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좌측 기저핵 경색 치료로 정맥내 혈전 용해술 후 발생한 조기 재발성 우측 기저핵 경색
지혜민,서지현,원유희,윤태식 대한뇌신경재활학회 2014 뇌신경재활 Vol.7 No.2
A 43-year-old man with no notable medical history was admitted due to sudden onset dysarthria and right side weakness. The man was diagnosed with acute infarction of left basal ganglia (BG) and uncontrolled diabetes mellitus (DM). After 9 hours post the thrombolysis, mental change and left side weakness symptoms were newly observed, and the man was additionally diagnosed with acute infarction in right BG.The man showed symptoms of quadriplegia and was fed through nasogastric tube. He showed motor aphasia, and no signs of phonation,but showed some indications of intact cognition.After rehabilitation therapies, the man showed marginal improvement in motor function, but still lacked any meaningful changes functionally. This is the first case of symmetric bilateral BG infarction, which one-sided infarction additionally occurred within 24 hours post the treatment of contralateral infarction through thrombolysis. Also,the features observed were atypical while the patient has no previous external causes related with bilateral BG infarction.
김소연,배하석,지혜민 대한재활의학회 2015 Annals of Rehabilitation Medicine Vol.39 No.3
Two patients with stage three secondary lymphedema of the upper extremities underwent treatment for breast cancer, including surgery, chemotherapy, and radiotherapy. They were examined with computed tomography (CT) before and after extracorporeal shock wave therapy (ESWT). We used a manual tracing method using PiViewSTAR software to calculate the volume of the upper extremities. There was a decrease in the volume of the subcutaneous compartment measured by CT before and after ESWT. CT may be helpful in determining the treatment target area of ESWT and to monitor the effect of treatment by measuring the changes in volume before and after ESWT in patients with lymphedema. Therefore, CT may have good clinical potential for treatment and follow-up in the management of lymphedema.
이헌율(Lee Hun-Yul),지혜민(Ji Hye Min) 한국여성커뮤니케이션학회 2015 미디어, 젠더 & 문화 Vol.30 No.4
본 연구는 문화산업의 발달과 함께 끊임없이 변화하고 있는 팬덤 문화 속에서 일어나고 있는 구별의 양상을 팬 생산자를 중심으로 규명, 그 자세한 동학을 연구하였다. 기존의 팬덤 연구가 팬덤을 하나의 공동체로 보고 팬덤이 하위 문화로서 다른사회 집단과 어떤 차별성을 가지고 있는가에 중점을 두고 이루어졌다면, 본 연구는 팬 생산자 상호간의 구별과 견제, 연대를 통하여 노출되는 팬덤 내부의 동학에 초점을 맞추었다. 그 결과, 트위터를 중심으로 한 사회관계망서비스(SNS)와 후기 자본주의 사회의 지식산업이 팬덤 내부 동학의 주요한 변인이 되고 있음을 확인할 수 있었다. 기존의 공동체 중심의 팬 활동을 대체하기 시작한 SNS는 팬 생산자들이 개인화를 통해 팔로워를 모으고 권력화를 이루는 주요 변인이 되고 있다. 더 나아가 이런 개인화는 전통적인 팬 공동체의 기반이었던 선물경제(gift economy)에서 벗어나 생산물을 상품화함으로써 후기 자본주의 사회의 지식산업의 경제자본화와 밀접한 관련을 보였다. 본 연구를 위하여 팬 생산자 심층 인터뷰, 트위터 텍스트 분석, 자기진술 등의 연구 방법을 사용하였다. This article is to articulate discrimination inside of fandom. Fandom, with its suffix, -dom, has been treated in a collective term. Fiske, based on Bourdieu’s concept of distinction, argues for discrimination to distinguish among fans based on each one’s knowledge and that is what this study finds among fandom activities in Korea. Traditionally community- and Internet discussion board-oriented, the Korean fandom changes its direction toward individualization. A few factors have contributed to the change: the maturing fandom culture with about 30 years of its history; the emergence of the Internet economy, especially social network services; and developing fandom commodity production. The change brings about more sophisticated discrimination among fans based on age, star, loyalty, etc. This article puts production knowledge at the center of its focus and identifies it as a key element deciding one’s status. The status, however, is ephemeral and needs to reconfirmed through various efforts of a producer, such as improving production quality and networking. This individualized free labor takes a form of what Terrranova articulates as a network cultrue in the post-industrial society. As a result, fandom labor, traditionally considered free, comes to have tumultuous relationships with its economic base, to get recognized as valuable, but to maintain its community spirit. This study is based on in-depth interviews with fan artifice producers, their twitter analysis and the fandom experience of one of the authors.
백두옹탕(白頭翁湯)의 대장암 세포주 HCT-116 항암효과와 세포자멸사에 관한 연구
김종욱,문구,박찬희,이정한,지혜민,Kim, Jong-Uk,Moon, Goo,Park, Chan-Ny,Lee, Jeong-Han,Ji, Hye-Min 대한한방내과학회 2010 大韓韓方內科學會誌 Vol.31 No.2
Objectives : To investigate the anti-cancer effect of Baekduong-tang(BDOT) against cancer cells, the signaling pathway of apoptosis was explored in human colon cancer cells. Materials and Methods : Human colon cancer cell lines, including HT-29 and HCT-116 cells, were used. Cell viability was measured by MTT assay. Apoptosis was determined by DAPI nuclei staining and flow cytometry in HCT-116 cells treated with 0.25 mg/$m{\ell}$ Baekduong-tang for 48 hrs. Results : Baekduong-tang induced the apoptosis of p53 positive HCT-116 cells with G2/M phase arrest. Treatment with Baekduong-tang led to increased expression and phosphorylation of p53 and decreased expression of CDK2 and CDK6 in HCT-116 cells. It also activated caspase-3 through caspase-10 and caspase-9 activation. Finally, Baekduong-tang induced production $H_2O_2$, superoxide anion ($O_2^-$) and NO and modulated proteins expression including SOD, NOS, Bax and Bcl-2. Conclusions : These results indicate Baekduong-tang induces apoptotic death of HCT-116 cells through G2/M phase arrest and disturbance of intracellular redox status in a p53-dependent manner.
대학생 커플 간의 성 의사소통 양상에 따른 성 태도, 성적 자율성 및 성 만족도의 상관관계에 관한 연구
이은하,이지연,정지영,강시원,한현민,김소연,김동미,방소현,박예찬,지혜민 이화여자대학교 간호과학대학 2015 이화간호학회지 Vol.- No.49
Purpose: The purpose of this study was to investigate sexual communication among college student couples and to analyze the relationship among sexual communication, sexual attitude, sexual autonomy and sexual satisfaction. Methods: Using a descriptive correlation study design, 281 college student couples were recruited through convenience random sampling from September 18th to October 3rd, 2014. Data were analyzed using average, standard deviation, percentage, t-test, ANOVA, Scheffe test, Duncan’s test and Pearson’s correlation using the SPSS 21.0 program. Results: In both genders, it is identified that high scores for sexual communication is related to sexual openness (male: R= .347, p<0.01 / female: R=.337, p<0.01) higher sexual satisfaction (male: R= .349, p<0.01 / female: R=.336, p<0.01) and sexual autonomy (male: R= .336, p<0.01 / female: R=.364, p<0.01). The same outcome is found when each male and female are grouped as a couple. Among sub-categories of sexual attitude, sexual pleasure was related to sexual communication the most in male (R=.337, p<0.01), female groups (R=.317, p<0.01) and couples (R=.402, p<0.01). Among sub-categories of sexual satisfaction, psychological factor was related to sexual communication the most in the male group (R=.342, p<0.01) and interactive factor was related to sexual communication the most in the female group (R=.317, p<0.01) and couples (R=.402, p<0.01). Conclusion: The significance of this research is that the relations of sexual communication with the other three dependent variables among each gender and couples are shown. In addition, this study suggests the importance of sexual communication between couples which will lead to healthier and better quality of sexual relationships. However, with the lack of sufficient advanced research, there are limitations of analyzing each variables divided by demographic characteristics.