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한국 정신분열병 환자에서의 혈중 Homocysteine, 엽산, Vitamin B12 농도 비교연구
김태호,이영식,송성용,민경준,기백석,나철,채석래,Kim, Tae Ho,Lee, Young Sik,Song, Seong Yong,Min, Kyung Joon,Kee, Baik Seok,Na, Chul,Chae, Seok Lae 대한생물정신의학회 2004 생물정신의학 Vol.11 No.2
Objective:There have been a kind of transmethylation theory that high homocysteine serum concentration affects schizophrenia by neurotoxic mechanism and clinical reports that some schizophrenic patients with high homocysteine were improved by high folate ingestion. This study was done to confirm previous research results and find the clinical characteristics of schizophrenia showing high serum homocysteine and low folate. Method:We compared the serum levels of homocysteine, folate and vitamin B12 level between 234 schizophrenic patients(male 99, female 135) group and 234 normal controls(male 99, female 135) group. The subjects of two groups were age and sex matched. The evaluated clinical characteristics items were sex, age, onset of disease, hereditary loading, disease course, hallucination and subtype of schizophrenia. Results:1) Homocysteine level of the schizophrenia group was significantly higher than the normal control group and folate level of the schizophrenia group was significantly lower than the normal control group. Homocysteine level was more negatively correlated with folate level in the schizophrenia group than the normal control group. 2) The percentage of high homocysteine(above 12.46umol/L;90 percentile of normal control) was 33.8% of schizophrenia patients and 51.5% of male schizophrenia. The percentage of low folate(below 3.8nM/L;bottom tertile of normal control) was 66.2% of schizophrenia. 3) In low folate group and not-low folate group, schizophrenia showed significantly higher homocysteine level than normal control. Especially, low folate schizophrenia group showed significantly higher homocysteine level than low folate normal control group. Conclusions:Some schizophrenia patients with high serum homocysteine may be genetic defector and having low folate serum level. In that case, folate ingestion could be a good management for clinical improvement.
테이블형 다단 드롭 시스템을 이용한 저소음 보-슬래브 거푸집의 구성부재 성능 및 현장적용에 관한 실험적 연구
류화성,정우진,김득모,송성용,신상헌,Ryu, Hwa-Sung,Jeong, Woo-Jin,Kim, Deuck-Mo,Song, Seong-Yong,Shin, Sang-Heon 한국건축시공학회 2017 한국건축시공학회지 Vol.17 No.4
콘크리트 건축물 공사에 있어, 거푸집공사는 전체공사비의 10%를 차지하는 중요한 공정이다. 최근의 건축물은 대형화, 고층화가 이루어지고 있다. 이러한 거푸집공사의 고효율과 안전성을 위하여 거푸집공정의 시스템화가 이루어지고 있으나, 여전히 인명사고와 해체공정에서 발생하는 소음 민원이 빈번히 발생하고 있으며, 이러한 문제의 해결을 위하여 대부분 해외기술에 의존하여 국내 건설현장 여건을 고려하지 않는 관계로 외면되어 기존 거푸집 공법을 답습하고 있는 실정이다. 본 연구는 공정개선, 안전성 향상 및 해체소음 저감이 가능한 슬래브, 보 전용 테이블형 다단 드롭 시스템 거푸집을 개발하고 시스템 내에 사용되는 주요 부재인 장선 멍에와 동바리의 물성을 평가하고, 이 시스템의 현장 적용을 위한 해체공정에서의 소음을 기존 공법과 비교 평가하는 연구로서 실험결과, 멍에 빔과 동바리 모두 슬래브 및 보 타설용 가설재로 사용하기에 충분한 내력이 있는 것으로 나타났으며, 평균소음도가 기존 공법에 비해 10dB(A) 이상 저감되는 것으로 확인되었으며 타설 시의 처짐량을 측정한 결과, 기존 공법 대비 처짐이 저감되는 것을 확인하였다. In concrete construction work, formwork is an important process that accounts for 10% of the total construction cost. Recent buildings are becoming bigger and higher. In order to maximize the efficiency and safety of this formwork, the system of formworking has been systematized. However, the human accidents and the noise complaints arise from dismantling processes frequently occur. In order to solve these problems, most of them are dependent on foreign technology, but they do not take into consideration the conditions of domestic construction site. In this study, we developed a table type multi-drop system form for a slab and beam which can improve the process, safety and reduction of disassembly noise, and evaluated the physical properties of the main members which are used in the system. The results of this study show that there is sufficient strength to be used as a slab and a laying material for both a yoke beam and a supporting post. The noise level is improved compared to existing method.
조남수,김용배,조수형,송민엽,송성용 大韓應急醫學會 1996 대한응급의학회지 Vol.7 No.1
Endotracheal intubation has been used widely for the maintenance of airway in the emergency patient and CPR in the acute airway obstruction patient and to treat respiratory insufficiency. Endotracheal intubation has many advantages but it may cause several complications which rate about 4% of endotracheal intubation patient. Among these complications, laryngeal granuloma is a relatively rare complication arising about 1 case per 10,000∼20,000 cases. Authors report a case of laryngeal granuloma which developed after endotracheal intubation required during emergency treatment. Case: A 55-year old female patient visited Chosun University Hospital Emergency Room complaining of dyspnea, cyanosis and sweating on Feb. 8th 1995. According to past history, she had a little obesity, dyspnea on exercise and mild hypertension. At arrival, blood pressure was 240/110mmHg, pulse rate 150 rates/min, respiratory rate 12/min, body temperature 36.5℃ and cyanosis with sweating on whole body was observed. And the mental state was semicoma. At 5 minutes after arrival, sudden respiratory arrest developed and immediate endotracheal intubation which emergency treatment was performed it was difficult to intubate endotracheally due to short neck and obesity. At 1 hour after arrival, general condition of the patient recovered well and extubation was done. The patient was transferred to internal medicine department and discharged after 12 days of medical treatment. At 2 months after discharge, the patient felt a progressive hoarseness and foreign body sensation of larynx. She was diagnosed as laryngeal granuloma at ENT department of Chosun University. She underwent the surgical operation and discharged in good health after 7 days of admission.
성인 남자에서 척추경막외 천자침을 사용시 피부에서 경막외강과 지주막하강까지의 거리
송광수,송민엽,임경준,정종달,김용일,송성용 朝鮮大學校 附設 醫學硏究所 1996 The Medical Journal of Chosun University Vol.21 No.1
The purpose of the present study was to examine and evaluate the distance from the skin to the epidural space, to the subarachnoid space and the epidural width using a combined spinal-epidural technique. And to evaluate the correlation with age, height, weight and the ponderal index (PI= weight/height ratio). Combined spinal-epidural anesthesia was performed on 30 males in the ASA class I-II patients scheduled for lower extremity surgery. The age, height, weight and PI were recorded. The epidural space was identified using midline approach at the L_(3-4) interspace with an 18G Tuohy needle and the spinal needle was introduced through the Tuohy needle. After free flow of cerebrospinal fluid. 3ml of 0.5% heavy bupivacaine was injected into the subarachnoid space. We used following parameters : the distance from the skin to the tip of the Tuohy needle (skin to epidural space : SE) and to the distal aperture of the spinal needIe (skin to subarachnoid space : SS) and the distance from recognition of negative pressure to free flow of cerebrospinal fluid (epidural width : EW) were measured. Afber measurement, the spinal needle was withdrawn and the epidural catheter was inserted. The mean SE, EW and SS were found to be 4.74 cm, 0.79 cm and 5.53 cm respectively, which significantly correlated with the weight and PI, but not with age and height. It is concluded that if the SE, SS and EW are predictable after weight and the PI are measured, an accurate placement of the epidural needle into epidural space may reduce the complications of spinal or epidual anesthesia as well as providing a safe anesthetic management.