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폐암환자 말초혈액의 자연살해세포 표현형(Natural Killer Cell Phenotypes)과 T임파구 아형 (T-Cell Subsets)의 의의
남재만,서지원,김남재,김주옥,김선영 충남대학교 의과대학 지역사회의학연구소 1989 충남의대잡지 Vol.16 No.2
The authors studied the NK cell phenotype and T cell subsets in 36 patients with bronchogenic carcinoma and 11 healthy controls. The results were summarized as follows. 1. The percentage of lymphocyte and total lymphocyte counts significantly decreased in cancer patients compared to normal control(p<0.05). 2. The OKT4^+(%) was significantly decreased in patients according to celltype (especially squamous cell cancer, adenocarcinoma and large cell carcinoma) and extended stage(stageⅢ) (p<0.05), but no change in limited stage(stage Ⅰ&Ⅱ). 3. The OKT8^+(%) and OKT4^+ ratio were not significantly changed in cancer patient. 4. According to cell type, there was no significant difference of NK cell phenotype between cancer patients and controls. 5. According to stage, there was no significant difference of NK cell phenotype between cancer patients and controls. 6. There was no significant difference of NK cell phenotype in cancer patients compared to normal controls. We concluded that NK cell phenotype had no significant difference between cancer patients and healthy controls. Further studies (including NK cell activity or other function tests of lymphocyte) are needed to analyze the roles of immunologic responses in patients with lung cancer.
급만성 호흡기감염증에 대한 Ciprofloxacin의 임상효과에 대한 연구
이경주,남재만,서지원,김선영 대한화학요법학회 1988 대한화학요법학회지 Vol.6 No.2
Ciprofloxacin is a new generation of DNA gyrase inhibitor and has a broad antibacterial spectrum that includes the majority of Enterobacteriaceae, p. aeroginosa, Hemophilus, and many gram positive cocci including methicillin-resistant S. aureus. An clinical trial was performed to evaluate the efficacy and safety of ciprofloxacin in 33 patients with respiratory tract infection. The treatment was successful in 100% in acute RTI, 85% in chronic RTI. Adverse reaction was observed in 2 patients which was GI disturbance and itching.
급· 만성 호흡기감영증에 대한 Ciprofloxacin의 임상효과에 대한 연구
이경주,남재만,서지원,김선영 中央醫學社 1988 中央醫學 Vol.53 No.12
Ciprofloxacin is a new generation of DNA gyrase inhibitor and has a broad antibaterial spectrum that includes the majority of Enterobacteriaceaea. P. aeruginosa, Hemoiphilus, and many gram positive cocci including methicillin-resistant S. aureus. An clinical trial was performed to evaluate the efficacy & safety of ciprofloxacin in 33 patients with respiratory tract infection. The treatment was successful in 100 % in acute RTI, 85 % in chronic RTL Adverse reaction was observed in 2 patients which was GI disturbance and itching.
BENZALKONIUM 이온 도입 치료를 이용한 조갑진균증의 치료에 관한 연구
박래준,남재만,서현규 대한물리치료학회 2000 대한물리치료학회지 Vol.12 No.1
The purpose of this study was determine the effects of the benzalkonium iontophoresis on onychomycosis (hand). The participants consisted of 10 patients. This study was observed the change of normal nail length and infected nail square three time ; pre-treatment, after 6 treatment and after 10-treatment The results of this study were as follows. 1. The length increase of normal nail revealed significant statistically after 10 times treatment(p$lt;0.05). 2. The square diminish of infected nail revealed significant statistically after 10 times treatment(p$lt;0.05). 3. Infected nail thickening and spilt sloped and nail colors recovered after 10 times treatment. 4. The nail with iontophoresis recovered more quickly than the with nail lacquer in the same patients.
이영,송규상,남재만,전은석,김선영,이복희,성인환,이경주 대한내과학회 1988 대한내과학회지 Vol.35 No.5
A case of a 58-year-old man with malignant fibrous histiocytoma (NFH) of the right ventricle is presented and the 9 previous reports of this rare cardiac tumor are reviewed. The chest PA showed cardiomegaly and small nodular densities in the right lower lung field. There were multiple perfusion defects in the right lung an perfusion lung scan. On echocardiogram, dilated right atrium and ventricle, mass on RVOT, tricuspid regurgitation and moderate pericardial effusion were noted. No lesions were noted in the liver, kidney, spleen, or pancreas on ultrasound. The microscopic view of the tumor showed a storiform pattern of fibroblasts, histiocytes, multinuclear giant cells and inflammatory cells. The patient died during open heart surgery for tumor resection.