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Are There Two Different Writers in You? A Study on Contrastive Rhetoric of Korean Students in the US
정윤경 ( Yun Kyung Jeong ),최호성 ( Hoh Sung Choe ) 21세기영어영문학회 2012 영어영문학21 Vol.25 No.3
The present study explored the locations of main ideas, macro-level rhetorical patterns and directness/indirectness in L1 and L2 argumentative essays written by Korean ESL students in the United States. They were divided into two groups based on their writing proficiency ability. The results indicate that most participants used English rhetoric to construct their L1 and L2 essays. They also preferred the initial location when placing their main ideas regardless of the languages they used and the varying L2 writing proficiency levels. With regard to the macro-level rhetorical patterns, they often utilized the "Explanation-Collection" style, in which the writer`s opinion is followed by equally weighted supporting reason. For argument directness/indirectness, most participants preferred to write directly. The findings of the study confirm "reverse unidirectional transfer," meaning that the rhetoric transfer actually occurred from L2 to L1.
식용버섯인 노랑느타리버섯으로부터 혈당상승억제성 α-glucosidase 저해제의 추출 및 특성
배상민,한상민,이윤혜,정윤경,지정현,이종수,Bae, Sang-Min,Han, Sang-Min,Lee, Yun-Hae,Jung, Youn-Kyung,Ji, Jeong-Hyun,Lee, Jong-Soo 한국미생물·생명공학회 2016 한국미생물·생명공학회지 Vol.44 No.2
식용버섯인 노랑느타리버섯으로부터 α-glucosidase 저해제의 추출과 정제에 대하여 연구하였다. α-glucosidase 저해제는 노랑느타리버섯 자실체를 증류수로 30℃에서 12시간 처리하였을 때 가장 많이 추출되었다. α-glucosidase 저해제를 sephadex G-100 여과 크로마토그래피와 펩신 가수분해, sephadex G-50 여과 크로마토그래피, 역상 HPLC로 정제한 결과 수율과 α-glucosidase 저해활성은 각각 12.2%와 IC<sub>50</sub> 9.10 mg/ml이었다. 정제한 α-glucosidase 저해제는 Thr-Ile-Ala-Phe-Ile-Asp (A)과 Tyr-Tyr-Ala-Ile-Gly-Asp (B)의 서열을 갖고 있는 두개의 헥사펩타이드를 함유하였고 이들의 분자량은 각각 (A)가 678.79 Da, (B)가 643.7 Da이었다. 정제한 α-glucosidase 저해제는 α-glucosidase에 대하여 혼합형 저해양상을 보였고 streptozotocin으로 유도된 당뇨 쥐모델에서 50 mg/kg과 300 mg/kg 투여시 혈당함량을 낮추어 주는, 농도 의존적 혈당상승억제 효과를 보였다. The extraction and purification of the anti-hyperglycemic α-glucosidase inhibitor from an edible mushroom, Pleurotus cornucopiae, were investigated. The inhibitor was maximally extracted when the P. cornucopiae fruiting body was treated with distilled water at 30℃ for 12 h. Purification was achieved using Sephadex G-100 and G-50 filtration chromatography, pepsin hydrolysis, and reverse-phase HPLC. The compound’s solid yield and inhibitory activity were 12.2% and 9.10 mg/ml of IC<sub>50</sub>, respectively. The purified inhibitor contained two hexapeptides with Thr-Ile-Ala-Phe-Ile-Asp (A) and Tyr-Tyr-Ala-Ile-Gly-Asp (B) sequences and molecular weights of 678.79 Da (A) and 643.7 Da (B). The purified inhibitor showed a mixed inhibition pattern to α-glucosidase and a dose-dependent anti-hyperglycemic effect in a streptozotocininduced diabetic Sprague-Dawley rat model, exhibited by decreased blood glucose levels at doses of 50 and 300 mg/kg.