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Helicobacter pylori 감염이 있는 환자의 배우자에서의 감염빈도와 임상적 의의
김학양,유재영,박충기,김종혁,김용범,장웅기,김재삼,박수종 대한소화기학회 1998 대한소화기학회지 Vol.31 No.6
Background/Aims; The transmission mode of Helicobaeter pylori infection has not been definded. We investigated the seroprevalence of H. pylori infection in spouses of infected patients to clarify the transmission mode of H. pylori infection, Methods: Sera were collected from 26 spouses of infected patients and examined for H. pylori infection by serology. We compared the antibody responses to H. pylori proteins (CagA, VacA and urease subunits) in 5 couples. Results: H. pylori infection was observed in 20 out of 26 spouses (77%). The infection rate was increased from 50% in less than 10 years of cohabitation to 100% in more than 31 years of cohabitation. The gastroscopic exarnination for the infected patients revealed chronic gastritis in 6, gastric ulcer in 9, duodenal ulcer in 8, concurrent gastric and duodenal ulcer in 2, and gastric cancer in 1. In spouses, the gastroscopy showed chronic gastritis in 10 and pyloric canal ulcer with H. pylori infection in 1. The couple with pyloric canal ulcer showed similar antibody responses to CagA, VacA and urease subunits. Conclusions: This study suggested that H. pylori might be transmitted via oral to oral route. Further study about the risk of gastroduodenal lesion in spouses is needed.
김학양,유재영,박충기,김종혁,김용범,곽상택 대한소화기내시경학회 1999 Clinical Endoscopy Vol.19 No.4
Most intussusceptions occur in children under 1 year of age whereas 5%∼10% occurs in adults. Although intussusception has an acute occurrence in children, symptoms in adults may be subacute or chronic, and the diagnosis is often delayed. In contrast to adults, intussusception in children is the most common cause of intestinal obstruction, and one of the most frequent causes of surgical emergencies. While idiopathic cases account for more than 90% of those seen in children, many cases in adults are generally related to neoplasm. However, intussusception due to a primary malignant lymphoma of the small intestine is a rare clinical condition. There is little information on the role of colonoscopy in colonic intussusception. Two cases are herein reported, of malignant lymphoma in the ileocecal region causing intussusceptions in which the diagnosis and reduction of intussusception were made by colonoscopy. Colonoscopy plays a useful role in the diagnosis and management of intussusception. The clinical, radiographc, endoscopic, and pathologic findings are described with brief reviews of related literature.