Comparison of the Impact of the Anesthesia Induction Using Thiopental and Propofol on Cardiac Function for Non-Cardiac Surgery

양현숙,김태엽,방승호,유가연,오정식,김수녕,양정현 한국심초음파학회 2014 Journal of Cardiovascular Imaging (J Cardiovasc Im Vol.22 No.2

Background: Thiopental and propofol have been widely used for general anesthesia induction, but their impacts on cardiacfunction have not been well described. A recent study speculated that anesthesia induction using propofol 2 mg/kg transientlyreduced left ventricular (LV) contraction by analyzing tissue Doppler-derived imaging (TDI) during induction phase. Thepurpose of this study was to analyze and to compare the impacts of propofol- and thiopental-induction on LV function. Methods: Twenty-four female patients with normal LV function undergoing non-cardiac surgery were randomly administeredintravenous bolus thiopental (5 mg/kg, Thiopental-group, n = 12) or propofol (2 mg/kg, Propofol-group, n = 12) for anesthesiainduction. TDI of septal mitral annular velocity during systole (S’), early diastole (e’) and atrial contraction (a’) were determinedby transthoracic echocardiography before and 1, 3, and 5 minutes after thiopental/propofol administration (T0, T1, T2, and T3,respectively). Results: The bispectral index and systolic blood pressure declined significantly during anesthesia induction in both groups,however, more depressed in Thiopental-group compared with those in Propofol-group at T2 and T3 (all, p < 0.05). Among TDItwo parameters demonstrated a significant inter-group difference: the S’ in propofol was lower than that in Thiopental-group atT3 (p = 0.002), and a’ velocities were persistently lower in Propofol-group, compared with same time values in Thiopental-group(T1, T2, and T3: p = 0.025, 0.007, and 0.009, respectively). Conclusion: Anesthesia induction using propofol revealed a more persistent and profound decline of LV and atrial contractionthan that using thiopental. Further studies are needed to understand the clinical implication.

고품질의 신선한 유제품 개발만이 수입개방에 맞서는 유일한 대응책

양현숙,Yang, Hyeon-Suk 한국유가공협회 1994 牛乳 Vol.59 No.-

아동상담자가 지각하는 수퍼비전 내용과 수퍼바이저 역할에 대한 인과분석

양현숙,이선미 미래유아교육학회 2004 미래유아교육학회지 Vol.11 No.4

이 연구는 아동상담자들이 지각하는 수퍼비전의 내용과 수퍼바이저 역할에 대한 인과적 관계를 구명하는데 그 목적이 있다. 본 연구의 대상자는 상담센터, 아동임상 치료실, 사회복지기관 등에서 근무하는 60명의 아동상담자이다. 수집된 자료의 검증은 Pearson 상관분석, 중다회귀분석과 경로분석에 의해 이루어졌다. 본 연구의 결과는 다음과 같다. 첫째, 아동상담자의 학력과 상담경력은 내용 지각과 관계가 없지만, 발달 수준과 지각간에는 직접적인 인과관계가 있다. 둘째, 상담경력은 수퍼바이저 역할 지각과 간접적인 인과관계를, 상담자의 발달 수준은 수퍼바이저 역할 지각과 직접적인 영향을 주는 변인으로 나타났다. 결과적으로 아동상담자의 높은 자질과 긍정적이고 적절한 역할은 이들의 상담에 대한 발달 수준을 높이기 위한 교육과 훈련이 중요하다는 것이다. The present study was undertaken to investigate the causal relationship of the supervision contents and supervisor's roles perceived by child counselors. The research questions of the study were as follows. First, how much the effect of the educational background, the degree of counseling experience, and developmental level of child counselor on their perception to supervision content? Second, how much the effect of the educational background, the degree of counseling experience, and developmental level of child counselor on their perception to supervisor' roles is it The subject of the study were 60 child counselors who are working at counseling center, the child psychiatry, the social welfare center, and so on. The counselor's level was measured though the Korean Counselor Level Questionnaire developed by Shim(1998). The supervision contents and supervisor's roles rated though the questionnaires by Bang(1996). The data were analyzed by Pearson's correlation, multiple regression analysis, and path analysis. The results if the study were as follows First, nothing expect for child counselor's developmental level had significantly direct effect on child counselor's perception to supervision contents and supervisor' roles. Second, the direct causal relationship between the child counselor's perception and counselor's developmental level. Also, child counselor's perception to supervision contents and supervisor' roles was indirect causal relationship with their degree of counseling experience.

Non-invasive Myocardial Strain Imaging to Evaluate Graft Failure in Cardiac Xenotransplantation

양현숙,지현근,김준석,김완섭,박정환,신기철,박경식,이선원,조가희,박완제,오건봉,안규리,윤익진 대한이식학회 2017 Korean Journal of Transplantation Vol.31 No.1

Background: The shortage of human hearts for allotransplantation makes xenotransplantation a possible option for controllable organ providers. To detect acute xenograft rejection, invasive biopsy seems inevitable; however, this occasionally results in poor incision wound healing or infection. To date, no method of noninvasive imaging for early detection of xenograft rejection has been established. We hypothesized that ultrasound speckle tracking would better detect xenograft failure than routine left ventricular ejection fractions (EF). Methods: From August 2013 to July 2015, a total of six cardiac heterotopic xenotransplants ( 1, 3-galactosyltransferase gene-knockout porcine heart) into cynomolgus monkeys were monitored with echocardiography every 3 to 7 days. M-mode and two-dimensional (2D)-EF measurements and myocardial strain analyses were performed. Cardiac xenograft pathology was reviewed from the immediate postoperative biopsy, as well as the necropsy. Results: Myocardial speckle tracking analysis was feasible in all six cases. The longest survival was 43 days. Only one pathology- proven immunologic rejection occurred. Cardiac xenograft failure appeared as two types: a dilated pattern with decreased EF or a myocardial-thickening pattern with preserved EF. Both antibody-mediated rejection (n=1) and sepsis-induced myocardial dysfunction (n=2) revealed decreased radial or circumferential strains, but normal-range EF. Xenograft functional decline was significant with respect to radial or circumferential strain (P=0.028), but not to conventional M-mode or 2D-EFs (P=0.600, P=0.340, respectively). Conclusions: Radial and circumferential strains were significantly decreased in both types of xenograft failure, regardless of EF. Further studies are warranted to correlate the strain analysis and immunopathological details.

'93 유제품 시장 전망

양현숙,Yang, Hyeon-Suk 한국유가공협회 1992 牛乳 Vol.51 No.-

Prognostic Role of High-sensitivity Cardiac Troponin I and Soluble Suppression of Tumorigenicity-2 in Surgical Intensive Care Unit Patients Undergoing Non-cardiac Surgery

양현숙,허미나,이아람,김한아,김자연 대한진단검사의학회 2018 Annals of Laboratory Medicine Vol.38 No.3

Background: The prognostic utility of cardiac biomarkers, high-sensitivity cardiac troponin I (hs-cTnI) and soluble suppression of tumorigenicity-2 (sST2), in non-cardiac surgery is not well-defined. We evaluated hs-cTnI and sST2 as predictors of 30-day major adverse cardiac events (MACE) in patients admitted to the surgical intensive care unit (SICU) following major non-cardiac surgery. Methods: hs-cTnI and sST2 concentrations were measured in 175 SICU patients immediately following surgery and for three days postoperatively. The results were analyzed in relation to 30-day MACE and were compared with the revised Goldman cardiac risk index (RCRI) score. Results: Overall, 30-day MACE was observed in 16 (9.1%) patients. hs-cTnI and sST2 concentrations differed significantly between the two groups with and without 30-day MACE (P <0.05). The maximum concentration of sST2 was an independent predictor of 30-day MACE (odds ratio=1.016, P =0.008). The optimal cut-off values of hs-cTnI and sST2 for predicting 30-day MACE were 53.0 ng/L and 182.5 ng/mL, respectively. A combination of hs-cTnI and sST2 predicted 30-day MACE better than the RCRI score. Moreover, 30-day MACE was observed more frequently with increasing numbers of above-optimal cut-off hs-cTnI and sST2 values (P <0.0001). Reclassification analyses indicated that the addition of biomarkers to RCRI scores improved the prediction of 30-day MACE. Conclusions: This study demonstrates the utility of hs-cTnI and sST2 in predicting 30-day MACE following non-cardiac surgery. Cardiac biomarkers would provide enhanced risk stratification in addition to clinical RCRI scores for patients undergoing major non-cardiac surgery.

개방 맞이한 국내치즈시장-값싼 한국형치즈 개발 서둘러야

양현숙,Yang, Hyeon-Suk 한국유가공협회 1993 牛乳 Vol.55 No.-

RF 모듈 방식의 선박용 냉동 컨테이너 원격 감시시스템 개발

양현숙,임현정,김건우,권영괄,김동묵,이성근,Yang, Hyun-Suk,Lim, Hyun-Jung,Kim, Kun-Woo,Kwon, Yeong-Gwal,Kim, Dong-Mook,Lee, Sung-Geun 한국마린엔지니어링학회 2007 한국마린엔지니어링학회지 Vol.31 No.4

This paper describes a development of ship's refer-container remote monitoring system(RRMS). This system consists of Master, repeater with a switched mode power supply(SMPS) and slave terminal. Slave terminal is composed of wireless MODEM and microprocessor part, checks its conditions like temperature. humidity & etc through the interrogate port(IP) of refer-container. and transmits their data to master. Repeater's role is that connect so that signal which is transmitted from Slave Terminal by Master may not receive electric wave interference by container boxes. We verify the effectiveness of proposed system through the experimental works in container yard and ship.

2009년 개정 교육과정 성취기준에 따른 중학교 1학년 영어교과서의 쓰기활동 분석

양현숙,표경현 한국외국어교육학회 2013 Foreign languages education Vol.20 No.4

The purpose of this study was to analyze writing activities of 1st grade middle school English textbooks based on the achievement standards of the 2009 revised National Curriculum and provide suggestions for improvements of textbooks. In this study, seven textbooks out of twelve were selected and their writing activities were analyzed as to whether they stick to the guidelines of the 2009 revised National Curriculum. For this purpose, specific focuses of the current study were 1) to look into writing activities based on achievement standards stipulated in the 2009 revised National Curriculum, and 2) to investigate the ratio of integrated writing activities to separate writing activities ones. The results of the analysis revealed that most of the writing activities seemed suitable based on learners' real-life situations for achievements standards; however, the types of writing activities were rather simple, mainly focusing on given words. Next, there were not only separate writing activities but also a variety of integrated activities such as listening-writing, speaking-writing, and reading-writing activities. At the end of the paper, a few suggestions were provided to improve the qualities of writing activities in the textbooks.

포스타 전시 발표 : 순환기, 호흡기 ; 고립성 폐결절상을 보인 콕시디오이데스진균증(coccidioidomycosis) 1예

양현숙,이재천,심태선,임채만,이상도,고윤석,김우성,김동순,김원동,손광현 대한내과학회 1998 대한내과학회 추계학술대회 Vol.1998 No.1