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      • KCI등재

        산재요양기관 종사자에서 잠복결핵감염 유병율 및 위험요인

        황주환,정지영,최병순,Hwang, Joohwan,Jeong, JiYoung,Choi, Byung-soon 한국산업보건학회 2017 한국산업보건학회지 Vol.27 No.3

        Objectives: The major objective of this study was to investigate the prevalence of and risk factors for latent tuberculosis infection (LTBI) among employees at a workers' compensation hospital. Methods: Among the 394 employees at Incheon Hospital, 362 were enrolled in the study. An interferon-gamma release assay(IGRA) for diagnosis of LTBI was performed using QuantiFERON$^{(R)}$ TB Gold In-Tube(QFT-IT). Risk factors for LTBI were analyzed using logistic regression analysis. Results: The overall prevalence of LTBI was 32.0%(116/362). The non-medical departments have a significantly high prevalence compared to medical departments(39.7% vs 23.2%). In multivariate logistic regression analysis, experience working in the pneumoconiosis hospital(OR, 3.6; 95% CI, 1.3-10.3) was associated with development of LTBI. Conclusions: Korean guidelines for the management of tuberculosis recommend annual regular health examinations for TB and LTBI for health care workers(HCWs). Considering the high prevalence of and risk factors for LTBI among non-HCWs, it suggests a need for annual regular health examinations for TB and LTBI for all employees at workers' compensation hospitals, including pneumoconiosis hospitals.

      • KCI등재

        Alteration in Phenolic Compounds and Antioxidant Activities of Aronia melanocarpa Ethanol Extracts following Fermentation Using Different Strains of Leuconostoc mesenteroides to Develop Natural Antibiotic Alternative

        황주환,강주희,이기환,이재훈,이상무,김남형,김주영,김은중,Hwang, Joo Hwan,Kang, Ju Hui,Lee, Ki Hwan,Lee, Jae Hoon,Lee, Sang Moo,Kim, Nam Hyung,Kim, Joo Young,Kim, Eun Joong Korean Association of Organic Agriculture 2014 韓國有機農業學會誌 Vol.22 No.4

        Antioxidant activity is important for reducing oxidative stress that causes various metabolic disorders. Metabolic disorders are highly related to loss of productivity in livestock. Therefore, development of effective antioxidant compounds originating from plants is important for organic agriculture. Phenolic compounds in edible plants are regarded as major components relevant to antioxidant activity. The present study investigated the changes in antioxidant activity and phenolic compound profiles of Aronia (Aronia meloncarpa) by fermentation using different strains of Leuconostoc mesenteroides. A total of 5 strains of L. mesenteroides were used as starter cultures and their ${\beta}$-glucosidase activities were measured. A total of 6 experiment runs were prepared, one for control (uninoculated) and the others (inoculated) for treatments. For biological activity, antioxidant and antibacterial activities were measured. For phenolic compound profiling, TLC and HPLC analysis were performed. The strains of KACC12313 and KACC12315 showed greater enzyme activity than others. Treatment with KCCM35046 showed strong and broad antibacterial activity against to Listeria monocytogenes. Treatments with KCCM35046 and KACC12315 showed the highest total polyphenol content. The highest antioxidant activity was found in KACC12315 treatment. No remarkable alteration was found in thin layer chromatography (TLC) analysis. In phenolic compound profiling analysis, KCCM35046 showed notable alteration in compound area ratio compared to others and also showed the highest caffeic acid content. In chlorogenic acid, treatments with KCCM35046 and KACC12315 showed great content than others. Treatment with KACC12315 showed the greatest content of trans-ferulic acid. As a result of relative performance indexing analysis, L. mesenteroides KCCM35046 and KACC12315 were selected as the best strain for the fermentation of Aronia.

      • KCI등재

        논 토양에서 사일리지용 수수 × 수수 교잡종 재배시 화학비료와 발효 돈분 액비 혼용 시용이 생육특성 및 영양성분에 미치는 영향

        황주환,이상무,Hwan, Hwang Joo,Lee, Sang Moo 한국초지조사료학회 2015 한국초지조사료학회지 Vol.35 No.4

        본 실험은 논 토양에서 사일리지용 수수 ${\times}$ 수수 교잡종 재배시 화학비료와 발효 돈분 액비 혼용 시용이 생육특성 및 영양성분에 미치는 영향을 조사하고자 실시하였다. 실험설계는 화학비료 100% 처리구 (C), 화학비료 70% + 돈분액비 30% 처리구 (T1), 화학비료 50% + 돈분액비 50% 처리구 (T2), 화학비료 30% + 돈분액비 70% 처리구 (T3) 그리고 돈분액비 100% 처리구 (T4)로 한, 5처리 3반복 난괴법으로 배치하였다. 이때 돈분 액비 시용은 질소량만을 기준으로 하였다 (150 kg/ha). 초장, 엽장, 엽폭 그리고 경의 굵기는 T4구가 유의적으로 작게 나타났다 (p<0.05). 경의 경도는 돈분액비 시용 비율 낮고 화학비료 시용 비율이 높을수록 유의적으로 증가하였다 (p<0.05). 생초수량은 T2구가 높았던 반면 T3구가 낮게 나타났다 (p<0.05). 그러나 건물 수량 및 TDN 수량은 처리구들 간에 유의적인 차이를 보이지 않았다. 조단백질 함량은 T1구가 다른 구에 비하여 높게 나타났다 (p<0.05). 조지방 함량은 T1, T2, T3 그리고 T4 처리구들 간에는 유의적인 차이가 없었지만, C구와는 유의적인 차이를 보였다 (p<0.05). NDF와 조섬유 함량은 각각 T3구와 C구에서 높게 나타났다 (p<0.05). 그러나 ADF 함량은 처리구들 사이에 유의적인 차이를 보이지 않았다. 총무기물 함량은 T1 > T2 > T4 > T3 > C 구 순으로 높게 나타났다 (p<0.05). 유리당 함량은 T1과 C구가 다른 처리구에 비하여 유의적으로 높게 나타났다 (p<0.05). 이상의 결과를 종합해 볼 때, 돈분액비 시용은 화학비료에 비하여 수량성, 영양성분에 크게 떨어지지 않기 때문에 사일지용 수수 ${\times}$ 수수 교잡종 재배시 돈분액비와 화학비료를 혼용 시용 하거나 돈분액비 만 시용하여도 큰 무리가 없는 것으로 판단된다. This study was conducted to investigate the influence of the mixed application of chemical fertilizer (CF) with liquid swine manure (LSM) on the agronomic characteristics, dry matter yield, minerals, and free sugar in cultivating Sorghum ${\times}$ Sorghum Hybrid (SSH) on paddy soil. The field experiment was designed in a randomized block design with three replications and consisted of CF 100% (C), CF 70% + LSM 30% (T1), CF 50% + LSM 50% (T2), CF 30% + LSM 70% (T3), and LSM 100% treatment (T4). The application of LSM was based only on the nitrogen (150 kg/ha). Plant length, leaf length, leaf width and stem diameter were significantly the lower in T4 (p<0.05). Stem hardness increased significantly (p<0.05) as the LSM application rate decreased. Fresh yield was the highest in T2, whereas the lowest in T3 (p<0.05). However, dry matter yields and TDN yield did not show significant difference among treatments. Crude protein was the highest in T1 (p<0.05). Crude fat content did not significant differences between the T1, T2, T3 and T4, but C showed a significantly different (p<0.05). NDF and crude fiber were the highest in T3 and C, respectively (p<0.05). However, ADF did not show significant difference among treatments. Total mineral contents were higher in the order of T1> T2> T4> T3> C (p<0.05). Free sugar contents were significantly higher at T1 and C as compared to other treatments. The analysis of all the above results suggests that the application of liquid swine manure is very effective, considering the yield performance and the content of mineral and free sugar. In addition, liquid swine manure may be possible to grow SSH without chemical fertilizer.

      • KCI등재

        잠복결핵감염 양성인 분진작업 근로자에서 활동성 결핵 발병률

        황주환 ( Joo Hwan Hwang ) 한국산업보건학회 (구 한국산업위생학회) 2020 한국산업보건학회지 Vol.30 No.1

        Objectives: Previous study has shown that the positive rate of latent tuberculosis infection (LTBI) among former workers in dusty environments was higher than that among high-risk groups of tuberculosis (TB). The objective of the present study was to identify the development of active TB among former workers in dusty environments diagnosed with LTBI. Methods: Between January 2015 and May 2017, 796 former workers in dusty environments who had been subjects of epidemiology research for work-related chronic obstructive pulmonary disease (COPD) had received the QuantiFERON-TB® Gold In-Tube (QFT-GIT) from the Institute of Occupation and Environment (IOE) under the Korea Workers’ Compensation and Welfare Service (KCOMWEL). Among them, 437 participants who received a health examination for work-related pneumoconiosis between January 2015 and December 2018 were selected as study subjects. Active TB was defined as a positive result for active PTB and non-tuberculosis mycobacteria infection in the result of the Pneumoconiosis Examination Council’s assessment by KCOMWEL. Results: A total of 437 subjects were followed up for 2.1 years. Four of them (4/437, 0.9%) developed active TB during the follow-up period. The attack rate of active TB among subjects who were diagnosed LTBI positive and those who were diagnosed LTBI negative were 0.9% (3/320) and 0.9% (1/115), respectively. Conclusions: Most previous studies reported that the attack rate of the development of active TB in subjects who had been diagnosed LTBI positive was higher than that among subjects who had been diagnosed LTBI negative. To the contrary, the present study found that the rate of developing active TB among former workers in dusty environments diagnosed as LTBI positive was not higher than that in those who were diagnosed LTBI negative.

      • KCI등재

        고내구성능을 갖는 해저터널 방화문 설계방안 및 성능시험 연구

        박상헌,황주환,최영환,안승주,유용호,Park, Sang-Heon,Hwang, Ju-Hwan,Choi, Young-Hwan,An, Sung-Joo,Yoo, Yong-Ho 한국터널지하공간학회 2018 한국터널지하공간학회논문집 Vol.20 No.2

        In the tunnel of domestic high - speed railway, the main fire - fighting facility, fire - extinguishing passageway, is installed. However, due to the high pressure of the high - speed train, frequent breakage and maintenance are caused by strong shock and long - term vibration. In order to solve these problems, it is necessary to improve the fire door, but in Korea, it is installed by submitting a certificate by simple KS F 2296 performance test. At present, it is developed as a simple test certification by producing a real scale fireproof door without the theoretical examination in advance, so that a high cost for improvement is occurring in Korea. Therefore, through this study, structural analysis study which can preliminary structure review was carried out in order to design the refuge connection passage fire door and to improve the performance improvement. In order to secure the reliability of the result value, the official authentication test (KS F 2296) were compared. 국내 고속철도 터널에 주요 방재시설물인 피난연결통로 방화문이 설치되고 있으나, 고속으로 통행하는 열차의 고압력으로 인하여 방화문에 강한 충격 및 장기간 진동으로 인하여 잦은 파손 및 유지보수가 발생되고 있다. 이러한 문제를 해결하기 위해 방화문 개선이 필요하나, 국내에서는 단순 KS F 2296 성능시험에 의한 인증서를 제출하여 설치되고 있다. 현재 국내에서는 사전에 이론적인 검토 없이 실규모 방화문 제작에 의한 단순 시험인증 여부로 개발 되다보니, 개선을 위한 고비용이 발생되고 있는 실정으로 사전에 구조적인 안전을 확보할 수 있는 설계방안의 검토가 필요하다. 따라서 본 연구를 통하여 피난연결통로 방화문 설계 및 성능개선 효율화를 위해 사전 구조 검토가 가능한 구조해석 연구를 수행하였으며, 이러한 결과 값에 대한 신뢰성을 확보하기 위해 실규모 시작품 제작을 통한 공인 인증시험(KS F 2296)에서 발생된 결과 값을 비교검토 하였다.

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