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정민재(Chung, Min-Jae),곽동경(Kwak, Tong-Kyung),김혜영(Kim, Hye-Young),강명희(Kang, Myung-Hee),이정숙(Lee, Jung-Sug),정해랑(Chung, Hae Rang),권세혁(Kwon, Sehyug),황지윤(Hwang, Ji-Yun),최영선(Choi, Young-Sun) 한국영양학회 2018 Journal of Nutrition and Health Vol.51 No.1
본 연구는 생애주기별 영양지수 중 노인 대상 영양지수(Nutrition Quotient for Elderly, NQ-E) 개발을 목표로 수행되었다. 노인의 식행동과 영양섭취 관련 문헌, 국민건강영양조사 자료, 국가 영양정책 및 권고사항, 전문가 대상 심층면접을 통해 식품섭취영역에서 18개 문항, 식행동 · 식습관 영역에서 23개 문항의 총 41개 문항으로 구성된 파일럿 조사용 체크리스트를 개발하였다. 노인 265명을 대상으로 1일의 식사섭취조사와 체크리스트 설문조사를 수행하고, 체크리스트 평가항목과 식사섭취조사 결과인 영양섭취 수준 간의 상관관계가 높은 24개 항목으로 전국단위 조사용 체크리스트를 도출하였다. 전국단위 조사는 주민등록인구통계자료를 활용하여 기본 층화변수로 6개 권역을 설정하여 권역별로 성별, 연령군별 노인 인구수를 기준으로 비례 배분하여 총 1,000명을 대상으로 면대면 조사를 수행하였다. 탐색적 요인분석을 실시하여 노인 영양지수 평가항목을 19개 항목의 4개 요인으로 분류하고, 확인적 요인분석을 통해 구성타당도를 검증하였다. 4개 요인을 식행동, 균형, 다양, 절제의 영역으로 구분하였고, 구조방정식 모형을 이용해 추정된 경로계수를 바탕으로 전문가 의견을 수렴하여 영역별 가중치를 적용하였는데, 영역별 가중치는 각각 0.3, 0.2, 0.2, 0.3으로 수렴하였다. ‘식행동’ 영역에는 음식을 씹는데 불편한 정도, 우울정도, 건강에 대한 자각, 건강한 식생활 노력, 식사 전 손 씻기, 운동시간의 6개 항목, ‘균형’ 영역에는 우유 및 유제품 섭취빈도, 과일 섭취빈도, 간식 섭취빈도, 물 섭취빈도의 4개 항목, ‘다양’ 영역에는 달걀 섭취빈도, 생선이나 조개류 섭취빈도, 채소류 섭취빈도, 콩이나 콩제품 섭취빈도, 하루 식사빈도, 혼자 식사하는 빈도의 6개 항목, ‘절제’ 영역에는 단음식 또는 달거나 기름진 빵 섭취빈도, 가당음료 섭취빈도, 라면류의 섭취빈도의 3개 항목으로 구성되었고, 표준화된 경로계수가 항목의 가중치로 적용되었다. 전국단위 조사대상자의 NQ-E 평균 점수는 57.6점이었고, 영역별 점수는 식행동 55.0점, 균형 41.4점, 다양 50.0점, 절제 76.5점이었다. 본 연구에서 개발된 노인 영양지수, NQ-E는 노인의 식사의 질과 식행동이 양호한지 판정할 수 있으며, 식행동, 균형, 다양, 절제의 4가지 영역으로 점수 산출이 가능하므로 노인의 체계적인 영양관리에 다양하게 활용 가능할 것이다. Purpose: The purpose of this study was to develop a valid instrument for measuring the dietary quality and behaviors of Korean elderly. Methods: The development of the Nutrition Quotient for Elderly (NQ-E) was conducted in three steps: item generation, item reduction, and validation. The 41 items of the NQ-E checklist were derived from a systematic literature review, expert in-depth interviews, statistical analyses of the fifth Korean National Health and Nutrition Examination Survey data, and national nutrition policies and recommendations. Pearson’s correlation was used to determine the level of agreement between the questionnaires and nutrient intake level, and 24 items were selected for a nationwide survey. A total of 1,000 nationwide elderly subjects completed the checklist questionnaire. The construct validity of the NQ-E was assessed using confirmatory factor analysis, LISREL. Results: The nineteen checklist items were used as final items for NQ-E. Checklist items were composed of four-factors: food behavior (6 items), balance (4 items), diversity (6 items), and moderation (3 items). The standardized path coefficients were used as the weights of the items. The NQ-E and four-factor scores were calculated according to the obtained weights of the questionnaire items. Conclusion: NQ-E would be a useful tool for assessing the food behavior and dietary quality of the elderly.
4 cm 이하의 단일결절 간세포암종에서 고주파열치료와 경동맥화학색전술의 효과 비교
양민재 ( Min Jae Yang ),안소연 ( So Yun An ),문은준 ( Eun Joon Moon ),이민석 ( Min Suk Lee ),황주안 ( Joo An Hwang ),정재연 ( Jae Youn Cheong ),원제환 ( Je Hwan Won ),김재근 ( Jai Keun Kim ),왕희정 ( Hee Jung Wang ),조성원 ( Sung 대한간학회 2009 Clinical and Molecular Hepatology(대한간학회지) Vol.15 No.4
Carcinoma, Hepatocellular, Radiofrequency ablation, Chemoembolization, Therapeutic, 간세포암종, 고주파열치료, 경동맥화학 색전술 Background/Aims: Radiofrequency ablation (RFA) is an established curative therapeutic modality for unresectable hepatocellular carcinoma (HCC), and transarterial chemoembolization (TACE) has been used as a palliative treatment for inoperable HCC. It is still unknown whether RFA and TACE are equally effective for improving the survival of patients with unresectable HCC that is amenable to either treatment. The aim of this retrospective study was to compare the clinical impacts of two treatments, and analyze the prognostic factors for recurrence and survival. Methods: Ninety-three patients with a single HCC smaller than 4 cm who showed complete responses (complete ablation or complete lipiodol tagging) after treatment with RFA (n=43) or TACE (n=50) between January 2002 and February 2009 were investigated. Univariate and multivariate analyses were performed for 13 potential prognostic factors using the Cox proportional-hazards model. Results: The time-to-recurrence rates at 1, 2, and 3 years after treatment were 32.9%, 44.3%, and 55.4%, respectively, for the RFA group, and 42%, 68.3%, 71.7% for the TACE group. The probability of survival at 1, 2, and 3 years was 97.7%, 77.4%, and 63.1%, respectively, for the RFA group, and 95.9%, 76.1%, and 60.2% for the TACE group. The time-to-recurrence and overall survival rates did not differ significantly between the two treatment groups. A multivariate Cox proportional-hazards model revealed that a tumor size larger than 3 cm and lower serum albumin levels were independent risk factors for recurrence, and that being male, being seropositive for hepatitis B surface antigen, and having a higher serum albumin level were independent favorable prognostic factors for survival. Conclusions: TACE and RFA exhibited similar therapeutic effects in terms of recurrence and survival for patients with a single HCC smaller than 4 cm, if they could exhibited complete responses. (Korean J Hepatol 2009;15:474-485)
딥러닝 기법을 이용한 대동맥 동맥경화성 플라크 판별에 관한 연구
조유희(You Hee Cho),방혜진(Hye Jin Bang),박종원(Jong Won Park),조정선(Jung Sun Cho) 대한기계학회 2022 大韓機械學會論文集A Vol.46 No.2
고령층의 사망원인 중 높은 비율을 차지하고 있는 뇌졸중, 심장질환은 갑작스럽게 발생하여 사망에 이를 수 있으므로 조기 진단하여 지속적인 관리가 필요하다. 고위험성 질병을 진단하기 위해서는 의료 영상을 이용한 의료진 판독을 통해서 수행되어야 하지만 판독 시간이 많이 소요되거나 의료진에 따라 판독 의견이 달라지는 경우가 발생하고 있다. 본 연구에서는 뇌졸중의 주요 원인인 대동맥 동맥경화성 플라크 상태를 분류하고 영역을 예측할 수 있는 컨볼루션 오토인코더(convolution autoencoder)와 유넷(U-Net) 모델을 수립하여 판독 시간을 단축시키고 정확도를 높이고자 한다. Stroke and heart disease, which account for a high percentage of the causes of death amongst the elderly population, can occur suddenly leading to death. Hence, early diagnoses and continuous management are required. High-risk diseases should be diagnosed through medical personnel using established medical techniques. However, it is time consuming to decide on a diagnosis or the opinion may differ depending on the medical professional. This study aims to shorten the diagnosis period and provide high accuracy diagnoses by establishing the semi-supervised convolution autoencoder and the U-Net models that can classify aortic atherosclerotic plaque conditions and predict the primary locations for stroke occurrence.
ZCT 방식을 이용한 두 개의 컨버터 병렬 운전 시 고장 검출 및 분리
정민재(Min-Jae Jung),박상은(Sang-Eun Park),손승찬(Seung-Chan Sohn),이진(Jin Lee),성세진(Se-Jin Seong) 전력전자학회 2000 전력전자학술대회 논문집 Vol.2000 No.11
The paper presents the fault detection and isolation of two DC-DC converters parallel operation by ZCT method. Two experimental prototype converters were designed and implemented for evaluation of fault tolerant system. The experimental results show that fault detection and isolation circuit works very well.
악성 위험지수 (Risk of Malignancy Index) 1을 이용한 골반내 종양의 분석
박정우 ( Jung Woo Park ),황성욱 ( Sung Ook Hwang ),박지현 ( Jee Hyun Park ),이병익 ( Byoung Ick Lee ),이정훈 ( Jeong Hoon Lee ),김기원 ( Ki Won Kim ),김경미 ( Kyoung Mi Kim ),정민재 ( Min Jae Jung ),윤내리 ( Nae Ri Yun ),송은섭 ( 대한폐경학회 2013 대한폐경학회지 Vol.19 No.1
Objectives: To assess the ability of risk of malignancy index (RMI) 1 to discriminate between benign and malignant pelvic masses. Methods: Between January 2007 and December 2010, 547 women with pelvic masses were evaluated. Their medical records are reviewed here retrospectively. The sensitivity, specificity and positive and negative predictive values of the cancer antigen (CA) 125 level, ultrasound findings and menopausal status in the prediction of malignant pelvic masses were calculated and compared individually or combined using the RMI 1. Results: The receiver operating characteristic (ROC) curves of CA 125, the ultrasound score and the RMI 1 were all found to be relevant predictors of malignancy. ROC analysis of the RMI 1, CA 125 serum levels, ultrasound score and menopausal status showed areas under the curves of 0.795, 0.782, 0.784 and 0.594, respectively. The RMI 1 was found to be statistically significantly correlated with menopausal status (P = 0.001), while not statistically significantly correlated with CA 125 (P = 0.628) or the ultrasound score (P = 0.541). The RMI 1 at a cut-off of 150 - with a sensitivity of 77.9%, specificity of 81.1%, positive predictive value of 51.7% and negative predictive value of 93.4% - showed the highest performance in determining the malignant tendency of pelvic masses. Conclusion: Accepting a RMI 1 cut-off value of 150 results in statistically more significant diagnostic criteria than menopausal status for the discrimination of benign and malignant pelvic masses. (J Korean Soc Menopause 2013;19:18-25)