http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
탁태오,이벽림 江原大學校 産業技術硏究所 2001 産業技術硏究 Vol.21 No.B
The human arm is modeled by three rigid bodies(the upper arm, the forearm and the hand)with seven degree of freedom(three in the shoulder, two in the elbow and two in the wrist). The objective of this work is to present a method to determine the three-dimensional kinematics of the human elbow joint using a magnetic tracking device. Euler angle were used to determine the elbow flexion-extension, and the pronation-supination. The elbow motion for the various driving conditions is measured through the driving test using a simulator. Discomfort levels of elbow joint motions were obtained as discomfort functions, which were based on subjects' perceived discomfort level estimated by magnitude estimation. The results showed that the discomfort posture of elbow joint motions occurred in the driving motion.
대식세포주 RAW264.7에서 Nitric oxide에 의해 과발현되는 CD53의 기능분석
김태림,이혜영,김인규,백상기 충남대학교 생물공학연구소 2004 생물공학연구지 Vol.10 No.2
The CD53 antigen is a member of the tetraspanin membrane protein family that is expressed in the lymphoid-myeloid lineage. It is highly expressed in Radio-resistant tumor cells. Recently, it was reported that CD53 associates with the GSH-metabolizing protein γ-glutamyl transpeptidase. Its biological roles however remains unknown. Macrophages activated by microbial lipopolysaccharides (LPS) produce a burst of nitric oxide and reactive oxygen species. Nitric oxide plays important roles in macrophage activation as a toxic agent towards infectious organisms, an inducer or suppressor of apoptosis or an immunoregulator, whether nitric oxide can induce or inhibit apoptosis is highly dependent on different cell types at different stages of the inflammatory process. Using cDNA microarrays, we identified CD53 as one of the principal genes up-regulated by exposure of macrophages to LPS. We found that mRNA and protein levels of CD53 were increased by nitric oxide as well as LPS treatment in macrophages. Cells stably transfected with sense CD53 cDNA had lower levels of peroxide, and were more resistant to γ-irradiation. The stably transfected RAW264.7 cells with antisense CD53 recombination had the opposite properties. Activation of CD53 by cross-linking with monoclonal anti-CD53 antibody (OX-79) showed the expression of the inducible nitric oxide synthase. We propose that the induction of CD53 is one of major self-protection mechanisms of macrophages against LPS induced-oxidative stress and irradiation.
장태원,김윤규,윤동영,이창희,홍영습,신해림,정갑열,김준연 大韓産業醫學會 2001 대한직업환경의학회지 Vol.13 No.4
Objectives : This study was carried out to suggest preventive methods for hypertension in cold-exposed workers. Methods : In 11 refs·iteration industries, 68 workers working in refrigerated areas more than one time per day were selected as the exposed group, and 68 workers not exposed to cold were selected as the control group. We interviewed the subjects with a questionnaire covering occupational history, and conducted clinical and laboratory tests including measurements of blood pressure and core temperature. Results : The systolic blood pressure in the exposed group(130.0±13.3 mmHg) was significantly higher than that recorded In the control group(118.3±12.1 mmHg), as was the diastolic blood pressure in the exposed group(82.7±8.5 mmHg) versus the control group(77.4±8.7 mmHg). The core temperature in the exposed group(36.1±0.7℃) was significantly lower than that experienced in the control group (36.4±0.5℃). In logistic regression analysis, age, cold exposure severity and milk intake were significant variables, with odds ratios of 5.204(95 % CI 1.440∼18.812), 2.674(95 % CI 1.080∼6.618), and 0.364(95 % Cl 0.141∼0.942) , respectively. Conclusions : Our study suggests that cold-exposed workers have higher a higher risk of hypertension, and that their core temperature is lower. Risk factors affecting hyper-tension of cold-exposed workers include age, cold exposure severity and milk intake. For the prevention of hypertension, cold-exposed workers should minimize cold-exposure time as much as possible.
한동준,임재명,전태성,이현주 江原大學校 産業技術硏究所 1996 産業技術硏究 Vol.16 No.-
This research aims to find granulation and organic removal of the piggery wastewater with the upflow blanket filter (UBF) reactor. UASB process had the effect of high pH on the granulation phase. But teh effect was decreased after the granule formtion. The filter zone of the UBF reactor had the function of GSS and contributed to removing the organic because of its biofilm formtion. The removal rates of total COD and soluble COD were 70% ~ 80% and 60 ~80% at an influent organic loading range of 2 ~ 17.4 kgCOD/m?.d, respectively. The methane production rate with the organic removal was 0.21 ~ 0.34 ℓCH?/gCOD ? and the maximum methan production rate was 0.34 CH?ℓ/gCOD ? at the volumetric loading 5 kgCOD/m?.d.
항진균물질을 생산하는 Streptomyces fimbriatus AF21-3의 분리 및 동정
장주현,김정완,이우윤,윤영준,이경림,김승곤,이태수 인천대학교 2000 基礎科學論文集 Vol.11 No.1
Actinomycetes were isolated from soil to find new antibiotics. An active antimicrobial compound was isolated from the culture filtrate of Actinomycetes AF 21-3. The Actinomycetes strain which showed strong antifungal activity against Candida tropicalis and Microsporum gypseum was identified as Streptomyces fimbriatus and named as Streptomyces fimbriatus AF 21-3.
Propylthiouracil에 의한 중증 급성간염 1예
임종주,심미령,이명수,김태현,오석규,안선호,박무림,김남호,박병현,조성구 圓光大學校 醫科學硏究所 2002 圓光醫科學 Vol.17 No.2
PTU에 의한 간염의 발생은 매우 드물게 발생하는 것으로 알려져 있으나 저자들은 Graves씨 병으로 진단 받고 propylthiouracil 투여를 받고있던 환자에서 중증의 급성 간염이 발생한 1예를 경험하였기에 보고하는 바이다. Propylthiouracil is widely used to treat patients with hyperthyroidism. This drug has been associated with severe hepatotoxicity rarely. We presented the case of jaundice and profound liver dysfunction from a 23-year old woman treated with propylthiouracil for hyperthyroidism. Viral, metabolic, and autoimmune liver disease could be excluded and liver biopsy revealed a pattern of acute hepatitis. After discontinuing the drug, there was a progressive resolution of hepatic symptoms and decrease in biochemical data of the liver. Despite propylthiouracil induced hepatitis in rare case, patients receiving propylthiouracil are exposed to develope severe hepatotoxicity. Therefore it might be advisable to monitor level of the transaminase on regular base from patients receiving propylthiouracil.
Lee, Tae-Rim,Ahn, Jin Mo,Kim, Gyuhee,Kim, Sangsoo Korea Genome Organization 2017 Genomics & informatics Vol.15 No.4
Next-generation sequencing (NGS) technology has become a trend in the genomics research area. There are many software programs and automated pipelines to analyze NGS data, which can ease the pain for traditional scientists who are not familiar with computer programming. However, downstream analyses, such as finding differentially expressed genes or visualizing linkage disequilibrium maps and genome-wide association study (GWAS) data, still remain a challenge. Here, we introduce a dockerized web application written in R using the Shiny platform to visualize pre-analyzed RNA sequencing and GWAS data. In addition, we have integrated a genome browser based on the JBrowse platform and an automated intermediate parsing process required for custom track construction, so that users can easily build and navigate their personal genome tracks with in-house datasets. This application will help scientists perform series of downstream analyses and obtain a more integrative understanding about various types of genomic data by interactively visualizing them with customizable options.
A CLASS OF SERIES INVOLVING THE ZETA FUNCTION
Lee, Hye-Rim,Cho, Young-Joon,Lee, Keum-Sik,Seo, Tae-Young The Youngnam Mathematical Society Korea 2000 East Asian mathematical journal Vol.16 No.2
The authors apply the theory of multiple Gamma functions, which was recently revived in the study of the determinants of the Laplacians, in order to present a class of closed-form evaluations of series involving the Zeta function by appealing only to the definitions of the double and triple Gamma functions.