다발성 대장암 간전이 환자의 간절제를 위한 새로운 시도

주종우,김형철,임철완,신응진,조규석,유기원,송옥평,홍대식,박성진,조준희,이혜경,김희경,권계원,고은석 순천향의학연구소;Soonchunhyang Medical Research Institute 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

Multiple bilobar liver matastases (MBLM) are the main cause of low resectability in the colon cancer liver metastases. The authors experienced one case of initially non-resectable colon cancer liver metastases. He was curatively and safely treated with a two-stage hepatectomy using the new method of future remnant liver volume growing. A 54-year-old man was referred to our department with the sigmoid colon cancer combined with MBLM, which were checked in two small metastatic lesions in the left lobe and five large sized lesions in the right lobe in the computed tomogram (CT). A laparoscopic assisted anterior resection was primarily performed. We performed the 1^(st) stage hepatectomy 3 weeks after the colon resection. Intra-operative Ultrasonogram (US) found 9 small superficial metastatic lesions in the left lobe. All that lesions were completely removed by non-anatomical wedge resection. An occlusion ballon catheter was placed in the right portal vein through a small branch of the inferior mesenteric vein at that time. The future remnant liver volume was sufficiently increased 3 weeks after the 1^(st) hepatectomy. A right hepatectomy was safely performed 22 days after the 1^(st) hepatectomy. The patient received a regional chemotherapy (interleukin2 based immuno-chemotherapy through hepatic artery) for 4 months, then received 9 cycles of systemic chemotherapy (biweekly Oxaliplation, leucovorin, plus 5-fluorouracil) without any recurrence evidence.

釜山市 都心地內 駐車場의 實態調査分析

金熙鍾,吳錫氣 동아대학교 공과대학 부설 한국자원개발연구소 1977 硏究報告 Vol.2 No.1

A Study on parking problems in metropolitan regions in Korea is a recent concern. In case of Busan, although the master plan for traffic was established in 1974 the and survey for the parking problems were not considered. In this study, the area for this survey was limitted to 3 on-street parking places in Busan C.B.D. The data Survey was carried out for 8 hours from 9.00 A.M. to 17.00 P.M. on 15th oct. 1976. The method of this survey was performed through continuous observation and interview by each vehicles. The Contents of the survey are necessary basic data for the establishment of parking plans such as parking time, parking purpose, parking use and kinds of vehicles, etc. The results of this study are summarized as follows; ① Average parking time~61.7 min. (By the continuous observation method) ② Parking purpose Business and Commercial;88.8% ③ Method of parking use~Daily thicket use:77.1%, Monthly ticket use:22.9% ④ Major kind of vehicle~Taxi:91.1% ⑤ Average parking index~l.30 ⑥ Average rotation index~9.5.

2, 2'-Methylene-bis-(3,4,6,-trichlorophenoxy acetic acid)(MTPA)의 肝디스토마症의 治療效果(第一報)

金鍾石,金和雄,金重暎 慶北大學校 醫科大學 1972 慶北醫大誌 Vol.13 No.2

The effect of MTPA was observed in 173 clonorchiasis patients who visited to the department of pharmacology, Kyungpook national university, school of medicine, from Sep., 1969 to Jun,, 1971 and 20, Mar. , 1972. In 173 patients, 162 patients had normal liver function, 10 patients were complicated with acute hepatitis and one of the patients had been inserted T tube into his common bile duct since 7 months after operation for bile stone. MTPA was administered oraly in daily dose of 7∼15㎎/㎏, which was divided into three equal part and given after each meal. To each patient the drug was given for 4 or 5 cures and one cure was composed of 6 days of drug administration and the interval between each cure was 10 days. The effect of drug was estimated with counting the number of eggs of clonorchis in the feces by the MGL method, the results were expressed as "negative", completly disappeared, and "80% diminution", number of the eggs reduced more than 80% than before treatment. Besides egg count, general symptoms and liver function before and after medication, and side effects induced by drug were also observed. The results obtained as follows. 1) In 51 patients treated with 10㎎/Kg/day for 4 or 5 cures, egg-negative rate was 49% and 80% diminution was 37%. 2) In 31 patients treated with 7 ㎎/Kg/day for first cure and than 15㎎/Kg/day for 3 or 4 cures, egg-negative rate was 58.1% and 80% diminution was 35.5%. 3) In 80 patients given in dose of 10㎎/Kg/day for first cure and then 15㎎/Kg/day for 3 cures or 15㎎/Kg/day for 4 cures, the egg-negative rate were 64.7%, and 69.5% and 80% diminution rate were 29.4%, and 23.9% respectively. 4) In the patients administered with MTPA, the gerneral symptoms and signs such as fatigue, anoraxia, indigestion etc. and hepatomegaly were improved. 5) In 10 patients complicated with acute hepatitis and administered with 3㎎/Kg/day for first cure and continued by 7㎎/Kg/day second cure and then 15㎎/Kg/day for 3 cures, 7 of them were egg-negative, 2 of them were 80% diminution. 6) Side effects induced by drug were gastric pain, abdominal pain, diarrhea, dizziness, headache, fatigue and fever, But the side effects were so mild that discontinuance of administration of drug was not necessary in most cases. 7) In the patient inserted with T tube while administered with 7㎎/Kg/day of MTPA, clonorchis sinensis flew out from the T tube in living, but with 15㎎/Kg/day, clonorchis sinensis flew out in dead. From above results we think that MTPA is a useful drug for treatment of clonorchiais, and 15㎎/Kg/day is enough to kill clonorchis sinensis in the body.

옥시칼본계 화합물의 포오틀랜드 시멘트 광물에 대한 흡착거동

김창은,최진호,유종석 연세대학교 산업기술연구소 1983 논문집 Vol.15 No.2

The rheological properties of the cement mineral-sodium gluconate-water system were investigated by determining the adsorbed amount of sodium gluconate, the sedimentation velocity of cement particles, and viscosity of the cement paste. IR and SEM were used to analyze the adsorbed phase on cement minerals. The results of experiment were as follow: 1. In the case of containing gypsum, the adsorbed amount of sodium gluconate on OPC could be calculated from the sum of that on each mineral component. 2. In general, the fluidity of the cement paste was increased with the equilibrium concentration. 3. There were maximum values of the amount adsorbed and viscosity at equilibrium concentration of 0.3% for C₃A in the solution system. 4. The adsorbed phase of sodium gluconate on C₃A could be identified by the IR analysis with the wavelength region of 3200??(-OH), 2800??(C-H), and 1600??( ?? ) 5. As shown in microstructure analysis with SEM, the layered type structure of hydrated C₃A could incorporate with polar compound or ionic species to form a interlamella complex. Due to the large surface area of layed structure of C₃AHx, the extraordinary high amount of gluconate anion adsorbed C₃A matrix could be well explained also comparing with hydrated C₃S.

Fine달린 Heat Pipe의 熱傳達 性能

김종일,김병철,한희석 조선대학교 동력자원연구소 1987 動力資源硏究所誌 Vol.9 No.2

This study was observed and analysed on the performance of a finned heatpipe used in the thermal energy storage system for the solar energy and heat recovery. For this purpose, a finned heat pipe was constructed with a groove screen wick, copper-water, 38㎜ in diameter and 500㎜ long. As the performance of a finned heat pipe depends upon operating temperature, tilt angle and fill charge, the axial and circumferential temperature of a finned heat pipe was measured and its performance was analysed. The maximum temperature difference, was largely influenced by fill charge, which decreased with increasing tilt angle when input was amall but not effected by tilt angle when input was large. The optimum fill charge was found to be 0.5, the dimensionless evaporator volume.

Microsporum gypseum 감염 1례

김성권,시차자,김의종,석종성 대한임상병리사협회 1993 대한임상병리사회지 Vol.25 No.1

기관지 결핵의 치료 중 발생한 다발성 기관지-늑막루 1예

김인숙,용석중,진춘조,신표진,정낙영,강소은,박학천,김정주,리원연,신계철 연세대학교 원주의과대학 2000 원주의대논문집 Vol.13 No.1

염모제 도포방법에 따른 인체 적혈구의 산화스트레스 비교

김영철,심미자,권정숙 한국환경독성학회 2004 환경독성보건학회지 Vol.19 No.2

To ascertain the effects of hair dyeing application on oxidative stress in human, a mixture of permanent black colored hair dye with the same amount of oxidant containing 6% hydrogen peroxide was used. A hair dyeing with contacting the scalp(conventional dyeing) and a hair dyeing with 3 to 4mm away from the scalp(alternative dyeing) were applied to each 15 young healthy women. Blood was taken from the brachial vein at two sampling times, just before and 6 hours after the hair dyeing, and antioxidant enzyme activities and antioxidant contents were measured in red blood cells. After increased, malondialdehyde(MDA) contents for conventional dyeing group was shown to a tendence for more increased than alternative dyeing group. After dyeing, reduced glutathione(GSH) contents for conventional dyeing group was shown to a tendence of more decreased than alternative dyeing group. After dyeing, superoxide dismutase(SOD) and catalase(CAT) activities were significantly decreased in conventional dyeing group(p<0.01), however, SOD and CAT activities were not significantly decreased in alternative dyeing group. After dyeing, there was no significant decrease in glutathione peroxidase(GPX) activity both for conventional dyeing group and alternative dyeing group. Therefore, after dyeing, the degree of oxidative stress in red blood cells for alternative dyeing group was appeared to be lower than conventional dyeing group.

Guinea pig의 腹腔動脈과 前腸間膜動脈에 관하여

金鍾涉,朴重錫,曺台純 慶尙大學校 1980 論文集 Vol.19 No.1

In order to investigate the variation in the pattern of origin of the celiac and the cranial mesenteric arteries, forty-four specimens (guinea pig) anesthetized by ethyl ether were heparinized and exsanguinated. Neoprene latex solution was injected into common carotid artery of thirty-two specimens for gross dissection. Twelve specimens angiography were prepared by injecting fifty per cent of barium sulfate solution into exsanguinated animals and then radiographed on a soft X-ray apparatus (Shimadzu Waltes 60). 1. The celiac artery and the cranial mesenteric artery were observed to be arosed mostly from a common trunk of the abdominal aorta, the celiac-cranial mesenteric trunk(68.2%), but in three animals from thirty specimens an anastomotic branch was examined between the abdominal aorta and the celiac artery(6.8%). 2. The celiac artery and the cranial mesenteric artery were branched from separated origin of the abdominal aorta(31.8%), and an anastomotic branch was examined between the celiac artery and the celiac-cranial mesenteric trunk(6.8%) in three animals from thirty specimens. 3. the hepatic artery was arosed from three different origin such as celiac artery branched from celiac-cranial mesenteric trunk(45.4%), celiac-cranial mesenteric trunk(22.2%) and the celiac artery branched from the abdominal aorta(31.8%).

鹽分의 過量攝取가 白鼠 腎臟에 미치는 影響에 對한 電子 顯微鏡的 硏究

김원석,설종구 충남대학교 의과대학 지역사회의학연구소 1990 충남의대잡지 Vol.17 No.1

In Korea, hypertension is the most common cause of death, however, it's pathogenesis is still unknown. There's a well-known hypothesis that essential hypertension is a disorder of accluturated peoples and is caused specifically by the acquired habit of eating salt. The study is made to know the ultrastructural change of rat kidney by salt only. Three different concentrations of salt(0.4%, 4.0%, and 8.0% of diet) were fed for 20 weeks. The results were as follows: 1. There was no specific change in control and low salt(0.4%) diet group. 2. In middle range salt(4.0%)diet group, widening of the glomerular capillary endothelial junction, focal adhesion of foot processes of podocytes, a few myeline formation, and focal irregularity of the capillary basement membrane were observed from 6th week, and the changes were more severe in long-feeding groups. The small arteries were showing marked hypertrophy of the smooth muscle cells with degeneration of the internal elastic lamina. However, the changes were somewhat different between animals. 3. In high salt(8.0%) diet group, the similar change with the middle range salt diet group was noted, but it was more early developed and more severe for time. There was striking myelin formation of the capillary endothlial cells, degeneration of the proximal convoluted tubular cells, widening of the intercellular space of small arterial smooth media, and proliferation of the mesangial cells. These degrees of change were also variable among animals. In summary, the results obtained by present study indicate that high salt intake alone also brings about hyperplastic and degenerative change that is similar to changes of hypertension in rats kidney.