도장작업시 유해인자들의 노출수준과 작업환경관리실태

이세기,문덕환,이채관,황용식,선병관,손병철,김대환,이창희,김휘동,이채언 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.5

Objectives: For the purpose of preparing the fundamental data and assessing the status of exposure level of chemical substances in painting process. Methods and Materials: The author determined the concentration of organic solvents, lead(Pb), Chromium(Cr), and Toluene-2, 4-diisocyanate(TDI) in air of painting process to 90 industries classified by 15 types of manufacturing industry during a period from Jan. 1st 2001 to Dec. 31st 2001. Results: The results were as follows: 1. The geometric mean level of each chemical substance was 0.1706 ppm for exposure index in organic solvents, 0.0019㎎/㎥ for Pb, 0.0024 ㎎/㎥ for Cr, and 0.0004ppm for TDI, respectively. 2. The exposure level of each chemical substances by type of painting was the highest in dipping and brush painting for organic solvent, in spray-painting for TDI, and in spray gun-painting for Pb and Cr, respectively. 3. The exposure level of each chemical substances by type of local ventilation equipment was higher in enclosed and booth type for organic solvents. Cr, and TDI, and in exterior type for Pb, respectively than those of other types. 4. The exposure level of each chemical substances by type of hazardous material arresting media was higher in using water for organic substances, in using bag filter for Pb, TDI, respectively than those of other types. Conclusion: According to above results, this study suggests that the exposure level by type of industry exceeded the exposure level in wooden furniture and metal furniture manufacturing industry for organic solvents and Pb, respectively.

부산지역 강하먼지 중 불용성 중금속 함유량

이용범,황용식,이창희,박명희,이채관,강동묵,김정원,전병일,문덕환 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.1

■ Objectives The purpose of this study was to estimate qualitatively various bulk deposition flux of insoluble heavy metal components by applying regional and seasonal distribution. our institution from January 1980 to December 31th, 2001. ■ Materials and Methods Dustfall particles were collected by the modified American dust jar (wide inlet bottle type) at 6 sampling sites in Pusan area from March, 1999 to February, 2000. Five chemical species (Cd, Cr, Mn, Ni and Pb) were analyzed by AAS(Perkin-Elmer 4100ZL). ■ Results The mean values of each heavy metal concentrations were Cd for 3.947 g/㎢/month, Cr for 0.191 ㎏/㎢/month, Mn for 0.375 ㎏/㎢/month, Ni for 0.176 ㎏/㎢/month, and Pb for 0.823 ㎏/㎢/month. ■ Conclusions Insoluble heavy metal amount of regional variations were found in order of industrial zone, coastal zone, commercial zone, agricultural zone and residential zone.

신경회로망에 웨이브렛 함수를 이용한 새로운 지능제어방식

이용구,이승형,이현관,엄기환 동국대학교 대학원 1997 大學院硏究論集-東國大學校 大學院 Vol.27 No.-

In this paper, we propose the hybrid system identification model and control method using neural networks. Proposed control method performs, for a nonlinear plant with unknown functions, system identification using an adaptive wavelet in a neural network, and then a nonlinear controller is designed with those identified informations. To identify a nonlinear function, which is not directly related to input signals, we can use an adaptive wavelet in three-layed neural network. In order to verify the usefulness of the proposed method, we simulate the proposed control method with cart pole system.

백혈병 세포중 대한(±)-ar-Turmerone, 자근 및 황금추출물에 의한 항암제의 세포독성 증강효과

이윤영,유관희,김삼용,안병준 충남대학교 암연구소 1991 癌共同硏究所 硏究誌 Vol.1 No.1

Using the colorimetric [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] (MTT)assay, we evaluated the chemosensitivity of 8 anticancer drugs{vincristine(VCR), vinblastine (VBL), adriamycin(ADR), cisplatin(CPDD), etoposide(VP-16), cytosine arabinoside(ara-C), bleomycin (Bleo) and cyclophosphamide(CYC)} and the cytotoxicity-enhancing effects of (±)-ar-turmerone and the extracts of the crude drugs {Lithospermum erythrorhizon(LE) and Scutellaria baicalensis (SB)} on the above mentioned anticancer drugs against HL-60 and KG-1 cells among 8 anticancer drugs, VCR, VBL, ADR, and CPDD inhibited the growth of both cell lines by more than 50%, while VP-16, ara-C, Bleo, and CYC were less effective. (±)-ar-Turmerone had significant inhibitory effects against both cell lines, showing the ID_(50) values of 11.730 μg/ml and 0.292 μg/ml for HL-60 and KG-1 cells, respectively. But the extracts of LE and SB roots showed no significant cytotoxic effects. According to ID_(50) values, the cytotoxicities of VCR, VBL and ADR against HL-60 were enhanced two, eight and three times by mixing (±)-ar-turmerone, five, seven and three times by adding the extract of LE root, and twenty, six and three times by mixing the extract of SB root, respectively. The cytotoxicities of the above mentioned drugs against KG-1 cell were enhanced two, seven and three times by mixing (±)-ar-turmerone, two, three and three times by combining wilth the extract of LB root, and two, five and two times by adding the extract of SB root, respectively. The cytotoxicity-potentiating effects of (±)-ar-turmerone and the extracts of LE and SB roots against HL-60 cell were greater than KG-1 cell.

中, 長距離 選手의 體溫, 脈搏 變化가 記錄에 미치는 影響

李容寬,김종인 公州大學校스포츠科學硏究所 1999 스포츠科學硏究所論文集 Vol.- No.13

We measured how the temperature and the pulse change effects the middle and long distance racer's record with 5 high school athletes and 5 college athletes. The conclusion is as follows : 1. The temperature change by cross country appeared 35.79±0.23 after arise and the others were normal temperature and some concerned with this was appeared an intending level difference of P〈0.05. 2. The pulse change by cross country appeared high 136±9.94 after tough exercise and at this proof it appeared an intending difference of P〈0.05. 3. The temperature change by different ways at the fields seems to change by sweat following the outdoor surroundings and at this proof it appeared difference of P〈0.05 4. The pulse change by different ways at the fields is appeared to be 136.58±19.1 less changed than cross country and at this proof it appeared an intending difference of P〈0.05. 5. The temperature and pulse change after games and tough exercise which is compared with that after cross country and exercises at the fields appeared an intending difference of P〈0.01 at r=0.30 concerned. And at the field of r=0.51 there was a certain concerning and it appeared an intending difference of P〈0.01. After 3 minutes rest, there was a certain concerning of r=0.40 and an intending difference of P〈0.01 at cross country. At the fields, the certain concerning of r=0.61 seemed effect the records and it appeared an intending difference of P〈0.01.

백혈병 세포주에 대한 (±)-ar-Turmerone, 자근 및 황금추출물에 의한 항암제의 세포독성 증강효과

이윤영,유관희,김삼용,안병준 충남대학교부설 생명공학연구소 1992 생물공학연구지 Vol.2 No.-

Using the colorimetric [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide](MTT)assay, we evaluated the chemosensitivity of 8 anticancer drugs{vincristine(VCR), vinblastine(VBL), adriamycin(ADR), cisplatin(CPDD), etoposide(VP-16), cytosine arabinoside(ara-C), bleomycin(Bleo) and cyclophosphamide(CYC)} and the cytotoxicity-enhancing effects of (±)-ar-turmerone and the extracts of the crude drugs {Lithospermum erythrorhizon(LE) and Scutellaria baicalensis(SB)}on the above mentioned anticancer drugs against HL-60 and KG-1 cells among 8 anticancer drugs, VCR, VBL, ADR, and CPDD inhibited the growth of both cell lines by more than 50% while VP-16, ara-C, Bleo, and CYC were less effective. (±)-ar-Turmerone had significant inhibitory effects against both cell lines, showing the ID_50 values of 11.730 ㎍/㎖ and 0.292 ㎍/㎖ for HL-60 and KG-1 cells. respectively. But the extracts of LE and SB roots showed no significant cytotoxic effects. According to ID_50 values, the cytotoxicities of VCR, VBL and ADR against HL-60 were enhanced two, eight and three times by mixing (±)-ar-turmerone, five, seven and three times by adding the extract of LE root, and twenty, six and three times by mixing the extract of SB root, respectively. The cytotoxicities of the above mentioned drugs against KG-1 cell were enhanced two, seven and three times by mixing (±)-ar-turmerone, two, three and three times by conbining wilth the extract of LB root, and two, five and two times by adding the extract of SB root, respectively. The cytotoxicity-potentiating effects of (±)-ar-turmerone and the extracts of LE and SB roots against HL-60 cell were greater than KG-1 cell.

평행봉 Upward kip동작의 역학적 분석

李勇仁,權光善,權五奭 忠南大學校體育科學硏究所 1986 體育科學硏究誌 Vol.4 No.1

As upward kip motion is the basic motion on parallel bars, it is easily trained in the classes of physical education. The purpose of this study is to offer some useful data for teaching and improve the skill of upward kip motion . For this study, two members of the national team and a high-class male player in University were sampled at random. their motion was photographed with 16mm movie camera(48frames/sec) and the gravitational censer of the body was searched for through the drawing figure method. Upward kip motion was divided into 3 phases. And then the movement of the center gravity and the angle change of joint were analyzed and compared with mechanical method. The conclusions are as follows : 1. In phase 1, when kipping legs form an angle of 90 degrees with the parallel bars, the moving speed of center gravity on Subject A was 2.4 m/sec. that of Subject B 2.1 m/sec. that of Subject C 2.4m/sec. As we have seen, Subject A and C were of the same speed. and Subjects B was 0.3m/sec later than Subject A and B, so that I think that the moving speed of the conter gravity must be fast. 2. In phase 2. when the legs are in parallel with the parallel bars. hip joint angle of Subject A was Flex 151° degrees. Subject B Flex 136degrees, Subject C Flex 144 degrees. There fore I think that the legs must extend extend the most. 3. In phase 3, when the motion was perfected, elbow joint angle of Subject A in the last frame was Flex 178degrees, Subject B Flex 170 degrees, Subject C Flex 177degrees. Subject B was shown unstable motion because flexed more than Subject A and B . 4. The perfection of the upward kip motion in the parallel bars depend on the moving speed of body gravity when the kipping legs form an angle of W decrees with the parallel bars. the size of elbows angle. hip angle. and shoulder angle when the legs are in parallel . flexion and extention of elbow joint when the motion was finished, and the waste of the P. and F.

抗癌丹을 投與한 大腸癌 患者 83例에 대한 臨床報告

이용연,서상훈,유화승,최우진,조정효,이연월,손창규,조종관 대한한방종양학회 2000 대한한방종양학회지 Vol.6 No.1

Climical studies were carried out 83 cases of patients with colorectal cancer treated bv Hangamdan(抗癌丹) from January lth 1998 to September 30th 2000. The results were summarized as follows; 1. Distribution of those attached by colorectal cancer, by sex, showed that Male is more then Female, by age, showed that the numbber of fifties is majorith. 2. distribution of diagnostic stage, in descending order; stage Ⅲ(53%, top), stagew Ⅵ(45.8%). 3. The effects of maintenance and improvement in the symptoms with traditional oriental therapy(83.3%) and combined treatment of westem and oriental therapy(92.1%)were boserved. The effects of the symptoms were as folows: diarrhea(37.3%),abdominal pain (25.3%), general body weakness(22.9%), nausea(20.5%) and etc. in orders. 4. Analysis of hematology attached by colorectal cancer, maintenance and increasing of WBC(89.9%), RBC(74.7%), Hgb(81.1%), Platelet(92.4%) were Observed. After taken Hangamdan, the satety of the liver and kidney were as follows; maintenance and decreasting of AST(85.9%), ALT(94.8%) , GTP(87.5%), Creatinine(90.9%) were observed. 5. of IL-12 and IFN-λ attached by colorectal cancer, increasing of IL-12(53.3%), IFN-λ(80%) were observedl. 6. Analysis of QOL attached by colorectal cancer, maintenance and improvement of combined treatment of western and oniental therapy(89.6%), traditional oriental therapy(83.3%) were observed. 7. Analysis of survival in patients with Ⅳ stage of colorectal cancer, above 7 months(18.4%), 12 months(65.8%). 8. Analysis of antitumor effects, maintenance of traditional oriental therapy(83.3%) and maintenance and improvement of combined treatment of western and oriental therapy(80.5%) were observed. Analysis of tumor marker attached by colorectal cancer, maintenance and decreasing of CEA(78.8%) were boserved 9. Analysis of curative valuation, maintenance and improvement of traditional oriental therapy(83.3%), combined treatment of westem and oriental therapy(72.7%) were observed.

Twelfth Night연구

李龍官 水原大學校 1995 論文集 Vol.13 No.-

In Twelfth Night, when Malvolio refuses to be reconciled with the others and goes off claiming, “I'll be revenged on the whole pack of you,” the union of the lovers in the mainplot gets suspended. For, on the literal level, the feminine attire by which Viola can resume her identity falls into Malvolio's hand. On the symbolic level, moreover, Malvolio personifies the “self-ignorance” of the lovers; so his blunt exit insinuates that the lovers have not yet reached “self-knowledge.” His alienation mars the comic resolution and makes Twelfth Night closer to “problem comedies” rather than to “early comedies”.

農村의 母子保健 및 영유아 死亡에 관한 硏究

李性寬,金容達 慶北大學校 醫科大學 1981 慶北醫大誌 Vol.22 No.1

The present study was conducted to investigate the status of maternal and chiid health and infant mortality rate on 2,153 pregnant women registered at health center and their infants from July 1977 to December 1979 in Gun-Wee Gun, Kyungpook Province. The results obtained are as follows; In the socio-demographic risk groups of the registered women in the past, 12 percent were over 35 years old, 11.4 percent experienced more than 5 times of child-bearing among all women and 50 percent of over 35 year old women experienced more than 5 times of child-bearing. 30 percent of pregnant women were registered within the first trimester. 17.5 percent of risk factors was identified during the period of prenatal care, and 6.5% of the factors was found at the first consultation. 17 percent of the women received 5 times of pre-natal care, and average number of visits was 3. During delivery, 27.3 percent were attended by professional attendants and the rest were done by the members of their family. Sterilized delivery kit was used at the high level of 92.7 percent. Abnormal presentation and abnormal placenta led to difficult delivery account for 21.7 percent. B.C.G. vaccination given within a year revealed 70 percent, and only 6.7 percent were properly given within 1 month. D.P.T and polio vaccination given in proper time revealed 20%, and the rate of complete vaccination showed 40 percent. Infant mortality rate was 47.6 percent. In the death causes, 60 percent were unknown, and the death causes which were confirmed were almost preventable. In infant deaths, neonatal deaths account for 82.1 percent. In neonatal deaths, hebdomadal deaths account for 63.1 percent and the deaths on the birth day were 47 percent. The rate of infant mortality was inceased with the age of pregnant women and the numbers of parity, and it decreased with the educational levels.