시신경 유두부 주위에 국한된 양안 망막 포도송이 혈관종 1예

우영준,이윤하,윤이나.Young Jun Woo. MD. Yoon Ha Lee. MD. Ie Na Yoon. MD 대한안과학회 2011 대한안과학회지 Vol.52 No.11

Purpose: The authors of the present case report observed a bilateral retinal racemose hemangioma which was located within the peripapillary area. Case summary: A 17-year-old man presented with floaters in both eyes. Fundus revealed tortuous and anastomosed retinal vasculature around the optic disc. In addition, fluorescein angiography showed a non-leaking retinal arteriovenous anastomosis. Seven years after the initial visit, vitreous hemorrhage occurred in the patient’s left eye, and then 1 year later, subretinal hemorrhage was found in his left eye. Conclusions: Because retinal racemose hemangioma can accompany vitreous hemorrhage and subretinal hemorrhage regardless of size, a routine periodic ophthalmic examination is recommended. J Korean Ophthalmol Soc 2011;52(11):1381-1384

Orbital Lymphangioma: Characteristics and Treatment Outcomes of 12 Cases

우영준,김창염,Bradford Sgrignoli,윤진숙 대한안과학회 2017 Korean Journal of Ophthalmology Vol.31 No.3

Purpose: To report the patient characteristics and treatment outcomes in 12 cases of orbital lymphangioma. Methods: In this study, orbital lymphangioma was diagnosed based on clinical, radiologic (computed tomography,magnetic resonance imaging), and histologic findings when possible. Patients whose vision was notcompromised by orbital lymphangioma, or that did not have increased intraocular pressure (IOP), receivedoral corticosteroids. Orbital lymphangioma that affected vision or increased IOP was treated by surgery, whichincluded aspiration of blood or partial resection with or without injection of a sclerosant. Results: Four patients without compromised vision responded well to oral corticosteroids. Eight patients withcompromised vision underwent some form of surgery. Bleeding recurred in three patients after aspiration ofblood and in two after partial resection and intralesional injection of a sclerosant. Overall, five patients weretreated successfully by aspiration of blood, intralesional injection of a sclerosant, and application of continuousnegative pressure by appropriate drainage. Partial resection was successful in two patients with organized hematoma. Conclusions: Orbital lymphangioma that does not compromise vision can be treated medically using oral corticosteroids. Patients with threatened vision or elevated IOP due to acute hemorrhage should be treated by aspirationof blood, intralesional injection of a sclerosant, and application of continuous negative pressure. Partialresection may be effective only in patients with organized hematoma.

스트레스가 안압 및 눈물분비에 미치는 영향

우영준,김지업,나상훈,이종혁,Young Jun Woo,Ji Eob Kim,Sang Hoon Rah,Jong Hyuck Lee 대한안과학회 2012 대한안과학회지 Vol.53 No.9

Purpose: To evaluate the effects of psychosocial stress on intraocular pressure and lacrimal secretion. Methods: Twenty normal adult volunteers (40 eyes) who had no history of systemic or ocular disease such as dry eye syndrome or glaucoma were recruited from clinical research participants. Heart rate, intraocular pressure and lacrimal secretion were measured after the Trier Social Stress Test (TSST) which induces psychosocial stress. The same measurements were taken 1 week later and the recorded measurements were considered as the control group. Results: Heart rate was elevated significantly after the TSST, indicating psychosocial stress was induced by the TSST. Compared to stress resolution status, intraocular pressure and lacrimal secretion were increased after the TSST (p = 0.027, p = 0.011). Elevation of intraocular pressure and lacrimal secretion was statistically significant in males (p = 0.031, p = 0.007), but not significant in females (p = 0.336, p = 0.554). Conclusions: Psychosocial stress can increase intraocular pressure and lacrimal secretion. J Korean Ophthalmol Soc 2012;53(9):1304-1310

한눈사시 환자에서 시력회복 후 사시각의 변화

우영준,이종혁,라상훈 대한안과학회 2009 대한안과학회지 Vol.50 No.12

Purpose: Anisometropia can lead to monocular deviation if the refractive error is not corrected. Therefore, the authors evaluated the change in angle deviation after visual acuity improvement by refractive correction in monocular deviated patients with anisometropia. Methods: Changes in angle deviation were collated retrospectively for 9 patients with anisometric monocular deviation, 7 with monocular exotropia and 2 with monocular esotropia, according to medical records. The patients were admitted for strabismus surgery performed using cataract extraction or clear lens extraction (8 patients) or were treated nonsurgically using contact lenses for visual acuity recovery (1 patient). Results: Prior to corrective measures, patients with exotropia had, on average, exodeviation of 40.43 PD, and those with esotropia had, on average, esodeviation of 27.50 PD. After corrective measures were taken, all 7 exotropia patients had decreased angle deviation, and, upon final evaluation, exodeviation had decreased to 21.71 PD, on average. In two exotropia patients, measures taken to correct refractive error shifted the exotropia to exophoria. There was no change in angle deviation after Corrective measures in 2 esotropia patients. Conclusions: In cases of exotropia caused by decreased visual acuity, correction of the visual acuity should be performed first if the correction is possible. After the recovery of visual acuity, a significant decrease in angle deviation occurs. 목적: 굴절부등에서 시력교정을 충분히 시행하지 않는 경우 한눈사시가 발생할 수 있다. 저자들은 굴절부등을 동반한 한눈사시 환자에 서 시력회복 후 사시양상 및 사시각의 변화에 대해서 알아보고자 하였다. 대상과 방법: 1997년부터 2007년까지 사시수술을 위하여 본원에 내원하였던 환자 중 시력회복이 가능하였던 한눈 외사시 7명, 한눈 내사시 2명에서 투명 수정체 적출술을 포함한 백내장 수술 또는 콘택트렌즈를 통한 시력회복 후 사시형태 및 사시각의 변화를 후향적 으로 조사하였다. 결과: 8명에서는 백내장 수술, 1명에서는 콘택트렌즈를 이용하여 시력을 교정하였다. 교정 전 외사시를 보인 7명의 평균 외사시각은 40.43PD이었고 내사시 2명의 평균 내사시각은 27.50PD이었다. 교정 후 외사시 환자 7명 모두 점차 사시각이 줄어들어 최종 관찰시 평균 외사시각 21.71PD 으로 감소하였고, 2명은 사위로 변화하였다. 내사시 환자 2명에서는 시력회복 후에도 사시각의 변화를 관찰 할 수 없었다. 결론: 한눈시력의 감퇴로 생긴 외사시의 경우, 시력회복 후 사시각이 감소 할 수 있으므로, 시력회복이 가능하다면 사시 교정술 보다 시력 교정이 먼저 선행 되어야 하겠다.

신경망을 이용한 영상압축

박동철,우영준 明知大學校 産業技術硏究所 1999 産業技術硏究所論文集 Vol.18 No.-

A new image compression algorithm based on an unsupervised competitive neural network to prevent the edge degradation is proposed in this paper. The proposed unsupervised competitive neural network, called Weighted Centroid Neural Network(WCNN), utilizes the characteristics of image blocks from edge areas. The M/RVQ(Mean/Residual VQ) scheme is utilized in this proposed approach as the frame work of the proposed algorithm. A novel measure for calculating edge strength is devised by using the reside of an image block data from M/R scheme in this paper. The edge strength of an image block data is then utilized as a tool to allocate the proper codevectors in the proposed WCNN. The WCNN successfully allocates more codevectors to the image block data from edge area while it allocates less codevectors to the image block data from shade or non-edge area when compared to conventional neural network based VQ algorithm. As a result, a simple application of WCNN to image compression problem gives improved edge characteristics in reproduced images over conventional neural network based VQ algorithm such as SOM, M/RVQ, and modified SOM..

전기와 미녹시딜 복합 자극을 통한 인간 모유두세포의 성장 촉진 상승효과

우영준 ( Young Jun Woo ),정관호 ( Kwan Ho Jeong ),김정은 ( Jung Eun Kim ),강훈 ( Hoon Kang ) 대한피부과학회 2016 大韓皮膚科學會誌 Vol.54 No.5

Background: Previous published clinical studies have demonstrated the positive effects of electrical stimulation (ES) on hair growth. Minoxidil (MXD) enhances hair growth by prolonging the anagen phase of hair follicles. MXD is used to promote hair growth in androgenetic alopecia. Objective: To investigate the combined effect of ES and MXD on cultured human dermal papilla cells (hDPCs). Methods: hDPCs were electrically stimulated with different parameter settings of alternating current. Electrically stimulated hDPCs were incubated in an MXD medium, after which cell proliferation was measured using an MTT assay. Ki-67 and β-catenin expressions were measured by immunofluorescence assay. In addition, Wnt/β-catenin pathway-related gene expressions were measured by real time-PCR, and phosphorylated ERK and AKT protein levels were measured by western blot assay. Results: The combination of 8 V-1 MHz ES and MXD treatment promoted hDPC proliferation effectively, compared with that in the control, ES alone, or MXD alone treatment groups. The immunofluorescence assay showed that the expression of Ki-67 and β-catenin significantly increased in the combined treatment group. Most of the Wnt/β-catenin pathway-related gene expressions increased more with combined treatment than with the control, ES alone, or MXD alone treatments. However, there were no significant differences in the expression levels of phosphorylated ERK and AKT among the treatment groups. Conclusion: ES combined with MXD treatment had a synergistic effect on the proliferation of hDPCs. This might be through the synergistic activation of the Wnt/β-catenin pathway. (Korean J Dermatol 2016;54(5):341∼349)

미녹시딜 도포로 호전을 보인 청소년기 여아에서 발생한 안드로겐 탈모증 1예

우영준 ( Young Jun Woo ),김윤섭 ( Yoon Seob Kim ),김정은 ( Jung Eun Kim ),강훈 ( Hoon Kang ) 대한피부과학회 2017 大韓皮膚科學會誌 Vol.55 No.1

Androgenetic alopecia (AGA) is a common form of hair loss that usually occurs in the third or fourth decades of life in men, with later onset in women. AGA does rarely occur, however, in the pediatric population. Adolescent AGA is pattern hair loss occurring in boys and girls between 12 and 18 years of age. We herein report the case of a 16-year-old girl with a 5-year history of diffuse hair loss on the crown. Her father had a history of AGA, and the hair pull test was negative. Sex hormone levels and thyroid function test were within the normal range. Phototrichogram analysis revealed diffuse hair thinning over the frontal and vertex areas, and the percentage of vellus hair was higher on the vertex than the occiput. We diagnosed the patient with adolescent AGA. She was prescribed 3% topical minoxidil, and improvement was visible on the clinical photograph and phototrichogram after 2 years of treatment. (Korean J Dermatol 2017;55(1):52∼55)

신경망에 의한 테두리를 보존하는 영상압축

박동철,우영준 한국통신학회 1999 韓國通信學會論文誌 Vol.24 No.10

무지도 경쟁학습을 이용하여 압축된 영상의 복원 후에 나타나는 테두리부분의 손상을 최소화하기 위한 영상압축 방법이 제안되었다. 제안된 영상압축방법은 영상데이터에서 테두리부분에 해당하는 데이터의 기하학적인 특징을 이용하는데, 영상데이터의 통계학적인 특성을 함께 이용하여 기존의 Centroid Neural Network을 일반화시키는 무지도 경쟁학습에 의하여 자동적으로 더욱 많은 code vector를 테두리부분에 배정함으로서 압축된 영상의 복원 후에 나타나는 테두리부분의 손상을 초소화하게 한다. 실험 결과, 기존의 SOM, M-SOM, M/R-CNN등과 비교하여 제안된 방법에 의해 압축된 영상의 복원된 테두리 부분에서 PSNR이 약 2dbv정도 향상된 결과를 보여줄 수 있었다. A new image compression method to preserve edge characteristics in reconstructed images using an unsupervised learning neural is proposed in this paper. By the unsupervised competitive learning which generalizes previously proposed Centroid Neural Network(CNN) algorithm with the geometric characteristics of edge area and statistical characteristics of image data, more codevectors are allocated in the edge areas to provide the more accurate edges in reconstructed image. Experimental results show that the proposed method gives improved edge in reconstructed images when compared with SOM, Modified SOM and M/R-CNN.

Surgical Outcomes of Porcine Acellular Dermis Graft in Anophthalmic Socket: Comparison with Oral Mucosa Graft

Livia Teo,우영준,김동규,김창염,윤진숙 대한안과학회 2017 Korean Journal of Ophthalmology Vol.31 No.1

Purpose: We describe our experience with the Permacol graft in anophthalmic socket reconstruction, and compareit to the autologous buccal mucosal graft, emphasizing the postoperative vascularization and contractionof each graft. Methods: This was a retrospective comparative study. We measured the time necessary for the graft surface tobe completely vascularized, as well as the fornix depth of the conjunctival sac in anophthalmic patients. Results: Ten patients underwent Permacol graft reconstruction, with 44 undergoing buccal mucosal graft reconstruction. Seven eyelids (70%) in the Permacol group had a good outcome, with improvement in lower eyelidposition and prosthesis retention. Nine out of 10 eyelids (90%) in this group showed complete vascularizationof the graft at 2.6 ± 1.9 months postoperatively, while the grafted buccal mucosa was fully vascularized at 1.1± 0.3 months postoperatively (p < 0.01). Postoperative fornix depth in the Permacol group was 9.1 ± 2.2 mm,compared to 14.9 ± 4.5 mm in the buccal mucosal graft group (p < 0.01). Mean increases in fornix depth were33.1% and 67.9% of the mean vertical length of the implanted graft. Conclusions: The Permacol graft can be useful as spacer graft material in anophthalmic socket patients. Ittakes longer to vascularize, and undergoes greater graft shrinkage with time, compared to the buccal mucosalgraft.

산불 피해목으로 만든 바이오차 시용이 산불 토양특성에 미치는 영향

김성호(Sungho Kim),우영준(Young Jun Woo),정대영(Dae Young Jeong),육진수(Jin Soo Yuk),김병철(Byeong Cheol Kim),이창훈(Chang Hoon Lee) 한국토양비료학회 2023 한국토양비료학회 학술발표회 초록집 Vol.2023 No.10