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문현종 ( Mun Hyeon Jong ),장기택 ( Jang Gi Taeg ),허진석 ( Heo Jin Seog ),최성호 ( Choe Seong Ho ),조재원 ( Jo Jae Won ),김용일 ( Kim Yong Il ) 대한소화기학회 2003 대한소화기학회지 Vol.42 No.2
Background/Aims: Ductal adenocarcinoma of the head of the pancreas can only be cured with pancreaticoduodenectomy. However, the prognosis after resection has been poor. This study analyzed the possible prognostic factors of resected ductal adenocarcinoma through pancreaticoduodenectomy in a single institution. Methods: Between Oct. 1994 and May. 2002, 81 patients underwent pancreatoduodenectomy for ductal adenocarcinoma of the head of the pancreas. Perioperative and pathologic factors were analyzed with univariate and multivariate analysis. Results: The overall 5-year survival rate of the 81 patients was 10.8% with median survival of 11.8 months. Ninety-six percent of the patients were in stage IIa, IIb or III. In univariate analysis, factors favoring survival were as follows: CA19-9 antigen≤200 U/mL (p=0.0055), no preoperative biliary drainage (p=0.018), operation time≤6.5 hr (p=0.009), RO (curative) resection (p=0.0001), negative gross vascular invasion (p=0.0012), tumor size≤3 cm (p=0.002), T lesion≤T3 (p=0.0014), no tumor necrosis (p=0.0041), no duodenal invasion (p=0.0004) and postoperative chemoradiation therapy (p=0.0365). In multivariate analysis, RO resection (p<0.001), T lesion≤T3 (p=0.03) and no duodenal invasion (p=0.001) were independent predictors of prognosis. In 20 patients, who had T lesion≤T3 without duodenal invasion and RO resection, the 5-year survival rate was 67.8%. Conclusions: After pancreaticoduodenectomy for ductal adenocarcinoma of the head of the pancreas, a favorable 5-year survival rate can be achieved in the group of patients who have T lesion≤T3 without duodenal invasion and R0 resection. (Korean J Gastroenterol 2003;42:156-163)
경금속에 대한 노출력이 없는 거대세포 간질성 폐렴(Giant Cell Interstitial Pneumonia)
강민종 ( Kang Min Jong ),김동규 ( Kim Dong Gyu ),정기석 ( Jeong Gi Seog ),장기택 ( Jang Gi Taeg ),박혜림 ( Park Hye Lim ),이인재 ( Lee In Jae ),홍지현 ( Hong Ji Hyeon ),이재명 ( Lee Jae Myeong ) 대한결핵 및 호흡기학회 2002 Tuberculosis and Respiratory Diseases Vol.52 No.4