일부 성인의 치과 공포감 관련 요인

김수경 ( Soo Kyung Kim ),김미희 ( Mi Hee Kim ),최현지 ( Hyun Ji Choi ),황정근 ( Jung Geun Hwang ) 한국치위생학회(구 한국치위생교육학회) 2014 한국치위생학회지 Vol.14 No.6

Objectives: The purpose of the study was to investigate the related factors to dental fear in some adults. Methods: A self-reported questionnaire was filled out by 320 adults in Seoul and Gyeonggi-do from April to June, 2013. Except 14 incomplete answers, data were analyzed by SPSS 18.0 program. The questionnaire consisted of general characteristics of the subjects(7 questions), dental fear related factor(18 questions), distrust for dentist(15 questions), and distrust for dental hygienist(11 questions). The instrument for dental treatment fear was Dental fear Survey(DFS) adapted from Kleinknecht and partly modified by Choi. Out of 20 questions, 18 questions were reconstructed and score by Likert 5 scale. Higher score means higher dental fear. Cronbach alpha was 0.959 in the study. The distrust for dentist and dental hygienist was adapted from Choi and reconstructed and score by Likert 5 scale. Higher score means higher distrust for dentist and dental hygienist. Cronbach alpha was 0.937 in distrust for dentist and 0.874 in distrust for dental hygienist in the study. Results: Those who experienced dental pain tended to have dental fear. The reasons for dental fear were as follows; bad breath(2.96 out of 5 points, hereafter represented as of 2.96/5), dental caries(2.88/5), missing teeth(2.87/5) and tooth pain(2.77/5). The distrust for the dentist was the main dental fear in the adults. Conclusions: The dental fear was closely related to gender, experience of dental pain, oral symptoms and distrust for the dentist. As the psychological pain in the patients was mainly influenced by the trustful atmosphere, it is necessary to make the patient easy before treatment.

흰쥐에서 가시오가피 발효물의 단회 및 반복투여 독성평가

조주현(Ju-Hyun Cho),박인재(In-Jae Park),백순옥(Soon-Ok Baik),최수영(Soo-Young Choi),최구희(Goo-Hee Choi) 한국식품과학회 2014 한국식품과학회지 Vol.46 No.2

본 연구에서는 사용된 가시오가피 영지버섯 발효물과 가시오가피 상황버섯 발효물에 대한 열수추출물을 최고 2 g/kg의 농도로 단회 투여한 SD-rats에 체중 변화, 임상증상 등에서 어떠한 독성도 관찰할 수 없었으며, 1 g/kg 이하의 농도로 4주간 반복 투여한 SD-rats에서도 체중변화, 임상증상, 장기 무게, 혈액학적 성상, 혈액생화학적 성상 등에서 어떠한 독성과 비정상적인 소견을 관찰할 수 없었다. 따라서, 본 연구의 결과로 볼 때 가시오가피 영지버섯 발효물 열수추출물(FM-5111)과 가시오가피 상황버섯 발효물 열수추출물(FM-5131)은 본 연구에서 사용한 농도 내에서의 안전성을 확인할 수 있었다. 황 함유 아미노산의 결핍은 여러 가지 간질환 등의 증상을 야기한다(27). 또한, Choi와 Ahn(28)은 오가피 부위별 50% (v/v) 메탄올 추출액의 전자공여능은 줄기 추출물에서 90.21%, 뿌리 추출물에서 85.71%로 높은 활성을 보고하여 오가피의 항산화능을 규명하였다. 따라서, 본 연구에 사용된 시료 또한 항산화능과 같은 기능성을 가질것으로 사료되며, 추가 연구로 아미노산 분석을 통해 황 함유 아미노산의 함량 변화를 분석하고 간 기능 개선 효능을 평가하여 안전성이 확보된 기능성 식품소재 개발 연구를 진행할 계획이다. In this study, the products of Acanthopanax senticosus fermentation were derived from the mycelia of 2 mushrooms, Ganoderma lucidum and Phellinus linteus, to determine their safety in Sprague-Dawley rats. Rats were orally administered the water extracts of A. senticosus fermentation products with G. lucidum (FM-5111) or P. linteus (FM-5131) at dose levels of 0.5, 1.0, or 2.0 g/kg for the single-dose toxicity test and 0.25, 0.5, or 1.0 g/kg for the repeated-dose toxicity test. There were no significant differences in body weight gain, feed intake, or water consumption between control and FM-5111- or FM-5131-treated rats. Hematological and blood biochemistry analysis revealed that none of the investigated parameters were affected by the A. senticosus fermentation products, and no remarkable lesions were observed upon histopathological analysis. We conclude that the A. senticosus fermentation products obtained from mushroom mycelia are safe for long-term administration and could be considered as multi-functional nutrients for the improvement of liver function and immunity.

관상동맥 질환에서 CD14 유전자형에 따른 세균 및 Heat Shock Protein에 대한 반응의 차이

한주용,최수연,조현주,김화평,강현재,구본권,김남중,김효수,손대원,오병희,박영배,최윤식 대한감염학회 2007 감염과 화학요법 Vol.39 No.1

Background : CD14 is the receptor for lipopolysaccharides and heat shock protein (HSP), which has been suggested being associated with increased risk of coronary artery disease (CAD). We investigated whether the response to infectious agents or HSP is different according to CD14 polymorphism in Koreans. Materials and Methods : Antibody titers to Helicobacter pylori, Chlamydia pneumoniae, and human HSP60 (hHSP60) were measured in 48 patients with stable CAD and in 41 healthy controls by ELISA. CD14 genotype was determined by PCR and high-sensitivity C-reactive protein (hs-CRP) was measured. Results : Seropositivity to C. pneumoniae and H. pylori, and antibody titer to hHSP60 were not significantly associated with the presence of CAD. CD14 genotype distribution was 31 TT (35%), 43 CT (48%), and 15 CC (17%). To compare the response to the infectious organism and hHSP60, we divided study population into 3 groups; CAD patients with non-TT genotype (group I, n=30), CAD patients with TT genotype (group II, n=18), and normal controls (group III, n=41). Seropositivity to C. pneumoniae and H. pylori, and antibody titer to hHSP60 were not significantly different among 3 groups. Though hs-CRP level was significantly different among 3 groups, post-Hoc analysis showed that hs-CRP level was not significantly different between group I and group II (group I: 1.6[1.1-3.5] mg/L and group II: 0.35[0.1-2.0] mg/L). Conclusions : This study suggests that the inflammatory responses to infectious organisms and HSP do not differ according to the CD14 genotype in Koreans. 목적 : 만성적인 세균 감염이나 자가 면역 반응이 동맥경화와 연관되어 있다는 주장이 제기되어 왔다. CD14은 lipopolysaccharides (LPS)와 heat shock protein(HSP)의 수용체로 C(-260)→T 다형성이 관상동맥 질환의 위험과 관련되어 있다고 제안되어 왔다. 본 연구에서는 한국인에서 CD14 다형성에 따른 LPS와 HSP에 대한 반응성을 염증표지자를 측정하여 살펴보고자 하였다. 재료 및 방법 : 안정형 관상동맥 환자 48명과 정상 대조군 41명을 대상으로 Chlamydia pneumoniae, Helicobacter pylori 항체 및 인체 HSP60 (hHSP60) 항체 역가를 enzyme-linked immunosorbent assay (ELISA) 방법으로 측정하였다. CD14 유전자형은 중합효소연쇄반응을 이용하여 결정하였고 hs-CRP를 측정하였다. 결과 : C. pneumonias 및 H. pylori 항체 양성 여부 및 항체 역가, 그리고 hHSP60에 대한 항체 역가는 안정형 관상동맥 질환의 유무와 유의한 상관관계는 없었다. CD14 유전자형의 분포는 TT 30명(39%), CT 31명(40%), 그리고 CC 16명(21%)이었다. 관상동맥 질환 군에서 TT 유전자형은 38%, 대조군에서는 32%로 TT 유전자형과 관상동맥 질환의 유무와는 유의한 상관관계가 발견되지 않았다(P>0.05). CD14 유전자형에 따라 C. pneumonias와 H.pylori 감염 및 hHSP60에 따른 반응에 차이가 있는지 여 부를 알아보기 위해, 관상동맥 질환 군을 다시 TT 유전자형 군과 non-TT 유전자형 군으로 나누어, 전체적으로 세군에서 항체 양성률과 역가를 비교하였다(I군: CD14 TT 유전자형을 가진 안정형 관상동맥 환자, II군: CD14 TT 유전자형을 가진 안정형 관상동맥 환자, III군: 정상 대조군). 세 군에서 C. pneumonias와 H. pylori 항체 양성률 및 hHSP60 항체 역가에는 유의한 차이가 없었다. 세 군사이에 hs-CRP 값에 유의한 차이가 있었지만, post-Hoc분석에서 II군의 hs-CRP 값이 I군에 비해 유의하게 높지는 않았다(0.35 [0.1-2.0] mg/L in group II vs. 1.6 [1.1-3.5]mg/L in group I, P>0.05). 결론 : 본 연구는 한국인에서 CD14 유전자형에 따라 LPS나 HSP에 대한 반응이 유의하게 다르지 않음을 시사한다.

최근 10년간 원광의대병원에서 시행한 소아 심장혈관 수술의 임상적 고찰

윤향석,정수미,최두영,오광수,오연균,김종덕,양현웅,이삼윤,김형곤,최종범,최순호,노병석 圓光大學校 醫科學硏究所 1995 圓光醫科學 Vol.11 No.2

We reviewed 10 years experiences of the clinical aspects and early postoperative results in 544 pediatric patients(age less than 16 years old). Among them. 529 cases had the congenital heart diseases, and 15 had the acquired diseases. Open heart surgery was performed in 413 patients. 115 cases were treated with non-open heart surgery. 16 with interventional catheterization. Annual increase of the cardiac patients was not significant in recent 10 years, except slight increase in 1994. The mean age of the study patients had been evidently changed to younger year by year. Total mortality rate of the open heart surgery was 6.4%. The cyanotic congenital heart diseases were high in early postoperative mortality by 25.7%, whereas 4% in acyanotic group. The age group less than one month was most highest in surgical mortality(66.7%). There were no deaths in patients with patent ductus arteriosus(103 cases), atrial septal defect(83 cases) or pulmonary stenosis(17 cases). Among 220 patients with ventricular septal defects(VSD). 10(4.5%) were died early postoperatively. In cyanotic group, the patients with pulmonary atresia with ventricular septal defects(PAVSD), transposition of the great arteries(TGA), interrupted aortic arch(IAA), complex cardiac anomalies with isomerism seemed to be most susceptible to an early death.

캡슐화된 잠열 미립자 슬러리를 열 매체로 하는 축열식 냉방시스템

최준규,이재구,양현수,주태운,김필수 한국공업화학회 2003 응용화학 Vol.7 No.1

Microcapsules containing tetradecane as the phase change material (PCM) and ashell of meolamine-formalin resin were prepared by in situ polymerization. Tooptimize the encapsulation process, experiments were performed under various reaction conditions. Microcapsules with a high uniformity could be prepared, and the ratio of breakage of the microcapsules was less than 6% over 10,000 cycles using by a circulation pump. The cooling system, which has adopted MPCM slurry as a media for transporting cold thermal energy, is designed to investigate the performance of newly developed coolant. The discharging times of cold energy in circulating 20 wt% MPCM slurry are lasted to 260 minutes as long as the sensible cooling system. According, it was demonstrated that the microcapsules prepared in the current research are suitable for potential application as hat transporting media.

液體膜에 의한 Cyclohexane과 n-Heptane 混合物의 分離에 있어서 界面活性劑가 미치는 影響

崔洙鉉,鄭泰秀 成均館大學校 科學技術硏究所 1994 論文集 Vol.45 No.2

In the separation of cyclohexane-n-heptane mixture by liquid membrane in a batch system, the effects of surfactants on the separation factor were investigated with the surfactant concentration ranging from 0.2 to 1.0wt%. The surfactants used were sodium lauryl sulfate, sodium laurylether sulfate and triethanolamine lauryl sulfate. The separation was most effective at the surfactant concentration of 0.4wt% and at the emulsification speed of 1200 rpm for all three surfactants. The separation was also most effective at the contact time of 20 mimutes for sodiurn lauryl sulfate and 15 minutes for sodium laurylether sulfate at the settling time of 10 minutes, while it was so for triethanolamine lauryl sulfate at the contact time of 20 minutes and the settling time of 15 minutes.

방사선조사가 백서 법량질형성 과정에 미치는 영향에 관한 연구

최순철,유동수,최현배,박태원 大韓口腔顎顔面 放射線學會 1997 Imaging Science in Dentistry Vol.27 No.1

The purpose of this study was to investigate the radiation effect on the stages of amelogenesis. Twenty 11-day-old rats which were irradiated by 4Gy of gamma radiation on the 19th prenatal day were used for the experimental group and twenty 11-day-old rats which were not irradiated were used for the control group. The length of each zone of amelogenesis were measured on the sagittal section using a light microscopic enlargement at 400 x the normal view while the morphologic changes of ameloblasts of each zone were observed electron-microscopically. The obtained results were as followed: 1. The length of the region of facing pulp and facing dentin of the zone of presecretion were increased by 11.5%(p<0.05) and 17.7%(p<0.01), respectively. 2. The length of the zone of secretion was increased by 17.3%(p<0.01), but the zone of maturation was decreased by 15.3%(p<0.01). 3. The total length of the zone of amelogenesis was not changed significantly(p>0.05). 4. Electron-microscopically, enlargement of the cell membrane, rER, mitochondria, and nuclear membrane were observed. These changes were mostly severe in the zone of maturation.

文民政府時期의 老人福祉서비스에 관한 硏究

崔昌茂,高洙玄 韓國福祉行政學會 2002 복지행정논총 Vol.12 No.1

본 논문은 우리나라의 김영삼 정부시기 동안의 사회복지서비스정책 중 노인복지서비스부문을 분석한 것이다. 김영삼 정부는 3당 합당과정을 통하여 탄생한 정권이지만 노태우 정부와는 달리 민선 민간정부라는 특징을 가지고 있었고 이른바 '문민정부'라는 정치적 정당성도 확보하고 있었던 시기에 해당한다. 노태우 정부가 민선 군사정부였음에 비추어 군사정권이 종식되었다는 상징적인 의미를 내포하고 있는 것이다. 그러나 문민정부시기는 1990년대 후반에 해당하는 시기로서 국내외적으로 경기침체기에 접어든 시기였고 1990년대 전반에 비하여 시민사회나 정치사회 등 사회복지환경에서도 복지확대를 위한 활동이 두드러지지 못했던 시기에 해당한다. 이러한 사회복지의 외재적 요인은 사회복지 내용에도 영향을 미쳐 제6공화국 출범 이후 복지팽창기를 누려왔던 시기가 지속적 이행을 하지 못하고 침체기로 접어들게 하였다. 노태우 정부가 공공부조나 사회보험정책의 확대를 통하여 사회통합과 정치적 정당성 확보에 목적을 둔 것에 비하여 문민정부는 비교적 재정 수요가 적은 사회복지서비스분야를 중심으로 복지정책을 구가한 것이다. 상징적으로는 '삶의 질 세계화'를 주창하였지만 오히려 복지다원주의적 복지이념을 보였고 사회복지서비스 역시 수익자부담 원칙이나 사적자치의 원리를 적용하려는 기조를 나타내고 있다. 노인복지서비스 역시 재가복지의 이념을 강조하거나 유료 노인 복지시설의 허용을 통하여 민간전달체계의 길을 열었다는 평가의 이면에는 국가복지의 축소라는 비판이 있을 수도 있다. 노인복지서비스의 대상자인 노인 인구 면에서도 이시기에는 고령화사회에 다가서는 전체인구의 6% 수준에 있었고 노인인구 급증에 따른 정책적 대응이 필요한 시점에 있었음에도 이에 대한 구체적인 정책수립이 이루어지지 못하였다. 현대 사회복지정책의 이념이 빈곤과 사회적 일탈자의 치유라는 사후 처방적 대처보다는 변화하는 사회적 상황에 대응한 예방적 복지조치의 비중이 높아져야한다는 관점에서 본다면 인구 고령화에 대비한 노인복지서비스정책의 확충의 중요성은 시사하는 바가 크다.

SM 45C강과 SS 41강의 미세조직과 파괴인성

최기순,김현철,임병수 成均館大學校 科學技術硏究所 1997 論文集 Vol.48 No.1

The effect of microstructure on fracture toughness of SM 45C steel and SS 41 steel has been investigated. Values of fracture toughness were measured in, each specimen of different microstructure and the investigation was carried out to find out the relationship between fracture toughness and microstructure. Fracture toughness increases with increasing grain size and spacing of the second phase(Fe_3C) particles in SM 45C. Strength ratio and toughness increased with increasing grain size and spacing of the second phase(Fe_3C) particles in SS 41 steel.

열화콘크리트 폐기물의 재생시멘트 활용방안에 관한 기초적 연구

최현수,안재철,강병희 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.2(구조계)

The purpose of this study is development of technique to use cementitious powder as recycle cement produced from deteriorated Concrete waste which has a large quantity of calcium carbonate. Therefore, after having theoretical consideration based on the properties of high-heated concrete and concerning about neutralization of Concrete, we analysis chemical properties of ingredients of cementitious powder. After making origin cement paste, then processing the accelarated carbonation, we consider the properties of hydration and chemical properties of cementitious powder under various temperature conditions. As a result of the thermal analysis, the CaCO₃content of cementitious powder would affect decision of heat temperature to recover its hydrated ability because CaCO₃content is increased when neutralization is progressed. And as a result of XRD analysis, in case of origin powder of non-neutralized paste, CaO peak is found at 700℃. but, heat temperature to generate CaO would increase when the content of neutralized ingredients is increased. Finally, recycle cement heated at 700℃ shows the best compressive strength when the content of neutralized ingredients in recycle cement is less then 50%. However, it would be quite difficult to manage quality of recycle cement according to recycling points of various concrete waste.