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병원 종사자의 DISC 행동유형 및 스트레스 대처유형과 직무만족, 직무몰입 간의 관계
방기현 ( Kih Hyeon Bang ),장효강 ( Hyo Kang Jang ),정용모 ( Yong Mo Jung ) 한국병원경영학회 2010 병원경영학회지 Vol.15 No.3
The purpose of this study is to analyze the influence of DISC behavior pattern, stress-managing method, and the stress level on job attitude of hospital Employees, and to provide suggestions for effective human resources management in hospital settings. First, the research suggested emotional or aversive stress-managing method had significant influence to the stress level, whereas DISC behavior patterns did not. Second, to the job satisfaction, Influence, Compliance and Steadiness of DISC behavior patterns, challenging or aversive stress-managing method, and the stress level showed immediate meaningful effect. Third, for the system immersion, challenging or emotional ress-managing method as well as the job satisfaction showed direct influence. Especially, the challenging method had not only a direct but an indirect effect through mediating job satisfaction.
이난희 ( Nan-hee Yee ),방기현 ( Ki-hyeon Bang ),송혜숙 ( Hyea-suksong ) 대한보건협회 2017 대한보건연구 Vol.43 No.3
연구목적 : 본 연구의 목적은 종단데이터를 활용한 우리나라 노인의 시간에 따른 우울의 변화를 규명하고, 노인의 우울에 영향을 미치는 요인을 파악하는 것이다. 연구방법 : 연구자료는 한국복지패널 1차년도부터 9차년도까지 데이터이며, 65세 이상 노인 3,775명(남자 노인 1,537명, 여자 노인 2,239명)을 분석 대상으로 하였다. 연구방법은 잠재성장모형과 로지스틱회귀모형을 주로 사용하였다. 통계프로그램으로는 SAS, SPSS, AMOS를 사용하였다. 연구결과 : 노인 우울의 시간이 지남에 따라 점차 감소하고 있으며, 개인간에도 유의한 차이를 보이는 것으로 나타났다. 노인 우울 예측 요인은 여성일수록, 연령이 증가할수록, 배우자가 없는 경우, 저소득층 가구일수록, 건강이 좋지 않은 경우, 음주를 안할수록, 흡연량이 많을수록 높게 나타났고, 이와는 반대로 가족관계만족도와 자아존중감이 높을수록 우울이 낮은 것으로 나타났다. 결론 : 본 연구 결과를 토대로 노인의 우울을 감소시키기 위한 관리방안으로 정책 및 실질적인 개입 방안을 제안하였다. Objective : The purpose of this study is to identify the characteristics of the elderly`s depression and to examine factors affecting the depression of the elderly in Korea. Methods : The research data had targeted 3,775 people aged over 65 years old(male: 1,537, female: 2,239) from 9 waves of the Korea Welfare Panel Study(2006-2014). The main research methods were the Latent Growth Model and the logistic regression model. Statistical programs were used SAS, SPSS and Amos. Results : The level of the elderly`s depression was decreased as time goes and there were differences by personal. In addition, the elderly`s depression tended to increase in the oder, female, no spouse, bad health, and low-income family, lower alcohol consumption, heavy smoker. On the other hand, the elderly`s depression are lowered for those with higher satisfaction, higher family relationship, and higher self-esteem. The factors affecting for the elderly`s depression were health status, family relationship satisfaction, and self-esteem. The highest factor was the self-esteem among them. Conclusions : Based on the findings of this study, we proposed some policy and practical interventions for managing on the elderly`s depression.
Improvement of cellular uptake of hydrophilic molecule, calcein, formulated by liposome
한수민,나영국,이한솔,손기호,전성훈,방기현,김성진,이혜진,조정원 한국약제학회 2018 Journal of Pharmaceutical Investigation Vol.48 No.5
The aim of this study was to prepare the liposome with 1,2-distearoyl-sn-glycero-3-phosphocholine, 1.2 dioleoyl-sn-glycero-3-phosphoethanolamine, cholesteyl hemisuccinate, calcein as a drug model and evaluate physicochemical characteristics such as particle size, polydispersity index (PDI), encapsulation efficiency (EE). Also, the morphology of the blank liposome (without calcein) and the calcein-loaded liposome was observed by a transmission electron microscope (TEM). The particle size and PDI of the blank liposome and the calcein-loaded liposome without tween 80 were 139.8 ± 4.497, 0.31 ± 0.03 and 150.8 ± 8.45, 0.29 ± 0.03 nm, respectively. In addition, it was confirmed that the particle size of the calcein-loaded liposome increased from 294. 6 ± 17.8 to 466.4 ± 78.4 nm when tween 80 was used from 1 to 6%. EE of the calcein-loaded liposome was 66.0 ± 0.58%, independent of the concentration of tween 80. TEM images showed that the shape of the blank liposome and the calcein-loaded liposome was round. In vitro drug release test, calcein from the liposome released approximately 20–25 and 40–50% in pH 7.4 and 4.0, respectively, with a sustained release pattern. The cellular uptake of calcein from the calcein-loaded liposome was about 1.08-fold than that from the calcein solution at 10 μM for a 2 h incubation time. These results suggest that the calcein- loaded liposome was successfully prepared, and could be an application for a hydrophilic drug in further study.