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김영규(Young Kue Kim),윤규욱(Kue Wook Yoon),손원경(Won Kyeung Sohn),윤준(Jun Yoon),고준성(Joon Sung Ko),전대준(Dae Jun Jeon),안병건(Byoung Kuen An),서재희(Jae Hee Seo) 대한산부인과학회 2002 Obstetrics & Gynecology Science Vol.45 No.3
A case of metastatic malignant melanoma of ovary with malignant melanoma of skin is rare. The tumor was discovered 17months following excisional biopsy of left hand for malignant melanoma of the skin. Primary ovarian malignant melanomas are extremely rare and are thought to originate in teratomas. Ovarian melanoma without evidence of residual teratoma must be considered metastatic even in the absence of a previously identifiable cutaneous or mucocutaneous lesion. We had experienced a case of metastatic malignant melanoma of ovary and presented with a brief review of literature.
울산지역에서 주폐경기 ( Perimenopause ) 여성의 골다공증 유병률과 연관인자
김영일(Young Il Kim),박재후(Jae Hoo Park),이종수(Jong Soo Lee),김진우(Jin Woo Kim),양승오(Seoung Oh Yang),전대준(Dae Joon Jeon),김문찬(Mun Chan Kim),정태흠(Tae Heum Jeong),이윤구(Yoon Gu Lee),이병두(Byoung Doo Rhee) 대한내과학회 2002 대한내과학회지 Vol.62 No.1
N/A Background: Osteoporotic fractures pose a major public problem, not only in Western populations but also of increasing significance in Asian populations. However, most previous studies for the prevalence of osteoporosis in Korea were carried out from the data of hospitalized or out-patient based subjects, hospital staff, healthy volunteers and so forth. The purpose of present study was to evaluate the normative data of bone mineral density (BMD) in Korean young and perimenopausal women and to determine the prevalence and risk factors of low bone mass, including osteoporosis and osteopenia in a community- based population. Methods: In 1999, a baseline survey was carried out in the Dong-gu of Ulsan city, a urban area but located in seashore of southeastern Korea. The selected community sample of 3,822 inhabit ants (all were women aged 49-54 years) were chosen. We studied 1,629 women among them and 127 healthy women aged 20-35 years. BMD of lumbar spine and femur was measured using dual-energy X-ray absorptiometry. For analysis of risk fact ors, those were excluded who was the current or recent user of estrogen and who had osteoporosis related disease or unknown menopause due to previous hysterectomy. Thus, 1,020 subjects were analysed for the association of low BMD and risk factors. Significant determinants of BMD were investigated using univariate and multiple regression analysis. Results: When our young normal data were used, 9.8% for the lumbar spine and 1.4% for the femoral neck of our study population (n=1,629) were classified as osteoporosis. Among them, the menopausal status of above 1,020 subjects had independent association with low BMD (T-score<-1.0) of both lumbar spine (odds ratio=4.71 in postmenopause, p <0.001) and femoral neck (odds ratio=2.86 in postmenopause, p <0.001). In premenopausal women (n=507), weight and age of menarche were associated independently with low bone mass, including osteoporosis and osteopenia of both lumbar spine and femoral neck. In postmenopausal women (n=513), weight and duration since menopause were associated independently with low bone mass of both lumbar spine and femoral neck. Also, daily amount of calcium intake had significant association (regression coefficient =0.047; p <0.05) independently with BMD of femoral neck. Conclusion: The result s of this population-based study suggest that it is import ant to prevent bone loss and screen the BMD in women aged 49-54 years with menopause, low body weight, late menarche, prolonged duration since menopause, low calcium intake.(Korean J Med 62:11- 24, 2002)