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장웅기(Woong Ki Chang),김동준(Dong Joon Kim),윤택중(Taek Jung Yoon),김진환(Jin Hwan Kim),주상언(Sang Aun Joo),유재영(Jae Young Yoo),최보율(Bo Youl Choi),이수진(Soo Jin Lee),김병렬(Byong Reol Kim) 대한내과학회 1996 대한내과학회지 Vol.51 No.6
N/A Objectives: This study was carried out to estimate the incidence rate of the stomach cancer in a small to medium sized community (Chuncheon Si and Chuncheon Kun, Kangweon Do) of about 230,000 population. Methods: The study period was from Jan. 1. 1992 to Dec. 31. 1993 and the subjects were confined to newly diagnosed cases living in Chuncheon area during this period. The data collected through medical records from 9 medical facilities located in Chuncheon area and capable of pathologic (Gastroendoscopy) or roentgenographic (Upper gastrointestinal series) diagnosis among 12 medical facilities. Results: 1) The total cases of newly diagnosed stomach cancer during the study period (2 years) were 163. The frequency of stomach cancer by age was in order of 70s (48 cases, 29.4%), 60s (41 cases, 25.1%), 50s (38 cases, 23.3%) years of age in all, 50s (32 cases, 27.8%), 60s (28 cases, 24.3%), 70s (27 cases, 23.5%) in male and 70s (21 cases, 43.8%), 60s (13 cases, 27.1%), 50s (6 cases, 12.5%) in female. The male to female ratio in total stomach cancer cases was 2.4:1. 2) The annual crude incidence rate of stomach cancer was estimated to be 35.7 persons per 100,000 persons in all, 49.9 and 21,4 persons per 100,000 persons in male and female, respectively. 3) The annual age standardized incidence rate of the stomach cancer for the Korean population was 35.7 persons per 100,000 persons in all, 44.1 and 18.4 persons per 100,000 persons in male and female, respectively. 4) The cumulative incidence rate of the stomach cancer for age span 0-69 years was 4.8% in male, 1.3% in female and that for age span 0-79 was 9.5% in male, 3.8% in female. 5) The major symptoms of stomach cancer patients were the epigastric pain (69.9%), indigestion (32.5%), and weight loss (30.0%). Most patients had suffered from the symptoms more than one month before the first visit to hospitals or clinics, suggesting the diagnosis tend to be delayed. 6) The proportion of early gastric cancer was 24 persons (14.7%) among 163 persons of stomach cancer patients. Conclusion: We estimate the incidence rate of the stomach cancer in a small to medium sized community (Chuncheon city and Kun, Kangweon Do) of about 230,000 population from Jan. 1. 1992 to Dec. 31. 1993 and report the characteristics of the stomach cancer patients.
구연 / 제 1 회의장 / 위장관 5 : Helicobacter pylori 감염의 위험요인에 대한 환자 - 대조군 연구
장웅기(Woong Ki Chang),김동준(Dong Jun Kim),김학양(Hak Yang Kim),김종혁(Jong Hyuk Kim),박충기(Choong Kee Park),유재영(Jae Young Yoo),김미경(Mi Kyung Kim),최보율(Bo Youl Choi),최호순(Ho Soon Choi),박경남(Kyung Nam Park),김현자(Hyun Ja 대한소화기학회 1999 대한소화기학회 추계학술대회 Vol.1999 No.-
B형 간염 예방접종 효율에 관한 연구 - 한 농촌지역에서의 혈청학적 표지자에 대한 분석
송관욱(Kwan Uk Song),김훈(Hun Kim),고문수(Moon Soo Koh),장웅기(Woong Ki Chang),김동준(Dong Jun Kim),박충기(Choong Kee Park),유재영(Jae Young Yoo),최보율(Bo Yool Choi) 대한내과학회 1999 대한내과학회지 Vol.57 No.6
N/A Background : The objectives of this study are to determine the positive rate of HBV serologic markers and infection rate, and to evaluate the efficiency of hepatitis B vaccination. Methods : Study subjects included 905 persons in 1988-1989 and 744 persons in 1993-1994 living in typical rural communities in Korea. Three serologic markers(HBsAg, anti-HBs, anti-HBc) were tested by radio-immunoassay(RIA). Supplemental informations were collected by self-administered questionnaire and interview on age, sex, history and frequency of vaccination. Results : 1) Among non-vaccinees, HBsAg, anti-HBs, anti-HBc positive rates and infection rate in 1993-1994/1988-1989 were 5.4%/6.5%, 49.1%/45.9%, 48.3%/44.1% and 60.6%/54.5% respectively. The infection rate showed a trend of continuous increase as the age increased, while statistically significant increase was seen over age 20. 2) Overall vaccination rate was 18.1% in 1988-1989 and 37.9% in 1993-1994, showing statistically significant increase in vaccination rate. The rate in younger age groups were higher than in older groups in 1988-1989, but there was no difference by age groups in 1993-1994. Among vaccinees, anti-HBs only positive group occupied 42.7% in 1988-1989 and 41.3% in 1993-1994. HBs Ag negative and anti-HBc positive group occupied 26.2% in 1988-1989 and 36.73% in 1993-1994. Conclusion : 1) Among non-vaccinees, HBsAg positive rate was decreased, but the hepatitis B infection rate was not decreased. 2) The test for selection of eligible person of vaccination and education program for completion of vaccination schedule must be reevaluated to improve the efficiency of hepatitis B vaccination. (Korean J Med 57:994-1005, 1999)
임화중(Hwa Joong Yim),백근욱(Keum Wook Baek),윤석부(Seok Bu Woon),장웅기(Woong Ki Chang),김동준(Dong Jun Kim),김홍기(Hong Ki Kim),채승완(Seung Wan Chae),박영의(Young Euy Park) 대한소화기학회 1994 대한소화기학회지 Vol.26 No.2
The Peutz-Jeghers syndrome is an autosornal dominant hereditary disease characterized by hamartous polyps of the gastrointestinal tract and by mucocutaneous melanin deposits. This syndrome is clinically important because of the complications caused by gastrointestinal pol- yps and of an increased risk for the development of cancer. W e experienced a case of develop- ing an adenocarcinoma of the stomach in patient with Peutz-Jeghers syndrome, who had mucocutaneous pigmentations and gastric, small intestinal and large intestinal polyps for seven years. (Korean J Gastroentero11994; 26: 337-342)
위암 및 Helicobacter pylori 감염의 위험인자로서 염분 섭취의 역할
경태영(Tae Young Kyong),김학양(Hak Yang Kim),채경수(Gyeoung Soo Chae),유희승(Hee Seung Yoo),박수종(Soo Jong Park),김종혁(Jong Hyeok Kim),장웅기(Woong Ki Chang),김용범(Yong Bum Kim),박충기(Choong Kee Park),남은숙(Eun Sook Nam),유재영( 대한내과학회 1998 대한내과학회지 Vol.55 No.2
N/A Objectives: Gastric cancer is one of the most important malignancy of the gastrointestinal tract. High salt intake has been suggested as a risk factor of gastric cancer and promoting Helicobocter pylori infection. Few studies have been addressed about the relation between excessive salt intake and gastric cancer. This study was performed to investigate the relation of high salt intake to H. pylori infection and gastric cancer. Methods . Between May 1996 and July 19%, hospitalized patiaits with epigastric pain or dyspepsia were prospectively recruited. Patients with underlying diseases which could reduce kidney function were excluded. Salt consumption was estimated by the urine sodium to creatinine ratio(U-Na/Cr) on fresh single urine sample. Gastric cancer was diagnosed by endoscopic biopsies. H. pylori infection was evaluated by CLOtest. Gastric cancer was classified histologically by Lauren classification. Results: Ninety seven patients, 52patients with gastric cancer and 45patients with chronic gastritis were enrolled. There was no statistically significant difference in the sodium to creatinine ratio between gastric cancer group(173.60±123, range; 21-665.2) and chronic gastritis group(164.02±138, range; 20.4-482.7)(p=0.361). In gastric cancer, the sodium to creatinine ratio was not different between CLOtest positive and negative group(p=0.201), and among intestinal, diffuse and mixed type(p=0.419), either. Conclusion: This study does not support the causal relation of high salt diet on gastric carcinogenesis. There is no significant difference in H, pylori infection rate between CLOtest positive group and negative group.
간경변 환자에서 Mosaic-Like Pattern의 임상적 의의
김진봉 ( Jin Bong Kim ),김동준 ( Dong Joon Kim ),오순옥 ( Soon Ok Oh ),문상호 ( Sang Ho Moon ),김성중 ( Sung Jung Kim ),백광호 ( Gwang Ho Baik ),장웅기 ( Woong Ki Chang ),이진 ( Jin Lee ),이명석 ( Myeng Seok Lee ),김학양 ( Hak Ya 대한소화기학회 2003 대한소화기학회지 Vol.41 No.1
Background/Aims: Mosaic-like pattern (MLP), one of the elementary lesions of portal hypertensive gastropathy, is common in patients with liver cirrhosis. The aim of this study was to examine the association between the severity/location of MLP and severity of the liver disease. Methods: We carried out 177 endoscopic examinations in 139 cirrhotic patients and examined the severity of MLP on the basis of the New Italian Endoscopy Club classification. Additionally, we classified the MLP according to its location. Then, the association between severity/location of MLP and Child-Pugh classification was investigated. Results: Child class A, B, and C were observed in 82, 57, and 38 cases, respectively. Severity grades of MLP of none, mild, moderate, and severe were observed in 4.5%, 70.1%, 21.5%, 4.5% of the 177 examinations, respectively. The location of MLP in the high body, mid-body, low body, and antrum was confirmed in 3.6%, 38.1%, 36.9%, and 16.7% of the cases, respectively. MLP was not observed in 4.8% of the cases. The severity and location of MLP revealed statistically significant correlation with the Child-Pugh classification (p=0.001/0.000, respectively). Moreover, the severity and location of MLP were also correlated each other (p=0.000). Conclusions: Not only the severity but also the location of MLP has a strong correlation with the severity of liver cirrhosis. As the liver function deteriorates, the location of MLP tends to extend toward the antrum from the high body. (Korean J Gastroenterol 2003;41:33-40)
대장암 및 대장용종 환자에서 상부위장관 병변의 동반 빈도
신운건(Woon Geon Shin),김학양(Hak Yang Kim),허필석(Pil Seog Heo),이자영(Ja Young Lee),김억(Aukk Kim),김진봉(Jin Bong Kim),서중산(Joong San Suh),이진헌(Jin Hyon Lee),김종혁(Jong Hyeok Kim),장웅기(Woong Ki Chang),김동준(Dong Joon Kim) 대한소화기학회 2001 대한소화기학회지 Vol.38 No.5
Background/Aims: It is unclear whether further evaluation for upper gastrointestinal tract is needed in the patients with colorectal lesions. We conducted this study to investigate the prevalence of simultaneous upper gastrointestinal lesion in the patients with colon cancer or polyp. Methods: Data of 904 consecutive patients who received both colonoscopic and gastroduodenoscopic examination from July 1997 to August 2000 were analyzed retrospectively. Gastroduodenal mucosal lesions such as gastric ulcer, duodenal ulcer, gastric polyp or gastric cancer were classified as clinically significant lesions. We compared the prevalence of upper gastrointestinal mucosal lesions between the patients with and without colonic lesions. Results: Fifty-five (25.9%) of 212 patients with colonic lesions and 87 (12.6%) of 692 patients without colonic lesions had simultaneous gastroduodenal lesions. The patients with colonic polyp or cancer had more gastroduodenal lesions than those without colonic lesions (p<0.05). According to histologic finding of colonic lesion, the prevalence of gastroduodenal lesions was higher in the patients with hyperplastic polyp (p<0.05) and tubular adenoma (p<0.05) than in the patients without colonic lesions. Conclusions: It is suggested that many of the patients who have colonic hyperplastic polyp and tubular adenoma may have simultaneous colonic and gastroduodenal lesions. Therefore, upper gastrointestinal endoscopy should be performed in the patients with colon neoplasia. (Korean J Gastroenterol 2001;38:336-341)