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최병철,강효숙,곽현수,손의동,Choi, Byung-Chul,Kang, Hyo-Sook,Kwak, Hyun-Soo,Sohn, Uy-Dong 대한약학회 2009 약학회지 Vol.53 No.2
The purpose of this study is to investigate the best way that health functional food contributes the diversification of pharmacy management at the new point after the separation of prescribing and dispensing practice. In the question of the number of prescription paper, it was more than 200 papers (18.9%), next 100 papers (11.3%). In case of daily total sales volume except prescription fee, it was more than 1,000,000won (28.3%). About the motivation using health functional food, the reason for activation of pharmacy management was 66%. The selling method was mainly by pharmacist recommendation and consumer's need. In comparison with after and before the separation of prescribing and dispensing, more than 60% of subjects answered that sales volume was decreased and no changed. Concerning the ratio of total sales volume to health functional food within 5 years, 66% of subjects expected that it will be increased positively. The type of best pharmacy to handle health functional food was community pharmacy. These results suggest that the handling of health functional food by pharmacist will greatly increase in near futures and will be very important portion for pharmacy management.
촉매연소기용 귀금속 촉매와 조촉매의 열적 내구특성 연구
최병철,고병운,김명환,신혁,Choi, Byungchul,Ko, Byeongwoon,Kim, Myeonghwan,Sin, Hyeok 한국교통대학교 융복합기술연구소 2020 융ㆍ복합기술연구소 논문집 Vol.10 No.1
The purpose of the study is to investigate the thermal durability characteristics of the Pt catalyst and additives used in a catalytic combustor. The catalyst used in the experiment was based on Pt (3 wt%), and a total of 12 types were prepared using a combination of additives (Ni, La, Ce, Fe, and Co). From the results, In the fresh state, the two types of combination catalysts with the highest C<sub>3</sub>H<sub>8</sub> conversion were Pt_Ce (79.9%) at 500℃, and in the three types of combination catalysts, Pt_La_Ni (93.4%) at 500℃ had the best performance. Among aged catalysts at 850℃ and 8 hours, Pt-La-Ni and Pt-Ni-Ce catalysts showed the highest C<sub>3</sub>H<sub>8</sub> conversion of about 71% at 500℃.
한 블록 당 실험의 크기가 2인 경우 정의대비를 이용한 2<sup>n</sup>요인실험과 그 일부실시법의 설계방법
최병철,Choi, Byoung-Chul 한국통계학회 2008 Communications for statistical applications and me Vol.15 No.4
동일 환경에서 할 수 있는 실험의 크기가 2인 경우 $2^n$요인실험과 그 일부실시법을 설계하려면 교락법을 반복적으로 사용해야한다. $2^n$요인실험 또는 그 일부실시법의 교락법들을 적절히 조합하면 모든 주효과와 2인자 교호작용효과 전부 또는 일부를 검출할 수 있는 실험을 설계할 수 있다. 이런 실험을 설계하기 위해 정의대비를 이용했고 설계된 실험의 처리조합을 제시하였다. Confounding techniques have to be used repeatedly in the situations where it is necessary to perform only 2 runs under homogeneous conditions in $2^m$ factorial and fractional factorial experiment. Combinations of confounded $2^m$ factorial and fractional factorial designs enable the estimation of all main effects and all of or a part of 2 factor interaction effects. Defining contrast are used for our designs and treatment combinations of designs to be run are presented.
최병철,유환국,안욱수,허용,김병열,이정호,유회성,Choi, B.C.,Yoo, H.K.,Ahn, W.S.,Hur, Y.,Kim, B.Y.,Yoo, H.S. 대한심장혈관흉부외과학회 1991 Journal of Chest Surgery (J Chest Surg) Vol.24 No.7
To evaluate risks, complications and mortality of reoperations on heart valve prosthesis, we reviewed clinical records of 53 patients who underwent reoperation because of prosthetic valve failure[PVF], from Jan 1959 through Jun. 1991. They had undergone 48 mitral, 10 aortic valve rereplacement Primary tissue failure was the main cause of reoperation : it occurred in 51 valves at a mean postoperative interval of 58 months. Calcification and collagen disruption of prosthesis were main causes of primary tissue failure in macro and micropathology, In 3 failing mechanical prostheses, paravalvular leak was in 2 cases, another one case had the thrombi at the hinge portion. If conditions such as emergency operation with or without endocarditis, thromboembolism and advanced NYHA functional class are prevented, we think that reoperative valve replacement has similar morbidity and mortality to initial valve replacement surgery. But our sturdy represents higher mortality [22.6%] because of late surgical intervention failing the prevention of conditions leading to myocardial damage. In conclusion if the tearing, calcification, and a new murmur were detected the early reoperation should be considered to increase late survival.
향사양위탕(香砂養胃湯) 전탕액이 노화주의 비장, 췌장, 위장 세포의 항산화능에 미치는 영향
최병철,안택원,Choi, Byoung-Chol,Ahn, Taek-Won 사상체질의학회 2008 사상체질의학회지 Vol.20 No.2
1. Objectives The purpose of this study was to observe the anti-oxidant effects of Hyangsayangyi-tang(HY) in SD rats. 2. Methods This experiment was used the tissue of stomach, spleen and pancreas cells of 6, 52 and 68 weeks old SD rats. Each age group was again divided into three groups. One group, as normal group, was not-treated cells, another group, as control group, was saline-treated cells, and the last group, as experimental group, was HY-treated cells. After culture for 48 hours, each groups measured the level of SOD, GSH, MDA and NO in the tissue of stomach, spleen and pancreas cells. 3. Results and Conclusions The activity of SOD were significantly increased in spleen cell of 52, 68 w-HY group, pancreas cell of 68 w-HY group and in stomach cell of 52, 68 w-HY group compared with those of the normal and the control groups. The level of GSH were significantly increased in spleen cell of 52, 68w-HY group and in pancreas cell of 68w-HY group compared with those of the normal and the control groups. The level of MDA were significantly decreased in pancreas cell of 68 w-HY group compared with those of the normal and the control groups. The level of NO were significantly decreased in spleen cell of 68 w-HY group, pancreas cell of 52, 68w-HGD groups compared with those of the control groups. According to results, HY showed anti-oxidant effect. Investigation into the clinical use of the HY is suggested for future research.
최병철,한승완,정병호,김정녀,Choi, B.C.,Han, S.W.,Chung, B.H.,Kim, J.N. 한국전자통신연구원 2007 전자통신동향분석 Vol.22 No.1
국내외적으로 지능형 차량 및 텔레매틱스/ITS 연구 개발을 통해서 차량에 IT 기술 접목을 위한 노력을 가속화하고 있다. 우리나라의 경우 산업자원부가 미래 10대 전략품목으로 자동차 부분에서 지능형 차량을 선정하였으며, 정보통신부는 u-IT839의 핵심서비스로 텔레매틱스/ITS 서비스를 추진하고 있다. EU는 i2010 Flagship에서 intelligentcar initiative 프로젝트를 통해 지능형 차량 및 보안을 위한 전략 수립과 세부과제를 수행하고 있다. 또한, IEEE 802.11p/P1609(WAVE)와 ISO TC204/WG16CALM에서는 차량 통신 보안 및 서비스에 대해서 고려하고 있다. 현재 지능형 차량과 관련하여서는 다양한 사업 모델이 제시되고 있으며, 자동차 업계의 BM과 이동통신 업계의 AM이 동반 성장하고 있다. 본 기고문은 지능형 차량 및 텔레매틱스/ITS와 관련한 보안 기술 동향을 살펴본다.
스퍼터링 타겟용 저온 분사 Cu-15 at.%Ga 코팅 소재의 특성에 미치는 열처리 분위기의 영향
최병철,박동용,김형준,오익현,이기안,Choi, Byung-Chul,Park, Dong-Yong,Kim, Hyung-Jun,Oh, Ik-Hyun,Lee, Kee-Ahn 한국분말야금학회 2011 한국분말재료학회지 (KPMI) Vol.18 No.6
This study attempted to manufacture a Cu-15 at.%Ga coating layer via the cold spray process and investigated the effect of heat treatment environment on the properties of cold sprayed coating material. Three kinds of heat treatment environments, $5%H_2$+argon, pure argon, and vacuum were used in this study. Annealing treatments were conducted at $200{\sim}800^{\circ}C$/1 hr. With the cold sprayed coating layer, pure ${\alpha}$-Cu and small amounts of $Ga_2O_3$ were detected in the XRD, EDS, EPMA analyses. Porosity significantly decreased and hardness also decreased with increasing annealing temperature. The inhomogeneous dendritic microstructure of cold sprayed coating material changed to the homogeneous and dense one (microstructural evolution) with annealing heat treatment. Oxides near the interface of particles could be reduced by heat treatment especially in vacuum and argon environments. Vacuum environment during heat treatment was suggested to be most effective one to improve the densification and purification properties of cold sprayed Cu-15 at.%Ga coating material.
Raw 264.7 세포에서 유해산소 생성에 미치는 Caffeic Acid의 영향
최병철,Choi, Byung-Chul 대한약학회 2008 약학회지 Vol.52 No.6
To investigate effect of caffeic acid on the intracellular reactive oxygen species production, we used DHE for intracellular superoxide anion production, DCF for intracellular ${H_2}{O_2}$ production and DHR for intracellular hydroperoxide production in Raw 264.7 cells. DPPH assay showed that antioxidant activity of caffeic acid with 39.5 ${\mu}M$ of ${IC}_{50}$ values was similar to that of ascorbic acid with 41.3 ${\mu}M$ of ${IC}_{50}$ values. Caffeic acid dose-dependently inhibited silica-induced ${H_2}{O_2}$ and hydroperoxide production but did not affect superoxide anion production in Raw 264.7 cells, which suggest that antioxidant effect of caffeic acid acts on the post-step of superoxide anion. On the other hand, caffeic acid showed a potent antioxidant effect in $lCuSO_4$-induced lipid peroxidation. Furthermore, plasma superoxide dismutase activity (3.43${\pm}$0.23 U/ml) in 10 mg/kg caffeic acid-fed mice was significantly higher than that (2.32${\pm}$0.24 U/ml) of control. From the above results, it is referred that caffeic acid appears to have potent anti-oxidant activity in both cell system and in vivo system.