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최명범,우향옥,김점수,서지현,임재영,박찬후,유진종*,윤희상 대한소아청소년과학회 2004 Clinical and Experimental Pediatrics (CEP) Vol.47 No.4
Purpose:The purpose of this study was to investigate the diagnostic value of spiral computed tomography (CT) using contiguous slices with partially thin sections around the hilar level in the bronchial foreign bodies of children with a vague history of aspiration. Methods:Fourteen children were identified to be examined with spiral CT due to obscure histories of aspiration episodes. A retrospective analysis of the medical records provided information concerning the clinical and radiological findings. Results:Of the 14 patients examined with spiral CT, there were no significant differences among the clinical and initial radiological findings with the exception of gender distribution. However, the spiral CT scans allowed accurate discrimination among patients with a vague history of aspiration episodes, in which seven were identified with bronchial foreign body aspiration and seven with bronchiolitis, asthma, tracheobronchitis and/or pneumonia. Conclusion:We found that spiral CT using contiguous slices with partially thin sections around the hilar level are a useful non-invasive method in the early diagnosis of bronchial foreign bodies in children with a vague history of aspiration. 흡입 병력이 애매한 소아에서폐 CT의 유용성경상대학교 의과대학 소아과학교실, 진단방사선과교실*최명범·우향옥·김점수·서지현·임재영박찬후·유진종*·윤희상목 적 : 소아 응급 질환인 기관지 내 이물 흡인의 진단을 위해서는 정확한 병력과 이학적 소견이 중요하다. 그러나 불확실한 병력과 이학적 소견을 보이는 경우에는 다양한 방사선과적 검사들이 이용된다. 이에 저자들은 기관지 내 이물 흡인의 진단에 흉부 전산화 단층 촬영(CT) 기법의 유용성을 알아보았다. 방 법 : 경상대학교병원에서 1993년 3월부터 1998년 3월까지 불명확한 기왕력을 가지면서 기관지 내 이물 흡인이 의심되었던 14명의 환아를 대상으로 임상 양상, 방사선 소견과 CT 소견을 병록 고찰을 통해 후향적으로 조사하였다. 결 과 : 대상 환아의 평균 연령은 3.14(±2.78)세로 1세에서 3세 사이 연령에 10례(71%)가 해당되었고 성별분포는 남아가 9례, 여아가 5례였다. 기침, 천명, 호흡곤란 등의 임상 증상이 시작된 날부터 내원일까지의 평균 기간은 8.57(±15.63)일이었으며, 이들은 불확실한 병력과 임상 양상, 이학적 소견을 가지며 단순 흉부촬영과 X선 투시 검사 등의 방사선학적 검사에서도 비특이적 소견을 보였으나, CT 소견으로 기관지 내 이물 흡인 7례와 세기관지염과 폐렴 7례로 감별 진단되어 의미있는 결과를 보였다.
최명범,강기수,박찬후,우향옥,이정희,이재익,백원영,윤희상,Choi, Myoung-Bum,Kang, Ki Su,Park, Chan-Hoo,Woo, Hyang-Ok,Lee, Jeong-Hee,Lee, Jae-Ik,Paik, Won Young,Youn, Hee-Shang 대한소아청소년과학회 2002 Clinical and Experimental Pediatrics (CEP) Vol.45 No.6
저자들은 폐형성부전과 다발성 선천성 기형을 가지고 있는 생존 출생아에서 말초혈액의 염색체 검사 및 FISH로 확인된 trisomy 22 1례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. We report a case of trisomy 22 in a liveborn male infant which was confirmed by fluorescence in situ hybridization(FISH), macrocultures and GTG-banding, and RHA-banding procedures of peripheral white blood cells. The infant showed lung hypoplasia, which is a unique presentation, with other clinical manifestations of previously reported cases of trisomy 22, such as intrauterine growth retardation, cleft palate, micrognathia, large atrial septal defect, limb anomalies, imperforate anus, and hypospadias. Our report gives weight to the previously reported observation that pulmonary hypoplasia may be associated in trisomy 22.
朴鏡文,崔明範 慶星大學校 1994 論文集 Vol.15 No.3
Asia NICs as Korea, Taiwan, Singapore, Hongkong has been cutthroat competition in World market with stand for an export-centered economic policy laying stress on competitive power of labor because which is poor in natural resources. Industrial Relations in NICs has come to a most important new turning point in its history because it is political democratization trend and a rise in right desires of the workers and a change in labor markets. This paper from this point of view come up with effective directions of indutrial relations in Korea as compared with the characters of the trade union organization and industrial disputes of NICs. As a result of the study, It is as follows. 1. Though recent industrial relations of every NICs relatively continues steady but Taiwan is unsettled as an activation of a labor movement with lifting of the martial law in 1987. 2. The trade union organization was a form of industrial union federation of mainly composed of enterprise union and the union organization rate showed a rapid increase in Taiwan on the other hand Korea and Singapore showed a steady decrease. 3. Analysis result from individual indexes and integration index of industrial disputes showed that it was reduced distinctly in every NICs but Korea was weaken labor competition because it was of the high absolute value as compared with the other NICs. 4. The government for the sake of labor competion's rising in Korea must enforce a fair labor policies from the standpoint of the promoting of mautonomous industrial relations. 5. Capital and labor have to conduct the pursuit of coexistence and coprosperity with a partnership spirit.
Helicobacter pylori에 의한 만성위염의 항균요법 후 위십이지장점막의 병리조직학적 변화
최명범(Myoung Bum Choi),김윤옥(Yoon Ok Kim),조윤경(Yoon Kyung Cho),신선경(Sun Kyeong Sin),김송자(Song Ja Kim),우향옥(Hyang Ok Woo),김미령(Mi Ryeung Kim),김승환(Seung Hwan Kim),윤희상(Hee Shang Youn),고경혁(Gyung Hyuck Ko),박철근(Cheo 대한소화기학회 1997 대한소화기학회지 Vol.29 No.1
N/A Background; We examined the histopathological changes of the gastroduodenal mucosa after chemotherapy against Helicobacter pylori to evaluate what happened to them, because most of patients with chronic gastritis who received the triple chemotberapy felt improvement of upper gastrointestinal symptoms in spite of its 45% clearance rate of Helicobacter pylori in our previous study. Methods; Gastric and duodenal mucosal biopsy specimens were obtained before and 2-4 weeks after the triple chemotherapy. Helicobacter pylori colonization was evaluated with urease test and histopatho]ogical examinations including hematoxy]in-eosin and Warthin-Starry silver staining. Histopathological grading of gastric and duodenal mucosa was done according to the Sydney Syste and Whitehead's criteria, respectively. Resu)ts; Decreasing pathological grades of Helicobacrer pylori density, gastric neutrophil infiltration and chronic inflammatory cell infiltration was observed in 100%, 100% and 57.6% of 26 Helicobacter pylori-cleared patients after chemotherapy, respectively. And we a]so observed the decreasing pathological grades of Helicobacter pylori density, gastric neutrophil infiltration and chronic inflammatory cell infiltration in 70.8%, 63.6% and 29.4% of 34 Helicobacter pylori-persisted patients after chemotherapy, respectively. The histopathological changes of neutrophil and chronic inflamrnatory cell infiltration after chemotherapy were correlated with the histopathological changes of Helicobacter pylori density. Chronic inflammatory cell infiltration of duodenal mucosa was decreased only in 8.6% of patients after chemotherapy. Conclusions; After chemotherapy, the histopathological grades of Helicobacter pylori density, neutrophil infiltration and chronic inflammatory cell infiltration of gastric mucosa were decreased in both Helicobacter pylori-cleared and persisted groups. (Korean J Gastroenterol 1997;29:41 - 52)
양정수,이민혜,최명범,박찬후,우향옥,윤희상,Yang, Jeong-Soo,Lee, Min-Hae,Choi, Myoung-Bum,Park, Chan-Hoo,Woo, Hyang-Ok,Youn, Hee-Shang 대한소아소화기영양학회 2002 Pediatric gastroenterology, hepatology & nutrition Vol.5 No.1
Primary peritonitis usually refers to a bacterial infection of the peritoneal cavity without a demonstrable intra-abdominal source. Most cases occur in children with ascites resulting from nephrotic syndrome or cirrhosis. Rarely, it may occur in previously healthy children less than 7years of age, usually a girl. Distinguishing primary peritonitis from appendicitis may be impossible in patients without a history of nephrotic syndrome or cirrhosis. Accordingly, the diagnosis of primary peritonitis is made only at laparotomy. We report one case of primary pneumococcal peritonitis in a 27-month-old female who underwent explorative laparotomy to discover the cause of suspicious intestinal perforation and mechanical ileus. Later, pneumococci were cultured in blood and gram-positive diplococci were isolated from the pus of peritoneal cavity.
고혈압과 뇌혈관염이 동반된 상태에서 뇌증을 보인 Henoch-Schonlein Purpura Nephritis 1례
최희라,김어진,최명범,임재영,박찬후,우향옥,윤희상,Choi, Hee Ra,Kim, Eo Jin,Choi, Myoung Bum,Lim, Jae Young,Park, Chan Hoo,Woo, Hyang Ok,Youn, Hee Sang 대한소아청소년과학회 2003 Clinical and Experimental Pediatrics (CEP) Vol.46 No.10
저자들은 9세 남아에서 고혈압과 뇌혈관염이 동반된 상태에서 뇌증을 보인 HSP 신염 1례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. Henoch-Shonlein purpura(HSP) is a systemic small-vessel vasculitis that primarily affects the skin, gastrointestinal tract, joints, and kidneys. The nervous system may be involved, less commonly than other organs. When the central nervous system(CNS) was involved, headache, changes in mental status, seizures, and focal neurologic deficits have been reported. Hypertension, uremic encephalopathy, metabolic abnomalities, electrolyte abnormalities, or cerebral vasculitis were suggested as possible causes of the neurologic manifestation. Diagnosis of vasculitic involvement of CNS is difficult. Magnetic resonance imaging of the brain is the modality of choice for the evaluation of the CNS disease. Steroid or plasmapheresis are used in treatment of cerebral vasculitis. We experienced a case of 9-year-old boy who had presented with Henoch-Schonlein purpura nephritis complicating encephalopathy accompanied by hypertension and cerebral vasculitis. Brain MRI showed multiple small nodular-linear pattern enhancing lesions in whole cerebral hemispheres and focal increased T2 signal in the right basal ganglia. We used intravenous immunoglobulin in treatment of cerebral vasculitis. We report this case with a brief review of related literature.
적혈구 이형성증(Dyserythropoiesis)의 소견을 보이는 부분 21-monosomy 증후군
임재영,서지현,최명범,박찬후,우향옥,윤희상,Lim, Jae-Young,Seo, Ji-Hyoun,Choi, Myoung-Bum,Park, Chan-Hoo,Woo, Hyang-Ok,Youn, Hee-Shang 대한소아청소년과학회 2003 Clinical and Experimental Pediatrics (CEP) Vol.46 No.4
저자들은 특이한 얼굴, 근 긴장도 증가, 정신 지체와 혈액학적으로 일시적인 적혈구 이형성증(dyserythropoiesis)의 소견을 동반한 MDS 의증의 소견과 혈소판 감소증, 호산구 증가증을 동반하는 부분 21-monosomy 증후군 1례를 신생아기부터 8세까지 추적 관찰하고 보고한다. 이와 같은 예는 우리나라에서 보고되는 첫 증례라고 사료되어 간단한 문헌 고찰과 함께 보고하는 바이다. All complete monosomy 21 appear to be lethal early in their development in humans and only survive in mosaic forms. Complete monosomy 21 is a very rare and usually debilitating genetic disorder. Partial monosomy 21 is also rare and is thought to constitute a clinical syndrome consisting of peculiar faces, hypertonia, psychomotor retardation, and slow growth. We experienced a case of monosomy 21 mosaicism. Chromosome analysis demonstrated mosaicism for cell lines in the lymphocytes examined; 45, XX, -21/46, XX. The main clinical features were craniofacial dysmorphism including high arched palate, submucosal cleft, micrognathia and arthrogryposis-like symptoms including flexion deformity of fingers. And hematological findings were revealed dyserythropoiesis, thrombocytopenia and eosinophilia. Currently, the patient has nearly compatible growth, but a mild degree of mental retardation. We report here an 8 years old female child with apparent monosomy 21 mosaicism associated with dyserythropoiesis, thrombocytopenia and eosinophilia, with a review of the associated literatures.