http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
폐렴구균에 의한 지역사회 획득 폐렴에서 페니실린 내성률과 내성에 따른 임상경과에 관한 연구
홍지현 ( Hong Ji Hyeon ),이형석 ( Lee Hyeong Seog ),정승현 ( Jeong Seung Hyeon ),김규원 ( Kim Gyu Won ),엄광석 ( Eom Gwang Seog ),이재명 ( Lee Jae Myeong ),장승훈 ( Jang Seung Hun ),김동규 ( Kim Dong Gyu ),현인규 ( Hyeon In Gyu 대한결핵 및 호흡기학회 2003 Tuberculosis and Respiratory Diseases Vol.54 No.3
베체트 증후군 환자에서 혈관내피성장인자(Vascular Endothelial Growth Factor, VEGF)의 상승
홍지현 ( Ji Hyun Hong ),김현숙 ( Hyun Sook Kim ),김해림 ( Hae Rim Kim ),박미경 ( Mi Kyung Park ),윤종현 ( Chong Hyeon Yoon ),이상헌 ( Sang Heon Lee ),김호연 ( Ho Youn Kim ),박성환 ( Sung Hwan Park ) 대한류마티스학회 2005 대한류마티스학회지 Vol.12 No.3
Objective: Vascular endothelial growth factor (VEGF) is a potent endothelium-specific cytokine and stimulates inflammation and angiogenesis. Vascular endothelial dysfunction is one of the characteristic features of Behcet`s syndrome. We previously demonstrated the possible involvement of proinflammatory cytokines (TNF-α, IL-15, MIF) and chemokines (IL-8, MCP-1, MIP-1α) in the etiopathogenesis of Behcet`s syndrome and its association with disease activity. In this study, we assesed VEGF levels in patients with Behcet`s syndrome and its relation with disease activity. Methods: Serum VEGF levels of 65 patients with Behcet`s syndrome and 35 healthy control volunteers were measured by enzyme-linked immunosorbent assay. The level of MIF and IL-8 were also measured in 41 pateints. Among the 65 patients, 18 patients were in active state of disease which was classified according to clinical finding. Results: The mean serum VEGF levels were higher in patients of Behcet`s syndrome than control subjects (332.7 pg/mL vs. 234.4 pg/mL, p=0.004) and patients with active disease had significantly higher level of VEGF than inactive disease (377.8 pg/mL vs. 265.0 pg/mL, p<0.05). There is no difference in the mean serum level of VEGF between Behcet`s syndrome with vascular complication and without vascular complication. Serum level of VEGF showed strong positive correlation with MIF (r=0.57, p=0.001). Conclusion: Serum VEGF levels are elevated in patients with Behcet`s syndrome, particularly in active state and have positive correlation with MIF. These results suggest that the increased VEGF levels in serum of Behcet`s syndrome patients may participate, like other proinflammatory cytokines and chemokines, in the pathogenesis of Behcet`s syndrome.
혈청음성 척추관절병증 환자의 발꿈치뼈 부착부병증에 대한 초음파 검사의 유용성
김해림 ( Hae Rim Kim ),홍지현 ( Ji Hyun Hong ),윤종현 ( Chong Hyeon Yoon ),이상헌 ( Sang Heon Lee ),박성환 ( Sung Hwan Park ),김호연 ( Ho Youn Kim ) 대한류마티스학회 2005 대한류마티스학회지 Vol.12 No.2
Objective: To determine the diagnostic value of ultrasonography (US) in detection of calcaneal enthesopathies and compare US findings with clinical examination and laboratory data in patients with seronegative spondyloarthropathy (SpA). Methods: We studied fifty six patients with SpA (ankylosing spondylitis 51; psoriatic arthritis 2; reactive arthritis 3). Gray scale US and power Doppler sonography (PDS) was performed in Achilles tendons and plantar fascia using a 40 mm, 12 MHz linear probe to detect tendon thickness, loss of normal fibrillar echogenecity, blurred tendon margin, calcification, fluid collection around tendon, bony erosion, enthesopathic spur, retrocalcaneal bursitis and increased vascularity. Clinical examination including Mander enthesis index (MEI) score, erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) were examined at the same time. Results: In 112 Achilles tendons, 72.3% showed abnormal US findings, as followings, increased tendon thickness 50.9%; loss of normal fibrillar echogenecity 32.1%; blurred tendon margin 24.1%; calcification 5.4%; fluid collection around tendon 17.7%; bony erosion 16%; enthesopathic spur 8.9%; retrocalcaneal bursitis 13.4%; and increased vascularity in power Doppler sonography (PDS) 14.2%. In 112 plantar aponeurosis, 59.8% showed abnormal US withenthesopathic spur 8.9%; retrocalcaneal bursitis 13.4%; and increased vascularity in power Doppler sonography (PDS) 14.2%. In 112 plantar aponeurosis, 59.8% showed abnormal US findings, as followings, increased tendon thickness 12.5%; loss of normal fibrillar echogenecity 50%; blurred tendon margin 30.3%; bony spur 2.7%; and increased vascularity in PDS 4.5%. PDS findings well correlated with findings of gray scale US. While 46% of symptomatic patients and 41.2% of patients with tenderness have abnormal X-ray findings, 69.4% of symptomatic patients and 73.8% of patients with tenderness have abnormal US findings. Patients with clinical symptoms, elevated CRP level and >1 MEI score showed increased vascularity in PDS. Conclusion: US is a simple and useful method in the detection of enthesopathies of SpA, even in patients without clinical symptom nor abnormal radiographic finding, and PDS combined with gray scale US is more sensitive tool which reflects the clinical examination.
기관 삽관 중인 환자에서 Blind Protected Specimen Brushing의 역할
유희승 ( Yu Hui Seung ),홍지현 ( Hong Ji Hyeon ),윤장욱 ( Yun Jang Ug ),엄광석 ( Eom Gwang Seog ),이재명 ( Lee Jae Myeong ),김철홍 ( Kim Cheol Hong ),장승훈 ( Jang Seung Hun ),김동규 ( Kim Dong Gyu ),이명구 ( Lee Myeong Gu ),현인 대한결핵 및 호흡기학회 2003 Tuberculosis and Respiratory Diseases Vol.55 No.1
영상인식기반 증강현실 게임 및 Music Player의 SOC 설계
염선식 ( Seon-sik Yeom ),이우이 ( Woo-yi Lee ),지슬아 ( Seul-a Ji ),홍지현 ( Ji-hyeon Hong ),임동하 ( Dongha Lim ),박철호 ( Cheolho Park ),유윤섭 ( Yun Seop Yu ) 한국정보처리학회 2013 한국정보처리학회 학술대회논문집 Vol.20 No.2
의학의 발달로 인해 전세계적으로 인구의 고령화가 진행되어 노인 인구가 차지하는 비중이 갈수록 증가하고 있다. 본 논문은 고령자를 위한 작품으로 카메라와 FPGA Board, Touch Panel을 유기적으로 결합하여 음악감상과 운동효과를 가져올 수 있는 게임을 포함한 하드웨어기반 시스템을 소개한다. 간단히 공을 화면에 맞추는 게임과 손 모양 인식에 따라 음악을 제어할 수 있는 부분의 설계와 알고리즘을 기술하고 있다. 본 시스템은 노인들에게 편리하고 간단한 UI를 제공하여 실내에서 여가 시간을 보낼 때 부담이 가지 않는 운동을 할 수 있는 게임을 하며 음악을 들으면서 건강증진, 치매예방 및 심신을 안정시킬 수 있다. 본 시스템은 평균 77% 이상 동작인식성공률을 가진다.
노재희 ( Jae-hee Roh ),백지윤 ( Jee-yoon Baek ),홍지현 ( Ji-hyeon Hong ),이영섭 ( Young-seop Lee ) 한국정보처리학회 2019 한국정보처리학회 학술대회논문집 Vol.26 No.2
4차 산업 혁명에 따라 최근 스마트홈 연구가 활발히 이루어지고 있으며 기술이 발전함에 따라 스마트홈의 개념은 변해왔다. ‘음성’ 인터페이스를 기반으로 Google에서 제공하는 지능형 가상 비서인 Google Assistant API[1]를 이용하여 AI를 기반으로 한 음성인식 제어 수전을 제안한다. 나아가 OECD가 발표한 ‘심각한 물 스트레스 국가’에 속하는 대한민국 국민들에게 물 사용량의 실태를 확인하고 과다한 물 사용량에 대한 경각심을 일깨워준다.
경구 Cyclophosphamide로 치료했던 루푸스 환자에서 발생한 방광암
김기조 ( Ki Jo Kim ),김우태 ( Woo Tae Kim ),김성용 ( Sung Yong Kim ),홍지현 ( Ji Hyun Hong ),김해림 ( Hae Rim Kim ),윤종현 ( Chong Hyeon Yoon ),이상헌 ( Sang Heon Lee ),박성환 ( Sung Hwan Park ),김호연 ( Ho Youn Kim ) 대한류마티스학회 2004 대한류마티스학회지 Vol.11 No.3
Cyclophosphamide, a cytotoxic alkylating agent, is widely used in various benign diseases like systemic lupus erythematosus (SLE), Wegener`s granulomatosis, rheumatoid arthritis, nephrotic syndrome as well as in malignancies and organ transplantation. Cyclophosphamide is metabolized in the liver to various chlormethine metabolites and acrolein, which mediates the toxic effect to the urothelium and can cause hemorrhagic cystitis, bladder fibrosis, and has also been associated with urothelial malignancies including bladder cancer. It is known that SLE is not associated with an increased risk for the development of most of the solid tumors. But it has been suggested that the risk of the bladder cancer increases in patients with benign diseases such as SLE treated by cyclophosphamide. There are only very few reports of cyclophosphamide-induced bladder cancer in SLE so far. We report a case of a patient who developed bladder cancer 13 years after cyclophosphamide was given as therapy for SLE. This case shows that careful observation and urologic evaluation is undoubtedly important for patients treated with cyclophosphamide.
경금속에 대한 노출력이 없는 거대세포 간질성 폐렴(Giant Cell Interstitial Pneumonia)
강민종 ( Kang Min Jong ),김동규 ( Kim Dong Gyu ),정기석 ( Jeong Gi Seog ),장기택 ( Jang Gi Taeg ),박혜림 ( Park Hye Lim ),이인재 ( Lee In Jae ),홍지현 ( Hong Ji Hyeon ),이재명 ( Lee Jae Myeong ) 대한결핵 및 호흡기학회 2002 Tuberculosis and Respiratory Diseases Vol.52 No.4
한국산 벼 품종 판별에 있어서 세가지 PCR 방법들간의 효용성 비교
이강수,송문태,정오영,홍지현 한국유전학회 1999 Genes & Genomics Vol.21 No.3
The effectiveness of three kinds of PCR primers, random, microsatellite, and sequence tagged site (STS) for the fingerprinting of genetically similar Korean rice cultivars, was estimated by comparing the resolution powers of these primers to classify a set of 40 Korean rice cultivars. Among the three kinds of primers examined, the random primer showed higher resolution than the other two primer kinds to make the classification of Korean rice cultivars in condition that the agarose gels were used for separation of the bands. The dendrogram constructed from pooled data from three different PCR-methods gave a clear distinctions not only between the two cultivar groups, japonica rice and indica/japonica hybrid rice groups but also between individual cultivars within a cultivar group. The near grouping of genetically similar rice groups having similar breeding backgrounds suggests that PCR techniques can offer a reliable and effective means of assessing not only genetic variation in diverse rice germplasm but also cultivar identification between very close cultivars.