EAF 더스트-점토계의 중금속 용출 및 안정화에 미치는 pH의 영향

이지영,이기강,김유택,강승구,김정환,Lee, Jee-Young,Lee, Ki-Gang,Kim, Yoo-Taek,Kang, Seung-Gu,Kim, Jung-Hwan 한국결정성장학회 2006 韓國結晶成長學會誌 Vol.16 No.2

유해한 중금속을 다량 함유하는 EAF(electric arc furnace) 더스트를 세라믹 원료로 재활용하기 위해서 EAF 더스트, EAF 더스트-점토에 대해서 pH와 혼합비에 따른 중금속 용출농도의 변화를 분석하였다. 소성과정 중에서 발생하는 중금속의 휘발량을 소지 내의 중금속 이온의 총량을 측정하여 평가하였으며 TCLP(toxicity characteristic leaching procedure)분석을 통해 중금속 이온의 안정화 정도를 평가하였다. EAF 더스트-점토 슬러리의 pH를 10으로 조절하였을 경우에 습식혼합 여액중의 중금속 이온의 농도가 가장 낮은 값을 가졌다. pH 10의 슬러리에 대해서 혼합비와 소성온도에 따른 소지내 중금속 이온의 총량을 측정한 결과 소성온도와 EAF 더스트의 함량이 증가할수록 중금속의 휘발이 증가하였으며, 점토의 혼합비가 증가할수록 중금속 이온의 휘발이 억제되었다. TCLP 분석결과 점토의 혼합비와 소성온도가 증가할수록 중금속의 용출은 감소하였으며 중금속의 용출농도는 기준치 이하로 안정화되었음을 확인할 수 있었다. To recycle the electric arc furnace (EAF) dust as a ceramic raw materials, the leaching concentrations of heavy metals (Zn, Pb, Cr, Cd) were analysed with various pH and mixing ratios for EAF dust and EAF dust-clay mixtures. The evaporation amounts of the some heavy metals were evaluated by measuring their total concentrations in the sintered bodies of EAF dust-clay mixtures with various mixing ratio and sintering temperature. Toxicity characteristic leaching procedure (TCLP) test was conducted for evaluating the chemical stabilities of the heavy metal elements. Leaching concentrations of heavy metal ions shows minimum leaching concentration at the pH 10. Evaporation amount of heavy metals in the sintered bodies were evaluated for the mixtures of pH 10 depenidng on mixing ratio and sintering temperature. Evaporation of heavy metal components were increased with increasing the sintering temperature and contents of the EAF dust. The evaporation of the heavy metal components in EAF dust was effectively suppressed by increasing the clay content. The leaching concentrations of heavy metal components were decreased with increasing clay content and temperature.

개 심장사상충 추출액 투여에 의한 Anaphylactoid Reaction

이지영,송근호,권현주,김명철,윤효인,김덕환,Lee, Jee-young,Song, Kun-ho,Kwon, Hyun-ju,Kim, Myung-cheol,Yun, Hyo-in,Kim, Duek-hwan 대한수의학회 2003 大韓獸醫學會誌 Vol.43 No.3

This study was performed to clarify the induction possibility of anaphylactoid reactions by the administration with the heartworm extracts, and, if any, to elucidate different virulences in terms of the protein concentrdtions and sexes of Dirofilaria immitis. Twenty three clinically healthy D. immitis-free adult dogs were used in the present study. The experimental animals were divided into 5 groups. Group A (5 heads) was administered with an female heartworm extract containing 0.1 g/dl protein concentration. Group B (4 heads) was administered with an male heartworm extract containing 0.1g/dl protein concentration. Group C (5 heads) was administered with an female heartworm extract containing 0.2 g/dl protein concentration. Group D (4 heads) was administered with an male heartworm extract containing 0.2 g/dl protein concentration. Group E (5 heads) was administered with an female heartworm extract containing 0.4 g/dl protein concentration. The changes of clinical symptoms and vital signs (body temperature, heart rate and respiration rate) were examined before and 5 minutes, 15 minutes, 30 minutes, 1 hour, 2 hours and 24 hours after injection with the extracts, respectively. In addition, the changes of hematological values (RBC, PCV and total leukocytes counts), serum chemical values (ALP and CK) were determined. It was considered that heartworm extract could induce anaphylactoid reaction and adult female heartworm extract was more affective than those of adult male heartworm extract in the changes of clinical symptoms, vital signs, hematological values and serum chemical values.

해암단이 수종의 암세포에 미치는 항암 효과

이지영,오혜경,류한성,김남재,정원용,오현아,최혁재,윤성우,류봉하,Lee, Jee Young,Oh, Hye Kyung,Ryu, Han Sung,Kim, Nam Jae,Jung, Won-Yong,Oh, Hyun-A,Choi, Hyuck Jai,Yoon, Seong Woo,Ryu, Bong-Ha 대한암한의학회 2015 大韓癌韓醫學會誌 Vol.20 No.2

Objective : The objective of this study was to investigate the anti-tumor activity of the complexed herbal formula, Haeamdan (HAD). Methods : Seven Cancer cell lines, LoVo, MCF-7, AGS, Sarcoma 180, HL-60, NCI-H69, LL/2, were prepared and the cytotoxicity was assessed by 3-(4,5-dimethylthiazol-2yl)-2,5-dephenyl tetrazolium bromide (MTT) assay. HAD was applied with various concentrations from 0.1 to 1.0 mg/ml to figure out the appropriate dosage. ICR male mice were intraperitoneally implanted with Sarcoma 180 and divided into 8 species for each group. Control group was treated with normal saline, positive control group was treated with cyclophosphamide 8mg/kg, and experimental group was treated with HAD 1g/kg. Results : Among seven cancer cell lines, HAD exhibited strong cytotoxic activities to followed four cancer cell lines, that is, Sarcoma 180, HL-60, NCI-H69, and LL/2. These cytotoxic activity was expressed under 0.50 mg/ml of IC50 under 0.1~1mg/ml of OBW. When Sarcoma 180 cancer cell was implanted in ICR male mice and treated with the HAD, HAD prolonged the median overall survival for 3.6 days, from 17.5 to 21.1 days. Conclusion : HAD showed strong cytotoxicity to the cancer cells, Sarcoma 180, HL-60, NCI-H69, on in vitro study and it showed anti-tumor activity in vivo with the peritoneal cancer mice by prolonging the median survival for 3.6 days. Further researches would be expected to support the anti-tumor efficacy of HAD.

온백원이 암세포에 미치는 항암활성 효과

이지영,오혜경,류한성,김남재,정원용,오현아,최혁재,윤성우,류봉하,Lee, Jee Young,Oh, Hye Kyung,Ryu, Han Sung,Kim, Nam Jae,Jung, Won-Yong,Oh, Hyun-A,Choi, Hyuck Jai,Yoon, Seong Woo,Ryu, Bong-Ha 대한암한의학회 2015 大韓癌韓醫學會誌 Vol.20 No.2

Objective : The objective of this study was to investigate the experimental efficacy of anti-tumor activity of the complexed herbal formula, Onbaekwon (OBW), which was derived from the literature of Traditional Korean Medicine, Dongeuibogam. Methods : Nine Cancer cell lines, LoVo, MCF-7, HepG2, AGS, A549, NCI-H69, HL-60, Sarcoma 180, LL/2, were prepared and the cytotoxicity was assessed by 3-(4,5-dimethylthiazol-2yl)-2,5-dephenyl tetrazolium bromide (MTT) assay. Four of them, NCI-H69, HL-60, Sarcoma 180, and LL/2, showed strong cytotoxic activities and they were additionally undergone flow cytometry to find out their effects on apoptosis. ICR male mice were implanted with Sarcoma 180 intraperitoneally and divided into 8 species for each group. Control group was treated with normal saline, positive control group was treated with cyclophosphamide 8mg/kg, and experimental group was treated with OBW 1 g/kg. Results : Among 9 cancer cell lines, NCI-H69, HL-60, Sarcoma 180, and LL/2, expressed less than 0.10 mg/ml of $IC_{50}$ under 0.1~1mg/ml of OBW. NCI-H69, HL-60, Sarcoma 180, and LL/2, showed dose-dependent efficacy of apoptosis. When Sarcoma 180 cancer cell was implanted in ICR male mice and treated with the OBW, they prolonged the median overall survival for 0.8 days, from 17.5 to 18.3. Conclusion : OBW showed strong cytotoxicity to some cancer cells, which are NCI-H69, HL-60, Sarcoma 180, and LL/2, and its apoptotic activity was dose-dependent. OBW prolonged the median survival of mice implanted with Sarcoma 180. Further researches would be expected to support the efficacy of OBW.

진행성 대장직장암 환자군에 있어서 5-FU 혹은 capecitabine의 최적 시간 치료법에 대한 체계적 고찰 : 메타분석

이지영,오혜경,류한성,윤성우,Lee, Jee Young,Oh, Hye Kyung,Ryu, Han Sung,Yoon, Seong Woo 대한암한의학회 2015 大韓癌韓醫學會誌 Vol.20 No.1

Background : The purpose of this study is to investigate the efficacy and safety of the circadian delivery schedule of fluorouracil or capecitabine based chemotherapy for advanced colorectal cancer. Patients and methods : A meta-analysis was performed using individual data from eight international randomized clinical trials, especially phase II or III trials, comparing 5-fluorouracil, or capeticabine in chronomodulated or conventional schedule. The data from 8 studies was composed of 692 patients receiving chronomodulated chemotheray and 684 patients receiving conventional chemotherapy. The main end point was response rate. Results : Response rate was insignificantly different from each group (RR 1.14, 95%CI 0.74-1.74, p=0.55). Overall survival and progresseion-free survival were not significant either. Chemotherapy induced anemia, diarrhea, and nausea/vomiting were worse in the chronotherapy group, with statistic significance respectively. On the other hand, chemotherapy induced thrombocytopenia, stomatitis, peripheral neuropathy, and dermatotoxicity were better but they were not statistically significant results. Conclusions : Patients lived longer but not significantly on chronomodulated chemotherapy rather than on conventional chemotherapy. Patients on chronomodulated chemotherapy experienced adverse events more. The chronomodulated chemotherapy schedule needs adjustment of its delivery schedule and further research is required.

점토와 전기로 제강분진의 콜로이드/계면 특성 분석

이지영,이기강,김유택,강승구,김정환,Lee, Jee-Young,Lee, Ki-Gang,Kim, Yoo-Taek,Kang, Seung-Gu,Kim, Jung-Hwan 한국결정성장학회 2006 韓國結晶成長學會誌 Vol.16 No.2

중금속 이온의 용출거동은 콜로이드/계면 성질에 의존하는데, 이를 알아보기 위해 ICP와 SEM 분석을 하였다. 전기로 제강분진에 포함된 중금속은 '양쪽성 금속'으로 pH 10에서 중금속이 가장 적게 용출되는 것을 알 수 있었고 pH 8보다 pH 12에서 중금속 이온이 상당량 용출되어 나왔다. 그리고 전기로 제강분진에 점토를 첨가함으로써 중금속 이온의 용출이 감소하는 것을 알 수 있었다. 특히 pH 12의 경우에 pH 8에 비해서 중금속 이온의 용출이 큰 폭으로 감소하였으며 콜로이드계면 성질 관찰 결과, 점토의 경우 pH 12에서 점토에서 녹아나온 Si 수화물이 점토 입자표면을 둘러싸고 있음을 관찰할 수 있었다. 전기로 제강분진과 점토의 혼합 슬러리에서 pH 8의 경우보다 pH 12에서 중금속 이온의 농도가 크게 감소한 것은 PSHP의 형성에 의한 것으로 사료된다. The leaching behavior of heavy metal ions with pH and colloid/interface property was analyzed by ICP and SEM. The heavy metals in EAF dust are 'amphoteric metal' and the heavy metal ions leached a little at pH 10. And the leaching concentrations of heavy metals at pH 12 were higher than the that at pH 8. The leaching concentrations of heavy metal ion were decreased with adding the clay to the EAF dust. Especially, the leaching concentrations of heavy metal ion were effectively decreased at pH 12. The observation of colloid/interface properties shows that the soluble silicon hydroxide from clay at pH 12 was precipitated at the surface of the heavy metal and clay particles. This silicon hydroxide precipitates were named the PSHP. The leaching concentrations of heavy metal ion were effectively decreased by the formation of PSHP when adding the clay to the EAF dust and controlling the pH of the slurry at 12.

논문 : 담화 원리를 바탕으로 한 제안 기능 교육 내용 구성

이지영 ( Jee Young Lee ) 국제한국어교육학회 2006 한국어 교육 Vol.17 No.3

In this study, I examined the characteristics of the communication function expressed in practical conversation and I discussed the plan of its application to the Korean Language Education. In order to teach the communication function more effectively, we should make a practical application of the contents on the communication function education based on the principles of discourse. I also examined the application of the education contents, laying stress on the suggestion function, as one between various communication function. The suggestion function is one of the communication functions which are frequent in everyday conversations. In the suggestion function I clarified how is the interaction of the participants in the conversation shown, and which forms of language are used, and I searched for the plans of the practical application to the Korean language education. The composition of the education contents should reflect the types of the conversation which is following the difference between the expression of the suggestion and its purposes. The following constructions of the suggestion conversation are reflecting the contents: [suggestion] → [accepting a suggestion] / [suggestion] → [rejection of the suggestion] / [suggestion] → [accepting a part of the suggestion] / [suggestion] → [opposite suggestion] / [deriving of the suggestion] → [suggestion] → [a accepting suggestion]. (Sangmyung University)

일반 논문 : 인쇄 광고 표제 표현의 형식과 기능 연구 -교육 광고 표제 표현을 중심으로-

이지영 ( Jee Young Lee ) 한국어교육학회(구 한국국어교육연구학회) 2011 국어교육 Vol.0 No.135

The purpose of this study is to analyze printed advertising language. For this purpose, this study examine the types of form and function of headline in printed advertising language. The form of headline in printed advertising language has been classified into phrases and clauses form, sentence form, discourse form. Sentence form divided into five types. Discourse form classify into quotation and explanation, explanation and quotation, opinion versus opinion, question and answer, question and explanation. The function of headline in printed advertising language has been classified question function, request function, wish function, explain function, greeting function, time limitation function, compensation offer function, interesting function, discourse start function.

한국어 학습자를 위한 대우 표현 연구

이지영(Lee, Jee Young) 동악어문학회 2013 동악어문학 Vol.60 No.-

이 연구에서는 한국어 학습자를 위한 대우 표현 연구의 방향과 교육 내용 구성의 방향에 관하여 논의하였다. 한국어 학습자를 위한 대우 표현 연구는 대우 표현의 형식 정보와 사용 정보를 함께 연구해야 한다. 또한 한국어 대우 표현 교육정보를 적극적으로 활용하여 한국어 학습자의 의사소통 능력을 향상시켜야 함을 강조하였다. 나아가 한국어 대우 표현의 내용 구성을 관계 중심 내용 구성과 상황중심 내용 구성으로 구분하여 논의하였다. Korean honorific expression is one of the most significant features of Korean language for Korean learners. In this study, a different approach to honorific expression education research for Korean language learners was presented. The traditional approach in which the categories are divided into subject respect, object respect, and hearer respect. The other approach is focusing separately on the sentence’s final endings, pre-final endings, pronouns, nouns, propositions, verbs, and so on. To make Korean language learners speak honorific expression fluently, they need the ability to use practical communication skills as well as be able to communicate naturally. Communicative competence consist of four components as linguistic competence, sociolinguistic competence, discourse competence, strategic competence. Therefore, honorific expression research of the field of Korean language education should be achieved using effective contents. Thus, the result of honorific expression research for Korean language education should be able to use information about honorific expression. To use the information about honorific expression, I discussed the focal point of phonological information, syntactic information, semantic information, and pragmatic information. When Korean language learners use the Korean honorific expression it is important to understand the relationship between the conversation participants. Status, age, gender, and intimate between participants, depending on the relationship, because Korean language learners can choose a variety of expressions. The most important criteria in determining the relationship of conversation participants that is determined by the relationship of the family status or age.

학문 목적 한국어 교육을 위한 문법 연구의 방향

이지영(Lee, Jee-young) 원광대학교 인문학연구소 2016 열린정신 인문학연구 Vol.17 No.1

Recently, Korean language education"s aspect is becoming more various and subdivided, according to the objective of Korean language learners. Therefore, a new approach to grammatical research should be achieved for Korean language learners for academic purpose. In this study, a different approach to elements of grammar education research for Korean language learners for academic purpose was presented. Research about building educational information, relevance between grammar elements and academic communication ability, the connection between educational contents and methods etc. In the end, grammar research found that the intimate connection between practical use and language ability are factors in helping improve academic communication skills in the field of Korean grammar education for foreigners.