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소아에서 벨 마비의 발생빈도, 임상적 특징 및 예후에 대한 연구
원유종,문경희,이완수,금승운,유승택,오경재,이창우,Won, Yoo Jong,Moon, Kyung Hee,Lee, Wan Soo,Keum, Seung Woon,Yu, Seung Taek,Oh, Gyung Jae,Lee, Chang Woo 대한소아청소년과학회 2007 Clinical and Experimental Pediatrics (CEP) Vol.50 No.3
목 적 : 벨 마비(Bell's palsy)는 특별한 원인이나 외상없이 얼굴 근육의 움직임을 지배하는 제7번 뇌신경에 이상이 생겨 안면운동이 마비되는 질환으로, 70-80%는 수일 또는 수 주일에 걸쳐 완전히 회복되나 일부는 후유증을 남긴다. 우리나라에서 소아의 벨 마비의 임상적 고찰에 대한 보고서가 부족한 상황이다. 이에 본원에서는 소아에서 나타난 벨 마비의 임상 양상과 나이에 따른 예후를 알아보고자 본 연구를 시행하였다. 방 법 : 1998년 1월부터 2006년 7월까지 원광대학병원에 안면마비를 주소로 내원한 15세 이하의 소아 61명을 대상으로 남녀 비율, 좌우 비율, 계절별 발생빈도, 치료 기간, 나이에 따른 완치율 등을 후향 적으로 분석하였다. 결 과 : 총 61명 중 남아는 31명, 여아는 30명으로 차이는 없었으며 좌우 병변 부위의 비율은 1:1.44 로 우측이 우세하였다. 월별에 따른 발병 빈도는 3개월(12월, 1월, 2월)에 22(36.0%)명으로 다른 월보다 높은 발병률을 보였다. 스테로이드 치료에 따른 완치 정도 및 완전 회복기간에 있어 유의한 차이는 없었다. 하지만 6세 미만에서 6세 이상에 비하여 완전 회복 기간이 4주 미만인 경우가 유의하게 많았다. 결 론 : 본 연구에서 소아 벨 마비의 발병빈도는 겨울에 높았고 예후는 나이가 어릴수록 좋았다. Purpose : Bell's palsy is defined as an idiopathic facial nerve paralysis of sudden onset. In spite of intensive clinical and experimental investigation, there is still uncertainty in the incidence, etiology, and preferred mode of treatment in children. The objective of this study was to analyze clinical outcome and prognosis of children with Bell' palsy. Methods : We analyzed 61 cases of Bell's palsy diagnosed at the Department of Wonkwang University Hospital from January 1998 to July 2006. The inclusion criteria were any children with acute isolated unilateral lower motor neuron type of facial nerve palsy. The clinical findings and investigations were reviewed including age, sex, affected site, seasonal incidence and result of steroid treatment. Chi-square and Fisher's exact test was used to compare clinical outcome between duration of complete recovery and age. Results : There was no difference in incidence according to sex or age. Incidence was higher in summer and winter. There was no difference in complete recovery rate and duration between steroid treated group and control group. In the group of children younger than 6 years, duration of complete recovery was shorter than older children. Conclusion : We found increasing the incidence of Bell's palsy in summer and winter. Children younger than 6 years had shorter duration in complete recovery.
이명희(Lee, Myung-Hee),원유미(Won, Yu-Mi),이택균(Lee, Taek-Kyun),박효주(Park Hyo-Joo) 한국체육과학회 2017 한국체육과학회지 Vol.26 No.2
The purpose of this study is to present the value of preventive medicine and the direction and meaning of healthy life for modern-day people with a number of health issues through a literary review of physical activities as part of preventive medicine through the curing method stated in Donguibogam. Heo Jun said that the human body consists of three major components of Jeong, Gi and Shin, which serve as the elements of vital activities engaging in a mutually organic relationship. Apparently, cleansing one’s heart and eliminating vain greed is one of the most fundamental and the best ways to prevent illness from the perspective of today’s preventive medicine. That is, a proper understanding of the condition and status of our body and correct identification of various symptoms will be the best way to maintain health and to prevent diseases in a preventive manner. Once we understand our physical body properly, we will not use our body in a reckless manner, which leads to the phrase of ‘too much is as bad as too little’ from the recuperative perspective of Donguibogam. Therefore, Donguibogam still presents outstanding meanings and implications from the viewpoint of preventive medicine intended to prevent and cure frequent modern-day diseases. I hope that modern people inevitably engaging in irregular and precarious lifestyle will be able to live a healthier life through an ideal harmony of recuperative physical activities and regular and correct diet habits. Health is not given for free. It is required to sustain a steady practice in the right direction. The effort to back up this academically and to suggest the right direction will work in a complementary and harmonious manner in multidisciplinary approach, combining physical education with medicine.
환추 저형성, 환추후두골 유합증, 두개저 함입증의 복합 기형 - 증례보고 -
조원중,원유삼,이승민,양재영,최천식,주문배,Cho, Won Jung,Won, Yu Sam,Lee, Seung Min,Yang, Jae Young,Choi, Chun Sik,Ju, Mun Bae 대한신경외과학회 2000 Journal of Korean neurosurgical society Vol.29 No.3
The term 'craniovertebral junction' refers to the occipital bone that surrounds the foramen magnum and the atlas and the axis vertebrae. A wide variety of congenital, developmental, and acquired anomalies exist at the craniovertebral junction. The authors present a rare case of the congenital anomaly of the craniovertebral junction consisting of atlantal hypoplasia, atlantal assimilation, and basilar invagination in a 58-year-old male. An occiput-C2 arthrodesis was performed. The clinical and imaging features are described, and the embryology and etiology of this anomaly are discussed.
블록체인을 활용한 특별관리임산물 품질관리 시스템의 설계
유성현 ( Sunghyun Yu ),이재호 ( Jaeho Lee ),정지원 ( Jiwon Jeong ),원유재 ( Yoojae Won ) 한국정보처리학회 2020 한국정보처리학회 학술대회논문집 Vol.27 No.2
특별관리임산물의 관리ㆍ감독을 위하여 법률을 바탕으로 품질관리제도를 마련하고 있으며, 현재 문서를 통해 관리하고 제도적인 신뢰에 의존하는 방식에 머물러 있다. 이는 많은 비용을 발생시키며, 제도를 악용하는 사기 사례가 발생하고 있다. 본 연구에서는 문제점을 해결하기 위해 블록체인을 이용한 특별관리임산물 품질관리 시스템을 제안한다. 해당 시스템은 품질 관리를 위한 문서를 법률에 따른 양식에 따라 전자문서로 생성하고, 문서 정보를 분산장부에 저장하여 누구나 확인 할 수 있도록 한다. 전자 문서들은 기관의 데이터베이스에 보관하여 확인 할 수 있도록 하며, 분산장부의 문서 정보 등록 이력을 통해 품질관리 이력을 추적하고 검증할 수 있도록 한다.
구개편도 및 인두편도에서 혈관내피성 접착분자의 발현에 관한 연구
조진희,장한성,원유성,이수진,윤희로,서병도,Cho, Jin-Hee,Jang, Han-Sung,Won, Yu-Sung,Lee, Soo-Jin,Yoon, He-Ro,Suh, Byung-Do 대한기관식도과학회 1999 大韓氣管食道科學會誌 Vol.5 No.2
The palatine tonsils(tonsils) and pharyngeal tonsils(adenoids) are situated at the entrance of the respiratory and alimentary tracts and represent the first site of contact with a variety of microorganisms and other antigens present in food and inhaled air. They are known as lymphoid organs carrying out the function of cellular and humoral immunity, and so they form a local protective barrier. And the expression of the vascular endothelial adhesion molecules is known to play an important role for the inflammatory reaction in tonsils and adenoids as well as in other inflammatory tissues, by binding with the receptors on the surface of leukocytes. But although several scientific hypotheses on the role of these lympoid tissues have been suggested, their complete functions have remained unknown. The purpose of this study is to present an basic data of the knowledge on the immunologic physiology of the tonsils and adenoids and their role as active immunologic organs that reinforce the mucosal immunity of the entire upper aerodigestive tract. We examined 16 human tonsils and adenoids and the expression of three endothelial adhesion molecules, vascular endothelial adhesion molecule-1(VCAM-1), intracellular adhesion molecule-1(ICAM-1), and E-selection, in tissue sections using immunohistochemistry. We used the inferior turbinate mucosa obtained from 9 patients getting septal surgery as a control group. The expressions of vascular endothelial adhesion molecule-1(VCAM-1) and intracellular adhesion molecule-1 (ICAM-1) were significantly higher in the tonsils and adenoids. But respectively, there were no significant differences between the tonsils and adenoids. The expression of E-selection was significant higher in the tonsils, but not in the adenoids. We observed that tonsils and adenoids showed significantly higher expressions of vascular endothelial adhesion molecule-1(VCAM-1), intracellular adhesion molecule-1(ICAM-1), and E-selection (in the case of E-selection, only in the tonsils). We propose that these adhesion molecules play an important role for the immunologic reaction by the transendothelial migration of lymphocytes and binding with the receptors on the surface of leukocytes.