1989 년 전북 서북부지역에서의 A 형 바이러스성 간염의 역학적 조사

임동석(Dong Suk Lim),조규혜(Kyoo Hye Cho),김학철(Haak Cheol Kim) 대한내과학회 1992 대한내과학회지 Vol.43 No.1

N/A Background: HAV was known as a water-borne disease and which was known aboiut a variable prevalence rate of specific antibody against hepatis A virus (anti-HAV) in differrent countries, and its prevalence of anti-HAV depend on the socio-economic state, hygiene, crowding and etc.. Method: A seroepidermiological study to detect anti -HAV was made with 802 randomly collected sera (1989) from heathy Korean who were residents in North -West area of Cheon-Buk province by radio-immuno assay (RIA, Abbort). Results: The prevalence rate of this area was high and closely related to age groups. The age-related prevalence rate was high in early infant period and then decreased after that period. The prevalence rate of anti -HAV of the period in 0-1/2 year was higher than that of 1/2-1 year. And then it was persisted untill preschool ages. But, it was sharply increased during school ages and adolescence period then plateued at>95% prevalence in young adult. The prevalence rate of ours were lower than that of Hong`s which was obserbed in Seoul Korea in 1979, especially in those age groups spanning spanning 6-18 years. Conclusion: North-West area of Cheon-Buk province might be an endemic area to HAV, and the anti-HAV that was transfered from the mother would be lost within 1 year. The infection to HAV might be occur chiefly in schoolage, The differrence suggest that there is changing of age-related prevalence rate of anti-HAV in Korea, and may be due to improvement of scioeconomic state and public health. And in furture, it might be increased the HAV susceptible popullation in Korea. The anti-HAV IgG in early infants that was transfered from their mothers might be lost within one year.

십이지장 팽대부의 융모성선종

최석채(Suck Chei Choi),송승렬(Seung Ryel Song),임동석(Dong Suk Lim),조규혜(Kyoo Hye Cho),유재규(Jae Kyu Ryu),김학철(Hak Chel Kim) 대한소화기학회 1993 대한소화기학회지 Vol.25 No.4

Villous adenoma of the ampulla of Vater Which is sometimes the cause of extrahepatic obstructive jaudice is uncommon disease. But they are important in spite of their rarity, because of frequent malignant change in the tumor as a focal or all occult tumor. Recently, the early diagnosis of ampullary tumors has become possible due to the ide application of fiberoptic endoscopy and increasing knowledge about the ampullary tumors. Although the biopsies were taken during the endoscopy, sometimes one might miss the area of malignant degeneration. But, it could increase the diagnostic accuracy by performing a hiopsy at the highly suspected site ofl malignancy, like our case in which fixed and discolorecl areas in the lesion were biopsied. So we recommed an affn.ssive endoscopic study and hypotonic duodenogram. Even thought it is diagnosed as benign, and can be treated with endoscopic pelypectorny, but we recommend the complete resection of the tumor because of high incidence of recurrence and malign ant transformati on.

원저 : 대량 객혈 환자에서 동맥색전술의 지혈효과

강정성 ( Jeong Seong Kang ),정병학 ( Byung Hak Jung ),조규혜 ( Kyoo Hye Cho ),장근 ( Keun Chang ),정은택 ( Eun Taik Jeong ),노병석 ( Byung Suk Roh ) 대한결핵 및 호흡기학회 1993 Tuberculosis and Respiratory Diseases Vol.40 No.2

소장암으로 오인된 크론병 1예

조규혜,유경훈 圓光大學校 醫科學硏究所 1998 圓光醫科學 Vol.14 No.2

Crohn's disease is a chronic, non-specific inflammatory disease of the gastrointestinal tract of unknown etiology, and used to be recognized as a rare inflammatory bowel disease in Korea, but current accumulation of sporadic case reports suggests a gradual increase of its incidence. In Crohn's disease multiple small bowel strictures may occur and there are usually inflammatory and less likely neoplastic strictures in origin and they can lead to small bowel stasis or obstruction. There have been reports of many disease processes simulating Crohn's disease such as ulcerative colitis, amebiasis, diverticulitis, tuberculosis and ischemic colitis as well as infiltrating scirrhous carcinoma have all been noted to mimic the radiologic appearance of Crohn's disease. We have experienced one patient who had manifestation of acute abdomen and diarrhea, weight loss, and abdominal CT findings that appeared large mass in the ileocecal valve area which considered carcinoid tumor, tentatively diagnosed as Cronh's disease involving the small bowel compared with large intestine and rectum.

유지 혈액 투석환자의 생존율에 관여하는 위험 인자

옥순인,조규혜,이태영,이재홍,이명수,안선호,김용성,최은경,송주홍 圓光大學校 醫科學硏究所 1998 圓光醫科學 Vol.14 No.2

We have retrospectively examined the relationship of serum albumin and creatinine in 96 hemodialysis patients to determine the risk factors for mortality. Other variables studied includied age, diabetes and dialysis time and frequency. Observed survival was computed by the Kaplan Meier method. Cox's proportional hazards model was used to determine risk predictors for mortality. Old age, diabetes, low level of creatinine, shorter dialysis time and less dialysis frequency were higher mortality risk predictors in hemodialysis patients. These findings suggest that adequate hemodialysis and improved nutrition are important in survival of patients maintained on hemodialysis.

직장류와 다른 골반저 질환의 연관

김태현,김진아,진경민,조규혜,최석채,나용호,윤권하 대한소화관운동학회 1999 Journal of Neurogastroenterology and Motility (JNM Vol.5 No.2

50세에 케톤산중 혼수를 첫 증상으로 발생한 제1형 당뇨병 1예

유경훈,백승훈,이재홍,김경년,조규혜,조정구 圓光大學校 醫科學硏究所 1998 圓光醫科學 Vol.14 No.2

Type 1 diabetes(Insulin-dependent) is caused by the selective destruction of the insulin secreting islet cells of the pancreas and is an autoimmune disease that occurs among genetically susceptible individuals most often develops in children and young adults, but sometimes in people over 40 years of age. These individuals may be characterized by autoantibodies to GAD and high-risk HLA DQ alleles, which are unlikely to be prevalent among patients with true type 2 diabetes. There are differences between type 1 patients of over 40 years at diagnosis and adult type 1 diabetic patients with onset at a younger age. There are strong evidence for humoral and cellular autoimmunity in adult type 1 diabetic patients with onset both before and after 40 years of age. The incidence of type 1 diabetes in the age group over 40 year at onset is variable to races and nations. The present study indicates that type 1 diabetes may develop at any age. Thus the life-time risk of developing type 1 is higher than hitherto expected. Adult-onset type 1 diabetes may represent a disease that is biologically distinct from youth-onset type 1, and it would be important to distinguish these two entities. A very large population base would be required to identify sufficent numbers of adult-onset type 1 cases for study of the etiology and pathogenesis of this disease. Diabetic ketoacidosis(DKA) is a common illness among individuals with insulin dependent diabetes mellitus considered largely preventable. The major metabolic derangements of type 1 diabetes are hyperglycemia, excessive ketonemia and ketonuria. Type 1 diabetes is usually believed to present acutely, and it is assumed that metabolic decompensation is sudden. DKA is an acute metabolic complication of diabetes mellitus that can be life threatening. Correct classification of diabetic patients in adulthood at the time of diagnosis is often difficult. The treatment of DKA should be started as soon as its diagnosed, and the goal of the therapy is to increase the rate of glucose utilization by insulin dependent-tissues. This case is type 1 diabetes of 50 year old woman who presented a diabetic ketoacidosis as her first symptom on a late-onset type 1 diabetes.