과실이 크고 품질이 우수한 조생종 배 ‘금촌조생’ 육성

조광식(Kwang-Sik Cho1),손동수(Dong-Soo Son),강삼석(Sam-Seok Kang),김명수(Myung-Su Kim),홍경희(Kyung-Hui Hong),윤석규(Seok-Kyu Yun),조강희(Gang-Hui Cho),조현모(Hyeon-Mo Cho) 한국원예학회 2004 원예과학기술지 Vol.22 No.1

‘금촌조생’ 품종은 농촌진흥청 원예연구소 나주배연구소에서 1971년 ‘금촌추’의 품질을 개선하기 위해 당도가 높고 육질이 유연한 ‘단배’를 교배하여 1982년 1차 선발되었고, 1997년부터 5년 간 지역적응시험을 거쳐 2001년 최종 선발 및 품종보호출원 되었다. 수세는 비교적 강하고, 수자는 반개장성이다. 꽃가루가 풍부하며, 주요 재배품종과 교배친화성을 보인다. 또한 흑반병에 대하여 강한 포장저항성을 나타내었다. 숙기는 재배중인 ‘원황’ 품종보다 약 5일 정도 늦은 9월 3일로 추석에 출하하기 알맞은 품종이다. 과형은 ‘금촌추’와 같은 도원추형이고, 과피색은 황갈색이다. 과중은 593g이고, 당도는 13.2Bx이다. 육질은 유연하며 과즙이 풍부하고, 석세포가 없어 식미가 매우 우수하다. 그러나 과육선숙형 품종으로 원예적 수확기에도 과피에 녹색이 남지만, 완숙과가 되면 황갈색으로 착색된다. 상온저장 기간은 20일 정도로 다른 조생종에 비해 저장력은 좋은 편이다. ‘Geumchonjosaeng’ pear cultivar (Pyrus pyrifolia var. culta Nakai) originated from the cross between ‘Imamuraaki’ and ‘Danbae’ to improve the fruit quality of ‘Imamuraaki’ cultivar in 1971 at Naju Pear Research Institute of National Horticultural Research Institute (NHRI), Rural Development Administration (RDA). It was preliminarily selected in 1982 and named in 2001. The tree habit shows vigorous growth and upright spreading. It carries abundant pollen grains and shows cross compatibility with leading cultivars. Also it shows high resistance to black leaf spot (Alternaria kikuchiana) in the field condition. Optimum harvest time is around Sep. 3, which is 5 days later than that of ‘Wonwhang’, and it could satisfy consumer’s demand for high quality pear fruit in “Chuseok”. The obovate fruit shape resembles maternal parent, ‘Imamuraaki’ and skin color is green yellowish brown at normal harvesting time and gradually turned to yellowish brown at full ripennig state. Fruit weighs about 593 g, and the soluble solid content is 13.5 ˚Bx. The flesh is very soft and juicy and, rendering good eating quality. Shelf life is about 20 days under the ambient temperature, and it is a relatively long period as compare with other early season cultivars.

Fosfomycin의 항균효과 및 capillary electrophoresis에 의한 측정법에 관한 연구

윤효인,박승춘,이규승,권진욱,조준형,신광순,김무열,허강준,조명행 충남대학교 수의과대학 동물의과학연구소 1996 動物醫科學硏究誌 Vol.4 No.-

Fosfomycin, a low molecular antibiotic, is to be easily synthesized, therefore to be possibly used in veterinary sectors due to econimic reasons. In this study, we determined the antibacterial activities of fosfomycin against some domestic animal-origin pathogens, and its combined effects with some important antibacterials available. We also compared detection methods of fosfomycin from various measuring instruments. The results obtained through this experiment were as follows: 1. Antibacterial activities of fosfomycin against the pathogens used in this experiment were appeared fairly low. We found the antobacterial activities depanded on the kinds of media and the addition of some material thereins, which suggests the importance of appropriate medium so as to judge the antibacterial activity of fosfomycin. 2. Fosfomycin showed varying antibacterial effects in combination with other antibacterials, which should be taken into consideration when combining other antobacterials especially in the clinical settings. Of the combined antivacterials, fosfomycin had synergistic effects in combination with amoxicillin but antagonistic effects with oxytetracyline. 3. Conventional detection methods using HPLC, GC and spectrophotometer were not appropriate to measure fosfomycin. Capillary electrophoresis by the way of the indirect ultraviolet detection method was good enough to detect fosfomycin in the range of expected concentration in tissues, with the limit of quantitation (LOQ) of 1.25 ㎍/㎖. We recommend the eletrophoresis method could be used to detect fosfomycin, thereby being able to set the optimal dosage for animals and providing the measures in relation with the residual concentration in the meat.

토끼에서 enrofloxacin과 enrofloxacin acetate의 比較藥物動態學

윤효인,박승춘,김창식,김민규,최기섭,신광순,박종일,조준형,조명행 충남대학교 수의과대학 동물의과학연구소 1996 動物醫科學硏究誌 Vol.4 No.-

This study was designed to examine the in vitro antibacterial activities and pharmacokinetics of enrofloxacin acetate (ENFXA) and enrofloxacin (ENFX). Two enrofloxacins had wide spectrum antibacterial activities against Gram positive and negative bacteria, and mycoplasma, showing potent antibacterial activities with low MICs (0.05-3.33 ㎍/㎖ for Gram positives, 0.002 ㎍/㎖ for Gram negatives and 0.02 ㎍/㎖ for mycoplasma). In order to investigate the profiles of two formulations of enrofloxacin we studied comparative pharmacokinetics of them in rabbits. Five rabbits were given 5 ㎎/㎏ body weight of each enrofloxacin formulation intravenously (i.v.) and orally (p.o.) in a cross-over study. Pharmacokinetic parameters of both formulations were calculated by the use of PCNONLIN, a computer program. Their bioavailibility in rabbits, the means of the area under the curve (AUC). After oral administration of each formulation in rabbits, the mean elimination half-lives (t_1/2,ke) were 3.25h (ENFX) and 4.32 h (ENFXA), and mean AUC 4.27 ㎍·h/㎖ (ENFX) and 6.21 ㎍·h/㎖ (ENFXA). Both enrofloxacin formulations seemed to have good tissue distribution and penetration as indicated by large volume of distribution: 4.76 1/㎏ for ENFX and 7.23 1/㎏ for ENFXA. With the results obtained in this study, ENFXA could be used in place of ENFX in rabbits.

급성 뇌경색 환자에서 경색 위치가 심근 효소치 상승에 미치는 영향

윤경호,박현영,박성욱,장혁,김요식,조광호,유남진,김남호,오석규,정진원 圓光大學校 醫科學硏究所 2003 圓光醫科學 Vol.18 No.2

MRI용 초전도 능동차폐 마그네트의 설계에 관한 연구

조윤현,이광호,김성도 東亞大學校 附設 情報通信硏究所 1996 情報通信硏究所論文誌 Vol.4 No.1

An optimal design approach is presented for the high homegeneity superconducting magnet with a superconducting active shield esperically for a magnetic resonance imaging system. This paper is investigated magnetic phenomena for a stray magnetic to get reduction technigues of the unwanted stray magnetic field from the superconducting magnet.

토양으로부터 분리한 곰팡이에 의한 γ-Linolenic Acid 생산

조광연,이철우 한국식품영양학회 1995 韓國食品營養學會誌 Vol.8 No.1

100개의 토양시료로부터 120종의 곰팡이를 분리하여 이 중 GLA 생성능이 가장 우수한 균주를 선발하여 Fusarium 속으로 동정하였다. Fusarium 속이 생산하는 균체량과 지방질 함량은 각각 620㎎/100㎖, 63.5㎎/100㎖ 이었으며 전체 지방산 중 GLA가 차지하는 함량은 약 10.2% 이었다. 120 fungal strains producing γ-linolenic acid(GLA) were isolated from 100 soil samples, and among these, the most suitable one for the production of GLA was identified as Fusarium sp. JK-02. The content of total lipid and dry cell weight was 620㎎/100㎖ and 63.5㎎/100㎖, respectively. The production of GLA was 10.2% of the total fatty acids.

돼지에서 정맥, 근육 그리고 경구 투여시의 enrofloxacin의 약물동태학

윤효인,김무열,박승춘,조준형,박병권,이내경,노상석,장범수,신광순,조명행 충남대학교 수의과대학 동물의과학연구소 1996 動物醫科學硏究誌 Vol.4 No.-

In order to characterize pharmacokinetic profiles according to route of a new enrofloxacin salt form (Enrotil®), it was given to 4 healthy pigs via oral (p.o.), intramuscular (i.m.) or intravenous (i.v.) administrations at a dose rate of 5 ㎎/㎏ body weight. Enrofloxacin (ENFX) in serum was detected by bioassay using E. coli BE1186 as a test organism. The biological elimination half-lives (t_1/2(β)) of ENFX were 6.76±0.99 h (i.v.), 7.16±2.30 h (i.m.) and 11.45±3.90 h (p.o.), Volume of distribution (Vd) of enrofloxacin was 2.20±0.31 L/㎏ (i.v.), 2.52±0.60 L/㎏ (i.m.) and 1.88±0.33 L/㎏ (i.m.). Mean residence time (MRT) was 8.77±1.26 h after i.v. injection and the maximal concentration time (Tmax) following p.o. and i.m. administration was 0.76±0.09 h and 0.60±0.12 h, indicating a rapid absorption from these routes. Bioavailibility (F) was calculated as 64.1% for p.o. administration and 59.71% for i.m. injections. In summary, the newly formulated enrofloxacin salt form has shown a high water solubility, rapid absorption and large tissue distribution, suggesting a potential antibacterials for oral application on a large scale in veterinary sectors.

Box-Wilson 계획법에 의한 沈降炭酸칼슘의 製造條件에 關한 硏究

김영윤,신화우,최광식,안세민,이광표,장영수 원광대학교 식품약품안전성연구소 1993 食品藥品安全性硏究 Vol.6 No.-

Medicinal Precipitated Clacium Carbonate is prepared by the interaction of Calcium Chloride and Ammonium Carbonate Solutions in this study. It has been known that the particle size of Precipitated Calcium Carbonate is greatly affected by the concentration, temperature, and moli-ratio of reactant solutions as well as the temperature at which the precipitate is dried and the temperature of washing water. The purpose of this study is to determine the optimum preparation Condition of medicinal Precipitated Calcium Carbonate. A randomized complete block design wuggested by G.E.P. Box and K.B.Wilson was for this purpose. The optimum preparation condition of light and fine precipitated Calcium Carbonate obtained from this study is as follows : 1) The reacting temperature range is 25∼45℃ 2) The concentration range of reactant solutions is 10∼30% 3) The optimum mole-ratio (CaCl/(NH) CO) is 1.0∼2.0. 4) The drying temperature range is 60∼80℃. 5) Temperature range of washing water is 25∼60℃.

부산·경남지역의 토양오염물질간의 상관도에 관한 연구

주유연,조상원,오광중,손병현 부산대학교 환경문제연구소 1994 環境硏究報 Vol.12 No.-

It appeared over all regions expect common life area that the pollutants level of soil heavy metals in Pusan and kyoung-Nam Province, was higher than the standard on in agriculture area. Especially, Atmosphere and waste area appeared much high and it necessitates monitoring these areas continually. Where we analyzed pollutants level of heavy metals in paddy soils in correspondence with Pusan, Ulsan, and Yangsan region, the order of Pb and Cd concentration were Yangsan 〉 Pusan 〉 Ulsan, the order of Cu and Zn were Yangsan 〉 Ulsan 〉 Pusan, the order of Hg and As were Ulsan 〉 Yangsan 〉 Pusan respectively. It appeared the whole concentration of heavy metals expect Hg and As were the highest ones in Yangsan. So, it was thought that special management should be needed. The analysis of correlation between heavy metals in soil showed that the correlation level between Cd and Pb, Cu and Pb and Zn, Hg and As was high in agricultural area and the correlation level between Zn and Pb, Cd and Hg, Cd and Cu was high but the one between Cd and As was low in atmosphere area. And the correlation between Pb and Cd, Hg and Zn, Hg and Cu was high but the one between Hg and Cu was low in waste area and the correlation level between As and Pb, As and Zn was slightly high but the one between Cd and Cu is low in water area.

排出物診斷에서 "諸病水液 澄澈淸冷 皆屬干寒"의 임상적 價値에 대한 文獻的 考察 : 鼻流, 喀痰, 구토를 중심으로

李光揆,姜昌洙,愈潤朝 대한한의진단학회 1998 大韓韓醫診斷學會誌 Vol.2 No.2

There are many ways to differentiate symptoms and signs in clinic, and among them are the ways to distinguish various symptoms and signs by comparing them without using natural philosophy and chemistry and tools in differentiating cold syndrome or hot syndrome, especially how to make the nature of illness clear by examining various abnormal condition of the secretion or dejecta is very useful in treatment. Here I report some findings about differential diagnosis of cold symptoms through the secretion or dejecta based on "Chebyeongsuaek Chingcheolcheongnaeng Kaesokuhan" of 'The Yellow Emperor's Canon of Internal Medicine·Chijinyodaeron, by literal study on the books about clinic. As a conclusion, the ejection seems to be trifling, but, in fact, it plays very important part in differentiating cold symptoms and hot symptoms. Though a medical examination using natural philosophy and chemistry is important, the ejection itself is much more important because it is very decisive in diagnosis of cold symptoms and hot symptoms.