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      • SCOPUSKCI등재

        propylthiouracil 유발성간염 2예

        정규원(Kyu Won Chung),정환국(Whan Kook Chung),백상홍(Sang Hong Baek),박석영(Suk Young Park),임계순(Kae Soon Im),백남종(Nam Jong Paek),김영우(Young Woo Kim),손호영(Ho Young Son) 대한소화기학회 1986 대한소화기학회지 Vol.18 No.2

        Propylthiouracil-induced hepatitis is an uncommon entity. Two cases of PTU-induced hepatitis have been observed. One case presents a histological picture resembling chronic active hepatitis; the other acute cholestatic hepatitis proven by rechallenge and histological finding but reveal normal lymphocyte transformation test: clinical course in two cases was uneventful with spontaneous remission. Despite its rarity, the disease should be suspected in the patient receiving PTU in whom clinical or labarotory evidence of hepatocellular injury is present.

      • SCOPUSKCI등재

        국소 진행된 간암의 방사선 온열치료성적

        장홍석(Hong Seok Jang),윤세철(Sei Chul Yoon),강기문(Ki Mun Kang),유미령(Mi Ryeong Ryu),김성환(Sung Hwan Kim),백남종(Nam Jong Baek),윤승규(Seung Kyoo Yoon),김부성(Boo Sung Kim),신경섭(Kyung Sbu Shinn) 대한방사선종양학회 1994 Radiation Oncology Journal Vol.12 No.1

        Purpose : The aim of this study is to analyze the clinical results of thermo-irradiation treatment for surgically unreserctable advanced hepatoma with or without hepatic arterial chemo-embolization (HACE), chemotherapy (CT) and interferon (IFN) therapy. Materials and Methods : Between February 1990 and December 1992. 45 patients with surgically unresectable advanced hepatomas were treated by thermo-irradiation with or without hepatic arterial chemo-embolization and other treatment modalities. Among them, We analyzed retrospectively 24 patients who received more than three times of hyperthermias. Mean age was 50 years (range : 18-71 years) and male to female ratio was 20:5. In the study, treatment was administered as follows : 3patients received radiation therapy(RT) and hyperthermia (HT). 3 received RT+HT+CT. 3received RT+HT+HACE. 1received RT+HT+CT+HACE. 2 received RT+HT+CT+IFN. 10 received RT+HT+HACE+IFN. 3 received RT+HT+CT+HACE+IFN. Radiation therapy was done by a 6 MV linear accelerator. Patients were treated with daily fractions of 180 cGy to doses of 11gy-50Gy (median 30Gy). Local hyperthermia was done by HEH-500C(Omron Co.Japan), 30-45 min/session, 2 sessions/wk and the number of HT sessions ranged from 3 to 17 (median 7 times). 15 patients of 25 were followed by abdominal CT scan or abdominal ultra-sonogram. The following factors were analyzed : Age, histologic grade, sex, number of hyperthermia, total RT dose, hepatic arterial chemo-embolization. Results : Of 25 patients, there were observed tumor regression (partial response and minimal response) in 6(24%), no response in 8(32%), progression in 1(4%) and not evaluable ones in 10(40%) radiographically. The over all 1-year survival was 25%, with a mean survival of 33 weeks. The treatment modes of partial and minimal responsive patients (PR+MR) were as follow : Two were treated with RT+HT+HACE 2 were done with RT+HT+HACE+IFN Remaining 2 were treated with RT+HT+CT+HACE+IFN. The significant factor affecting the survival rate were RT dose (more than 25 Gy), HACE, number of HT(above 6 times), responsiveness after treatment (PR+MR). Age, sex, histologic differentiation, chemotherapy, interferon therapy were not statistically significant factors affecting the survival rate. Conclusion : Although follow-up duration was short, the thermo-irradiation with/without hepatic arterial chemo-embolization was well tolerated and there were no serious complications. In future, it is considered the longer follow up and prospective, well controlled trials should be followed to evaluate the efficacies of survival advantage.

      • SCOPUSKCI등재

        위 Anisakis 증 5예

        선희식(Hee Sik Sun),정인식(In Sik Chung),한석원(Suk Won Han),안병민(Byung Min Ahn),김재광(Jae Kwang Kim),최성호(Sung Ho choi),심규식(Gyu Sik Shin),백남종(Nam Jong Baek),지영희(Young Hee Jee),장은덕(Eun Duk Chang) 대한소화기학회 1989 대한소화기학회지 Vol.21 No.3

        Anisakis is generally considered to be a parasite of marine mammals and not normally found in man. It is possible for Anisakis larva to be transmitted to man through eating raw sea fish which is preferred by Korean people. The clinical symptoms are characterized by severe cramping abdominal pain, nausea, and vomiting. Recently we experienced 5 cases of acute gastric anisakiasis and all patients had a history of ingestion of raw sea fish and suffered from acute severe epigastric pain, nausea and vomiting. Early gastrofiberscopy was performed in all patients. After detection of the larva of Anisakis on gastric mucosa, endoscopic extraction of the larva by biopsy forcep was successfully carried out in all patients. Clinical symptoms were immediately improved after the removal of larva. We believe that it is very important to perform endoscopic examination and extraction of the larva at the earliest possible opportunity. It is emphasized that endoscopic extraction of the larva is the most effective procedure in dealing with acute gastric anisakiasis.

      • KCI등재후보

        VDT작업별 정신사회적 스트레스와 근골격계 장애에 관한 연구

        백남종,강종두,주영수,배인근,권호장,박종만,조수헌,김돈규,김재용,최홍렬 大韓産業醫學會 1998 대한직업환경의학회지 Vol.10 No.4

        It has been hypothesized that jobs that have both high psychological demands and low decision latitude("job strain") can lead to musculoskeletal disorder. The objective of this study was to test whether job strain was correlated with the presence of work-related musculoskeletal disorder, especially myofascial pain syndrome(MPS). Information on demographic factors, confounders such as household load and taking care of children or not, and scores for decision latitude, job demand, and social support was obtained by self-administered questionnaire, which had been developed in Korean language, by adopting NIOSH instrument and Extended Karasek Model(16 items). All subjects were also examined by rehabilitation medicine specialists for musculoskeletal disorders. Subjects(n=370) could be categorized into 4 groups, these were, housewives(n=89), shipyard CAD workers(n=89), general female workers(n=79; nurses, insurance counselors, public officials, clerks, etc), and telephone directory assistance operators(n=113). Results from univariate analyses indicated that all demographic factors, all confounders, scores for decision latitude and social support were not associated with the risk of musculoskeletal disorder. However, score for job demand was higher in musculoskeletal disorder cases than others. In subgroup analysis, this association was convinced again, in telephone directory assistance operators. Job strain model showed that the group of telephone directory assistance operators was high-stain group, and OR of musculo skeletal disorder was 2.446(95% C. I. : 1.174, 5.096), when comparing this with the low strain group. In conclusion, job strain is a risk factor for work-related musculoskeletal disorder.

      • KCI등재후보

        폐암에 의한 기관지 폐쇄의 레이저 Phototherapy 1 예

        한준열,백남종,박성학,박석영,김석영,임계순 대한내과학회 1987 대한내과학회지 Vol.33 No.4

        Major bronchial obstruction by lung cancer is troublesome. Radiation therapy has been the choice of treatment, but it may take long time until relieving bronchial obstruction and has some complications. Recently, laser phototherapy is applied to treatment of malignant obstruction by lung cancer and esophageal cancer, and with increasing frequency and with promising short-term results and acceptable complication rates. We experienced a case of laser phototherapy of malignant airway obstruction of left main bronchus due to squamous cell carcinoma. A 60-year old woman was admitted to the hospital because of dyspnea. Three times of laser phototherapy with Nd-YAG laser was performed with intervals more than three days. The bronchial obstruction was relieved and the procedure was very tolerable.

      • KCI등재후보

        PTCD 후에 발생한 Biloma 1 예

        박동준,김성수,김부성,심규식,백남종,한현복,강동헌,서정민 대한내과학회 1991 대한내과학회지 Vol.41 No.5

        The term $quot;biloma$quot; was introduced in 1979 by L. Gould and A. Patel to describe a loculated collection of bile located outside the biliary tree. The underlying causes are iatrogenic, traumatic, and spontaneous rupture of the bile duct system. The diagnostic methods are clinical history and physical examination, ultrasound, computered tomography, HIDA scintigram, and character of the material obtained by aspiration. Pecutaneous drainage is an effective form of therapy that often eliminates the need for surgical drainage. We experienced a case of biloma after percutaneous transhepatic biliary drainage in a patient with extrahepatic biliary obstruction due to advanced gallbladder carcinoma and present a report with a review of the literature.

      • KCI등재

        작업관련성 수근관증후근 감시체계

        정우철,권호장,하미나,노상철,권범선,현정근,이성재,이종민,권정이,김준성,백남종,이호,이경우,이삼규 大韓産業醫學會 2004 대한직업환경의학회지 Vol.16 No.1

        목적: 작업관련 근골격계질환은 중요한 직업관련성 질환 중의 하나이고 작업관련 수근관증후군은 이러한 작업관련 근골격계질환 중에서도 많은 부분을 차지한다. 이 연구는 작업관련 수근관증후군의 역학적 특성에 대해 알아보고자 수행되었다. 방법: 본 연구에서는 '수근관증후군 감시체계'를 통해 2000년 6월부터 2003년 2월까지 보고 된 672례의 수근관증후군 사례를 분석하였다. 직업력이 확인된 314명을 대상으로는 직업 및 작업내용에 따라 작업관련성 수근관증후군의 비율이 어떻게 달라지는지를 분석함으로써 수근관증후군 위험요인을 조사하였다. 결과: 직업력이 확인된 314명의 환자 중 작업 관련성이 의심되는 사람은 228명 (72.6%) 이었다. 직업별로는 '단순노무종사자', '농림어업숙련자', '서비스종사자' 등에서 작업관련 수근관증후군의 비율이 여성에서 유의하게 높게 나타났으나 연령, 비만도 지수, 과거병력 등에 따른 차이는 관찰되지 않았다. 주관적 증상 중에 '손을 많이 사용한 후 심해진다'와 '손을 털면 덜해진다'라는 항목을 작업관련성 수근관증후군 환자에서 더 많이 호소하였고 다른 증상은 별다른 차이를 보이지 않았다. 작업관련성 수근관증후군 환자가 비교적 많이 노출되는 작업은 '지나치게 손을 뻗쳐서 하는 일', '손을 불편한자세로 유지하는 일' 등이었다. 결론: 전체 수근관증후군 중 작업관련성이 있다는 비율이 매우 높은 것을 확인할 수 있었다. 수근관증후군 감시체계가 작업관련성 수근관증후군의 여러 특성을 밝히는데 매우 효과적인 것으로 나타났으나 현재까지는 중재 대상을 구체적으로 특정하기에는 한계가 있다. Objectives: Carpal tunnel syndrome (CTS) is one of the most important work related musculo-skeletal diseases in Korea. However, there are few epidemiologic studies on the work-related CTS (WR-CTS). This study aimed to investigate the epidemiologic characteristics of WR-CTS in Korea. Methods: Data obtained from the "CTS Surveillance System". Physician case-reports in the surveillance were used to document patterns of WR-CTS by age, gender, occupation, sign, symptom, working history. Results: Six hundred and seventy-two cases of WR-CTS were ascertained of which 3 14 with complete information on occupational history were analyzed. It has been estimated that as many as 72% of' all CTS cases are work-related. The highest proportion of WR-CTS was observed in 'elementary occupation workers', followed by 'skilled agricultural, forestry and fishery worker'. The distributions of WR-CTS cases were similar with respect to age, obesity, and past medical history. The proportion of WR-CTS was higher in females. There was no significant difference in physical examination findings between WR-CTS and non WR-CTS cases. Repetitive work and the inappropriate hand posture seemed to be the risks for WR-CTS. Conclusion: WR-CTS is a significant public health problem. The CTS surveillance system is quite useful to elucidate the characteristics of WR-CTS, but it remains of limited use in targeting specific industries and occupations for intervention.

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