http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
진행성 비소세포폐암에 대한 Cisplatin , Etoposide 치료 효과
이경주(Kyoung Joo Rhee),남재만(Jae Man Nam),손경선(Kyung Sun Son),김선영(Sun Young Kim) 대한내과학회 1988 대한내과학회지 Vol.35 No.5
N/A Thirty patients with stage III non-small cell lung cancer were treated with a combination chemotherapy consisting of Etoposide, 100 to 120 mg/m² i. V. on days 1 -3; and Cisplatin, 60 mg/m²i.v. on day 1, repeated at 21-day intervals. Nineteen patients with stage III non-small cell lung cancer who refused treatment were followed via telephone and letters. The initial symptoma of the patients were cough (39%), chest pain (14%), dyspnea (12%), hemoptysis (8%), hoarseness (6%), palpable mass (6%) and others. Survival rates of 3 months, 6 months, and 1 year were 53%, 26%, and 11%, respectively in the untreated group and 97%, 87%, 45% in the treated group, respectively. Of 16 patients treated with chemotherapy alone, 1 (16 %) achieved complete remission and 4 (25%) achieved partial remission. Of 14 patients treated with chemotherapy and radiotherapy, 3 (21%) achieved complete remission and 5 (36%)achieved partial remission. The overall response rate in treated patients was 43% (complete remission 13%, partial remission 30%). Analysis of the various prognostic factors disclosed that good performance status and non-squamous cell type showed good response rates. The major toxicities were nausea and vomiting (62%), alopecia (100%), anemia (25%), leukopenia (23%), and thrombocytopenia (2%).
급만성 호흡기감염증에 대한 Ciprofloxacin의 임상효과에 대한 연구
이경주,남재만,서지원,김선영 대한화학요법학회 1988 대한화학요법학회지 Vol.6 No.2
Ciprofloxacin is a new generation of DNA gyrase inhibitor and has a broad antibacterial spectrum that includes the majority of Enterobacteriaceae, p. aeroginosa, Hemophilus, and many gram positive cocci including methicillin-resistant S. aureus. An clinical trial was performed to evaluate the efficacy and safety of ciprofloxacin in 33 patients with respiratory tract infection. The treatment was successful in 100% in acute RTI, 85% in chronic RTI. Adverse reaction was observed in 2 patients which was GI disturbance and itching.
급· 만성 호흡기감영증에 대한 Ciprofloxacin의 임상효과에 대한 연구
이경주,남재만,서지원,김선영 中央醫學社 1988 中央醫學 Vol.53 No.12
Ciprofloxacin is a new generation of DNA gyrase inhibitor and has a broad antibaterial spectrum that includes the majority of Enterobacteriaceaea. P. aeruginosa, Hemoiphilus, and many gram positive cocci including methicillin-resistant S. aureus. An clinical trial was performed to evaluate the efficacy & safety of ciprofloxacin in 33 patients with respiratory tract infection. The treatment was successful in 100 % in acute RTI, 85 % in chronic RTL Adverse reaction was observed in 2 patients which was GI disturbance and itching.
김선영,이경주 충남대학교 의과대학 지역사회의학연구소 1989 충남의대잡지 Vol.16 No.1
Assessment of disease activity in pulmonary tuberculosis is difficult when AFB is not demonstrated in smear or culture of specimen. To elucidate the usefulness of urinary neopterin as an activity index of pulmonary tuberculosis, urinary neopterin and creatinine ratio were measured in 24 normal healthy controls, 8 inactive pulmonary tuberculosis and 16 active pulmonary tuberculosis by high-performance liquid chromatograpy. Urinary neopterin creatnine ratio in normal healthy control and inactive pulmonary tuberculosis were 1.15±0.63nmol/㎎ of Cr AND 0.515±0.63nmol/㎎ of Cr, respectively. Urinary neopterin/creatinine ratio in total active pulmonary tuberculosis patient was 4.62±4.91nmol/㎎ of Cr. In minimal active pulmonary tuberculosis, the ratio was 5.49±6.56nmol/㎎ of Cr and in moderately advanced active pulmonary, the ratio was 3.35±3.08nmol/㎎ of Cr and in far advanced active pulmonary, the ratio was 5.12±4.47nmol/㎎ of Cr The difference of mean urinary neopterin levels between minimal, moderately difference of mean urinary neopterin levels between nomal controls and active pulmonary tuberculosis was statistically significant(P<0.005). It is suggested that urinary neopterin level could be an useful index of disease activity in pulmonary tuberculosis.
김선영,김주옥,손경선,이경주 대한내과학회 1987 대한내과학회지 Vol.32 No.2
Various tumor markers such as CEA., ACTH., Calcitonin and PTH in patient with lung cancer are clinically useful in number of ways: to aid in differential diagnosis, disease staging, to provide an indicator of response to therapy and disease recurrence. In order to evaluate clinical significance of serum PTH in patient with lung cancer, serum PTH level are measured and analyzed in 171 patients who were admitted to Chung-Nam National University Hospital from January 1984 to June 1986. The results were as follows; 1) The value of serum PTH was significantly higher in the patient with lung cancer (mean value; 837.95pg/ ml) compared with normal controls (mean; 524pg/ml) p$lt;0.02. 2) (1) The mean value of serum PTH in patient with squamous cell cancer (103 patients) was 835.95pg/ml and 92 patients (60%) among them were higher than normal controls. (2) The mean value of serum PTH with small cell cancer (37 patients) was 772.86pg/ml and 22 patients(59%) were higher than normal controls. (3) The mean value of serum PTH. in patient with adenocarcinoma (19 patients), Large cell cancer (8 patient), undifferentiate carcinoma (4 patient) were 814.17pg/ml, 520pg/ml, 375pg/ml and 12 patients (62%)., 2 patients (25%), 2 patients (50%) were higher than normal controls, respectively. 3) The mean vlaue of serum PTH was 1037.85pg/ml in metastasis to bone that is higher than 694.12pg/ml in metastasis to liver or 770.3pg/ml in without metastasis, but statistically not significant. 4) In the 37 patients who improved following chemotherphy, mean value of serum PTH is 832.43pg/ml at diagnosis. It is gradually decreased to 681.89pg/ml, 632. 14pg/ml according to follow up check after chemotherphy but statistically not significant. 5) No significant hypercalcemia is developed.
박성규,고광선,김선영,조인성,이경주,배일훈,박찬권,백상현 대한내과학회 1990 대한내과학회지 Vol.39 No.2
Lymphangioleiomyomatosis is a rare disease of women, usually of childbearing age, characterized by the proliferation of benign but atypical smooth muscle cells in the walls of the lymphatics of the lower respiratory tract, pleula, mediastinum, and retroperitoneum. The disease is clinically manifested by recurrent chylous pleural effusion, Pneumothorax, or ascites and hemoptysis. We experienced a case of pulmonary 1ymphan-gioleiomyomatosis in a 30-year-old female patient who had suffered from recurrent pneumothorax associated with normal pregnancy, so we report it with a brief review of the literature.
혈장반출법으로 호전된 혈전성 혈소판 감소성 자반증 1 예
안성구,고광선,조인성,이경주,배일훈,이혜림 대한내과학회 1991 대한내과학회지 Vol.40 No.6
Thrombotic thrombocytopenic purpura is a relatively rare syndrome of uncertain etiology, characterized by thrombocytopenia and microangiopathic hemolytic anemia. Most patietns have either fever, neurologic manifestations, or renal abnormalities. Thrombotic thrombocytopenic purpura was considered a rapidly progressive disase with a high mortality. However, recent reports indicate that most patients recover by improvement of treatment method. The pathologic finding is that hyaline thrombi, composed of aggregated platelets, occlude arterioles and capillaries of virtually every tissue. Although endothelial cell proliferation may be observed in proximity to the lesions, inflammatory reactions and vasculitis are not observed. We experienced a patient treated with steroids, anti-platelet agents, and fresh frozen plasma which had little therapeutic effect. But clinical and labor a brief review of the literature.