비철금속제조업 생산직 남성 근로자들의 근골격계 자각증상과 관련요인

정연옥(Jeong, Yeon-Ok),조영채(Cho, Young-Chae) 한국산학기술학회 2012 한국산학기술학회논문지 Vol.13 No.8

본 연구는 한 비철금속 제조업 생산직 남성 근로자들의 인구사회학적특성, 건강관련행위 특성 및 직업관련 특성별 근골격계 자각증상호소율을 파악하고 그의 관련요인을 알아보고자 시도하였다. 조사대상은 대전광역시 소재 한 비철금속 제조업체 근로자 302명을 대상으로 하였으며, 2011년 5월 1일부터 6월 30일까지의 기간 동안에 표준화 된 무기명식 설문조사를 실시하였다. 연구결과, 연구대상자의 근골격계 질환 발생부위별 증상 호소율은 어깨부위의 증상이 42.7%로 가장 높았고, 다음은 허리부위 36.8%, 목 부위와 손/손목/손가락 부위가 각각 30.5%, 다리/발 부위 30.1%, 팔/팔꿈치 부위 20.9%의 순위였다. 인구사회학적 특성별 근골격계 자각증상 호소율은 연령, BMI가 낮을수록, 주관적인 건강상태가 좋지 않다는 군에서 유의하게 높았다. 건강관련 행위 특성별 자각증상 호소율은 질병으로 인한 결근한 적이 있다는 군, 외래 진료를 받은 적이 있다는 군, 입원진료를 받은적이 있다군, 규칙적인 운동이 비운동군, 수면시간이 부적당한 군에서 유의하게 높았다. 직업관련 특성별 자각증상 호소율은 업무의 신체적 부담정도가 힘들다 는 군, 허리를 구부리는 작업을 하는군, 직장생활에 만족하지 않는다는 군, 근속기간이 10년 이상인 군, 허리를 구부 리는 작업을 한다는 군, 반복 작업을 한다는 군에서 유의하게 높았다. 결론적으로, 생산직 남성근로자들의 근골격계 자각증상은 여러 인구사회학적 특성, 건강관련 행위특성 및 직업관련 특성과 유의한 관련성이 있었다. This study was conducted to find out the complaint rate of musculo-skeletal disorder and its related factors from male manufacturing workers at a nonferrous manufacturing industry. As for the research subjects, 302 workers selected from a nonferrous manufacturer located in Daejeon City, and as for the collection of data, a standardized anonymous questionnaire survey were conducted from May 1, 2011 to June 30, 2011. As a results, the complaint rate of musculo-skeletal disorders by each body part, the symptom of shoulders was 42.7%, the highest rate, followed by the waist, 36.8%, the neck and the hand/wrist/finger, 30.5% respectively, the leg and foot, 30.1% and arm/elbow, 20.9%. The complaint rate of musculo-skeletal disorder for the sociodemographic characteristics was significantly high as survey participants' age and BMI were low and in the group having low subjective health condition. The complaint rate of musculo-skeletal disorder for the health-related behavior characteristics was significantly high in the group having been absent from work due for diseases, in the group having received outpatient services, in the group having been hospitalized for treatment, in the group not having a regular exercise and in the group having insufficient sleeping hours. Finally, the complaint rate of musculo-skeletal disorder for the job-related characteristics was significantly high in the group suffering from the physical burden of their work, in the group working while bending at the waist and in the group carrying out repetitive tasks.

항결핵 삼제요법(HRE) 중 혈청 AST/ALT의 상승과 B형 간염의 혈청학적 지표와의 관계

손경선 ( Kyung Sun Son ),김남재 ( Nam Jae Kim ),서지원 ( Ji Won Suhr ),정연채 ( Yeon Chae Jeong ),김주옥 ( Ju Ock Kim ),김선영 ( Sun Young Kim ),이경주 ( Kyoung Joo Rhee ) 대한결핵 및 호흡기학회 1990 Tuberculosis and Respiratory Diseases Vol.37 No.3

결핵 환자에서 결핵균 베타 ( β ) 항원에 대한 혈청 항체가의 의의

서지원(Ji Won Suhr),김남재(Nam Jae Kim),홍석철(Seok Cheol Hong),정연채(Yeon Chae Jeong),김주옥(Ju Ock Kim),김선영(Sun Young Kim),백태현(Tae Hyun Paik),김화중(Hwa Jung Kim),최병태(Byong Ai Choi) 대한내과학회 1990 대한내과학회지 Vol.39 No.6

N/A We extracted beta antigen from M. tuberculosis Aoyama B and purified it from the cell extract of Mycobacterium tuberculosis by affinity chromatography with 5F3F2 monoclonal antibody. We measured the values of IgG, IgM, and IgA antibodies to this beta antigen using ELISA method in patients with tuberculosis and normal healthy controls. The results are summarized as follows: 1) The mean ELISA values of IgG and IgA antibodies to purified beta antigen in the serum of 73 tuberculous patients and 100 normal controls were 0.5560±0.2879 and 0.2177±0.1394, 0.3732±0.2011 and 0.1530±0.1272 (optical density: O.D.), respectively. This difference between the tuberculosis patients and normal controls was statistically significant (p<0,001). 2) On the results of sputum AFB stain, patients with negative AFB, 1+, 2+, and 3+ AFB findings showed significantly elevated levels of IgG antibodies to beta antigen in the value of 0.4930±0.2300, 0.7884±0.3560, 0.5736±0.3820, and 0.5310±0.1680, respectivly, when compared to that of the normal controls. Elevations of IgA antibodies to beta antigen were noted in patients with 1+, 2+, and 3+ AFB on smear staining with the value of 0.2510±0.1550, 0.2540±0.1370, and 0.2440±0.1240 when compared to that of the normal controls. 3) The mean values of IgG and IgA antibodies to purified beta antigen in patients with moderately advanced pulmonary tuberculosis were 0.5425±0.3580, 0.2128±0.1620, and in patients with far advanced pulmonary tuberculosis, 0.5336±0.2793 and 0.2721±0.2210, which were more significantly elevated than in the normal controls of 0.3732±0.2911 and 0.1530±0.1272, respectively(p<0.05). 4) In patients with superficial cervical tuberculous lymphadenitis, the mean values of antibody to purified beta antigen were not significantly different from that of the normal controls. 5) In patients with tuberculous pleurisy, the mean value of IgG antibody to purified beta antigen was elevated to 0.5520±0.4090 compared to 0.3732±0.2011 of the normal controls (p<0.005). 6) The mean values of antibodies to purified beta antigen follwing treatment showed a desreased tendency, but there was no statistical significance. In conclusion, patients with tuberculosis showed statistically significant elevations of IgG and IgA antibodies to purified beta antigen, and the measurement of these values may be useful for the diagnosis of tuberculosis-related diseases.

항결핵 6개월 단기요법의 성과 고찰

서지원,정연채,김남재,홍석철,김주옥,김선영,노흥규 충남대학교 의과대학 지역사회의학연구소 1990 충남의대잡지 Vol.17 No.1

To evaluate the effect of 6-month short term antituberculosis chemotherapy with INH, Rifampin, Ethambutol, and Pyrazinamide(2HREZ/4HRE) in the patients with pulmonary and/or extrapulmonary tuberculosis, the authors prescribed 2HREZ/4HRE regimen in 79 tuberculosis patients for 6 months with measuring the sputum staining for AFB, chest X-ray findings, recurrence rates and possible side reactions of the treatment. The result were as follow; 1. Pulmonary Tuberculosis 1) Among the 56 pulmonary tuberculosis patients who had taken 2HREZ/4HRE regimen. 32 patients showed initial positivity in sputum AFB smear stain(57.2%). Negative conversion occurred usually within 2 months after initiation of chemotherapy and the mean period of negative conversion was 1.4 months. 2) Among the 56 pulmonary tuberculosis patients, chest X-ray finding changed in 41 patients (37.21%). From these 41 patients 39 patients showed continuous improvements in chest X-ray finding, though 3 patients showed initial aggravation in spite of continuous medication. The remainder 2 cases aggravated due to the failure of treatment. 3) Treatment failure occurred in 2 patients (3.57%) during the chemotherapy among 56 patients of pulmonary tuberculosis and they were infected with secondary drug-resistant strains of M. tuberculosis. 2. Extrapulmonary tuberculosis. Among 8 patients with tuberculous pleurisy and 15 patients with superficial tuberculous lymphadenitis, there were no evidence of treatment failure after completion of antituberculosis chemotherapy for 6 months with 2HREZ/4HRE regimen. 3. Follow-up study was performed from 6 months to 50 months after completion of antituberculosis chemotherapy and the relapse was not noted in both pulmonary and extrapulmonary tuberculosis patients group during this period. 4. Serum AST/ALT elevated in 9 patients(11.4%) during the treatment and this occurred usually within 3 months after the initiation of antituberculosis chemotherapy. However treatment interruption occurred in 2 patients (2.5%) due to the development of hepatitisone due to drug-induced hapatitis and the other due to type B viral hepatitis. In conclusion, we could find this 2HREZ/4HRE 6-months short-term antituberculosis regimen is effective and could be recommanded as a promising regimen for the treatment of tuberculosis.