인위적으로 겹쳐져 공중에 매달린 그래핀의 전기역학 특성

서미리,권민희,최민희,신동훈,커스티맥알리스터,이상욱 한국진공학회 2017 한국진공학회 학술발표회초록집 Vol.2017 No.2

Long-Term Outcome of Amyotrophic Lateral Sclerosis in Korean Subjects

서미리,최원아,최영철,이장우,홍정화,박지현,강성웅 대한재활의학회 2017 Annals of Rehabilitation Medicine Vol.41 No.6

Objective To report the latest long-term outcome of amyotrophic lateral sclerosis (ALS) and to analyze the predictors of prognosis.Methods Subjects who were diagnosed with ALS between January 2005 and December 2009 at a single institute were followed up until death or up to December 2014. Data regarding age, sex, date of onset, date of diagnosis, presence of bulbar symptoms on onset, date of initiation of non-invasive ventilation (NIV), and the date of tracheostomy were collected. Survival was assessed using Kaplan-Meier curves and multivariate analyses of the risk of death were performed using the Cox proportional hazards model. Results Among 212 suspicious subjects, definite ALS was diagnosed in 182 subjects. The survival rate at 3 and 5 years from onset was 61.5% and 40.1%, respectively, and the survival rate at 3 and 5 years post-diagnosis was 49.5% and 24.2%, respectively. Further, 134 patients (134/182, 73.6%) were initiated on NIV, and among them, 90 patients (90/182, 49.5%) underwent tracheostomy. Male gender and onset age of ≥65 years were independent predictors of adverse survival.Conclusion The analysis of long term survival in ALS showed excellent outcomes considering the overall poor prognosis of this disease.

Ultrasound-Guided Myofascial Trigger Point Injection Into Brachialis Muscle for Rotator Cuff Disease Patients With Upper Arm Pain: A Pilot Study

서미리,장원혁,최효선,이상철 대한재활의학회 2014 Annals of Rehabilitation Medicine Vol.38 No.5

Objective To assess the efficacy of trigger point injection into brachialis muscle for rotator cuff disease patients with upper arm pain.Methods A prospective, randomized, and single-blinded clinical pilot trial was performed at university rehabilitation hospital. Twenty-one patients clinically diagnosed with rotator cuff disease suspected of having brachialis myofascial pain syndrome (MPS) were randomly allocated into two groups. Effect of ultrasound (US)-guided trigger point injection (n=11) and oral non-steroidal anti-inflammatory drug (NSAID) (n=10) was compared by visual analog scale (VAS).Results US-guided trigger point injection of brachialis muscle resulted in excellent outcome compared to the oral NSAID group. Mean VAS scores decreased significantly after 2 weeks of treatment compared to the baseline in both groups (7.3 vs. 4.5 in the injection group and 7.4 vs. 5.9 in the oral group). The decrease of the VAS score caused by injection (ДVAS=-2.8) was significantly larger than caused by oral NSAID (ДVAS=-1.5) (p<0.05).Conclusion In patients with rotator cuff disease, US-guided trigger point injection of the brachialis muscle is safe and effective for both diagnosis and treatment when the cause of pain is suspected to be originated from the muscle.

Multiplex Ligation-Dependent Probe Amplification in X-linked Recessive Muscular Dystrophy in Korean Subjects

서미리,강성웅,이경아,김은영,정지호,최원아 연세대학교의과대학 2017 Yonsei medical journal Vol.58 No.3

Purpose: Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) are similar genetic disorders whose patternsof mutation and disease phenotypes might be expected to show differences among different countries. We analyzed multiplexligation-dependent probe amplification (MLPA) data in a large number of Korean patients with DMD/BMD. Materials and Methods: We obtained 130 positive MLPA results (86 DMD, 27 BMD, and 17 female carriers) from 272 candidates (237 clinically suspected patients and 35 possible female carriers) who took part in this study. We analyzed the mutation patterns among 113 patients diagnosed by MLPA and calculated deletion/duplication percentages from a total of 128 patients, including 15 patients who were diagnosed using methods other than MLPA. We also analyzed hot spot locations among the 130 MLPA-positiveresults. Results: Most mutations were detected in a central hot spot region between exons 44 and 55 (80 samples, 60.6%). Unlike previous reports, a second frequently observed hot spot near the 5’-end was not distinctive. MLPA detected deletions in specific exons in 92 patients with DMD/BMD (71.8%) and duplications in 21 patients (16.4%). Conclusion: Our MLPA study of a large number of Korean patients with DMD/BMD identified the most frequent mutation hot spot, as well as a unique hot spot pattern. DMD gene mutation patterns do not appear to show significant ethnic differences.

北魏平城宫研究成果的比较与辨析

徐美莉,马志强 호남사학회 2011 역사학연구 Vol.42 No.-

Scholars have different understanding about the Western Palace, the Wanshou Palace and the Eastern Palace in the imperial palace of Beiwei’ Pingcheng City. Some people think Taizu and Taizong’s imperial palace was named the Western Palace because it was in west of the city. The Wanshou Palace built on the place of the Old Eastern Palace by Shizu was moved to east of the city. Gaozu’s imperial palace moved to west of the Wanshou Palace. And fix the Western Palace’ position in west, the Wanshou Palace in east, Gaozu’s imperial palace in middle part of the Caochang City. Some scholars think the Western Palace just was a traditional name. Others think the imperial palace didn’t move far during the period from Taizu to Gaozu,which is supported more strongly. Some scholars think Taizu built the Eastern Palace to east of the Western Palace but others don’t agree. Some scholars think the Eastern Palace built by Shizu was to east of the Guocheng, even its site is in Gucheng village which is located to east of Yuhe. Scholars agree that the Tianwen Palace, the Yong’an Palace, the Taihua Palace , and the Taiji Palace was the main hall successively during the period from Taizu to Gaozu 북위 평성궁의 서궁 만수궁 동궁에 대한 연구와 이해에 있어 각 연구자들의 견해는 상당한 차이가 있어왔다. 한 연구에 의하면, 북위 태조 태종시기의 황궁인 서궁은 평성의 서부지역에 있는 이유로 그렇게 명명되었고, 세조시기 동궁의 토대 위에 건립된 만수궁은 평성 동부지역에, 문명태후 풍씨 효문제 시기의 황궁은 대략 평성 서부지역에 위치하였는데 이러한 세 곳에 위치한 황궁은 현재의 산서성 대동시 운동장을 중심으로 각각 서부 동부 그리고 약간 동쪽으로 치우친 중부지역에 자리잡았다는 것이다. 다른 연구자의 견해에 의하면, 북위 평성시대 황궁은 각 시기별로 그렇게 나눠지는 것이 아니며 이에 대해서는 비교적 많은 문헌 사료가 뒷받침한다는 것이다. 동궁 문제에 있어서는 태조시기 서궁의 동쪽에 건립하였다는 주장과 태조 태종시기 태자궁은 존재하지 않았고 세조시기 태자를 위해 건립한 동궁만이 북위 평성시대의 진정한 의의를 가진 동궁이라는 주장이 있다. 그리고 세조시기 건립된 동궁은 평성 동곽의 동쪽에 있었고 그 위치도 현재의 대동시 어하 동쪽의 고성촌이라는 연구자의 견해도 있다. 태조시기로부터 고종시기에 이르기까지 천문전 영안전 태화전 태극전이 선후 각기 정전으로서 자리매김 되었다는 견해에 대해 연구자 간의 기본 시각은 일치한다.

게임성향 인터넷 배너광고의 표현요소 도출

서미라 한국디지털정책학회 2012 디지털융복합연구 Vol.10 No.8

게임캐릭터의 패션스타일 유형 및 특성

서미라,김애경,Seo, Mi-Ra,Kim, Ae-Kyung 한국디지털정책학회 2015 디지털융복합연구 Vol.13 No.2

이 연구는 게임 캐릭터의 패션스타일을 분석하여 게임에 적합한 유형화를 제안하고, 유형별 특성을 정의하고자 한다. 수집된 자료를 유사한 스타일로 그룹핑하여 대표성을 띤 용어로 게임 캐릭터스타일을 새롭게 명명하였으며, 명명된 스타일은 캐릭터의 의상, 헤어스타일, 액세서리를 중심으로 Creative Style, Attractive Style, Grotesque Style, Usual Style, Suit Style 등 5가지로 분류하여 분석하였다. Creative Style은 창의적인 디자인으로 일부를 제거 및 첨가한 독창적인 스타일, Attractive Style은 노출이 많은 디자인, 신체에 피트한 디자인으로 성적인 매력을 표현하는 스타일, Grotesque Style은 엽기적이고 괴기스러우며, 음침한 분위기를 나타내는 스타일, Usual Style은 평범하고 현실적인 스타일, 마지막으로 Suit Style은 전신을 둘러싼 갑옷 스타일이다. 이 연구를 통해 캐릭터 패션스타일에 대해 게이머와 개발자간의 견해 차이를 좁혀 게임디자인의 경쟁력을 높일 수 있다. This paper aims to propose the typology suitable for games by analyzing the fashion styles of game characters and define the characteristics by type. The data collected was classified into the style groups with similarities, and the game character styles were named using representative terms. Then, five styles were identified and analyzed with the focus on clothing, hairstyle, and accessories: Creative Style, Attractive Style, Grotesque Style, Usual Style, and Suit Style. Creative Style was the unique style with partial addition or removal as the creative design. Attractive Style expressed the sexual attraction by design with significant exposure of body parts and skintight design. Grotesque Style showed grotesque, eerie, and dreary design. Usual Style was a plain and practical style. Finally, Suit Style was a kind of armor covering the whole body. The analysis results in this paper will bridge the difference of opinions between gamers and developers related to fashion style and, finally, help to enhance the competitiveness of game design.

Lorazepam 과 Diphenhydramine 의 추체외로증후군에 대한 효과비교

서미라,최보문,백인호 대한신경정신의학회 1986 신경정신의학 Vol.25 No.1

In this study, a comparative evaluation on clinical efficacy between intravenous lorazepam and diphenhydramine for extrapyramidal symptoms occurring on neuroleptic therapy was made. Subjects were consisted of 42 cases in cluding 8 males and 34 females. They were under double - blind procedure, given single injections o f 4 miligrams of lorazepam ( 21 cases) and 50 miligrams of diphenhydramine ( 21 cases) seperately. The effects were evaluated by Extrapyramidal Symptoms ( EPS ) Rating Scale for extrapyramidal Symptoms as well as by the Brief Psychiatric Rating Scale ( BPRS ) for psychotic symptoms and signs. The results were as follows : 1) Most of extrapyramidal symptoms induding parkinsonian symptoms, akathisia and dystonia were noted to be significantly improved 60 minutes after injection on EPS Rating Scale scores. 2) BPRS evaluation 60 minutes after injection resulted in significant reduction of the total mean scores in both groups, although no significant difference can be made in terms of efficacy between the group when the two groups were compared. 3) Clinically it can be suggested that the seda-tive effect of diphenhydramine was less than that of lorazepam. The above mentioned results suggest that lorazepam and diphenhydramine may well be the drugs of choice for the treatment of extrapyramidal symptoms occurring on the neuroleptic therapy.

유니버설 디자인 관점에서 본 국내 시도 교육청의 웹 접근성 실태에 관한 연구

서미라 한국디지털정책학회 2013 디지털융복합연구 Vol.11 No.5

집중기획 - 외국산치즈디저트카페 열풍 이대로 괜찮은가

서미랑,Seo, Mi-Rang 한국낙농육우협회 2017 낙농·육우 Vol.37 No.8