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피부근염에서 동시에 발생된 거대세포바이러스 폐렴과 망막염
윤장욱 ( Jang Uk Yoon ),윤호성 ( Ho Sung Yoon ),곽승기 ( Seung Ki Kwok ),고혁재 ( Hyek Jae Koh ),김호연 ( Ho Youn Kim ),박성환 ( Sung Hwan Park ) 대한류마티스학회 2009 대한류마티스학회지 Vol.16 No.3
Cytomegalovirus (CMV) infection commonly affects patients who are in an immunocompromised state, such as acquired immune deficiency syndrome (AIDS) and during organ transplantation. Although cytomegalovirus infection does not occur frequently, it is a major cause of morbidity and mortality in patients suffering with connective tissue diseases, including dermatomyositis. Cytomegalovirus pneumonitis and retinitis has been rarely reported in patients with dermatomyositis. We report here on an usual case involving the simultaneous occurrence of cytomegalovirus pneumonitis and retinitis in a 39-year-old female with dermatomyositis, and this woman had been treated with steroids and immunosuppressive agents for the previous 5 months.
저비중 지단백 콜레스테를 농도의 측정에 있어서 Friedwald 공식과 면역분리법을 이용한 직접측정의 비교
김규원 ( Gyu Won Kim ),조병동 ( Byung Dong Cho ),이형석 ( Hyung Seok Lee ),정승현 ( Seung Hyun Jung ),오길찬 ( Kil Chan Oh ),윤장욱 ( Jang Uk Yoon ),백승훈 ( Seung Hun Baek ),유규형 ( Kyu Hyung Ryu ),임종윤 ( Chong Yun Rhim ),조 대한내과학회 2003 대한내과학회지 Vol.64 No.1
배경 : 심혈관계 질환의 위험인자로 알려진 고지혈증에서 저비중 지단백 콜레스테롤을 측정할 때 중성지방치가 400mg/dL 이상인 사람에서는 저비중 지단백 콜레스테롤의 측정에 Friedwald의 공식을 적용할 수 없으므로 면역분리법으로 직접 측정한 저비중 지단백 콜레스테롤과 Friedwald의 공식에 의해 구한 저비중 지단백 콜레스테롤치와 비교하여 직, 간접측정방법간의 차이를 확인하여, 향후 고지혈증 치료시 저비중 지단백 콜레스테롤의 수치를 더욱 정확하고 Background : In 2001, the third report the National Cholesterol Education Program (NCEP) has concluded that LDL cholesterol levels should be a major goal for preventing coronary artery disease and atherosclerotic events. Those in the higher risk groups sh
윤장욱,박상훈,김은정,홍지현,이형석,오길찬,박철희,한태호,이동근,김종혁,박혜림,박충기 대한간학회 2003 Clinical and Molecular Hepatology(대한간학회지) Vol.9 No.3
Autoimmune hepatitis (AIH) is a chronic necroinflammatory liver disease of unknown cause associated with circulating autoantibodies and high serum globulin level. Systemic lupus erythematosus (SLE) is a disease of unknown etiology in which tissues and cells are damaged by pathogenic autoantibodies and immune complex, affecting multiple organs including the liver, kidney, and CNS. The difference between the hepatic involvement of SLE and autoimmune hepatitis has not been clearly defined in the past due to similarities in clinical and biochemical features. A scoring system for the diagnosis of AIH has been established, and AIH and SLE associated hepatitis have been defined as two different entities, although both have the same autoimmune features such as polyarthralgia, hypergammaglobulinemia and circulating autoantibodies. AIH has been considered to occur infrequently in SLE. We report two cases of AIH which simultaneously satisfied the criteria of SLE.(Korean J Hepatol 2003;9:231-235)
윤장욱,정영옥 대한내과학회 2003 대한내과학회지 Vol.64 No.2
폐암이 소장으로 전이된 경우 임상 증상이 뚜렷하지 않기 때문에 조기에 발견하기가 어려우며, 또한 복통, 오심, 구토 등의 증상이 있을 때는 장중첩증이나 장폐쇄로 인한 복막염이 함께 있는 경우가 많기 때문에 예후가 극히 불량하다. 소장 전이로 외과적 처치를 한 후 평균 생존율은 12주 이하였으며, 16주 이상 생존한 경우는 한 예를 제외하고는 없었다. 본 저자들은 47세 남자 환자에서 비소세포폐암의 공장 전이로 인한 장중첩증이 진단되어, 공장 부분 절개술 및 문합술 후 보존적 항암요법을 시행하여 폐암의 소장 전이로 진단된 후 30주 생존한 예를 경험하여 보고하는 바이다. Metastasis to small bowel from non-small cell lung cancer is known to be very rare. Here we report a case of intussusception induced by jejunal metastasis of non-small cell lung cancer. A 47-year old man was admitted to hospital complaining cough and sputum for 3 months. He was diagnosed as squamous cell lung cancer by percutaneous needle biopsy of lung mass detected by chest X-ray and CT. Multiple brain metastatic lesions were detected by brain CT on admission. systemic chemotherapy with whole brain irradiation was performed. After three cycles of chemotherapy, he was admitted with sudden-onset abdominal pain, nausea and vomiting. Jejunal intussusception was the diagnosis by abdominal CT and histologic examination of resected jejunum showed it was induced by metastatic mass from the primary lung cancer. (Korean J Med 64:235-239, 2003)
Emphysematous Cystitis with Bladder Rupture by Candida albicans
Kim, Ki-Seong,Moon, Sun You,Yoon, Jang Uk,Lee, Seung Soon,Cho, Jin Seon,Chung, Doo Ryeon 대한감염학회 2005 감염과 화학요법 Vol.37 No.2
공기증방광염(emphysematous cystitis)은 주로 당뇨병이나 신경탓방광 환자에서 발생하는 드문 감염질환으로서 치명률이 매우 높다. 이의 원인 미생물은 Escherichia coli, Klebsiella와 같은 세균이 가장 흔하며 칸디다에 의한 증례는 아주 드물어 현재까지 몇 증례만 보고되어 있을 뿐치다. 이 중에서도 방광 파열이 동반된 증례는 non-albicans Candida 종에 의한 증례가 2예 보고되었을 뿐이다. 저자 등은 Candida albicans에 의한 공기증방광염이면서 자발적 방광 파열로 초기 발현된 증례를 경험하여 이를 문헌 고찰과 함께 최초로 보고하는 바이다. Emphysematous cystitis is an uncommon life-threatening disease, which often occurs in patients with diabetes mellitus or neurogenic bladder. Bacterial etiologies are common, while cases by Candida species have been very rarely reported. To date, only six cases of Candida albicans related emphysematous cystitis have been reported; two cases resulted in bladder repture and the causative organisms were non-albicans Candida species. We report the first case of emphysematous cystitis caused by Candida albicans accompanying a spontaneous bladder rupture with the review of literatures.