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두개내 내 경동맥 거대동맥류에 의한 고 프롤락틴 혈증 1예
조규혜,조정구,박옥규,김태영,노병석 圓光大學校 醫科學硏究所 1991 圓光醫科學 Vol.7 No.1-2
A case of hyperprolactinemia caused by a giant intracranial aneurysm is presented. The prolactin level was 188 ng/㎖ Systematic anterior pituitary function testing was performed. There was an abnormality in hormonal production to appropriate stimulation. The aneurysm was associated with panhypopituitarism. CT scan and MRI demonstrated round high density lesion in sellar and parasellar area and the aneurysm was confirmed by subtracted angiogram. It was possible to trap it.
조규혜,유경훈 圓光大學校 醫科學硏究所 1998 圓光醫科學 Vol.14 No.2
Crohn's disease is a chronic, non-specific inflammatory disease of the gastrointestinal tract of unknown etiology, and used to be recognized as a rare inflammatory bowel disease in Korea, but current accumulation of sporadic case reports suggests a gradual increase of its incidence. In Crohn's disease multiple small bowel strictures may occur and there are usually inflammatory and less likely neoplastic strictures in origin and they can lead to small bowel stasis or obstruction. There have been reports of many disease processes simulating Crohn's disease such as ulcerative colitis, amebiasis, diverticulitis, tuberculosis and ischemic colitis as well as infiltrating scirrhous carcinoma have all been noted to mimic the radiologic appearance of Crohn's disease. We have experienced one patient who had manifestation of acute abdomen and diarrhea, weight loss, and abdominal CT findings that appeared large mass in the ileocecal valve area which considered carcinoid tumor, tentatively diagnosed as Cronh's disease involving the small bowel compared with large intestine and rectum.
옥순인,조규혜,이태영,이재홍,이명수,안선호,김용성,최은경,송주홍 圓光大學校 醫科學硏究所 1998 圓光醫科學 Vol.14 No.2
We have retrospectively examined the relationship of serum albumin and creatinine in 96 hemodialysis patients to determine the risk factors for mortality. Other variables studied includied age, diabetes and dialysis time and frequency. Observed survival was computed by the Kaplan Meier method. Cox's proportional hazards model was used to determine risk predictors for mortality. Old age, diabetes, low level of creatinine, shorter dialysis time and less dialysis frequency were higher mortality risk predictors in hemodialysis patients. These findings suggest that adequate hemodialysis and improved nutrition are important in survival of patients maintained on hemodialysis.
50세에 케톤산중 혼수를 첫 증상으로 발생한 제1형 당뇨병 1예
유경훈,백승훈,이재홍,김경년,조규혜,조정구 圓光大學校 醫科學硏究所 1998 圓光醫科學 Vol.14 No.2
Type 1 diabetes(Insulin-dependent) is caused by the selective destruction of the insulin secreting islet cells of the pancreas and is an autoimmune disease that occurs among genetically susceptible individuals most often develops in children and young adults, but sometimes in people over 40 years of age. These individuals may be characterized by autoantibodies to GAD and high-risk HLA DQ alleles, which are unlikely to be prevalent among patients with true type 2 diabetes. There are differences between type 1 patients of over 40 years at diagnosis and adult type 1 diabetic patients with onset at a younger age. There are strong evidence for humoral and cellular autoimmunity in adult type 1 diabetic patients with onset both before and after 40 years of age. The incidence of type 1 diabetes in the age group over 40 year at onset is variable to races and nations. The present study indicates that type 1 diabetes may develop at any age. Thus the life-time risk of developing type 1 is higher than hitherto expected. Adult-onset type 1 diabetes may represent a disease that is biologically distinct from youth-onset type 1, and it would be important to distinguish these two entities. A very large population base would be required to identify sufficent numbers of adult-onset type 1 cases for study of the etiology and pathogenesis of this disease. Diabetic ketoacidosis(DKA) is a common illness among individuals with insulin dependent diabetes mellitus considered largely preventable. The major metabolic derangements of type 1 diabetes are hyperglycemia, excessive ketonemia and ketonuria. Type 1 diabetes is usually believed to present acutely, and it is assumed that metabolic decompensation is sudden. DKA is an acute metabolic complication of diabetes mellitus that can be life threatening. Correct classification of diabetic patients in adulthood at the time of diagnosis is often difficult. The treatment of DKA should be started as soon as its diagnosed, and the goal of the therapy is to increase the rate of glucose utilization by insulin dependent-tissues. This case is type 1 diabetes of 50 year old woman who presented a diabetic ketoacidosis as her first symptom on a late-onset type 1 diabetes.