여름철의 돼지관리와 방역대책

이주목,Lee, Ju-Mok 대한양돈협회 1989 養豚 Vol.11 No.6

분자간의 상호간섭을 고려한 2성분계 흡착의 확률적 모델링

이승목,이주광 ( Seung Mok Lee,Ju Goang Lee ) 한국물환경학회 1996 한국물환경학회지 Vol.12 No.2

A Markov process coupled with interaction between molecules is developed to simulate bisolute adsorption kinetics. This model is relatively simple in that estimates of all model parameters except interaction parameters are obtained from single solute experiment. Transient behavior of molecules can be evaluated by analytically solving a system of the governing ordinary differential equations of the present stochastic model. Adsorption rate profile is not affected by interaction parameters at low concentration range.

강릉시 식수계중 휘발성 유기화합물질 ( VOCs ) 의 분포

이주광,이승목,윤이용 ( Ju Goang Lee,Seung Mok Lee,Yi Yong Yoon ) 한국물환경학회 1996 한국물환경학회지 Vol.12 No.3

A survey of Volatile Organic Compounds(VOCs) was conducted in the Kangnung City raw water, treated water and groundwater from Mar. 1994 to Dec. 1994. Four VOCs. 1,1,1- trichloroethane, carbon tetrachloride, trichloroethylene and tetrachloroethylene, were detected below detection limit level. Among those, 1,1,1-trichloroethane, carbon tetrachloride and trichloroethylene were detected at trace and frequently. Trichloroethylene was contaminated in the highest level among detected four VOCs. The mean concentrations of trichloroethylene were 1.15㎍/ℓ of the raw water, 3.30㎍/ℓ of the treated water and 0.47㎍/ℓ of the groundwater. respectively. The concentration levels of the VOCs from the raw water and the treated water were increased from winter to summer, while this trend cannot be found in groundwater.

위에 발생한 위장관 간질성 종양의 임상병리학적 특성과 치료성적

류제석,이성렬,최새별,박성수,이주한,김승주,김종석,채양석,목영재,Ryu Je-Seock,Lee Sung-Ryul,Choi Sae-Byeol,Park Sung-Soo,Lee Ju-Han,Kim Seung-Joo,Kim Chong-Suk,Chae Yang-Seok,Mok Young-Jae 대한위암학회 2005 대한위암학회지 Vol.5 No.1

배경: 위장관 간질성 종양(GISTs)은 위장관계에 발생하는 간엽성 종양이다. 위장관 간질성 종양은 면역조직화학 검사에서 c-kit 단백 발현의 양성을 나타내며 그 임상적 경과는 매우 다양하다. 저자들은 위장관 간질성 종양의 임상병리학적 특성을 고찰하고 예후 인자를 평가하기 위하여 후향적 연구를 시행하였다. 대상 및 방법: 본 연구는 고려대학교 의과대학 외과학교실에서 1996년부터 2003년까지 위장관 간질성 종양으로 수술적 절제를 시행한 40명의 환자를 대상으로 하였다. 종양의 크기와 핵분열 정도에 따라 저위험도 집단(23예), 고위험도 집단(17예)으로 분류하였으며 두 군간 임상병리학적 특성, 면역조직화학 검사 결과 및 예후를 비교 분석하였다. 결과: 환자의 평균 연령은 $61.3\pm11.1$세이었으며 남녀비는 1:1,1이었다. 임상병리학적 소견으로는 수술 전 임상 증상이 있었던 경우와 수술 전에 조직학적으로 진단이 되었던 경우, 종양의 크기가 클수록, 핵분열이 많을수록, 종양의 성상이 궤양을 동반하거나 괴사를 보일 때, 고위험군에 포함되는 빈도가 높았다. 단변량 분석 결과, 종양의 크기, 핵분열 정도, 궤양 및 괴사 소견 그리고 내시경적 초음파 이상소견이 통계학적으로 의미가 있는 인자들로 나타났으며, 다변량 분석을 시행한 결과 핵분열 정도가 생존율에 영향을 미치는 독립적인 예후 인자로 나타났다. 관찰 기간 중 8예에서 재발하였으며 STI-571(imatinib mesylate, $Gleeveo^{R}$)을 사용한 4예는 현재까지 생존하고 있으며 사용하지 않은 4예 중 2예는 질환이 진행하는 양상을 나타내었고, 나머지 2P는 사망하였다. 결론: 위에서 기원한 위장관 간질성 종양에서 종양의 크기, 궤양 및 괴사 소견은 생존율에 영향을 주는 임상병리학적 소견이며, 핵분열 정도는 유용한 예후 인자라고 할 수 있다. STI-571은 재발 혹은 전이 환자에 있어 치료 효과를 나타내므로 술후 치료에 적용하는 것이 예후 향상에 기여하리라 생각된다. Purpose: Gastrointestinal stromal tumors (GISTs) are mesenchymal neoplasms of the gastrointestinal tract. GISTs are positive for the expression of c-Kit protein at immunohistochemistry, and their clinical presentations vary. This retrospective study was performed to evaluate the clincopathologic characteristics of GISTs and to define the prognostic factors. Materials and Methods: 40 patients who underwent a complete resection of a GIST during the period $1996\~2003$ at the Department of Surgery, Korea University College of Medicine, were studied. We divided them into low- and high-risk. groups by using tumor size and mitotic count: 23 cases were low risk, and 17 were high risk. Clinicopathologic features, immunohistochemical findings, and prognoses were compared between the low- and the high-risk groups. Results: The mean age of the 40 patients was $61.3\pm11.1$years, and the male-to-female ratio was 1:1.1. There was no significant difference in age and sex between the groups. A comparative analysis revealed tumor size, mitotic count, clinical symptoms, preoperative pathologic diagnosis, ulceration, and necrosis to be variables that had statistically significant differences between the high- and the low-risk groups. In the univariate analysis, tumor size, mitotic count, ulceration, necrosis, and abnormal endoscopic ultrasound findings were associated with disease-free survival, but in the multivariate analysis, mitotic activity was the only independent factor associated with disease-free survival. 8 patients had recurrences during the follow-up period, and four of them were treated with STI-571 (imatinib mesylate, $Gleevec^{(R)}$). The treated patients have survived until now; however, two of non-treated patients died from disease progression. Conclusion: Based on this study, tumor size, ulceration, and necrosis are significant factors affecting survival, and mitotic activity may be a useful prognostic marker. STI-571 may be used in an adjuvant setting because the drug has shown anticancer activity in patients with recurrence or metastasis.

철도차량용 선형유도전동기 축소형 모델의 등가회로 파라미터 도출 및 추진력 제어 알고리즘 검증 연구

박찬배(Chan-Bae Park),목형수(Hyung-Soo Mok),이주(Ju Lee) 대한전기학회 2010 전기학회논문지 Vol.59 No.7

Authors conducted a deduction of some parameters using the magnetic equivalent circuit method and a verification study of the thrust force control algorithm of a rotary-typed small-scaled linear induction motor for a railway transit. In a LIM, it is possible to express the parameters of the magnetic equivalent circuit into a function of the shape of the secondary aluminium plate and the airgap between the LIM primary core and the secondary aluminium plate. It means that the LIM properties can be changed considerably by the shape of the secondary aluminium plate and the airgap between the LIM primary core and the secondary aluminium plate. So, authors analyzed a tendency of changes of the magnetic equivalent circuit parameters and the LIM characteristics by changing of the airgap of the secondary aluminium plate of a rotary-typed small-scaled LIM. And authors conducted a verification study of the indirect vector control algorithm with constant slip frequency by using the rotary-typed small-scaled LIM tester set on the basis of the calculated LIM parameters. Finally authors accomplished a research on applicability for LIM railway transit.

기선권현망(機船權現網)의 연구(硏究)-5

이병기 ( Byoung Gee Lee ),서영태 ( Young Tae Su ),이주목 ( Ju Mok Lee ) 한국어업기술학회 1980 수산해양기술연구 Vol.16 No.1

LEEP으로 치료한 자궁 경부 상피내 종양에서 고위험 인유두종 바이러스 감염 및 절제면 병변여부의 의의

이상수,박은주,이동헌,남주현,김용만,김종열,김종혁,목정은,나준희,이주학,김영탁 대한부인종양 콜포스코피학회 1999 Journal of Gynecologic Oncology Vol.10 No.3

This study evaluated the degree and the frequency of cervical lesions after treatment with LEEP(loop electrosurgical excision procedure) in patients with abnormal Pap smears according to the presence or absence of high-risk HPV infection. From June 1994 to May 1997, eighty patients who showed CIN or chronic cervicitis on LEEP specimens were followed up with Pap smears. The histologic results and follow-up Pap smear data were analyzed. In all cases HPV test by Hybrid Capture assay was performed. Those with neoplastic lesion underwent follow-up Pap smears at least for 1 year with 3 month interval after LEEP. In HPV-positive group(N=38), 63.2% of the cases revealed neoplastic lesion(CIN) on final histologic evaluation, and in HPV-negative group(N=42) 54.8% of the cases did(p=0.26). HPV-positive group represented 25.0%(6/24) of abnormal Pap smear result on follow-up, which is higher than that of HPV-negative group(4.3%; 1/23), showing significant difference (p$lt;0.05). There was a significant difference in the rate of neoplastic lesion developed during follow-up between resection margin-positive group and resection margin-negative group on LEEP(p=0.04). Also, HPV-positive group had significantly higher chance to show abnormal Pap smear results during follow-up(p=0.02). In conclusion, HPV test and margin status were shown to be useful parameters to predict the recurrence or persistence of CIN lesion treated by LEEP.