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        Deflazacort로 성공적으로 치료한 결절성 다발성 동맥염

        최종형 ( Jong Hyoung Choi ),김대훈 ( Dae Hoon Kim ),박성훈 ( Sung Hoon Park ),신운건 ( Woon Geon Shin ),이준호 ( Jun Ho Lee ),강인수 ( In Soo Kang ) 대한류마티스학회 1999 대한류마티스학회지 Vol.6 No.3

        Polyarteritis nodosa(PAN), a systemic vasculitis involving multiple organs including the nervous system, requires a long-term glucocorticoid therapy. Deflazacort is a synthetic glucocorticoid, which has been claimed to have less side effects, but its use for vasculitis has never been reported in the literature. We report a case of polyarteritis nodosa presenting with mononeuritis multiplex causing a left foot drop, which was successfully treated with deflazacort.

      • SCOPUSKCI등재

        Helicobacter pylori 감염이 소화성 궤양 출혈에 미치는 영향

        유재영,이준호,이자영,김성균,박충기,김학양,김용범,서지영,김재삼,장명국,노병연,최종형,김종혁 대한소화기학회 1998 대한소화기학회지 Vol.31 No.4

        Background/Aims: The aim of the present study was to determine whether Helicobacter pylori infections are related to the risk of bleeding complications of peptic ulcer disease. Methods: We have examined 267 patients with symptoms and endoscopic stigmata of recent ulcer bleeding. The severity of ulcer bleeding was categorized by Forrest classification and H. pylori infection was evaluated by CLOtest. The H. pylori infection rates of the patients group were cornpared with those having uncomplicated peptic ulcer. Results: The positive rate of H. pylori infection in total patients with bleeding ulcer was 65.2% (174 of 267), which was significantly lower than that of patients with non-bleeding ulcer 72.6% (748 of 1031)(p$lt;0.05, OR;0.708, 95%, CI;0.532-0.943). However, in subgroup analysis, the positive rates of CLOtest in patients with bleeding gastric ulcer (GU) and duodenal ulcer (DU) were 59.0% (98/166) and 76.1% (70/92), respectively. These data are similar to the rates obtained from those with uncomplicated ulcers, 66.1% (302/457) in GU, and 79.3% (367/463) in DU, respectively (p=0.105, p=0.496). In the subgroups of Forrest Ia and Ib, 20 out of 21 patients (95.2%) were infected by H. pylori, and their infection rate was significantly higher than that of total patients (p$lt;0.05). Conclusions: Our results suggested that H. pylori infection was not a risk factor of bleeding complications of peptic ulcer. However, the subgroup of active ulcer bleeding, Forrest Ia and Ib could be associated with H. pylori infection.

      • SCOPUSKCI등재

        비장 농양으로 발현된 췌장 미부암

        강인수,김성균,김대경,김학양,유재영,박충기,김종혁,이종민,김용범,윤대성,최종형 대한소화기학회 1998 대한소화기학회지 Vol.31 No.6

        The splenic involveent by pancreatitis is an uncommon entity, including intrasplenic pseudocyst, abscess, hemorrhage, infarction, splenic rupture, and vascular injury. Splenic abscess may be caused by inflammation of pancreas. Panceatic cancer is a rare cause of acute pancreatitis and an extremely rare cause of pancreatic abscess. Several diseases developed in the splenic hilum and pancreatic tail, require differential diagnosis. particularly, it is difficult to diagnose a pancreatic tail cancer without specific symptom or sign. We have examined a sixty four-year-old woman complaining of left upper quadrant pain, and reported that it is a case of intrasplenic abscess assosiated with acute pancreatitis and pancreatic tail cancer. The case was confirmed by resected specimen. On operative findings, the peripancreatic fatty tissue had severe adhesions to the pancreatic tail and splenic hilum, where the abscess had formed. By microscopic examination, hemorrhagic neciasis and inflammatory change were observed in the spleen specimen. The pancreatic tail specimen had a 2×2 cm sized mass and was proven to be a well-differentiated adenocarcinoma with hee resection margin.

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