자기결정성 정도에 따른 동기유형의 분류

김아영(Ah Young Kim),오순애(Soon Ae Oh) 한국교육심리학회 2001 敎育心理硏究 Vol.15 No.4

표고버섯이 고지방식이로 유도한 비만 흰쥐에 미치는 항비만 효과

이미라(Mi Ra Lee),오득실(Deuk Sil Oh),위안진(An Jin Wee),윤병선(Byung Sun Yun),장순애(Soon Ae Jang),성창근(Chang Keun Sung) 한국식품영양과학회 2014 한국식품영양과학회지 Vol.43 No.2

본 연구는 표고버섯 물추출물의 항비만 효과를 알아보기 위하여 6주령의 수컷 C57BL/6 마우스를 이용하여 고지방식이와 함께 표고버섯 물추출 분말을 1%, 3%, 5% 수준으로 첨가하여 12주간 공급하였다. 고지방 식이섭취는 체중, 혈청지질 농도 및 지방조직 무게를 증가시켰다. 표고버섯 물추출물 섭취는 고지방식이로 증가된 혈청 총콜레스테롤, 중성지방, LDL-콜레스테롤 농도를 현저히 감소시켜 대조군보다 더 낮은 값을 나타냈다. 또한 5% 표고버섯 물추출물 첨가군은 고지방 식이군보다 체중 및 피하지방량이 현저히 감소하였다. 변배설량은 3%와 5% 표고버섯 물추출물 첨가군에서 고지방 식이군보다 현저히 증가하였다. 표고버섯 물추출물 섭취는 고지방식이로 인해 증가된 간조직의 지방축적과 지질과산화물 형성을 억제하였으며, 특히 5% 표고버섯 물추출물 섭취군에서 지질과산화물 형성이 유의적으로 감소되었고 총 항산화 활성도 유의적으로 가장 높게 나타났다. 고지방식이군은 간조직의 조직염색에서 지방간이 심하게 진행된 것이 발견되었고, 표고버섯 물추출물 섭취군은 지방세포에 지방이 침투하지 않은 간지방증 소견을 보였다. 위의 결과를 통하여 볼 때 표고버섯은 체중 및 체지방 감소, 그리고 혈청지방 농도 개선에 효과가 있어 비만관리에 도움을 주는 것으로 사료된다. The aim of this study was to investigate the anti-obesity effects of Lentinus edodes water extract powder (LEP) in mice fed a high fat diet (HF, 45% kcal fat). Mice were administrated a HF diet supplemented with 1%, 3%, or 5% LEP for 12 weeks. Consumption of HF diet caused increases in body weight, serum lipid profiles, and adipose tissue weights. Serum TC and TG levels in the LEP-supplemented groups were lower than those in the NC group. Supplementation with 5% LEP significantly suppressed body weight gain and reduced the weight of subcutaneous adipose tissue compared to the HF group. HF diet ingestion resulted in higher lipid content and increased lipid peroxidation in the liver. However, LEP supplementation inhibited accumulation of hepatic lipids induced by HF diet, considerably decreased MDA levels, and elevated total antioxidant activity in the livers of mice in the 5% LEP group. Histopathological analysis indicated that the livers of mice fed HF diet developed hepatic steatosis, whereas LEP-treated groups showed small fat droplets. These results suggest that long-term supplementation with LEP may also have an ameliorating effect on HF-induced obesity.

극소 저체중 출생아의 발생빈도 및 근 치료 성적

강순애,오연균 圓光大學校 醫科學硏究所 2008 圓光醫科學 Vol.23 No.2

목적: 신생아 집중치료의 발달로 국내 3 차 대형병원에서는 극소 저체중 출생아 뿐만 아니라 초극소 저체중 출생아에서도 괄목 할만한 생존율의 향상을 보이고 있다. 따라서 본원에서의 극소 저체중 출생아의 빈도, 생존율, 이환율 등 집중치료 결과를 비교 분석 해보고 더욱 향상된 치료가 될 수 있도록 도움을 얻고자 본 연구를 시행하였다. 방법: 2000년 1월부터 2006년 12월까지 만 7년까지 원광대학교 병원 신생아 집중치료실에 입원한 1,500g 미만의 극소 저출생 체중아 205명을 대상으로 의무기록을 조사하여 후향적으로 결과를 분석하였다. 결과: 극소 저출생 체중아의 발생빈도는 4.2%였다. 생존율은 75.0%로 타병원의 80% 이상의 높은 생존율에 비해 다소 낮았다. 1,250g 이상은 92.6%로 타병원과 비슷한 높은 생존율을 보였으나 750g 미만은 18.2%로 낮은 생존율을 보였다. 29주 이상은 80% 이상의 높은 생존율을 보였으나 25-26주는 38.9%로 낮았으며 24주 이하는 한명도 생존하지 못하였다. 주요 합병증은 호흡곤란 증후군이 75.0%로 가장 많았으며, 뇌출혈 31.7%, 동맥관 개존증 29.3%, 미숙아 망막증 28.8%, 패혈증 27.3%, 만성폐질환 23.4%의 순이었다. 사망 시기는 3일 이내가 47.1%로 가장 많았고 7일 이내에 2/3 이상인 70.6%가 사망하였다. 주 사망 원인은 생후 3일 이내에는 호흡곤란 증후군(23.5%), 생후 4-7일에는 폐출혈(9.8%), 생후 8-27일에는 패혈증(16.7%) 이었다. 평균 입원 기간은 57.7±26.0일 이었다. 결론: 최근 극소 저체중 출생아 특히 초극소 저체중 출생아의 증가를 보이고 있는 시점에서 시행된 본 연구를 통해 신생아 집중치료로 향상을 보이던 생존율이 최근 감소를 보이고 있음을 알 수 있었다. 향후 저체중 출생아의 향상을 위해서는 전문적 치료와 간호, 그리고 폐출혈, 패혈증 등의 합병증 저하를 위한 노력이 적극적으로 요구된다. Purpose: The survival rate of very low birth weight infants(VLBWI) has improved by advanced neonatal intensive care in level III hospital. We performed this study to evaluate the outcome including incidence, survival rate, mortality and morbidity of VLBWI and to get a help on more advanced care in neonatal intensive care unit(NICU). Methods: The retrospective review of medical records was analysed for 205 VLBWI(<1,500g) who were admitted to the NICU of Wonkwang University Hospital from January 2000 to December 2006. Results: The incidence of VLBWI was 4.2%. Overall survival rate was 75.0% and which was lower than other hospital. By birth weight, survival rate was 92.6% in over 1,250g which was higher same as other large hospital, however it was 18.2% in below 750g which was lower than others. By gestational age, survival rate was higher over 80% in over 29 weeks, however which was lower 38.9% in 25-26 weeks and there is no lived in below 24 weeks. Common morbidities were respiratory distress syndrome(RDS) 75%, intraventricular hemorrhage 31.7%, patent ductus arteriosus 29.3%, retinopathy of prematurity 28.8% in the order of frequency. Most common time of death was within 3days 47.1%, and 70.6% died within 7 days. Major cause of death was RDS 23.5% within 3 days, pulmonary hemorrhage 9.8% in 4-7 days, and sepsis 16.7% in 8-27 days. Mean admission duration was 57.7±26.0 days. Conclusion: Survival rate of VLBWI was much improved, but recently decreased a little. So, much efforts must be made with a skillful therapy and nursing care and to reduce a complications for increasing their survival rates.

소아에 발생한 척수신경초종 2례

황대성,강순애,오광수,김태영 圓光大學校 醫科學硏究所 1992 圓光醫科學 Vol.8 No.1-2

Neurilemmoma is the most frequent solitary tumor of the peripheral nerves, but it is extremely rare in children. It arises from Schwann cells, and has usually benign nature. There is suprisingly good recovery after total removal of the mass in patients with preoperative neurologic deficits. We experienced two cases of neurilemmoma in the spinal cord and report it with a review of the literature.

소아 급성 중독증에 관한 임상적 고찰

이순길,강순애,이미연,오광수,오연균,윤향석,김종덕 圓光大學校 醫科學硏究所 1993 圓光醫科學 Vol.9 No.1-2

A clinical study was performed on 72cases of acute poisoning who were admitted in pediatric department of Wonkwang University Hospital during the recent 6 years from Mar. 1986 to Feb. 1992. The results are as follows : 1) The peak incidence year was 1989(29%), October(19.4%) was a month of peak incidence in a year. 2) The sex ratio of male to female was 1.6 : 1, and age of peak incidence was from 1 to 2 years old(43%). 3) The most common cause of poisoning was accidental cause(86%). 4) The poisoning was occured most frequently from 14 : 00 to 18 : 00 O’clock. 5) The most frequent time interval from poisoning to visit to hospital was within 4 hours(68%). 6) The causative substances were drugs(27.8%) especially DDS(13.9%), insectisides(22.2%), acetic acid(5.5%), herbicides(4.2%) and rodenticides(4.2% ). 7) The chief complaints at admission were in order of frequence, nausea, vomiting, altered consciousness and cyanosis. 8) The abnormal laboratory finding at admission was AST above 50U/L in 7 patients. 9) The most frequent complication was aspiration pneumonia(8%).

능동적 가압-감압 심폐소생술

채장성,강동헌,이광수,권순애,김세경,임근우,박승현,오동렬,이기중,승기배,황주일,박규남,이원재,채규보 대한응급의학회 1994 대한응급의학회지 Vol.5 No.2

Background : Recent studies have demonstrated improved cardiopulmonary circulation during cardiac arrest with the use of a hand-held suction device(AMBU Cardio Pump) to perform active compression-decompression cardiopulmonary resuscitation in animal. The purpose of this study was to compare active compression-decompression with standard CPR during cardiac arrests in emergency department patients. Design : Patients in cardiac arrest in whom standard advanced cardiac life support failed were randomised to receive 2 minutes of either standard or active compression-decompression (ACD) CPR using hand-held suction device, followed by 2 minutes of the alternate technique. The ACD device was applied midsternum and used to perform CPR according to the guidelines of the American Heart Association : 80 compressions per minute, compression depth of 3.8 to 5cm, 50% duty cycle, and constant-volume ventilation. End-tidal carbon dioxide(ETCO2) concentration and hemodynamic variables were measured. In one case, Transcranial doppler sonography was used to assess cerebral blood flow velocity. Results : Twelve patients were enrolled. The mean ±SD ETCO2 was 8.33±2.72mmHg with standard CPR and 12.42±8.3mmHg with ACD-CPR(P<.001). Systolic arterial pressure with standard CPR was 74.75±11.31mmHg and with ACD-CPR, 88.58±16.91mmHg(P<.005). Diastolic arterial pressure with standard CPR was 2.66±6.14mmHg and with ACD-CPR, 1.16±8.11mmHg(P=NS). Base exess with standard CPR was -11.50±5.37 and with ACD-CPR, -11.42±5.37(P=NS). In one case, mean cerebral blood flow velocity with standard CPR was 25.2cm/sec, with ACD CPR, 30.5cm/sec. Conclusion : ACD-CPR is a simple manual technique that improved cardiopulmonary circulation in 12 patients during cardiac arrests.