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자발적 의약품 부작용 보고자료를 이용한 성별에 따른 부작용 발현 차이
연하림(Ha Rim Yeon),강상오(Sang Oh Kang),민경현(Kyung Hyun Min),최윤정(Yunjeong Choi),황보영(Boyoung Hwang),김현정(Hyun Jeong Kim),이경은(Kyung Eun Lee) 대한약학회 2020 약학회지 Vol.64 No.1
The aim of this study was to assess and characterize sex differences in adverse drug reactions (ADRs) reported to the Korea Institute of Drug Safety and Risk Management (KIDS). This retrospective pharmacoepidemiological study was performed using the Korea Adverse Event Reporting System (KAERS) database from the KIDS in 2014-2018. Variables used in the analyses include sex and age of patients, suspected drug, type and severity of ADR, and severity of ADR. A ratio of reports concerning women and men was calculated for ADRs reported. A dataset of 22 drugs selected from the FDA label and UpToDate?? database were requested to KIDS. Among 22 drugs, 17 of them were reported as suspected drugs to cause ADR and these were further analyzed in detail. The total reported number of ADRs was 241,974 and reports from female patients comprised of 54.5%. Aprepitant had the highest number of ADR reports (n=179,716), followed by fluorouracil (n=17,807), oxycodone (n=14,643) and cisplatin (n=14,191). Reports of serious adverse events were mostly from aprepitant and evidently high in female patients in aprepitant. Sex differences exist in ADRs based on KIDS-KAERS database which varies among drugs and type of ADRs. Further studies are warranted to examine details of clinical information of patients to conclude gender differences in adverse drug reactions.
사무직과 생산직 근로자의 영양실태 비교 및 건강 관련 요인 분석
김순경,연보영,장정희 대한영양사협회 2003 대한영양사협회 학술지 Vol.9 No.4
This study was carried out to collect information to establish a framework for meal management and nutritional service for prevention of chronic degenerative disease in the industrial workers. We investigated the health concerned life-style, nutrient intakes, anthropometry and biochemical parameters in the male workers in Korea by work condition. Anthropometric parameters of height, weight. waist, hip and triceps skinfold thickness were measured and bioched parameters including Urine pH. hemoglobin. blood glucose, total cholesterol GOT, GPT, 7-GPT and blood pressure were determind for 101 subjects(50 office workers : 33.9 yr, 51 laborers : 34.4 yr). To assess the nutrient intakes and diet quality of workers dietary intake was measured by one day 24-hour recall method. Result of anthropmetric parameters of height(P<0.01). weight(P<0.05). hp(P<0.05), TSF(P<0.01) were significantly higher in office workers than in laborers. Biochemical parameters were not significantly difference in both of them. Average daily nutrient intakes of both group was higher than the Korean RDA and report on 2001 National Health & Nutrition Survey. The calcim(P<0.0l), iron(P<0.05). vitamin A(P<0.01). vitamin B₁(P<0.01) and niacin(P<0.05) intakes in laborers were significantly higher than in office workers. Nutrition adequacy ratio(NAR), mean adequacy ratio(MAR) and index of nutritional quality(INQ) of laborers were higher than those of office workers. This results indicated that the onset possibility of chronic degenerative disease appeared higher in office workers. Therefore, meal menagement and nutritional service for prevention of chronic degenerative disease of industrial works needs to be more variant guidelines.
김순경,연보영 순천향대학교 기초과학연구소 2002 순천향자연과학연구 논문집 Vol.8 No.1
This study investigated to improve for nutritional service and nutrition education for prevention of chronic degenerative diseases. We compared difference in dietary habits, life-style behavior, nutrient intakes and health status of male industrial workers by work condition. Anthropometric parameters of height, weight, waist, hip and triceps skinfold thickness were measured for 101 subjects(50 office workers, 51 laborers). To assess the nutrient intake and diet quality of workers were measured by one day 24-hour recall method. The average age of the subjects was that office workers is 33.9 years, laborers is 34.4 years. Education levels were higher in office workers than in laborers. Result of anthropometric parameters of height(P<0.01), weight(P<0.05), hip(P<0.05), TSF(P<0.01) were significantly higher in office workers than in laborers. Smoking and alcohol drinking of subjects were not significant difference between office workers and laborers. Average daily nutrient intake of both group was higher than the Korean RDA. For calcium (P<0.01), iron (P<0.05), vitamin A(P<0.001), vitamin B1(P<0.01), niacin (P<0.05) was significantly higher in laborers than office workers. Nutrition adequacy ratio(NAR), mean adequacy ratio(MAR) and index of nutritional quality(INQ) of laborers were better than those of office workers. This results indicated that the onset possibility of chronic degenerative disease appeared difference by work condition.
국제 기아 돕기 캠페인의 효과에 미치는 긍,부정 프레이밍과 관여도의 영향-상호작용을 중심으로
이승조 ( Seung Jo Lee ),연보영 ( Bo Young Yeon ),구세희 ( Se Hee Koo ) 한국감성과학회 2010 감성과학 Vol.13 No.1
본 연구는 국제 기아 돕기 캠페인을 대상으로 긍·부정 프레이밍의 영향과 관여도와의 상호작용을 조사하였다. 이론적으로 국제 기아 돕기 캠페인은 위험 회피와 연관된 행동이므로 긍정 프레이밍이 더욱 유효할 것이라는 주장과 돕기 행동은 부정적 감성의 소구가 중요하기 때문에 부정적 프레이밍이 더욱 유효할 것이라는 상충된 예측을 연구를 통해 밝혀내고자 하였다. 연구는 실험으로 설계되었으며, 실험 참가자들은 기부를 하지 않았을 때 지속될 기아 어린이들의 고통을 강조하거나, 기부를 하였을 때 기아 어린이들이 얻을 수 있는 기쁨과 안도를 강조한 캠페인에 각각 노출되었다. 실험 결과는 먼저 긍·부정 프레이밍이 태도나 행위 의도에 영향을 주지 않는 것으로 나타났지만 관여도와 상호작용은 유의미한 것으로 나타났다. 하지만 그 상호작용이 태도와 행위 의도사이에 상반된 방향을 보이는 예상치 못한 결과가 나타났다. 태도에서는 관여도가 높은 집단에서는 부정적 프레이밍이, 관여도가 낮은 집단에서는 긍정적 프레이밍이 더 효과적으로 나타났다. 반면, 행위 의도에서는 그 방향이 반대로 나타나, 관여도가 높은 집단에서는 긍정적 프레이밍이, 관여도가 낮은 집단에서는 부정적 프레이밍이 더 효과적이라는 결과가 도출되었다. 이러한 결과가 내포한 의미와 국제 기아돕기 캠페인 제작에 적용할 수 있는 실용적 의미에 대해 논의하였다. This study investigates how framing and the interaction with involvement influences responses toward a help campaign. There could be two possible predictions about the results of framing. One is that, because helping is a risk avoidance behaviors, the positive framing would dominant or the other is that, because helping is mainly mediated by negative emotions such as sadness or guilty, the negative framing would be preferred. The present research was to solve the conflicting predictions and was conducted with a experimental design. The participants were exposed to a campaign emphasizing either positive aspects of the help or negative contexts which would be maintained without any help. The results were that the main effect of framing was not existent, but the significant interaction with involvement on responses was found. The interaction of framing and involvement, though, included unexpected inconsistency between the results of attitude and behavioral intention. The theoretical and practical meanings of the results were discussed.