ⅲ.