각막 간질내 공기 주입과 평형염액 주입이 간질세포 자멸사에 미치는 영향 비교

이민정,이현주,위원량,이진학,김미금,Min Joung Lee,M,D,Hyun Ju Lee,Won Ryang Wee,M,D,Jin Hak Lee,M,D,Mee Kum Kim,M,D 대한안과학회 2007 대한안과학회지 Vol.48 No.4

Purpose: To evaluate the effects of intrastromal air injection and intrastromal balanced salt solution (BSS) injection on corneal keratocyte apoptosis. Methods: Twelve right eyes of New Zealand White rabbits were divided into an air-injected group (n=6) and a hydro-injected group (n=6). Contralateral eyes served as a control. Air or Balanced salt solution (BSS?, Alcon, USA) was injected into the deep corneal stroma at the paracentral area to propagate into nearly the entire cornea. To reduce the intraocular pressure, anterior chamber paracentesis was performed. The animals were sacrificed 4 hours (n=6) and 24 hours (n=6) after surgery. Central cornea buttons were retrieved to stain with Hematoxylin & Eosin and TUNEL (Apoptag?, Chemicon). The mean number of apoptotic keratocytes was counted in 24.67±4.04 consecutive high power field (HPF). Results: The mean number of TUNEL-positive cells at 4 hours was 12.85±7.25/HPF and 0.25±0.44/HPF in air-injected and hydro-injected eyes, respectively. It was reduced to 6.25±4.02/HPF and 0.15±0.37/HPF in air-injected and hydro-injected eyes after 24 hours. The air-injected group showed significantly more TUNEL-positive cells compared with the hydro-injected or control group until 24 hours (p=0.001, p=0.001, Mann-Whitney U test). Conclusions: Intrastromal air injection induces significant apoptosis of keratocytes suggesting some damages in the peripheral cornea when used in deep lamellar keratoplasty.

112, 119 긴급신고 대응 지능화 기술 개발 동향

이민정,박현호,백명선,권은정,변성원,박영수,정의석,박혜숙,M.J. Lee,H.H. Park,M.S. Baek,E.J. Kwon,S.W. Byon,Y.S. Park,E.S. Jung,H.S. Park 한국전자통신연구원 2023 전자통신동향분석 Vol.38 No.3

Emergency numbers, such as 112 and 119, are used in many countries to connect people in need with emergency services such as police, fire, and medical assistance. We describe development directions of intelligent response technology for emergency calls. The development of this technology refers to enhancing the efficiency and effectiveness of response systems by using advanced methods such as artificial intelligence, machine learning, and big data analytics. We focus on a system that assists the receptionist of an emergency call. In the future, the recognition rate and decision-making accuracy of intelligent response technologies should be improved considering characteristics of public safety and emergency domain data. Although the current technology remains at the level of assisting a receptionist, a fully autonomous response technology is expected to emerge in the future.

다직종 암환자 교육·상담에 대한 설문 개발과 환자 만족도 조사

이민정,금민정,김재송,김수현,손은선,이상글,송수경,최혜진,Lee, Min Jeong,Geum, Min Jung,Kim, Jae Song,Kim, Soo Hyun,Son, Eun Sun,Lee, Sang Geul,Song, Su Kyung,Choi, Hye Jin 한국임상약학회 2018 한국임상약학회지 Vol.28 No.2

Background: Presently, a multidisciplinary team of doctors, pharmacists, nurses, and dietitians provides patient education to impart information on chemotherapy. However, studies on multidisciplinary education satisfaction are inadequate. In this study, we aimed to contribute to the improvement of quality of multidisciplinary education counseling for patients with cancer by developing a satisfaction questionnaire and analyzing the satisfaction survey. Methods: A questionnaire was developed by an expert group, and the responses were recorded using the 5-point Likert scale. After conducting a pre-test, factor analysis was performed to evaluate validity. The reliability of the questionnaire was measured by Cronbach's alpha coefficient. A satisfaction survey was conducted by self-administration method. Results: Based on the results of factor analysis, factors can be divided into two parts: "overall education" and "each team member's education" (total 14 questions). The construct validity and reliability of the questionnaire are sufficiently high. Fifty-one patients took the survey between January 2, 2018 and January 20, 2018. Twenty-six (51%) patients responded that they were "very satisfied" and 22 (43.1%) patients responded that they were "satisfied". Conclusion: By developing a questionnaire on multidisciplinary education counseling for patients with cancer, it is possible to perform evaluation and research of cancer patient education. This study will contribute to the management and improvement of quality of multidisciplinary education.

반응 온도에 따른 CoO/Co(OH)₂ 나노시트의 합성

이민정,윤가영,류경희,Minjeong Lee,Gayoung Yoon,Gyeong Hee Ryu 한국재료학회 2023 한국재료학회지 Vol.33 No.5

Transition metal oxides formed by a single or heterogeneous combination of transition metal ions and oxygen ions have various types of crystal structures, which can be classified as layered structures and non-layered structures. With non-layered structures, it is difficult to realize a two-dimensional structure using conventional synthesis methods. In this study, we report the synthesis of cobalt oxide into wafer-scale nanosheets using a surfactant-assisted method. A monolayer of ionized surfactant at the water-air interface acts as a flexible template for direct cobalt oxide crystallization below. The nanosheets synthesized on the water surface can be easily transferred to an arbitrary substrate. In addition, the synthesizing morphological and crystal structures of the nanosheets were analyzed according to the reaction temperatures. The electrochemical properties of the synthesized nanosheets were also measured at each temperature. The nanosheets synthesized at 70 ℃ exhibited higher catalytic properties for the oxygen evolution reaction than those synthesized at other temperatures. This work suggests the possibility of changing material performance by adjusting synthesis temperature when synthesizing 2D nanomaterials using a wide range of functional oxides, resulting in improved physical properties.

거짓비늘증후군에 동반된 단독 섬모체망막동맥폐쇄 1예

이민정,박영걸,안재균,Min Joung Lee,Yeoung Geol Park,Jae Kyoun Ahn 대한안과학회 2006 대한안과학회지 Vol.47 No.10

Purpose: To report a case of isolated cilioretinal artery occlusion associated with pseudoexfoliation syndrome. Methods: A 66-year-old female presented with acute vision loss of the right eye. Three months prior, she had been diagnosed as having pseudoexfoliation glaucoma of both eyes, and the intraocular pressure of both eyes had been well-controlled with topical medication. Results: The presenting visual acuity in her right eye was 20/100. Fundus examinations showed sectoral retinal whitening on superior macula. Fluorescein angiography revealed delayed filling of the cilioretinal artery, consistent with cilioretinal artery occlusion. No significant findings were identified by carotid doppler examination or echocardiography. After 8 weeks, retinal changes were completely resolved with improvement of her right vision to 20/25. Conclusions: Isolated cilioretinal artery occlusion may develop as an intraocular manifestation of pseudoexfoliation syndrome.

학술 6 - 산화적 스트레스 및 항산화제에 관하여(1)

이민정,Lee, Min-Jeong 대한수의사회 2012 대한수의사회지 Vol.48 No.4

만성비염 환아의 수면의 질과 성장에 관한 임상적 연구

이민정,장규태,한윤정,Lee, Min-Jeong,Chang, Gyu-Tae,Han, Yun-Jeong 대한한방소아과학회 2008 대한한방소아과학회지 Vol.22 No.2

Objectives : The study was designed to find out the relationships between rhinitis, quality of sleep, growth among children with chronic rhinitis. Methods : This research was performed in 50 children from November 2007 to May 2008. We measured height, weight, body mass index of those children and asked to answer to the questionnaires that consist of nasal symptoms, period of time with rhinitis, sleep symptoms, parent's height, present illness, and medical history. We also analyzed correlations with this factors obtained from questionnaires. Results : 1. In 50 subjects, there were significant correlations between nasal obstruction, the quality of sleep, and the between quality of sleep and growth. But, there were not significant correlations between nasal symptoms and growth. 2. In 24 preschool children, frequency of waking up during sleeping and the number of snorers were higher and quality of sleeping was worse than those in the children who were attending school. And there were significant correlations between quality of sleep and nasal obstruction. An average of RH-MPH(Recent Height-Mid-Parental Height) is $-7.74{\pm}36.51(%)$ which means they aren't as tall as MPH(Mid-Parental Height). 3. In 26 school children, there were significant correlations between symptoms and period of rhinitis, quality of sleep and growth. Conclusions : Children with chronic rhinitis have low quality of sleep and low growth. But more studies are needed.

과민성 방광을 동반한 쇼그렌 증후군 소양인 환자 치험 1례

이민정,박민영,황민우,Lee, Min-jung,Park, Minyoung,Hwang, Min-woo 사상체질의학회 2020 사상체질의학회지 Vol.32 No.3

Introduction This study aims to report a significant improvement of Sjögren's syndrome patient with irritable bladder, diagnosed as 'Soyangin chest-binding symptomatology' based on Sasang medicine. Methods The patient had treatment with 'Dojeokganggi-tang' and western medications. We evaluated the treatment outcome of Sjögren's syndrome symptoms by using a numerical score of 0 to 10, based on the patient's subjective discomfort of dry eye and dry mouth, and irritable bladder symptoms by recording the number of night urination every month. Results Sjögren's syndrome symptoms were significantly improved, and the number of night urination was decreased. After 41 weeks of treatment, the patient didn't have dry mouth any more and had only a little dry eye. The number of night urination was decreased from 3-4 times to once a night. Discussion The patient diagnosed with Sjögren's syndrome, treated with Dojeokganggi-tang and western medications for 41 weeks, showed a significant improvement in dry eye, dry mouth, and night urination compared to the first visit.

A Case of Cystitis with Bilateral Hydronephrosis Presenting with Gross Hematuria

이민정,곽병옥,송민경,정소정,김교순,Lee, Min Jung,Kwak, Byung Ok,Song, Min Kyung,Chung, Sochung,Kim, Kyo Sun Korean Society of Pediatric Nephrology 2012 Childhood kidney diseases Vol.16 No.2

평소 건강했던 아이들에서 육안적 혈뇨는 드물게 나타나며, 수신증과 동반된 경우 또한 드물다. 3세 남아가 육안적 혈뇨와 배뇨통을 주소로 내원하였다. 소변검사에서 농뇨, 혈뇨 보였으나 소변 배양 검사에서 균이 배양되지 않았으며, 혈액검사와 신체 검진상에서는 특이 소견 관찰되지 않았다. 초음파 검사상 양쪽 수신증과 함께 방광 벽이 두꺼워진 소견 보였다. 배뇨 요도 방광 조영술상 방광 요관 역류는 관찰되지 않았으나 방광 벽 비후가 심했으며, 방광 용적이 줄어들고 모양이 찌그러져있었다. 진단 후 ceftriaxone을 2주간 치료하였다. 항생제 치료 일주일 후 혈뇨 소실되어 초음파 검사를 다시 시행하였고 양쪽 수신증의 호전과 방광 용적 및 모양이 정상으로 호전됨을 관찰하였다. 환아의 배뇨통 증상도 호전되어 퇴원하였다. 외래 추적 관찰 중에 역류 검사 재 시행하였으며 정상 소견 보였다. 육안적 혈뇨 및 현미경적 혈뇨는 더 이상 관찰되지 않았다. 본 저자들은 육안적 혈뇨를 보인 소아에서 양측성 수신증을 동반한 방광염 1례를 경험하여 보고하는 바이다. Gross hematuria is uncommon, and rarely associated with hydronephrosis in healthy children. We describe a 3-year-old boy who complained of gross hematuria and dysuria. He was diagnosed as cystitis with bilateral hydronephrosis, and treated with antibiotics and conservative therapy. Our experience suggests that cystitis with hydronephrosis can occur in healthy children presenting with gross hematuria.

성조숙증(性早熟證)에 관한 연구의 최근 동향;최근 중의(中醫) 잡지를 중심으로

이민정,장규태,한윤정,Lee, Min-Jeong,Chang, Gyu-Tae,Han, Yun-Jeong 대한한방소아과학회 2008 대한한방소아과학회지 Vol.22 No.1

Objectives The aim of this study was to investigate the treatment of precocious puberty in current traditional Chinese medical journals. Methods To figure out diagnosis methods, treatment methods, treatment effects of oriental medicine about precious puberty, Chinese medical journals from China National Knowledge Infrastructure (CNKI) which was published from 1999 to 2007 were analyzed and precocious puberty was also been searched. Results 82 articles were selected. 1. Yin and purging Fire(滋陰瀉火) from traditional Chinese Medicine was usually used. 2. The herbs were almost used such as Rehmannia glutinosa(地黃), Anemarrhena asphodeloides (知母), Phellodendron amurense(黃柏), Thesium chinense(夏枯草), Paeonia suffruticosa Andrews(牧丹皮), Alisma canaliculatum(澤瀉), Testudinis Plastrum(龜板), Paeonia japonica(白芍藥), Bupleurum falcatum(柴胡), Genianae Scabrae Radix(龍膽草). 3. The total improvement rate was 72.50 to 100% Conclusions The oriental medical treatments for precocious puberty were presumed to be effective, but more studies are still needed.