황색포도구균의 균혈증에서 초기 항생제 치료가 예후에 미치는 영향

김성한,박완범,이기덕,강철인,최영주,김홍빈,박상원,김의석,오명돈,김의종,최강원 대한감염학회 2002 감염 Vol.34 No.5

중학생의 그래프 능력과 논리적 사고력 및 과학 탐구 능력의 관계

김태선,배덕진,김범기 한국과학교육학회 2002 한국과학교육학회지 Vol.22 No.4

본 연구의 목적은 그래프를 작성하고 해석할 수 있는 중학생의 능력을 알아보고, 그래프 능력과 논리적 사고력 및 과학 탐구 능력의 관련성을 분석하여 효과적인 수업전략과 교사의 교수 행동에 대한 시사점을 얻는 데 있다. 중학생 481명을 대상으로 그래프 능력검사지를 이용하여 중학생의 그래프 능력을 알아보고, 논리적 사고력 검사지와 과학 탐구 능력 검사지를 이용하여 그래프 능력과 논리적 사고력 및 과학 탐구 능력의 상관관계를 조사하였다. 그래프 능력과 논리적 사고력 및 과학 탐구 능력의 상관관계를 조사한 결과, 변인 통제 논리와 비례 논리가 그래프 능력과 관련이 깊은 것으로 나타났다. 그리고 그래프 능력은 논리적 사고력 및 과학 탐구 능력과 대부분 유의한 정적 상관을 보이지만, 통계적으로 상관은 낮았다. 이러한 연구 결과에 비추어볼 때, 앞으로 과학 교사는 중학생의 그래프 능력을 향상시키기 위해 그래프의 중요성을 인식하고, 학생들이 그래프를 작성하고 해석할 수 있는 능력과 변인 통제 논리, 비례 논리 등 논리적 사고력을 향상시킬 수 있도록 체계적인 노력과 효과적인 수업전략이 필요하다고 본다. The purpose of this study was to investigate the relationships of graphing abilities to logical thinking and science process skills of middle school students. The subjects for this study were selected 481 students form four middle schools for TOGS(the Test of Graphing in Science), GALT(Group Assessment of Logical Thinking) and TIPSⅡ(Test of integrated Process Skills). This study shows that the correlation coefficient between abilities of students to construct/interpret graphs and the logical thinking was 0.45, and the correlation coefficient between abilities to construct/interpret graphs and science process skills are 0.32. As a result, abilities of students to construct and interpret graphs are more correlate the logical thinking than science process skills.

高麗後期의 宗室封君制

金基德 건국대학교 사학회 1993 建大史學 Vol.8 No.-

三國時期 中國諸王朝에서 賜與된 國王封盞에 관한 檢討

金基德 건국대학교 1989 論文集 Vol.29 No.2

도덕성을 지향한 과학교육의 정의적 접근

김기덕,윤세중 공주대학교 사범대학 과학교육연구소 1998 과학교육연구 Vol.29 No.1

과학의 발달은 인간 생활의 물질적 풍요와 생활의 편리함등 매우 긍정적인 기여를 해왔다. 그럼에도 불구하고 과학기술의 발달과 산업화 과정에서 발생된 공해 문제, 무절제한 대량 소비로 인한 자원의 고갈 및 환경 오염으로 인하여 지구는 황폐해졌다. 또한 가치관의 혼란으로 인한 인간성의 상실을 초래하게 되었다. 환경의 파괴와 인간성의 상실은 인간의 생존을 위협하고 있다. 자연의 질서는 인간의 잘못된 생각과 행동으로 파괴되고 그 결과 또한 인간에게 되돌려지기 때문이다. 이러한 부정적인 측면을 최소화하거나 해결하기 위하여 자연의 법칙에 따르는 도덕성을 강조하는 의식 개혁에 초점을 맞추는 수업이 이루어져야 할 것이다. 과학이 자연 속에서 객관적인 법칙을 찾아 자연의 이치를 밝히는데서 생겨났듯이 도덕 또한 자연 속에서 모태되었기 때문이다. 그러므로 과학은 자연이 인간에게 가르쳐 주는 길을 찾아 실천하고 또한 서로 보충하고 보완해야 할 것이다. 이렇게 함으로써 과학을 통하여 자연의 본질과 질서를 알고 자연의 법칙에 따라 생활하면 과학의 발전으로 인하여 발생된 여러 가지 부정적인 것을 최소화하거나 개선할 수 있으리라 믿는다. 따라서 본 연구는 도덕성을 지향한 과학 교육의 정의적 접근을 위하여, 자연의 법칙을 올바로 이해하고 이치를 깨달음으로써 해결될 수 있도록 중2 과정을 중심으로 지도안을 제시하였다. Scientific progress has had a remarkable impact on the items we use in our daily lives. In our rush for increased convenience and improved life styles the earth is being systematically destroyed. As we move into the 21st century out air is polluted, our oceans and rivers are pull of waste and our natural resources are running out. Because of our thoughtless quest for increased convenience, our country is in a state of social decay. Our thoughtlessness towards the environment is manifesting itself in our personalities and we seem to care less and less about one another every year. In our effort to decrease social decay, those classes which focus on the evolution of thinking should begin to emphasize elements of responsibility and morality towards our environment and towards fellow human being. Just as science gives us objective rules for the observation and illumination of our natural environment, morality helps us to taper those illumination with responsibility. The science teacher should include aspects of morality as a supplemental complement to his or her classes. If we know the essence and order of nature and act within established rules, any negative effects of future scientific progress will be significantly reduced.

간섬유화를 유동한 랫드에서 동충하초(冬蟲夏草)의 효소 활성에 과한 연구

김상덕,이건목,김기영,이기남 圓光大學校 醫科學硏究所 1999 圓光醫科學 Vol.15 No.1

Purpose: We study on the effects of Cordyceps sinensis (Dongchunghacho: DCHC) about activity of hepatic enzyme, which is presumed to be effective on the liver disease at Oriental Medicine. Methods: In the study, the antifibrotic effects of DCHC was investigated by oral applicalion on liver fibrosis induced in rats. Female Sprague Dawly rats were divided in 3 groups (control, liver fibrosis induced group, liver fibrosis induced and DCHC oral application group). For liver fibrosis induction, rats were i. p. injected in 11 weeks (0.125㎖/rat/day). Rats were treated for 10 weeks with DCHC extracts(0.16g/㎏/day). After application of DCHC, all group rats were sacrified. and collected blood and liver tissue. After centrifugation of blood, sera was used for the measurement of clinical biochemistry (ALT, AST, ALP, total bilirubin). The parameter of collagen deposition in liver tissue (hydroxyproline: HYP) was measured by a colorimetry. Results: In the result, jaundice was not observed in all groups, but was showed hepatomegaly in CCl4 treated group and CCl4/DCHC applicated group. The ratio of body liver weight of CCl4 treated rats was significantly higher than in DCHC treated rats (5.2±0.4%, 4.0±0.3%, p<0.01), but the weights of spleen and kidney in all group investigated were not changed significantly. The content of HYP was significantly lower in CCl4 with DCHC group than in CCl4 group (642.0±54.0, 688.0±30.5 ㎍/1g, p<0.05). In DCHC treated group, the values of AST, ALP, BUN, γ-GTP were very low compared with only CCl4 intoxificated group(p<0.01). This result represents that CCl4 injection induced liver fibrosis in 11 weeks. DCHC inhibited significantly the accumulation of collagen in the extracellular space and the activities of AST, ALT, ALP, γ-GTP in serum. Conclusion: It conclude that DCHC extracts is proven to protect against liver fibrosis in rat and to stimulate liver function.

朝鮮時代 地方 邑治의 造營規範에 관한 硏究 : 朝鮮後期 史料에 나타난 忠淸道를 중심으로 Focused on ChungChong-Do in the Literature of the Late Chosun Dynasty

김기덕 대한건축학회 2004 대한건축학회논문집 Vol.20 No.5

This study is to find out the standard in building the Eupchi in Chungchong province with Chungchong-do regional maps and Eupjis being compiled in the late Chosun dynasty. In the layout of Eupchi(the center of an administrative district in counties and prefectures) in Chungcheong-do, which was influenced by Feng-Shui, the most central core institution was not Gaeksa but Dongheon. Dongheon mostly took Jinsan of Eupchi as the center of Eupchi and government office. The building of Eupchi is on the principle that was the city where Jwamyo-Usa(the principle which placed Divine palace east of the main palace, an altar for god of soil grain west) and Jeonjo-Husi(the principle which placed government buildings south of the main palace, a market north) of Jurye-Gogonggi(an urban design manual in ancient China) that was a plan standard of the Hanyang. Sajikdan of Eupchi is the same layout as it was located in the west of Eupchi, as Sajikdan of a capital city was located in the right of a palace. And in the Usa of Eupchi, Gaeksa corresponded to Jongmyo, the location of it was related with the main road to pass by Gunhyeon. As for the Jeonjo-Husi of Eupchi, it can say that the general idea of Jeonjo in capital city applied. Jakcheong corresponding to a general idea of Jeonjo, is located in the front of Oesammun or right and left. And the Jangsi of Gunhyeon was opened in front of government office or Gaeksa, and the Gunhyeon which had Eupseong was established in the inside and outside of Eupseong. Therefore, in the Jeonjo-Husi having been a planning principle of the capital, Jeonjo was applied to Eupchi like Hanyang, but the general idea of Husi was transformed because of the topography and the road.

전기 치수 검사 시 역치 자극 이후 과용(過用) 자극 시간의 측정

남기창,안선희,김수찬,김덕원,이승종 大韓齒科保存學會 2004 Restorative Dentistry & Endodontics Vol.29 No.3

Use of electric pulp testing elicits painful response in vital teeth. In this study, we examined the excessive time from pain feeling to stimulation disconnection in clinical situation. D626D (Parkell Inc., USA.) scan type electric pulp tester was used in total of 23 young healthy individuals. Each of the right central incisors and first premolars were used as testing teeth. Stimulation disconnection was achieved by EMG in anterior belly of digastric muscle, finger span, and voice and the excessive stimulation time over the sensory threshold was recorded. As a result, we found that the short responses before the stimulation disconnection appeared following order: EMG, finger span, and voice. The EMG disconnection is suggested to be used to reduce the excessive stimulus time in electric pulp testing.

대량재해에 있어 미토콘드리아 DNA의 다형성을 이용한 개인식별

이숭덕,김기범,이윤성,최영태,신창호,이정빈 大韓法醫學會 1996 대한법의학회지 Vol.20 No.1

The mitochondrial DNA(mtDNA) is a small extranuclear DNA molecule that has been sequenced in man. the mtDNA has distinct characteristics over nuclear DNA. First, the evolutionary rate of nucleotide substitution appears to be larger compared with the nuclear DNA. Second, mtDNA is maternally inherited, so the determination of the various haplotype is unequivocal and no recombination has to be involved. Third, there is a 1.1 kb long control region, which shows severe polymorphism. These characteristics have been applied for several evolutionary study. Furthermore, they exist in cytoplasm with numerous copy number and their size, 16,569 bp is small relative to nuclear DNA, so they are more resistant to degradation or can be types in samples with only cytoplasm such as hair shaft without hair root. These presented the possibility of mtDNA as a tool in individual identification, especially when the nuclear DNA be unavailable. Actually, polymorphism in control region has been applied to individual identification for the skeletal remain found in Vietnam war. So we decided to apply the polymorphism of mtDNA in control region for the individual identification in case of mass disaster-"Downfall of Sampoong Department". Human remains from total 27 different individuals and 178 control persons were submitted for the individual identification. As the mtDNA comparison could be done through maternal lineage, 12 individual from 9 families from the control group were ruled out, because these families were consisted of father or were seeking for their father. Sequencing for the mtDNA control region was done using ABI automatic sequencer and DyeDeoxy Terminator Cycle Sequencing Kit. For convenience, sequencing reaction was done for two separate control region, region I from 16016-16401 in Anderson sequence, and regionⅡ from 048-388. First, sequences in regionⅡ of all samples and control persons were compared, and 20 samples were ruled out with no identical sequences in control group. Remaining 7 samples showed identical sequences with some of the control persons in three groups, and these identical pairs underwent mtDNA region I study. After region I study all samples except two dropped out in blood relationship. For the confirmation, STR and VNTR study such as MCT118, apoB, YNZ22, vWF, MBP, D21S11, TC-11 were done for remaining the two samples. The result denied the blood relationship between these two samples and any of the control group.

다량재해에 있어 미토콘드리아 DNA의 다형성을 이용한 개인식별 : 삼풍백화점 사건에 대하여

이숭덕,신창호,김기범,최영태,이윤성,이정빈 內務部 國立科學搜査硏究所 1996 國立 科學 搜査 硏究所 年報 Vol.28 No.-