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백서에서 Dimethylnitrosamine에 의한 간경화의 유도와 간세포성장인자, 수용체인 c-Met, 그리고 형질전환인자-베타 1의 발현에 관한 연구
김욱환(Wook-Hwan Kim),이재호(Jae-Ho Lee),진윤미(Yoon-Mi Jin),조혜성(Hyeseong Cho),박혜리(Hye Lee Park),정민권(Min-Kwon Jung),곽연식(Yun-Sik Kwak),한상욱(Sang-Uk Han),왕희정(Hee-Jung Wang),이건욱(Kuhn-Uk Lee),김명욱(Myung-Wook Kim) 대한외과학회 1998 Annals of Surgical Treatment and Research Vol.55 No.4
증례 : 소화기 ; 글루코사민 복용 후 발생한 약물 유발성 자가면역성 간염
권성순 ( Seong Soon Kwon ),위지완 ( Jee Wan Wee ),박정완 ( Jung Wan Park ),윤석윤 ( Seug Yun Yoon ),정승원 ( Soung Won Jeong ),장재영 ( Jae Young Jang ),진윤미 ( Yoon Mi Jin ) 대한내과학회 2013 대한내과학회지 Vol.85 No.5
글루코사민은 흔하게 사용되며 각광받는 건강 보조식품 중 하나로 항산화 효과 등이 보고되어 있으나 독성, 특히 간염에 대해서는 아직 잘 알려지지 않았다. 저자들은 글루코사민 섭취 후 간독성이 발생한 67세 여자 환자를 경험하였다. 상기 식품을 한 달 이상 섭취 후 약제 유발성 급성 자가면역 간염이 발생하였으며 간손상이 발생할 만한 다른 원인은 관찰되지 않았다. 12주간의 보존적인 치료와 자가면역 간염에 대한 치료(prednisolone과 azathioprine의 병합요법) 후 증상과 생화학적 이상 소견이 호전되었다. Herbal remedies and health foods are widely used, and their side effects have been reported. Glucosamine is a naturally occurring amino-monosaccharide and a safe health food; rarely, however, it can cause cholestatic and hepatocellular hepatitis. We describe a case of drug-induced autoimmune hepatitis after ingestion of glucosamine. A middle-aged woman who had no history of liver disease complained of jaundice after taking glucosamine. The diagnosis of drug-induced acute autoimmune hepatitis was made using the Roussel Uclaf Causality Assessment Method score based on the patient`s history and laboratory data, and percutaneous liver biopsy. After supportive care and administering prednisolone and azathiprine, the patient showed rapid improvement in clinical symptoms and laboratory findings. (Korean J Med 2013;85:503-506)
김현만,이관우,채봉남,진윤미,김윤정,이성규,홍은경,임호영,정윤석,박소윤 대한내분비학회 1998 Endocrinology and metabolism Vol.13 No.3
Primary squamous cell carcinoma of the thyroid is rare, presenting much less than one percent of all primary thyroid malignancies. Most cases have been reported in elderly patients with a history of goiter. It is necessary to differentiate between primary squamous cell carcinoma and secondary involvement from other sites. Secondary involvement of the thyroid may be more amenable to palliation or cure. The treatment of choice in primary squamous cell carcinoma is radical surgery in resectable cases, but the squamous cell carcinoma behaves aggressively and carries a uniformly poor prognosis regardless of the treatment. We had an experience of a primary squamous cell carcinoma of the thyroid in two elderly patients. These patients presented a typical feature of a primary squamous cell carcinoma of the thyroid, which has been rarely reported in Korea (J Kor Soc Endocrinol 13:446-452, 1998).
Peutz-Jeghers 증후군 환자에서 발생한 장중첩증 1예
이광재,김진홍,조성원,이태승,김헌종,함기백,진윤미,고광현,박소윤 대한소화기내시경학회 2000 Clinical Endoscopy Vol.20 No.1
Peutz-Jeghers syndrome is a rare autosomal dominant disorder defined by hamartomatous polyps of gastrointestinal tracts and the occurrence of melanin spots on the mucocutaneous surface. This syndrome has important complications such as malignant transformation, gastrointestinal bleeding, and intussusception. About 50% of patients with Peutz-Jeghers syndrome involved Intussusception. A case of Peutz-Jeghers syndrome with intussusception was recently experienced and herein reported.
김현만,이관우,신영구,진윤미,이성규,소의영,황경주,이성근,정윤석,박소윤 대한내분비학회 1998 Endocrinology and metabolism Vol.13 No.2
Insuliin secreting tumor is 70% prevalent disease in female and predoadnant in forth and sixth deeade. The incidence of insulinoma is one case per 250,000 patient-years. Insulinoma in pregnancy was extremely rare, and the prevalence was not reported. The diagnosis of an insulinoma is depend on demonstration of hypoglycemia with high insulin and C-peptide levels. Immunoreactive insulin/plasma glucose ratio0.3 in particular support the diagnosis of an insulinoma. Fetal complication would be developed because of hypoglycemia. In approximately half of the cases reported, surgical exploration was done during pregrancy, the remainder were treated after delivery. Insulinoma poses serious diagnostic and therapeutic problems when she is pregnant. We experienced a case of insulinoma in pregnancy that represented Whipples triad and was treated by surgical intervention (J Kor Soc Endocrinol 13:288-294, 1998).